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Nigel Turner Department of Pharmacology, School of Medical Sciences, Diabetes and Obesity Division, St Vincent's Clinical School, Department of Physiology, University of New South Wales, Sydney, New South Wales, Australia
Department of Pharmacology, School of Medical Sciences, Diabetes and Obesity Division, St Vincent's Clinical School, Department of Physiology, University of New South Wales, Sydney, New South Wales, Australia

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Gregory J Cooney Department of Pharmacology, School of Medical Sciences, Diabetes and Obesity Division, St Vincent's Clinical School, Department of Physiology, University of New South Wales, Sydney, New South Wales, Australia
Department of Pharmacology, School of Medical Sciences, Diabetes and Obesity Division, St Vincent's Clinical School, Department of Physiology, University of New South Wales, Sydney, New South Wales, Australia

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Edward W Kraegen Department of Pharmacology, School of Medical Sciences, Diabetes and Obesity Division, St Vincent's Clinical School, Department of Physiology, University of New South Wales, Sydney, New South Wales, Australia
Department of Pharmacology, School of Medical Sciences, Diabetes and Obesity Division, St Vincent's Clinical School, Department of Physiology, University of New South Wales, Sydney, New South Wales, Australia

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Clinton R Bruce Department of Pharmacology, School of Medical Sciences, Diabetes and Obesity Division, St Vincent's Clinical School, Department of Physiology, University of New South Wales, Sydney, New South Wales, Australia

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that circadian processes in tissues could be regulated directly by some inputs. Some mouse models with genetic manipulations of core clock genes have altered circadian rhythms and are more prone to developing obesity ( Turek et al . 2005 , Kennaway

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-13-0397
Volume/Issue:
Volume 220: Issue 2
Free access
Victoria Diedrich Institute of Neurobiology, Ulm University, Ulm, Germany

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Elena Haugg Institute of Neurobiology, Ulm University, Ulm, Germany

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Carola Dreier Institute of Neurobiology, Ulm University, Ulm, Germany

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Annika Herwig Institute of Neurobiology, Ulm University, Ulm, Germany

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et al. 2016 ). The precise circadian control of short spontaneous daily torpor expression in Djungarian hamsters implicates a role for the suprachiasmatic nucleus - the master circadian clock and main driver of all endogenous rhythms - in torpor

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-19-0502
Volume/Issue:
Volume 244: Issue 2
Free access
Alberto Dinarello Department of Biology, University of Padova, Padova, Italy

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Giorgio Licciardello Department of Biology, University of Padova, Padova, Italy

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Camilla Maria Fontana Department of Biology, University of Padova, Padova, Italy

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Natascia Tiso Department of Biology, University of Padova, Padova, Italy

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Francesco Argenton Department of Biology, University of Padova, Padova, Italy

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Luisa Dalla Valle Department of Biology, University of Padova, Padova, Italy

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mirror the oscillations of basal cortisol concentrations with the circadian rhythm ( Krug et al. 2014 ). Almost simultaneously, Benato et al . generated the Tg(9GCRE-HSV.Ul23:EGFP) ia20 transgenic zebrafish line, from herein named ia20 . The

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-20-0173
Volume/Issue:
Volume 247: Issue 3
Free access
Kanta Kon Department of Clinical Pharmacology, University of Toyama, Sugitani, Toyama, Japan

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Hiroshi Tsuneki Department of Clinical Pharmacology, University of Toyama, Sugitani, Toyama, Japan

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Hisakatsu Ito Department of Anesthesiology, University of Toyama, Sugitani, Toyama, Japan

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Yoshinori Takemura Department of Anesthesiology, University of Toyama, Sugitani, Toyama, Japan

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Kiyofumi Sato Department of Clinical Pharmacology, University of Toyama, Sugitani, Toyama, Japan

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Mitsuaki Yamazaki Department of Anesthesiology, University of Toyama, Sugitani, Toyama, Japan

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Yoko Ishii Department of Pathology, University of Toyama, Sugitani, Toyama, Japan

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Masakiyo Sasahara Department of Pathology, University of Toyama, Sugitani, Toyama, Japan

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Assaf Rudich Department of Clinical Biochemistry and Pharmacology, Ben-Gurion University of the Negev, Beer-Sheva, Israel

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Takahiro Maeda Department of Clinical Pharmacology, University of Toyama, Sugitani, Toyama, Japan

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Tsutomu Wada Department of Clinical Pharmacology, University of Toyama, Sugitani, Toyama, Japan

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Toshiyasu Sasaoka Department of Clinical Pharmacology, University of Toyama, Sugitani, Toyama, Japan

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of these drugs are required for promoting physiological sleep–wake cycle. Synchronization of sleep–wake behavior with circadian clock rhythm is required for maintaining glucose homeostasis ( Gamble et al. 2014 ). Impaired sleep quality is

