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Ruben Rodriguez Department of Molecular & Cellular Biology, University of California, Merced, California, USA

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Jacqueline N Minas Department of Molecular & Cellular Biology, University of California, Merced, California, USA

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Jose Pablo Vazquez-Medina Department of Integrative Biology, University of California, Berkeley, California, USA

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Daisuke Nakano Department of Pharmacology, Kagawa University Medical School, Kagawa, Japan

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David G Parkes DGP Scientific Inc., Del Mar, California, USA

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Akira Nishiyama Department of Pharmacology, Kagawa University Medical School, Kagawa, Japan

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Rudy M Ortiz Department of Molecular & Cellular Biology, University of California, Merced, California, USA

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Improved insulin sensitivity after long-term treatment with at 1 blockers is not associated with pparγ target gene regulation . Endocrinology 153 1103 – 1115 . ( https://doi.org/10.1210/en.2011-0183 ) 10.1210/en.2011-0183 22253423 Müller‐Fielitz H

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Gulizar Issa Ameen Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK

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Silvia Mora Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK

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gene (data not shown). This suggested that oestrogens may contribute to RBP4 gene regulation. To determine whether 17β-estradiol regulates Rbp4 expression in adipocytes, we treated differentiated 3T3L1 adipocytes with increasing concentrations (0, 1

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Yi Jun Desmond Tan Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Faculty of Medicine & Health Sciences, UCSI University, Cheras, Kuala Lumpur, Malaysia

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Danielle L Brooks Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

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Kelly Yin Han Wong Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Faculty of Medicine & Health Sciences, UCSI University, Cheras, Kuala Lumpur, Malaysia

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Yuefei Huang Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

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Jose R Romero Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

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Jonathan S Williams Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

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Luminita H Pojoga Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

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Mueller et al. 2014 ). HTN shows a high degree of heritability with polymorphic variants in a substantial number of genes being associated with HTN. Not surprisingly given our current appreciation of gene regulation, only a small fraction of

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Michael Hastings Division of Neurobiology, MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK

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John S O’Neill Division of Neurobiology, MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK

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Elizabeth S Maywood Division of Neurobiology, MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK

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& McMahon DG 2000 GFP fluorescence reports Period 1 circadian gene regulation in the mammalian biological clock. Neuroreport 11 1479 –1482. Levi F & Schibler U 2007 Circadian rhythms: mechanisms and therapeutic

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Kazunori Kageyama
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Komaki Hanada
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Yasumasa Iwasaki
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Satoru Sakihara
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Takeshi Nigawara
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John Kasckow
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Toshihiro Suda
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. Neuroendocrinology 60 493 –502. Burbach JP , Luckman SM, Murphy D & Gainer H 2001 Gene regulation in the magnocellular hypothalamo-neurohypophysial system. Physiological Reviews 81 1197 –1267. Castell

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Kushaan Dumasia Department of Neuroendocrinology, National Institute for Research in Reproductive Health (Indian Council of Medical Research), Parel, Mumbai 400 012, India

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Anita Kumar Department of Neuroendocrinology, National Institute for Research in Reproductive Health (Indian Council of Medical Research), Parel, Mumbai 400 012, India

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Leena Kadam Department of Neuroendocrinology, National Institute for Research in Reproductive Health (Indian Council of Medical Research), Parel, Mumbai 400 012, India

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N H Balasinor Department of Neuroendocrinology, National Institute for Research in Reproductive Health (Indian Council of Medical Research), Parel, Mumbai 400 012, India

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Garlick C Ben-Jonathan N 1998 Cellular distribution and gene regulation of estrogen receptors α and β in the rat pituitary gland . Endocrinology 139 3976 – 3983 . ( doi:10.1210/endo.139.9.6181 ) Oliveira C Zhou Q Carnes K Nie R Kuehl

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Anaies Nazarians-Armavil Departments of Physiology, Obstetrics and Gynaecology, Medicine, Division of Cellular and Molecular Biology

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Jennifer A Chalmers Departments of Physiology, Obstetrics and Gynaecology, Medicine, Division of Cellular and Molecular Biology

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Claire B Lee Departments of Physiology, Obstetrics and Gynaecology, Medicine, Division of Cellular and Molecular Biology

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Wenqing Ye Departments of Physiology, Obstetrics and Gynaecology, Medicine, Division of Cellular and Molecular Biology

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Denise D Belsham Departments of Physiology, Obstetrics and Gynaecology, Medicine, Division of Cellular and Molecular Biology
Departments of Physiology, Obstetrics and Gynaecology, Medicine, Division of Cellular and Molecular Biology
Departments of Physiology, Obstetrics and Gynaecology, Medicine, Division of Cellular and Molecular Biology
Departments of Physiology, Obstetrics and Gynaecology, Medicine, Division of Cellular and Molecular Biology

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Pomc mRNA expression in mHypoA-POMC/GFP-1 neurons To test the mHypoA-POMC/GFP-1 cell model for viability for gene regulation studies, we treated the cells with 10 ng/ml CNTF or 10 nM insulin and assessed mRNA expression levels of c-fos ( Fos ), a

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O Sukocheva Division of Surgery, Children's Cancer Institute Australia, Flinders University of South Australia, Bedford Park, South Australia 5042, Australia

