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Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois, USA
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Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois, USA
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that SCFAs are able to carry out their physiological effects is through binding to their cognate receptors, including FFA2. FFA2 is broadly expressed in many metabolically active tissues, including the intestine, endocrine pancreas, adipose tissue and
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Department of Diabetes and Endocrinology, Department of Medicine, Ophthalmology and Visual Sciences, Internal Medicine, King's College London School of Medicine, London, UK
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Department of Diabetes and Endocrinology, Department of Medicine, Ophthalmology and Visual Sciences, Internal Medicine, King's College London School of Medicine, London, UK
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TSHR and IGF1R ( Bell et al . 2000 , Zhang et al . 2009 ) and represent the key participants in orbital tissue remodeling in GO ( Smith 2003 ), Recently, bone marrow-derived CD34 + fibrocytes have been detected among the fibroblasts inhabiting the
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shown that cultured intermuscular adipocytes produce pro-diabetic substances, providing evidence of a causal relationship ( Laurens et al. 2016 ). Additionally, a mechanistic link between expansion of visceral adipose tissue and muscle atrophy has been
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Exercise Health and Performance, Faculty of Health and Medical Sciences, Department of Neuroscience and Pharmacology, School of Medicine and Pharmacology, UMR CNRS 9214, Physiology Department, Department of Endocrinology, Inflammation and Infection Research, Faculty of Health Sciences, and Charles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia
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Exercise Health and Performance, Faculty of Health and Medical Sciences, Department of Neuroscience and Pharmacology, School of Medicine and Pharmacology, UMR CNRS 9214, Physiology Department, Department of Endocrinology, Inflammation and Infection Research, Faculty of Health Sciences, and Charles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia
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from EPO-treated animals resulted from an indirect action of EPO on this tissue. Figure 6 While EPOR is expressed in muscle cells, EPO does not stimulate glucose uptake or glycogen synthesis in cultured myotubes. (A) EPOR expression in bone marrow
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the generation of autoimmune responses. Stem/progenitor cells derived from bone marrow It has also been suggested that in many high- and low-proliferating organs, stem/progenitor cells are furnished by bone marrow ( Sherwood et al . 2004 , Klonisch
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Introduction The hematopoietic growth factor erythropoietin (EPO) is produced in the kidney in response to hypoxia, and stimulates erythropoiesis in the bone marrow ( Krantz 1991 , Spivak et al . 1991 ). Recombinant human EPO (rHuEPO) is an
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the experiment, liver and gonadal deposits of white adipose tissue and interscapular deposits of brown adipose tissue were dissected from mice and their weights were determined using an analytical scale (Analytical Standard Electric Balance, Ohaus, NJ
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be involved in the elevated risk of HF. Both visceral obesity and ectopic fat accumulation in non-adipose tissues, including the heart, have been related to cardiac structure abnormalities and increased cardiometabolic risk ( Britton & Fox 2011
Microbiology and Molecular Cell Biology,
Anatomy and Pathology, Eastern Virginia Medical School, 855 W Brambleton Avenue, Norfolk, 23510 Virginia, USA
NIDDK, NIH, DHHS, Mark O Hatfield Clinical Research Center, Room 5-5940, Bethesda, Maryland 20892, USA
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Microbiology and Molecular Cell Biology,
Anatomy and Pathology, Eastern Virginia Medical School, 855 W Brambleton Avenue, Norfolk, 23510 Virginia, USA
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Microbiology and Molecular Cell Biology,
Anatomy and Pathology, Eastern Virginia Medical School, 855 W Brambleton Avenue, Norfolk, 23510 Virginia, USA
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Microbiology and Molecular Cell Biology,
Anatomy and Pathology, Eastern Virginia Medical School, 855 W Brambleton Avenue, Norfolk, 23510 Virginia, USA
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Microbiology and Molecular Cell Biology,
Anatomy and Pathology, Eastern Virginia Medical School, 855 W Brambleton Avenue, Norfolk, 23510 Virginia, USA
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stomach, spleen, duodenum, liver, kidney, lung, skeletal muscle, brain, heart, or bone marrow (data not shown). Since endogenous elastase is also detected in the stomach ( Kruse et al. 1993 ), this expression pattern supports a restricted expression of
Division of Hematology/Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 5, Fu-Hsing Street, Taoyuan 333, Taiwan
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Division of Hematology/Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 5, Fu-Hsing Street, Taoyuan 333, Taiwan
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Division of Hematology/Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 5, Fu-Hsing Street, Taoyuan 333, Taiwan
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Division of Hematology/Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 5, Fu-Hsing Street, Taoyuan 333, Taiwan
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Division of Hematology/Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 5, Fu-Hsing Street, Taoyuan 333, Taiwan
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Introduction Cachexia is a paraneoplastic syndrome manifested as progressive weight loss with depletion of adipose tissue and skeletal muscle, and contributes to a poor quality of life, which is observed in about half of all the