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0708
Volume/Issue:
Volume 243: Issue 1
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Daniela Leite de Oliveira Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil

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Camila Hirotsu Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil

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Sergio Tufik Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil

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Monica Levy Andersen Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil

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circadian rhythms. The absence of light stimulates melatonin production, leading to sleep facilitation. During the daytime, the light stimulus is processed by the retina and sent to the suprachiasmatic nucleus, inhibiting melatonin synthesis and promoting

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-16-0514
Volume/Issue:
Volume 234: Issue 1
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Greisa Vila
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Michaela Riedl
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Michael Resl
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Aart Jan van der Lely Division of Endocrinology and Metabolism, Division of Endocrinology, Department of Internal Medicine III, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria

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Leo J Hofland Division of Endocrinology and Metabolism, Division of Endocrinology, Department of Internal Medicine III, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria

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Martin Clodi
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Anton Luger
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reproductive functions, and is a classical stress hormone ( Gimpl & Fahrenholz 2001 , Landgraf & Neumann 2004 ). Plasma OXT displays a distinct circadian rhythm and changes during stress response, parturition and lactation, as well as upon pharmacological use

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-09-0227
Volume/Issue:
Volume 203: Issue 1
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Gary B Silberstein Department of Molecular, Cell and Developmental Biology, Sinsheimer Laboratories, University of California, Santa Cruz, California 95064, USA

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Katharine Van Horn Department of Molecular, Cell and Developmental Biology, Sinsheimer Laboratories, University of California, Santa Cruz, California 95064, USA

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Eva Hrabeta-Robinson Department of Molecular, Cell and Developmental Biology, Sinsheimer Laboratories, University of California, Santa Cruz, California 95064, USA

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Jennifer Compton Department of Molecular, Cell and Developmental Biology, Sinsheimer Laboratories, University of California, Santa Cruz, California 95064, USA

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& Virshup DM 2005 Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation. Molecular and Cellular Biology 25 2795 –2807. El Khissiin A & Leclercq G 1999 Implication of

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06725
Volume/Issue:
Volume 190: Issue 2
Free access
Eduardo Esteban-Zubero Department of Pharmacology and Physiology, University of Zaragoza, Zaragoza, Spain

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Francisco Agustín García-Gil Department of Surgery, Gynaecology and Obstetrics, University of Zaragoza, Zaragoza, Spain

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Laura López-Pingarrón Department of Medicine, Psychiatry and Dermatology, University of Zaragoza, Zaragoza, Spain

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Moisés Alejandro Alatorre-Jiménez Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA

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Pablo Iñigo-Gil Department of Medicine, Psychiatry and Dermatology, University of Zaragoza, Zaragoza, Spain

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Dun-Xian Tan Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA

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José Joaquín García Department of Pharmacology and Physiology, University of Zaragoza, Zaragoza, Spain

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Russel J Reiter Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA

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caspase-3. In addition, a significant reduction in the histological damage of renal tubules was apparent. Another problem observed after kidney transplan­tation is the disturbance in circadian rhythms and sleep–wake cycles including poor sleep quality

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-16-0117
Volume/Issue:
Volume 229: Issue 3
Free access
Marian Joëls Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands
University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

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– 192 ( https://doi.org/10.1159/000101917 ) 17446698 10.1159/000101917 Qian X Droste SK Lightman SL Reul JM Linthorst AC 2012 Circadian and ultradian rhythms of free glucocorticoid hormone are highly synchronized between the blood, the

Article Type:
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DOI:
https://doi.org/10.1530/JOE-18-0226
Volume/Issue:
Volume 238: Issue 3
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Maria Tsachaki Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland

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Arne Meyer Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland
AstraZeneca AG, Zug, Switzerland

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Benjamin Weger Karlsruhe Institute of Technology (KIT), Institute of Toxicology and Genetics, Eggenstein-Leopoldshafen, Germany
Nestlé Institute of Health Sciences SA, EPFL Innovation Park, Lausanne, Switzerland

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Denise V Kratschmar Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland

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Janina Tokarz Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Experimental Genetics, Genome Analysis Center, Neuherberg, Germany

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Jerzy Adamski Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Experimental Genetics, Genome Analysis Center, Neuherberg, Germany

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Heinz-Georg Belting Biozentrum, University of Basel, Basel, Switzerland

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Markus Affolter Biozentrum, University of Basel, Basel, Switzerland

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Thomas Dickmeis Karlsruhe Institute of Technology (KIT), Institute of Toxicology and Genetics, Eggenstein-Leopoldshafen, Germany

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Alex Odermatt Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland

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are produced in a circadian rhythm, and their levels highly increase under stress to maintain homeostasis. The stress response pathway is under the control of the hypothalamus–pituitary–adrenal (HPA) axis in human and the functionally equivalent

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-16-0495
Volume/Issue:
Volume 232: Issue 2
Free access