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Yue Chen Department of Medicine, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia

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Jeffrey D Zajac Department of Medicine, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia

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Helen E MacLean Department of Medicine, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia

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2001 Characterization of 5′-regulatory region of human myostatin gene: regulation by dexamethasone in vitro . American Journal of Physiology – Endocrinology and Metabolism 281 E1128 –E1136. McNally EM 2004 Powerful

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David A Taylor-Fishwick Department of Medicine, Strelitz Diabetes Institutes, Eastern Virginia Medical School, Norfolk, Virginia 23510, USA
Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, Virginia 23510, USA
Department of Anatomy and Neurobiology, Eastern Virginia Medical School, Norfolk, Virginia 23510, USA

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Wenjing Shi Department of Medicine, Strelitz Diabetes Institutes, Eastern Virginia Medical School, Norfolk, Virginia 23510, USA
Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, Virginia 23510, USA
Department of Anatomy and Neurobiology, Eastern Virginia Medical School, Norfolk, Virginia 23510, USA

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Gary L Pittenger Department of Medicine, Strelitz Diabetes Institutes, Eastern Virginia Medical School, Norfolk, Virginia 23510, USA
Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, Virginia 23510, USA
Department of Anatomy and Neurobiology, Eastern Virginia Medical School, Norfolk, Virginia 23510, USA

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Aaron I Vinik Department of Medicine, Strelitz Diabetes Institutes, Eastern Virginia Medical School, Norfolk, Virginia 23510, USA
Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, Virginia 23510, USA
Department of Anatomy and Neurobiology, Eastern Virginia Medical School, Norfolk, Virginia 23510, USA

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induction of INGAP-promoter activity stimulated by LIF in control 293 cells. This stimulation was inhibited by 50% ( P < 0.05, t -test) in 293 cells expressing PDX-1 (Fig. 3B ). Thus the negative action of PDX-1 on INGAP gene regulation extends to both PMA

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Ana Fernanda Castillo Departamento de Bioquímica Humana, Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), Buenos Aires, Argentina

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Cecilia Poderoso Departamento de Bioquímica Humana, Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), Buenos Aires, Argentina

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Paula Mariana Maloberti Departamento de Bioquímica Humana, Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), Buenos Aires, Argentina

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Fabiana Cornejo Maciel Departamento de Bioquímica Humana, Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), Buenos Aires, Argentina

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María Mercedes Mori Sequeiros Garcia Departamento de Bioquímica Humana, Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), Buenos Aires, Argentina

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Ulises Daniel Orlando CONICET – Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), Buenos Aires, Argentina

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Pablo Mele Departamento de Bioquímica Humana, Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), Buenos Aires, Argentina

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Yanina Benzo Departamento de Bioquímica Humana, Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), Buenos Aires, Argentina

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Melina Andrea Dattilo Departamento de Bioquímica Humana, Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), Buenos Aires, Argentina

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Jesica Prada CONICET – Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), Buenos Aires, Argentina

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Luciano Quevedo CONICET – Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), Buenos Aires, Argentina

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Matías Belluno CONICET – Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), Buenos Aires, Argentina

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Cristina Paz Departamento de Bioquímica Humana, Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), Buenos Aires, Argentina

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Ernesto Jorge Podesta Departamento de Bioquímica Humana, Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), Buenos Aires, Argentina

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impaired phosphorylation by ERK reduces StAR affinity for cholesterol. Several mechanisms may underlie StAR expression mediated by MFN2. Although the direct role of MFN2 in STAR promoter or gene expression remains unknown, STAR gene regulation by

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Caroline C Faria Instituto de Biofísica Carlos Chagas Filho, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Leonardo Matta Pereira Instituto de Biofísica Carlos Chagas Filho, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Luiz Gabriel Portilho Moreira Instituto de Biofísica Carlos Chagas Filho, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Kathelinie Celestino Faustino Instituto de Biofísica Carlos Chagas Filho, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Milena Simões Peixoto Instituto de Biofísica Carlos Chagas Filho, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Ariclécio Cunha de Oliveira Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Ceará, Brazil

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Andrea Claudia Freitas Ferreira Instituto de Biofísica Carlos Chagas Filho, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
NUMPEX, Campus Duque de Caxias, UFRJ, Rio de Janeiro, Brazil

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Denise Pires Carvalho Instituto de Biofísica Carlos Chagas Filho, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Rodrigo Soares Fortunato Instituto de Biofísica Carlos Chagas Filho, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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contribute to the overall increase in total GPx enzyme activity. Discrepancies between mRNA levels and enzyme activities in other examined isoforms may be linked to diverse and not yet fully understood mechanisms of gene regulation for each isoform. Notably

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Maik Pietzner Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany
DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany

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Tim Kacprowski Chair of Experimental Bioinformatics, TUM School of Life Sciences Weihenstephan Technical University of Munich, Freising-Weihenstephan, Germany

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Nele Friedrich Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany
DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany

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GJ 2004 MicroRNAs: small RNAs with a big role in gene regulation . Nature Review Genetics 5 522 – 531 . ( https://doi.org/10.1038/nrg1379 ) 10.1038/nrg1379 Hine C Kim HJ Zhu Y Harputlugil E Longchamp A Matos MS Ramadoss P

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Elias Rawish Institute of Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, Lübeck, Germany
DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany
CBBM (Center of Brain, Behavior and Metabolism), Lübeck, Germany

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Laura Nickel Institute of Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, Lübeck, Germany
DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany
CBBM (Center of Brain, Behavior and Metabolism), Lübeck, Germany

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Franziska Schuster Institute of Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, Lübeck, Germany
CBBM (Center of Brain, Behavior and Metabolism), Lübeck, Germany

