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Key Laboratory of Molecular Epigenetics of Ministry of Education, Northeast Normal University, Changchun, Jilin, China
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Key Laboratory of Molecular Epigenetics of Ministry of Education, Northeast Normal University, Changchun, Jilin, China
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Key Laboratory of Molecular Epigenetics of Ministry of Education, Northeast Normal University, Changchun, Jilin, China
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and involution ( Macias & Hinck 2012 ). Mammary gland development requires hormones including prolactin (PRL), progesterone (P4) and estrogen (E2). PRL controls alveologenesis and lactogenesis of mammary gland through phosphorylation of JAK2/STAT5 axis
Centro de Microscopia Electrónica, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina
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Centro de Microscopia Electrónica, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina
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Centro de Microscopia Electrónica, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina
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Centro de Microscopia Electrónica, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina
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frequent type observed in the clinic (40%) and are characterised by the hypersecretion of prolactin (PRL). The next most common PitNETs are somatotrophinomas, which secrete growth hormone (GH) ( Ciccarelli et al. 2005 , Tritos & Miller 2023 ). The
Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, 2010 Sydney, Australia
University of Waikato, Hamilton 2020, New Zealand
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Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, 2010 Sydney, Australia
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Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, 2010 Sydney, Australia
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Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, 2010 Sydney, Australia
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Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, 2010 Sydney, Australia
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Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, 2010 Sydney, Australia
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Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, 2010 Sydney, Australia
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& Rosenfield 2003 ), including the pituitary hormone prolactin. Prolactin receptors (PRLR) have been localised to hair follicles ( Craven et al. 2001 ) and expression of mRNAs encoding one long (PRLRL) and two short forms of the receptor (PRLRS2 and PRLRS3
National Hormone and Peptide Program, Harbor-UCLA Medical Center, Torrence, California 90509, USA
Eppley Institute for Research in Cancer and Allied Diseases and the Department of Pathology and Microbiology, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, Nebraska 68198, USA
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National Hormone and Peptide Program, Harbor-UCLA Medical Center, Torrence, California 90509, USA
Eppley Institute for Research in Cancer and Allied Diseases and the Department of Pathology and Microbiology, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, Nebraska 68198, USA
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National Hormone and Peptide Program, Harbor-UCLA Medical Center, Torrence, California 90509, USA
Eppley Institute for Research in Cancer and Allied Diseases and the Department of Pathology and Microbiology, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, Nebraska 68198, USA
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National Hormone and Peptide Program, Harbor-UCLA Medical Center, Torrence, California 90509, USA
Eppley Institute for Research in Cancer and Allied Diseases and the Department of Pathology and Microbiology, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, Nebraska 68198, USA
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National Hormone and Peptide Program, Harbor-UCLA Medical Center, Torrence, California 90509, USA
Eppley Institute for Research in Cancer and Allied Diseases and the Department of Pathology and Microbiology, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, Nebraska 68198, USA
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National Hormone and Peptide Program, Harbor-UCLA Medical Center, Torrence, California 90509, USA
Eppley Institute for Research in Cancer and Allied Diseases and the Department of Pathology and Microbiology, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, Nebraska 68198, USA
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National Hormone and Peptide Program, Harbor-UCLA Medical Center, Torrence, California 90509, USA
Eppley Institute for Research in Cancer and Allied Diseases and the Department of Pathology and Microbiology, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, Nebraska 68198, USA
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Introduction Growth and differentiation of breast cancer is regulated by hormones, notably estrogen, progesterone and prolactin. In rodents, prolactin is a well-documented tumor promoter of the mammary gland, as revealed by a variety
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vehicle (Ethanol, 1 μM) were used as controls. After experimental treatments, medium was collected and stored at −70°C until rat prolactin radioimmunoassays (rPRL RIA) were performed. Rat prolactin radioimmunoassay (rPRL RIA) PRL levels were
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Introduction Prolactin is a protein hormone found in the pituitary gland of most vertebrates, which in mammals plays a central role in the regulation of mammary growth and lactation. In most mammals, prolactin is encoded by a single gene, but
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Inserm, APHP, Unit 845, Research Center Growth and Signaling, University Paris Descartes, Faculty of Medicine, Necker site, Paris 75015, France
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Classical view Prolactin (PRL) was discovered 80 years ago ( Stricker & Grueter 1928 , Riddle et al . 1933 ). In Endocrinology textbooks, PRL is defined as a pituitary-secreted polypeptide hormone which was named for its stimulatory action on
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Departments of, Vascular Medicine, Medical Biochemistry, Pathology, Experimental Immunology, INSERM, Department of Internal Medicine, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands
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. 2009 ). Whether prolactin is involved in the pathogenesis of human atherosclerosis and its atherothrombotic complications is currently the focus of our research ( Reuwer et al . 2009 a , b ). Recent observations suggest that prolactin, either in excess
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Hawaii Institute of Marine Biology, Department of Molecular Biosciences and Bioengineering, Department of Biology and Center for Neuroendocrine Studies, University of Hawaii, Kaneohe, Hawaii 96744, USA
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Hawaii Institute of Marine Biology, Department of Molecular Biosciences and Bioengineering, Department of Biology and Center for Neuroendocrine Studies, University of Hawaii, Kaneohe, Hawaii 96744, USA
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Hawaii Institute of Marine Biology, Department of Molecular Biosciences and Bioengineering, Department of Biology and Center for Neuroendocrine Studies, University of Hawaii, Kaneohe, Hawaii 96744, USA
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Introduction A necessary component of the systems that direct osmoregulatory processes are osmoreceptors that detect deviations from salt and water balance and initiate adaptive responses to restore equilibrium. The prolactin (Prl)-secreting cells
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anti-atherogenic therapies. Recent clinical evidence has identified the pituitary-derived hormone prolactin as a potential novel target to treat patients at risk of cardiovascular disease. Hyperprolactinemic subjects harboring a prolactin