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Felsenstein Medical Research Center, Petach Tikva, Israel
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Felsenstein Medical Research Center, Petach Tikva, Israel
Institute of Gastroenterology, Nutrition and Liver Diseases, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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Felsenstein Medical Research Center, Petach Tikva, Israel
The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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Felsenstein Medical Research Center, Petach Tikva, Israel
The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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undergo either programmed cell death with calcification of the extracellular matrix or trans-differentiation to endochondral osteoblasts, switching from the synthesis of cartilage collagens (mostly type II and X) to the synthesis of type I collagen ( Yang
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Key Laboratory of Molecular Epigenetics of Ministry of Education, Northeast Normal University, Changchun, Jilin, China
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Key Laboratory of Molecular Epigenetics of Ministry of Education, Northeast Normal University, Changchun, Jilin, China
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Key Laboratory of Molecular Epigenetics of Ministry of Education, Northeast Normal University, Changchun, Jilin, China
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( Yamaji et al. 2009 ). PRL binds to prolactin receptor (PRLR) and activates STAT5 through JAK2-regulated phosphorylation. Activated STAT5 (p-STAT5) translocates to nucleus and regulates the expression of alveolar epithelial differentiation
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hormone levels per se that are responsible for phenotypic sexual dimorphisms ranging from growth patterns to expression levels of hepatic enzymes ( Jansson et al . 1985 , Shapiro et al . 1995 ). In the rat, CYP responses to GH regulation are nearly as
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ontogeny analysis, 0 days post hatch (dph), mesonephric gonadal complex (MGC) from 5, 10, 30 and 40 dph larvae ( n = 15) and gonads ( n = 15) from the sexual differentiation stage of 50 dph till adult (50, 100, 150, 200, 250 and 365 dph) were collected
Department of Mathematics, Imperial College London, London SW7 2AZ, UK
Laboratory of Neuroendocrinology, Department of Neurobiology, The Babraham Institute, Babraham, Cambridge CB2 4AT, UK
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Department of Mathematics, Imperial College London, London SW7 2AZ, UK
Laboratory of Neuroendocrinology, Department of Neurobiology, The Babraham Institute, Babraham, Cambridge CB2 4AT, UK
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Department of Mathematics, Imperial College London, London SW7 2AZ, UK
Laboratory of Neuroendocrinology, Department of Neurobiology, The Babraham Institute, Babraham, Cambridge CB2 4AT, UK
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Department of Mathematics, Imperial College London, London SW7 2AZ, UK
Laboratory of Neuroendocrinology, Department of Neurobiology, The Babraham Institute, Babraham, Cambridge CB2 4AT, UK
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Department of Mathematics, Imperial College London, London SW7 2AZ, UK
Laboratory of Neuroendocrinology, Department of Neurobiology, The Babraham Institute, Babraham, Cambridge CB2 4AT, UK
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Department of Mathematics, Imperial College London, London SW7 2AZ, UK
Laboratory of Neuroendocrinology, Department of Neurobiology, The Babraham Institute, Babraham, Cambridge CB2 4AT, UK
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Department of Mathematics, Imperial College London, London SW7 2AZ, UK
Laboratory of Neuroendocrinology, Department of Neurobiology, The Babraham Institute, Babraham, Cambridge CB2 4AT, UK
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Department of Mathematics, Imperial College London, London SW7 2AZ, UK
Laboratory of Neuroendocrinology, Department of Neurobiology, The Babraham Institute, Babraham, Cambridge CB2 4AT, UK
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. Robinson JE , Birch RA, Grindrod JA, Taylor JA & Unsworth WP 2003 Sexually differentiated regulation of GnRH release by gonadal steroid hormones in sheep. Reproduction Supplement 61 299 –310. Rotterdam 2004 Revised 2003
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differentiation of stem cells residing in other organs ( Aguiari et al . 2008 , Vettor et al . 2009 ). The resulting metabolic consequences include abdominal obesity, insulin resistance, and atherogenic dyslipidemia along with a pro-thrombotic, inflammatory
Laboratory Animal Center, Nantong University, Nantong, Jiangsu, China
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School of Traditional Chinese Medicine, China Pharmaceutical University, Nanjing, Jiangsu, China
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Laboratory of Gastrointestinal Microbiology, Jiangsu Key Laboratory of Gastrointestinal Nutrition and Animal Health, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu, China
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differentiation and survival ( Salehi et al. 2000 ), modulate circadian rhythm ( Wang et al. 2010 ) and be involved in depression ( Mouri et al. 2012 ), learning and memory formation ( Yang et al. 2015 ), and social interactions and sexual behavior
Department of Physiology,
Department of Immunology and Microbiology, Faculty of Pharmacy, 450 Vojvode Stepe, 11221 Belgrade, Serbia
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Department of Physiology,
Department of Immunology and Microbiology, Faculty of Pharmacy, 450 Vojvode Stepe, 11221 Belgrade, Serbia
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Department of Physiology,
Department of Immunology and Microbiology, Faculty of Pharmacy, 450 Vojvode Stepe, 11221 Belgrade, Serbia
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Department of Physiology,
Department of Immunology and Microbiology, Faculty of Pharmacy, 450 Vojvode Stepe, 11221 Belgrade, Serbia
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Department of Physiology,
Department of Immunology and Microbiology, Faculty of Pharmacy, 450 Vojvode Stepe, 11221 Belgrade, Serbia
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Department of Physiology,
Department of Immunology and Microbiology, Faculty of Pharmacy, 450 Vojvode Stepe, 11221 Belgrade, Serbia
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Department of Physiology,
Department of Immunology and Microbiology, Faculty of Pharmacy, 450 Vojvode Stepe, 11221 Belgrade, Serbia
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Department of Physiology,
Department of Immunology and Microbiology, Faculty of Pharmacy, 450 Vojvode Stepe, 11221 Belgrade, Serbia
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-releasing hormone production. Journal of Endocrinology 158 229 –235. Beyer C 1987 Sex steroids and afferent input: their roles in brain sexual differentiation. Annual Review of Physiology 49 349 –364
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Pbx1 KO mouse, but remain rudimentary, despite initiation of sexual differentiation. Since SF1 also activates Pbx1 promoter activity, it is possible that the reduced X-zone in Pbx1 haploinsufficiency is due to synergistic actions of these two
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, luteolysis, and testis development, as well as in regulation of FSH-β gene transcription. Activin and gonadal sex determination Emerging evidence suggests that FST and activins influence differentiation of the indifferent gonad as well as the early stages of