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Local impact of thyroid hormone inactivation

Deiodinases: the balance of thyroid hormone

Monica Dentice Department of Molecular and Clinical Endocrinology and Oncology, University of Naples ‘Federico II’, Via S. Pansini 5, 80131 Naples, Italy

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Domenico Salvatore Department of Molecular and Clinical Endocrinology and Oncology, University of Naples ‘Federico II’, Via S. Pansini 5, 80131 Naples, Italy

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. Implications for developmental gene regulation . Journal of Biological Chemistry 280 41222 – 41228 doi:10.1074/jbc.M509593200 . Campos-Barros A Amma LL Faris JS Shailam R Kelley MW Forrest D 2000 Type 2 iodothyronine deiodinase expression

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Pia Kiilerich Institute of Biology, Department of Biology, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark

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Christian K Tipsmark Institute of Biology, Department of Biology, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark
Institute of Biology, Department of Biology, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark

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Russell J Borski Institute of Biology, Department of Biology, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark

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Steffen S Madsen Institute of Biology, Department of Biology, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark

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-osmoregulation in both species. DOC has distinct as well as overlapping actions on ion transporter gene regulation, suggesting that the two corticosteroids may coordinate their actions, presumably through distinct GR and MR receptors to accurately regulate target

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Hyun Joon Kim Division of Reproductive Sciences, Department of Anatomy and Neurobiology, Department of Biology, Department of Animal Science and Environment, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, Institut Clinique de la Souris, Department of Obstetrics, Department of Molecular and Biomedical Pharmacology, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA
Division of Reproductive Sciences, Department of Anatomy and Neurobiology, Department of Biology, Department of Animal Science and Environment, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, Institut Clinique de la Souris, Department of Obstetrics, Department of Molecular and Biomedical Pharmacology, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA

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Mary C Gieske Division of Reproductive Sciences, Department of Anatomy and Neurobiology, Department of Biology, Department of Animal Science and Environment, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, Institut Clinique de la Souris, Department of Obstetrics, Department of Molecular and Biomedical Pharmacology, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA
Division of Reproductive Sciences, Department of Anatomy and Neurobiology, Department of Biology, Department of Animal Science and Environment, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, Institut Clinique de la Souris, Department of Obstetrics, Department of Molecular and Biomedical Pharmacology, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA

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Kourtney L Trudgen Division of Reproductive Sciences, Department of Anatomy and Neurobiology, Department of Biology, Department of Animal Science and Environment, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, Institut Clinique de la Souris, Department of Obstetrics, Department of Molecular and Biomedical Pharmacology, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA

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Susan Hudgins-Spivey Division of Reproductive Sciences, Department of Anatomy and Neurobiology, Department of Biology, Department of Animal Science and Environment, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, Institut Clinique de la Souris, Department of Obstetrics, Department of Molecular and Biomedical Pharmacology, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA

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Beob Gyun Kim Division of Reproductive Sciences, Department of Anatomy and Neurobiology, Department of Biology, Department of Animal Science and Environment, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, Institut Clinique de la Souris, Department of Obstetrics, Department of Molecular and Biomedical Pharmacology, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA

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Andree Krust Division of Reproductive Sciences, Department of Anatomy and Neurobiology, Department of Biology, Department of Animal Science and Environment, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, Institut Clinique de la Souris, Department of Obstetrics, Department of Molecular and Biomedical Pharmacology, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA
Division of Reproductive Sciences, Department of Anatomy and Neurobiology, Department of Biology, Department of Animal Science and Environment, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, Institut Clinique de la Souris, Department of Obstetrics, Department of Molecular and Biomedical Pharmacology, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA

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Pierre Chambon Division of Reproductive Sciences, Department of Anatomy and Neurobiology, Department of Biology, Department of Animal Science and Environment, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, Institut Clinique de la Souris, Department of Obstetrics, Department of Molecular and Biomedical Pharmacology, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA
Division of Reproductive Sciences, Department of Anatomy and Neurobiology, Department of Biology, Department of Animal Science and Environment, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, Institut Clinique de la Souris, Department of Obstetrics, Department of Molecular and Biomedical Pharmacology, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA

