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Hypothalamic Integration Mechanisms, Netherlands Institute for Neuroscience, Amsterdam, The Netherlands
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden, The Netherlands
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden, The Netherlands
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden, The Netherlands
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden, The Netherlands
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Department of Vascular Medicine, Amsterdam Diabetes Centre, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
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Hypothalamic Integration Mechanisms, Netherlands Institute for Neuroscience, Amsterdam, The Netherlands
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden, The Netherlands
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden, The Netherlands
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-described effects of BAs in lipid and carbohydrate metabolism, we hypothesized that central effects of BA contribute to the regulation of energy metabolism. Therefore, the aim of the present study was to determine the effects of central bile acid signaling on
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selectivity and tissue expression pattern give rise to the functional specificity of FGF19 and FGF21 (Yang et al. 2012) . Based on these findings, many investigators have concluded that FGF19 is primarily involved in the regulation of bile acid metabolism
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kit (Wiener Lab, Argentina), as described previously ( Chow et al . 2011 ). Hepatic lipid metabolism The mRNA expression of acetyl-CoA carboxylase (ACC) 1 and 2 ( Acaca and Acacb , respectively), fatty acid synthase ( Fas ), stearoyl
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development and maturation . Trends in Endocrinology and Metabolism 21 729 – 738 . ( doi:10.1016/j.tem.2010.09.001 ) Sharma S Chhibber S Mohan H 2013 Dietary supplementation with ω-3 polyunsaturated fatty acids ameliorates acute pneumonia
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Departments of, Child Health Care, General Surgery, Institute of Pediatric Research, Department of Public Health and Clinical Medicine, Nanjing Children's Hospital, Nanjing Medical University, 72 Guangzhou Road, Nanjing 210008, People's Republic of China
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). Taken together, these observations strongly suggest the existence of an association between local GC metabolism and nutritional status or fatty acid composition. In this study, we investigated the effects of three diets with different fatty acid
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.098 61.06 Downregulated pathways Fatty acid metabolism 4 <0.001 0.00 PPAR signaling pathway 4 <0.001 0.00 Retinol metabolism 2 0.047 30.06 Arachidonic acid metabolism 2 0.057 35
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. Journal of Biological Chemistry 277 34182 – 34190 . ( https://doi.org/10.1074/jbc.M204887200 ) 10.1074/jbc.M204887200 Harris WS Hustvedt BE Hagen E Green MH Lu G Drevon CA 1997 N-3 fatty acids and chylomicron metabolism in the rat
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mediate the phenotype of HFD-LNS1 mice, we next analyzed the expression profiles of genes involved in lipid metabolism by RT-qPCR. HFD feeding resulted in increased expression of the genes involved in lipogenesis, including Srebp-1c , fatty acid synthase
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.2174/1573399810666140508121012 ) Wang T Fahrmann JF Lee H Li YJ Tripathi SC Yue C Zhang C Lifshitz V Song J Yuan Y 2018 JAK/STAT3-regulated fatty acid β-oxidation is critical for breast cancer stem cell self-renewal and chemoresistance . Cell Metabolism 27 136