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Carmen Corciulo
Carmen Corciulo
Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Julia M Scheffler
Julia M Scheffler
Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Piotr Humeniuk
Piotr Humeniuk
Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Alicia Del Carpio Pons
Alicia Del Carpio Pons
Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Alexandra Stubelius
Alexandra Stubelius
Division of Chemical Biology, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden
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Ula Von Mentzer
Ula Von Mentzer
Division of Chemical Biology, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden
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Christina Drevinge
Christina Drevinge
Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Aidan Barrett
Aidan Barrett
Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Sofia Wüstenhagen
Sofia Wüstenhagen
Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Matti Poutanen
Matti Poutanen
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, Turku Center for Disease Modeling, University of Turku, Turku, Finland
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Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, Turku Center for Disease Modeling, University of Turku, Turku, Finland
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Claes Ohlsson
Claes Ohlsson
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Department of Drug Treatment, Sahlgrenska University Hospital, Gothenburg, Sweden
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Department of Drug Treatment, Sahlgrenska University Hospital, Gothenburg, Sweden
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Marie K Lagerquist
Marie K Lagerquist
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Ulrika Islander
Ulrika Islander
Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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associated with structural subchondral bone damage, increased pain sensitivity also in body parts that are not directly affected by the disease, and mild inflammation of the synovium ( Loeser et al. 2012 ). OA affects more than 240 million people globally
Andrea Lovdel
Andrea Lovdel
University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK
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Karla J Suchacki
Karla J Suchacki
University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK
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Fiona Roberts
Fiona Roberts
University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK
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Richard J Sulston
Richard J Sulston
University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK
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Robert J Wallace
Robert J Wallace
Department of Orthopaedics, The University of Edinburgh, Edinburgh, UK
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Benjamin J Thomas
Benjamin J Thomas
University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK
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Rachel M B Bell
Rachel M B Bell
University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK
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Iris Pruñonosa Cervera
Iris Pruñonosa Cervera
University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK
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Gavin J Macpherson
Gavin J Macpherson
Department of Orthopaedic Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK
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Nicholas M Morton
Nicholas M Morton
University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK
Centre for Systems Health and Integrated Metabolic Research, Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham, UK
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Centre for Systems Health and Integrated Metabolic Research, Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham, UK
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Natalie Z M Homer
Natalie Z M Homer
University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK
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Karen E Chapman
Karen E Chapman
University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK
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William P Cawthorn
William P Cawthorn
University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK
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Introduction Bone marrow adipocytes comprise up to 70% of total bone marrow (BM) volume and over 10% of total adipose mass in healthy adult humans, collectively forming an integrated tissue referred to as bone marrow adipose tissue (BMAT
Lucia Zhang
Lucia Zhang
Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
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Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
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Kathy K Lee
Kathy K Lee
Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
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Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
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Kim S Sugamori
Kim S Sugamori
Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada
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Marc D Grynpas
Marc D Grynpas
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
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Jane Mitchell
Jane Mitchell
Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada
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Introduction Parathyroid hormone (PTH) is released in response to low levels of serum calcium and plays an essential role in the maintenance of extracellular calcium homeostasis and does so, in part, through its modulation of bone remodelling
Karin L Gustafsson
Karin L Gustafsson
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