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Jae-Wook Jeong Division of Reproductive Sciences, Department of Anatomy and Neurobiology, Department of Biology, Department of Animal Science and Environment, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, Institut Clinique de la Souris, Department of Obstetrics, Department of Molecular and Biomedical Pharmacology, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA

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Eric Blalock Division of Reproductive Sciences, Department of Anatomy and Neurobiology, Department of Biology, Department of Animal Science and Environment, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, Institut Clinique de la Souris, Department of Obstetrics, Department of Molecular and Biomedical Pharmacology, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA

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CheMyong Ko Division of Reproductive Sciences, Department of Anatomy and Neurobiology, Department of Biology, Department of Animal Science and Environment, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, Institut Clinique de la Souris, Department of Obstetrics, Department of Molecular and Biomedical Pharmacology, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA
Division of Reproductive Sciences, Department of Anatomy and Neurobiology, Department of Biology, Department of Animal Science and Environment, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, Institut Clinique de la Souris, Department of Obstetrics, Department of Molecular and Biomedical Pharmacology, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA

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and gene regulation of estrogen receptors alpha and beta in the rat pituitary gland . Endocrinology 139 3976 – 3983 doi:10.1210/en.139.9.3976 . Morand I Fonlupt P Guerrier A Trouillas J Calle A Remy C Rousset B Munari-Silem Y

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Suzana T Cunha Lima Diabetes Center, Instituto de Biologia, Centro Universitário da Bahia ‐ FIB, University of California, 513 Parnassus Avenue, 94143 San Francisco, California, USA
Diabetes Center, Instituto de Biologia, Centro Universitário da Bahia ‐ FIB, University of California, 513 Parnassus Avenue, 94143 San Francisco, California, USA

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Edson D Rodrigues Diabetes Center, Instituto de Biologia, Centro Universitário da Bahia ‐ FIB, University of California, 513 Parnassus Avenue, 94143 San Francisco, California, USA
Diabetes Center, Instituto de Biologia, Centro Universitário da Bahia ‐ FIB, University of California, 513 Parnassus Avenue, 94143 San Francisco, California, USA

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that this species should respond more rapidly to alterations in intracellular T 3 than other TR species. Furthermore, the fact that TR dimers are resistant to T 3 binding is consistent with previous proposals that this species is important for gene

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Charles A Ducsay
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Dean A Myers Center for Perinatal Biology, Department of Obstetrics and Gynecology, Loma Linda University School of Medicine, Loma Linda, California 92350, USA

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as molecular targets for nitric oxide-mediated gene regulation . Antioxidants and Redox Signaling 3 565 – 575 doi:10.1089/15230860152542934 . Lamanna C Assisi L Vittoria A Botte V Di Fiore MM 2007 d -Aspartic acid and nitric oxide

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Andrew L Pierce
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Jason P Breves
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Shunsuke Moriyama Hawaii Institute of Marine Biology, School of Marine Biosciences, University of Hawaii, Kaneohe, Hawaii 96744, USA

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Tetsuya Hirano
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E Gordon Grau
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gene regulation. In mammals, current models suggest that GH stimulation of liver Igf1 transcription is mediated by binding of the transcription factor Stat5b to multiple enhancer sites dispersed across at least 135 kb throughout the Igf1 locus

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Karolína Liška Laboratory of Biological Rhythms, Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic
Third Faculty of Medicine, Charles University, Prague, Czech Republic

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Martin Sládek Laboratory of Biological Rhythms, Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic

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Vendula Čečmanová Laboratory of Biological Rhythms, Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic

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Alena Sumová Laboratory of Biological Rhythms, Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic

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Guilchicek E Wilczak-Havill K Nairn A Williams K Sass S 2012 A molecular characterization of the choroid plexus and stress-induced gene regulation . Translational Psychiatry 2 e139 – e139 . ( https://doi.org/10.1038/tp.2012.64 ) Segall

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Zhengxiang Huang School of Biomedical Sciences, University of Queensland, St Lucia, Brisbane, Australia

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Lili Huang School of Biomedical Sciences, University of Queensland, St Lucia, Brisbane, Australia

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Chengjian Wang School of Biomedical Sciences, University of Queensland, St Lucia, Brisbane, Australia

