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Gareth Leng Centre for Integrative Physiology, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh EH9 8XD, UK

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Rafael Pineda Centre for Integrative Physiology, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh EH9 8XD, UK

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Nancy Sabatier Centre for Integrative Physiology, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh EH9 8XD, UK

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Mike Ludwig Centre for Integrative Physiology, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh EH9 8XD, UK

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-dependent behaviours. Nature Reviews Neuroscience 7 126–136. Copyright 2006, Rights Managed by Nature Publishing Group. (D) Under normal conditions, dendritic peptide release is not activated by electrical (spike) activity. This is indicated by the lack of

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Gilvanildo Roberto da Silva Department of Pathology, Federal University of Pernambuco, Recife, Brazil
Agrarian Sector, Federal University of Paraná, Veterinary Hospital, Curitiba, Brazil

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Mariane Gomes Carneiro Department of Pathology, Federal University of Pernambuco, Recife, Brazil

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Miriam Pereira Barbosa Department of Biomedicine, Federal University of Pernambuco, Recife, Brazil

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Jaciane de Almeida Costa Department of Pathology, Federal University of Pernambuco, Recife, Brazil

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Ivone Antonia de Souza Department of Pharmacology, Federal University of Pernambuco, Recife, Brazil

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Lisiane dos Santos Oliveira Academic Center of Vitória de Santo Antão, Federal University of Pernambuco, Recife, Brazil

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Diogo Antonio Alves de Vasconcelos Department of Nutrition, Federal University of Pernambuco, Recife, Brazil

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Elizabeth do Nascimento Department of Nutrition, Federal University of Pernambuco, Recife, Brazil

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Rhowena Jane Barbosa Matos Health Sciences Center, Federal University of Reconcavo da Bahia, Cruz das Almas, Brazil

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Sandra Lopes de Souza Department of Anatomy, Federal University of Pernambuco, Recife, Brazil

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Manuela Figueiroa Lyra de Freitas Department of Pathology, Federal University of Pernambuco, Recife, Brazil
Department of Anatomy, Federal University of Pernambuco, Recife, Brazil

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.86 ) 12105285 Baldwin AE Sadeghian K Kelley AE 2002 Appetitive instrumental learning requires coincident activation of NMDA and dopamine D 1 receptors within the medial prefrontal cortex . Journal of Neuroscience 22 1063 – 1071 . ( https://doi.org/10

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Zachary Silver Department of Neuroscience, Carleton University, Ottawa, Ontario, Canada

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Sam Abbott-Tate Department of Neuroscience, Carleton University, Ottawa, Ontario, Canada

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Lindsay Hyland Department of Neuroscience, Carleton University, Ottawa, Ontario, Canada

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Frances Sherratt Department of Neuroscience, Carleton University, Ottawa, Ontario, Canada

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Barbara Woodside Department of Neuroscience, Carleton University, Ottawa, Ontario, Canada

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Alfonso Abizaid Department of Neuroscience, Carleton University, Ottawa, Ontario, Canada

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endocannabinoid signaling in mice . Neuroscience 204 83 – 89 . ( https://doi.org/10.1016/j.neuroscience.2011.08.048 ) Brummelte S Galea LAM 2010 Chronic corticosterone during pregnancy and postpartum affects maternal care, cell proliferation and

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Eva Baquedano Department of Pediatrics, Department of Endocrinology, Centro de Investigación Biomédica en Red de fisiopatología de la obesidad y nutrición (CIBERobn), Universidad Autónoma de Madrid, Madrid, Spain
Department of Pediatrics, Department of Endocrinology, Centro de Investigación Biomédica en Red de fisiopatología de la obesidad y nutrición (CIBERobn), Universidad Autónoma de Madrid, Madrid, Spain

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Julie A Chowen Department of Pediatrics, Department of Endocrinology, Centro de Investigación Biomédica en Red de fisiopatología de la obesidad y nutrición (CIBERobn), Universidad Autónoma de Madrid, Madrid, Spain
Department of Pediatrics, Department of Endocrinology, Centro de Investigación Biomédica en Red de fisiopatología de la obesidad y nutrición (CIBERobn), Universidad Autónoma de Madrid, Madrid, Spain