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Sofia Movérare-Skrtic
Sofia Movérare-Skrtic
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
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Helen H Farman
Helen H Farman
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
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Cecilia Engdahl
Cecilia Engdahl
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
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Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
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Petra Henning
Petra Henning
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
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Karin H Nilsson
Karin H Nilsson
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
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Julia M Scheffler
Julia M Scheffler
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
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Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
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Edina Sehic
Edina Sehic
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
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Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
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Ulrika Islander
Ulrika Islander
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
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Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
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Ellis Levin
Ellis Levin
Division of Endocrinology, Department of Medicine, University of California, Irvine, Irvine, California, USA
Department of Veterans Affairs Medical Center, Long Beach, Long Beach, California, USA
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Department of Veterans Affairs Medical Center, Long Beach, Long Beach, California, USA
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Claes Ohlsson
Claes Ohlsson
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Department of Drug Treatment, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden
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Department of Drug Treatment, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden
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Marie K Lagerquist
Marie K Lagerquist
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
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-generation SERMs, have agonistic effects in bone and can prevent both vertebral and non-vertebral fractures in humans ( Cummings et al. 2010 , Silverman et al. 2012 ). Animal studies have also shown positive effects of these SERMs at both vertebral and non
Chalida Nakalekha
Chalida Nakalekha
Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
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Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
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Chieko Yokoyama
Chieko Yokoyama
Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
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Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
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Hiroyuki Miura
Hiroyuki Miura
Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
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Neil Alles
Neil Alles
Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
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Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
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Kazuhiro Aoki
Kazuhiro Aoki
Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
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Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
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Keiichi Ohya
Keiichi Ohya
Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
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Ikuo Morita
Ikuo Morita
Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
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Departments of, Cellular Physiological Chemistry, Fixed Prosthodontics, International Research Center for Molecular Science in Tooth and Bone Diseases (Global COE program), Institute of Cellular and System Medicine, Department of Hard Tissue Engineering (Pharmacology), Graduate School
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Introduction Prostaglandins (PGs) are one of the regulatory factors that affect bone metabolism ( Raisz 1995 , 1999 , Harada & Rodan 2003 ). They are produced by the sequential oxygenation of arachidonic acid by cyclooxygenases (COXs) and terminal
Hong Liu
Hong Liu
Institute of Dental Research, The Research Center for Bone and Stem Cells, Department of Medicine, Stomatological College
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Jian Guo
Jian Guo
Institute of Dental Research, The Research Center for Bone and Stem Cells, Department of Medicine, Stomatological College
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Lin Wang
Lin Wang
Institute of Dental Research, The Research Center for Bone and Stem Cells, Department of Medicine, Stomatological College
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Ning Chen
Ning Chen
Institute of Dental Research, The Research Center for Bone and Stem Cells, Department of Medicine, Stomatological College
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Andrew Karaplis
Andrew Karaplis
Institute of Dental Research, The Research Center for Bone and Stem Cells, Department of Medicine, Stomatological College
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David Goltzman
David Goltzman
Institute of Dental Research, The Research Center for Bone and Stem Cells, Department of Medicine, Stomatological College
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Dengshun Miao
Dengshun Miao