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Shanli Zhu School of Biomedical Sciences, University of Queensland, St Lucia, Brisbane, Australia

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Xinzhou Qi School of Biomedical Sciences, University of Queensland, St Lucia, Brisbane, Australia

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Yang Chen School of Biomedical Sciences, University of Queensland, St Lucia, Brisbane, Australia

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Yanjun Zhang School of Information Technology and Electrical Engineering, University of Queensland, St Lucia, Brisbane, Australia

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Michael A Cowley Department of Physiology, Monash University, Melbourne, Australia

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Johannes D Veldhuis Department of Medicine, Endocrine Research Unit, Mayo School of Graduate Medical Education, Clinical Translational Science Center, Mayo Clinic, Rochester, Minnesota, USA

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Chen Chen School of Biomedical Sciences, University of Queensland, St Lucia, Brisbane, Australia

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://doi.org/10.3389/fendo.2013.00037 ) Chia DJ 2014 Minireview: mechanisms of growth hormone-mediated gene regulation . Molecular Endocrinology 28 1012 – 1025 . ( https://doi.org/10.1210/me.2014-1099 ) Chiba Y Yamada T Tsukita S Takahashi K

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Anne-Marie Neumann Institute of Neurobiology, University of Lübeck, Lübeck, Germany
Center of Brain, Behavior and Metabolism, University of Lübeck, Lübeck, Germany

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Cathleen Geißler Center of Brain, Behavior and Metabolism, University of Lübeck, Lübeck, Germany
Institute for Human Genetics, Epigenetics and Metabolism Lab, University of Lübeck, Lübeck, Germany

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Violetta Pilorz Institute of Neurobiology, University of Lübeck, Lübeck, Germany
Center of Brain, Behavior and Metabolism, University of Lübeck, Lübeck, Germany

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Iwona Olejniczak Institute of Neurobiology, University of Lübeck, Lübeck, Germany
Center of Brain, Behavior and Metabolism, University of Lübeck, Lübeck, Germany

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Alfor G Lewis Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA

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Randy J Seeley Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA

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Orr Shomroni Transcriptome and Genome Analysis Core Unit, University Medical Center Göttingen, Göttingen, Germany

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Gabriela Salinas-Riester Transcriptome and Genome Analysis Core Unit, University Medical Center Göttingen, Göttingen, Germany

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Henriette Kirchner Center of Brain, Behavior and Metabolism, University of Lübeck, Lübeck, Germany
Institute for Human Genetics, Epigenetics and Metabolism Lab, University of Lübeck, Lübeck, Germany
German Center for Diabetes Research (DZD), Helmholtz Zentrum München, Bayern, Germany

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Henrik Oster Institute of Neurobiology, University of Lübeck, Lübeck, Germany
Center of Brain, Behavior and Metabolism, University of Lübeck, Lübeck, Germany

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transcriptome rhythms, core clock gene regulation ( Fig. 6F , G , H , I , J , K , L and M ) was largely unaffected by surgery – with the noted exception of Clock ( Fig. 6G ; amplitude VSG: 206.1 vs sham: 162.0, mean expression VSG: 1.337 ± 65 vs sham: 1

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Zhengxiang Huang School of Biomedical Sciences, University of Queensland, Queensland, Australia

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Xuehan Lu School of Biomedical Sciences, University of Queensland, Queensland, Australia

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Lili Huang School of Biomedical Sciences, University of Queensland, Queensland, Australia

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Yang Chen School of Biomedical Sciences, University of Queensland, Queensland, Australia

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Chunhong Zhang School of Biomedical Sciences, University of Queensland, Queensland, Australia

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Johannes D Veldhuis Department of Medicine, Endocrine Research Unit, Mayo School of Graduate Medical Education, Clinical Translational Science Center, Mayo Clinic Rochester, Rochester, Minnesota, USA

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Chen Chen School of Biomedical Sciences, University of Queensland, Queensland, Australia

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. ( https://doi.org/10.14573/altex.1309231 ) Chia DJ 2014 Minireview: mechanisms of growth hormone-mediated gene regulation . Molecular Endocrinology 28 1012 – 10 25 . ( https://doi.org/10.1210/me.2014-1099 ) Clasey JL Weltman A Patrie J

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