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Jesús Argente Department of Pediatrics, Department of Endocrinology, Centro de Investigación Biomédica en Red de fisiopatología de la obesidad y nutrición (CIBERobn), Universidad Autónoma de Madrid, Madrid, Spain
Department of Pediatrics, Department of Endocrinology, Centro de Investigación Biomédica en Red de fisiopatología de la obesidad y nutrición (CIBERobn), Universidad Autónoma de Madrid, Madrid, Spain
Department of Pediatrics, Department of Endocrinology, Centro de Investigación Biomédica en Red de fisiopatología de la obesidad y nutrición (CIBERobn), Universidad Autónoma de Madrid, Madrid, Spain

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Laura M Frago Department of Pediatrics, Department of Endocrinology, Centro de Investigación Biomédica en Red de fisiopatología de la obesidad y nutrición (CIBERobn), Universidad Autónoma de Madrid, Madrid, Spain
Department of Pediatrics, Department of Endocrinology, Centro de Investigación Biomédica en Red de fisiopatología de la obesidad y nutrición (CIBERobn), Universidad Autónoma de Madrid, Madrid, Spain

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. References Åberg MA Åberg ND Hedbäcker H Oscarsson J Eriksson PS 2000 Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus . Journal of Neuroscience 20 2896 – 2903

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Hyunju Chung
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Endan Li Department of Core Research Laboratory, Department of Pharmacology and Medical Research Center for Bioreaction to ROS and Biomedical Science Institute, Clinical Research Institute, Kyung Hee University Hospital at Gangdong, Seoul, Korea

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Yumi Kim Department of Core Research Laboratory, Department of Pharmacology and Medical Research Center for Bioreaction to ROS and Biomedical Science Institute, Clinical Research Institute, Kyung Hee University Hospital at Gangdong, Seoul, Korea

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Sehee Kim Department of Core Research Laboratory, Department of Pharmacology and Medical Research Center for Bioreaction to ROS and Biomedical Science Institute, Clinical Research Institute, Kyung Hee University Hospital at Gangdong, Seoul, Korea

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Seungjoon Park Department of Core Research Laboratory, Department of Pharmacology and Medical Research Center for Bioreaction to ROS and Biomedical Science Institute, Clinical Research Institute, Kyung Hee University Hospital at Gangdong, Seoul, Korea

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neurogenesis in the adult rat hippocampus . Journal of Neuroscience 20 2896 – 2903 . Abizaid A Liu ZW Andrews ZB Shanabrough M Borok E Elsworth JD Roth RH Sleeman MW Picciotto MR Tschop MH 2006 Ghrelin modulates the activity and

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Brenton T Laing Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA
East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, North Carolina, USA

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Khoa Do Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA
East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, North Carolina, USA

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Tomoko Matsubara Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA
East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, North Carolina, USA

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David W Wert East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, North Carolina, USA

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Michael J Avery Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA

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Erin M Langdon Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA

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Donghai Zheng Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA
East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, North Carolina, USA
Human Performance Laboratory, Collage of Human Performance and Health, East Carolina University, Greenville, North Carolina, USA

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Hu Huang Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA
East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, North Carolina, USA
Human Performance Laboratory, Collage of Human Performance and Health, East Carolina University, Greenville, North Carolina, USA
Department of Physiology, East Carolina University, Greenville, North Carolina, USA

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: relationship between agouti-related protein and proopiomelanocortin in the brain . Journal of Neuroscience 26 1 – 7 . Balthasar N Coppari R McMinn J Liu SM Lee CE Tang V Kenny CD McGovern RA Chua SC Jr Elmquist JK

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Alberto Loizzo
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Santi M Spampinato Department of Therapeutic Research and Medicines Evaluation, Department of Pharmacology, Department of Pharmaceutical and Biomedical Sciences, Department of Psychiatry, Department of Psychology, Istituto Superiore di Sanita', via Regina Elena 299, 00161 Rome, Italy

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Gabriele Campana Department of Therapeutic Research and Medicines Evaluation, Department of Pharmacology, Department of Pharmaceutical and Biomedical Sciences, Department of Psychiatry, Department of Psychology, Istituto Superiore di Sanita', via Regina Elena 299, 00161 Rome, Italy