Institute of Dental Research, The Research Center for Bone and Stem Cells, Department of Medicine, Stomatological College
Institute of Dental Research, The Research Center for Bone and Stem Cells, Department of Medicine, Stomatological College
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Institute of Dental Research, The Research Center for Bone and Stem Cells, Department of Medicine, Stomatological College
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occurring in the 1α(OH)ase −/− mice on the normal diet was responsible for the increased bone formation. Moreover, the bone volume of the normocalcemic 1α(OH)ase −/− mice on the rescue diet was less than that observed in the wild-type mice, suggesting that
Richard Eastell
Richard Eastell
Academic Unit of Bone Metabolism, Division of Clinical Sciences (North), School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield, UK
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Introduction The decrease in the levels of oestrogen at the time of the menopause results in an increase in the rate of bone remodelling and this plays a major role in the development of postmenopausal osteoporosis. These changes are
S A Lanham
S A Lanham
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A L Fowden
A L Fowden
Bone and Joint Research Group, Department of Physiology, Institute of Developmental Sciences, University of Southampton School of Medicine, Tremona Road, Southampton SO16 6YD, UK
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C Roberts
C Roberts
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C Cooper
C Cooper
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R O C Oreffo
R O C Oreffo
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A J Forhead
A J Forhead
Bone and Joint Research Group, Department of Physiology, Institute of Developmental Sciences, University of Southampton School of Medicine, Tremona Road, Southampton SO16 6YD, UK
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Introduction Thyroid hormones play an important role in normal skeletal growth and development both before and after birth ( Williams 2009 ). In postnatal animals, triiodothyronine (T 3 ) stimulates bone growth and ossification by a number of
Guillaume Mabilleau
Guillaume Mabilleau
Groupe d’Etudes Remodelage Osseux et bioMatériaux, GEROM, SFR 42-08, Université d’Angers, IRIS-IBS Institut de Biologie en Santé, CHU d’Angers, Angers Cedex, France
Bone Pathology Unit, Angers University Hospital, Angers Cedex, France
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Bone Pathology Unit, Angers University Hospital, Angers Cedex, France
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Benoit Gobron
Benoit Gobron
Groupe d’Etudes Remodelage Osseux et bioMatériaux, GEROM, SFR 42-08, Université d’Angers, IRIS-IBS Institut de Biologie en Santé, CHU d’Angers, Angers Cedex, France
Rheumatology Department, Angers University Hospital, Angers Cedex, France
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Rheumatology Department, Angers University Hospital, Angers Cedex, France
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Aleksandra Mieczkowska
Aleksandra Mieczkowska
Groupe d’Etudes Remodelage Osseux et bioMatériaux, GEROM, SFR 42-08, Université d’Angers, IRIS-IBS Institut de Biologie en Santé, CHU d’Angers, Angers Cedex, France
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Rodolphe Perrot
Rodolphe Perrot
Service Commun d’Imageries et d’Analyses Microscopiques, SCIAM, SFR 42-08, Université d’Angers, IRIS-IBS Institut de Biologie en Santé, CHU d’Angers, Angers Cedex, France
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Daniel Chappard
Daniel Chappard
Groupe d’Etudes Remodelage Osseux et bioMatériaux, GEROM, SFR 42-08, Université d’Angers, IRIS-IBS Institut de Biologie en Santé, CHU d’Angers, Angers Cedex, France
Bone Pathology Unit, Angers University Hospital, Angers Cedex, France
Service Commun d’Imageries et d’Analyses Microscopiques, SCIAM, SFR 42-08, Université d’Angers, IRIS-IBS Institut de Biologie en Santé, CHU d’Angers, Angers Cedex, France
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Bone Pathology Unit, Angers University Hospital, Angers Cedex, France
Service Commun d’Imageries et d’Analyses Microscopiques, SCIAM, SFR 42-08, Université d’Angers, IRIS-IBS Institut de Biologie en Santé, CHU d’Angers, Angers Cedex, France
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Introduction Some evidences have emerged recently that the gut, and more specifically entero-endocrine cells, may play a role in maintaining optimal bone quality and bone mass ( Henriksen et al. 2003 , Xie et al. 2005 , Tsukiyama et al
Nicholaos I Papachristou
Nicholaos I Papachristou
Department of Anatomy-Histology-Embryology, Unit of Bone and Soft Tissue Studies, University of Patras Medical School, Patras, Greece
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Harry C Blair
Harry C Blair
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Pittsburgh VA Medical Center, Pittsburgh, Pennsylvania, USA
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Pittsburgh VA Medical Center, Pittsburgh, Pennsylvania, USA
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Kyriakos E Kypreos
Kyriakos E Kypreos
Department of Pharmacology, University of Patras Medical School, Patras, Greece
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Dionysios J Papachristou
Dionysios J Papachristou
Department of Anatomy-Histology-Embryology, Unit of Bone and Soft Tissue Studies, University of Patras Medical School, Patras, Greece
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
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Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
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( Constantinou et al. 2015 ). Recently, we identified a novel role of HDL in the pathogenesis of degenerative and metabolic bone diseases using experimental mouse models ( Triantaphyllidou et al . 2013 , Blair et al . 2016 a ), suggesting that low and