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C Wadham Division of Surgery, Children's Cancer Institute Australia, Flinders University of South Australia, Bedford Park, South Australia 5042, Australia

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potential transcription factor binding sites have been identified in the SPHK promoter region, including Sp1, AP1, AP2, AP4 and STAT ( Nakade et al . 2003 , Sobue et al . 2005 ). However, which transcription factors account for the SPHK gene

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Bethany P Cummings
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Ahmed Bettaieb Department of Biomedical Sciences, Department of Molecular Biosciences, Department of Nutrition, Department of Internal Medicine, College of Veterinary Medicine, Cornell University, T7 022A Veterinary Research Tower (Box 17), Ithaca, New York 14850, USA

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James L Graham Department of Biomedical Sciences, Department of Molecular Biosciences, Department of Nutrition, Department of Internal Medicine, College of Veterinary Medicine, Cornell University, T7 022A Veterinary Research Tower (Box 17), Ithaca, New York 14850, USA
Department of Biomedical Sciences, Department of Molecular Biosciences, Department of Nutrition, Department of Internal Medicine, College of Veterinary Medicine, Cornell University, T7 022A Veterinary Research Tower (Box 17), Ithaca, New York 14850, USA

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Kimber Stanhope Department of Biomedical Sciences, Department of Molecular Biosciences, Department of Nutrition, Department of Internal Medicine, College of Veterinary Medicine, Cornell University, T7 022A Veterinary Research Tower (Box 17), Ithaca, New York 14850, USA
Department of Biomedical Sciences, Department of Molecular Biosciences, Department of Nutrition, Department of Internal Medicine, College of Veterinary Medicine, Cornell University, T7 022A Veterinary Research Tower (Box 17), Ithaca, New York 14850, USA

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Fawaz G Haj Department of Biomedical Sciences, Department of Molecular Biosciences, Department of Nutrition, Department of Internal Medicine, College of Veterinary Medicine, Cornell University, T7 022A Veterinary Research Tower (Box 17), Ithaca, New York 14850, USA
Department of Biomedical Sciences, Department of Molecular Biosciences, Department of Nutrition, Department of Internal Medicine, College of Veterinary Medicine, Cornell University, T7 022A Veterinary Research Tower (Box 17), Ithaca, New York 14850, USA

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Peter J Havel Department of Biomedical Sciences, Department of Molecular Biosciences, Department of Nutrition, Department of Internal Medicine, College of Veterinary Medicine, Cornell University, T7 022A Veterinary Research Tower (Box 17), Ithaca, New York 14850, USA
Department of Biomedical Sciences, Department of Molecular Biosciences, Department of Nutrition, Department of Internal Medicine, College of Veterinary Medicine, Cornell University, T7 022A Veterinary Research Tower (Box 17), Ithaca, New York 14850, USA

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Kovacs LG Graves RA 1996 Differentiation-dependent expression of the brown adipocyte uncoupling protein gene: regulation by peroxisome proliferator-activated receptor γ . Molecular and Cellular Biology 16 3410 – 3419 . Sell H Berger JP

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A D Dobrian Departments of Physiological Sciences, Microbiology and Molecular Cell Biology, Internal Medicine, Division of Inflammation Biology, Eastern Virginia Medical School, 700W Olney Road, Norfolk, Virginia 23505, USA

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M A Hatcher Departments of Physiological Sciences, Microbiology and Molecular Cell Biology, Internal Medicine, Division of Inflammation Biology, Eastern Virginia Medical School, 700W Olney Road, Norfolk, Virginia 23505, USA

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J J Brotman Departments of Physiological Sciences, Microbiology and Molecular Cell Biology, Internal Medicine, Division of Inflammation Biology, Eastern Virginia Medical School, 700W Olney Road, Norfolk, Virginia 23505, USA

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E V Galkina Departments of Physiological Sciences, Microbiology and Molecular Cell Biology, Internal Medicine, Division of Inflammation Biology, Eastern Virginia Medical School, 700W Olney Road, Norfolk, Virginia 23505, USA

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P Taghavie-Moghadam Departments of Physiological Sciences, Microbiology and Molecular Cell Biology, Internal Medicine, Division of Inflammation Biology, Eastern Virginia Medical School, 700W Olney Road, Norfolk, Virginia 23505, USA

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H Pei Departments of Physiological Sciences, Microbiology and Molecular Cell Biology, Internal Medicine, Division of Inflammation Biology, Eastern Virginia Medical School, 700W Olney Road, Norfolk, Virginia 23505, USA

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B A Haynes Departments of Physiological Sciences, Microbiology and Molecular Cell Biology, Internal Medicine, Division of Inflammation Biology, Eastern Virginia Medical School, 700W Olney Road, Norfolk, Virginia 23505, USA

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J L Nadler Departments of Physiological Sciences, Microbiology and Molecular Cell Biology, Internal Medicine, Division of Inflammation Biology, Eastern Virginia Medical School, 700W Olney Road, Norfolk, Virginia 23505, USA

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consequences of a high-fat diet in mice . Hypertension 55 715 – 721 . ( doi:10.1161/HYPERTENSIONAHA.109.148049 ) Darnell JE Jr 1997 STATs and gene regulation . Science 277 1630 – 1635 . ( doi:10.1126/science.277.5332.1630 ) Davenport P

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