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Ines Stölting Institute of Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, Lübeck, Germany

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Alex Frydrychowicz Department of Radiology and Nuclear Medicine, University-Hospital Schleswig Holstein and University of Lübeck, Lübeck, Germany

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Kathrin Saar Max Delbruck Center for Molecular Medicine in the Helmholtz Association, Berlin-Buch, Germany
DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany

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Norbert Hübner Max Delbruck Center for Molecular Medicine in the Helmholtz Association, Berlin-Buch, Germany
DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany

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Alaa Othman CBBM (Center of Brain, Behavior and Metabolism), Lübeck, Germany
Institute for Clinical Chemistry, University Hospital Zürich, Zurich, Switzerland

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Lars Kuerschner Life and Medical Sciences Institute (LIMES), University of Bonn, Bonn, Germany

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Walter Raasch Institute of Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, Lübeck, Germany
DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany
CBBM (Center of Brain, Behavior and Metabolism), Lübeck, Germany

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is not associated with PPARgamma target gene regulation . Endocrinology 1103 – 1115 . ( https://doi.org/10.1210/en.2011-0183 ) Muller-Fielitz H Hubel N Mildner M Vogt FM Barkhausen J Raasch W 2014 Chronic blockade of angiotensin

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Antonella Rosario Ramona Cáceres Laboratorio de Fisiopatología Ovárica, Instituto de Medicina y Biología Experimental de Cuyo (IMBECU – CONICET Mendoza), Mendoza, Argentina
Facultad de Ingeniería y Facultad de Ciencias Médicas, Universidad de Mendoza, Mendoza, Argentina

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Fiorella Campo Verde Arboccó Laboratorio de Fisiopatología Ovárica, Instituto de Medicina y Biología Experimental de Cuyo (IMBECU – CONICET Mendoza), Mendoza, Argentina

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María de los Ángeles Sanhueza Laboratorio de Fisiopatología Ovárica, Instituto de Medicina y Biología Experimental de Cuyo (IMBECU – CONICET Mendoza), Mendoza, Argentina

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Daniela Alejandra Cardone Laboratorio de Fisiopatología Ovárica, Instituto de Medicina y Biología Experimental de Cuyo (IMBECU – CONICET Mendoza), Mendoza, Argentina

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Graciela Beatriz Rodriguez Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis, San Luis, Argentina

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Marilina Casais Laboratorio de Biología de la Reproducción (LABIR), Universidad Nacional de San Luis, San Luis, Argentina

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Adriana Soledad Vega Orozco Laboratorio de Biología de la Reproducción (LABIR), Universidad Nacional de San Luis, San Luis, Argentina

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Myriam Raquel Laconi Laboratorio de Fisiopatología Ovárica, Instituto de Medicina y Biología Experimental de Cuyo (IMBECU – CONICET Mendoza), Mendoza, Argentina
Facultad de Ingeniería y Facultad de Ciencias Médicas, Universidad de Mendoza, Mendoza, Argentina

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Journal of Endocrinology 133 375 – 380 . ( https://doi.org/10.1530/eje.0.1330375 ) George JW Dille EA & Heckert LL 2011 Current concepts of follicle-stimulating hormone receptor gene regulation . Biology of Reproduction 84 7 – 17 . ( https

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Cyril S Anyetei-Anum Department of Biology, College of William and Mary, Williamsburg, Virginia, USA

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Vincent R Roggero Department of Biology, College of William and Mary, Williamsburg, Virginia, USA

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Lizabeth A Allison Department of Biology, College of William and Mary, Williamsburg, Virginia, USA

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K Brent GA 2012 Thyroid hormone receptor isoform-specific modification by small ubiquitin-like modifier (SUMO) modulates thyroid hormone-dependent gene regulation . Journal of Biological Chemistry 287 36499 – 36508 . ( https://doi.org/10

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A J Forhead Department of Physiology, Department of Biological and Medical Sciences, Development and Neuroscience, University of Cambridge, Physiology Building, Downing Street, Cambridge CB2 3EG, UK
Department of Physiology, Department of Biological and Medical Sciences, Development and Neuroscience, University of Cambridge, Physiology Building, Downing Street, Cambridge CB2 3EG, UK

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A L Fowden Department of Physiology, Department of Biological and Medical Sciences, Development and Neuroscience, University of Cambridge, Physiology Building, Downing Street, Cambridge CB2 3EG, UK

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-0400 ) Charalambous M Hernandez A 2013 Genomic imprinting of the type 3 thyroid hormone deiodinase gene: regulation and developmental implications . Biochimica et Biophysica Acta 1830 3946 – 3955 . ( doi:10.1016/j.bbagen.2012.03.015 ) Chattergoon NN

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Kimberley C W Wang Early Origins of Adult Health Research Group, School of Pharmacy and Medical Sciences, Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia

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Kimberley J Botting Early Origins of Adult Health Research Group, School of Pharmacy and Medical Sciences, Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia

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Song Zhang Early Origins of Adult Health Research Group, School of Pharmacy and Medical Sciences, Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia

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I Caroline McMillen Early Origins of Adult Health Research Group, School of Pharmacy and Medical Sciences, Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia

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Doug A Brooks Mechanisms in Cell Biology and Disease Research Group, School of Pharmacy and Medical Sciences, Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia

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Janna L Morrison Early Origins of Adult Health Research Group, School of Pharmacy and Medical Sciences, Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia

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RL 2007 Epigenetic gene regulation: linking early developmental environment to adult disease . Reproductive Toxicology 23 297 – 307 . ( doi:10.1016/j.reprotox.2006.08.012 ) Domenighetti AA Wang Q Egger M Richards SM

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