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Stefano Vella
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Andrea Fortuna
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Loredana Costa
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Anna Capasso Department of Therapeutic Research and Medicines Evaluation, Department of Pharmacology, Department of Pharmaceutical and Biomedical Sciences, Department of Psychiatry, Department of Psychology, Istituto Superiore di Sanita', via Regina Elena 299, 00161 Rome, Italy

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Palmiero Monteleone Department of Therapeutic Research and Medicines Evaluation, Department of Pharmacology, Department of Pharmaceutical and Biomedical Sciences, Department of Psychiatry, Department of Psychology, Istituto Superiore di Sanita', via Regina Elena 299, 00161 Rome, Italy

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Paolo Renzi Department of Therapeutic Research and Medicines Evaluation, Department of Pharmacology, Department of Pharmaceutical and Biomedical Sciences, Department of Psychiatry, Department of Psychology, Istituto Superiore di Sanita', via Regina Elena 299, 00161 Rome, Italy

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Stefano Loizzo
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LTP . Journal of Neuroscience 26 3951 – 3958 . ( doi:10.1523/JNEUROSCI.4901-05.2006 ) Akil HA & Morano MI 1995 Stress. In Psychopharmacology: The Fourth Generation of Progress , pp 773–785. Eds FE Bloom & DJ Kupfer. New York: Raven Press, Ltd

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Yan Zhou Laboratory of the Biology of Addictive Diseases, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA

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Jacob Bendor Laboratory of the Biology of Addictive Diseases, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA

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Lauren Hofmann Laboratory of the Biology of Addictive Diseases, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA

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Matthew Randesi Laboratory of the Biology of Addictive Diseases, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA

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Ann Ho Laboratory of the Biology of Addictive Diseases, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA

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Mary Jeanne Kreek Laboratory of the Biology of Addictive Diseases, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA

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TC , Lee CE, Lu J, Elmquist JK, Hara J, Willie JT, Beuchmann CT, Chemelli RM, Sakurai T, Yanagisawa M et al. 2001 Orexin (hypocretin) neurons contain dynorphin. Journal of Neuroscience 21 RC168 1 –6. Culpepper

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Iyad H Manaserh Department of Physiology and Pharmacology, College of Medicine and Life Sciences, The University of Toledo, Toledo, Ohio, USA
Center for Diabetes and Endocrine Research, College of Medicine and Life Sciences, The University of Toledo, Toledo, Ohio, USA

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Emily Maly Department of Physiology and Pharmacology, College of Medicine and Life Sciences, The University of Toledo, Toledo, Ohio, USA

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Marziyeh Jahromi Department of Physiology and Pharmacology, College of Medicine and Life Sciences, The University of Toledo, Toledo, Ohio, USA

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Lakshmikanth Chikkamenahalli Department of Physiology and Pharmacology, College of Medicine and Life Sciences, The University of Toledo, Toledo, Ohio, USA

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Joshua Park Department of Neuroscience, College of Medicine and Life Sciences, The University of Toledo, Toledo, Ohio, USA

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Jennifer Hill Department of Physiology and Pharmacology, College of Medicine and Life Sciences, The University of Toledo, Toledo, Ohio, USA
Center for Diabetes and Endocrine Research, College of Medicine and Life Sciences, The University of Toledo, Toledo, Ohio, USA

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partner . Trends in Neurosciences 22 208 – 215 . ( https://doi.org/10.1016/s0166-2236(98)01349-6 ) Bamshad M Aoki VT Adkison MG Warren WS Bartness TJ 1998 Central nervous system origins of the sympathetic nervous system outflow to

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Patricia Joseph-Bravo Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México (UNAM), A.P. 510-3, Cuernavaca, Morelos 62250, Mexico

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Lorraine Jaimes-Hoy Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México (UNAM), A.P. 510-3, Cuernavaca, Morelos 62250, Mexico

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Jean-Louis Charli Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México (UNAM), A.P. 510-3, Cuernavaca, Morelos 62250, Mexico

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Schilit A Lee FS 2013 Stress effects on BDNF expression: effects of age, sex, and form of stress . Neuroscience 239 149 – 156 . ( doi:10.1016/j.neuroscience.2013.01.074 ) Boler J Enzmann F Folkers K Bowers CY Schally AV 1969 The

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