Filter

Refine by date

—

Refine by collections

Refine by access

  • Print
  • Save

Search Results

You are looking at 11 - 20 of 1,185 items for :

  • glucocorticoid x
  • Refine by access: All content x
Clear All
Bo He Department of Pharmacology, Wuhan University School of Basic Medical Sciences, Wuhan, China
School of Pharmaceutical Sciences and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, China

Search for other papers by Bo He in
Google Scholar
PubMed Close
,
Yinxian Wen Department of Orthopedic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China
Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan, China

Search for other papers by Yinxian Wen in
Google Scholar
PubMed Close
,
Shuwei Hu Department of Pharmacology, Wuhan University School of Basic Medical Sciences, Wuhan, China

Search for other papers by Shuwei Hu in
Google Scholar
PubMed Close
,
Guihua Wang Department of Pharmacology, Wuhan University School of Basic Medical Sciences, Wuhan, China

Search for other papers by Guihua Wang in
Google Scholar
PubMed Close
,
Wen Hu Department of Pharmacology, Wuhan University School of Basic Medical Sciences, Wuhan, China

Search for other papers by Wen Hu in
Google Scholar
PubMed Close
,
Jacques Magdalou UMR 7561 CNRS-Université de Lorraine, Faculté de Médicine, Vandoeuvre-lès-Nancy, Nancy, France

Search for other papers by Jacques Magdalou in
Google Scholar
PubMed Close
,
Liaobin Chen Department of Orthopedic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China
Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan, China

Search for other papers by Liaobin Chen in
Google Scholar
PubMed Close
, and
Hui Wang Department of Pharmacology, Wuhan University School of Basic Medical Sciences, Wuhan, China
Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan, China

Search for other papers by Hui Wang in
Google Scholar
PubMed Close

have demonstrated that PCE can lead to fetal overexposure to maternal glucocorticoids and hypothalamic-pituitary-adrenal (HPA) axis-associated neuroendocrine metabolic programming alterations, resulting in the increased susceptibility of adult offspring

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-19-0066
Volume/Issue:
Volume 242: Issue 3
Free access
Nathanael J Yates School of Human Sciences, The University of Western Australia, Perth, Australia

Search for other papers by Nathanael J Yates in
Google Scholar
PubMed Close
,
Dijana Tesic School of Human Sciences, The University of Western Australia, Perth, Australia

Search for other papers by Dijana Tesic in
Google Scholar
PubMed Close
,
Kirk W Feindel Centre for Microscopy, Characterisation and Analysis, The University of Western Australia, Perth, Australia

Search for other papers by Kirk W Feindel in
Google Scholar
PubMed Close
,
Jeremy T Smith School of Human Sciences, The University of Western Australia, Perth, Australia

Search for other papers by Jeremy T Smith in
Google Scholar
PubMed Close
,
Michael W Clarke Metabolomics Australia, Centre for Microscopy, Characterisation and Analysis, The University of Western Australia, Perth, Australia

Search for other papers by Michael W Clarke in
Google Scholar
PubMed Close
,
Celeste Wale School of Human Sciences, The University of Western Australia, Perth, Australia

Search for other papers by Celeste Wale in
Google Scholar
PubMed Close
,
Rachael C Crew School of Human Sciences, The University of Western Australia, Perth, Australia

Search for other papers by Rachael C Crew in
Google Scholar
PubMed Close
,
Michaela D Wharfe School of Human Sciences, The University of Western Australia, Perth, Australia

Search for other papers by Michaela D Wharfe in
Google Scholar
PubMed Close
,
Andrew J O Whitehouse Telethon Kids Institute, The University of Western Australia, Perth, Australia

Search for other papers by Andrew J O Whitehouse in
Google Scholar
PubMed Close
, and
Caitlin S Wyrwoll School of Human Sciences, The University of Western Australia, Perth, Australia

Search for other papers by Caitlin S Wyrwoll in
Google Scholar
PubMed Close

development and function likely means that vitamin D deficiency associates with many other neuropsychiatric outcomes. We have recently shown that vitamin D deficiency in mice increases placental glucocorticoid transfer and increases fetal brain

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0008
Volume/Issue:
Volume 237: Issue 2
Free access
Young Hoon Son Department of Biochemistry and Molecular Biology, Institute of Human–Environment Interface Biology, Department of Rehabilitation Medicine, Seoul National University College of Medicine, 103 Daehak‐ro, Jongno‐Gu, Seoul 110‐799, Korea

Search for other papers by Young Hoon Son in
Google Scholar
PubMed Close
,
Seok-Jin Lee Department of Biochemistry and Molecular Biology, Institute of Human–Environment Interface Biology, Department of Rehabilitation Medicine, Seoul National University College of Medicine, 103 Daehak‐ro, Jongno‐Gu, Seoul 110‐799, Korea

Search for other papers by Seok-Jin Lee in
Google Scholar
PubMed Close
,
Ki-Baek Lee Department of Biochemistry and Molecular Biology, Institute of Human–Environment Interface Biology, Department of Rehabilitation Medicine, Seoul National University College of Medicine, 103 Daehak‐ro, Jongno‐Gu, Seoul 110‐799, Korea

Search for other papers by Ki-Baek Lee in
Google Scholar
PubMed Close
,
Jin-Haeng Lee Department of Biochemistry and Molecular Biology, Institute of Human–Environment Interface Biology, Department of Rehabilitation Medicine, Seoul National University College of Medicine, 103 Daehak‐ro, Jongno‐Gu, Seoul 110‐799, Korea

Search for other papers by Jin-Haeng Lee in
Google Scholar
PubMed Close
,
Eui Man Jeong Department of Biochemistry and Molecular Biology, Institute of Human–Environment Interface Biology, Department of Rehabilitation Medicine, Seoul National University College of Medicine, 103 Daehak‐ro, Jongno‐Gu, Seoul 110‐799, Korea
Department of Biochemistry and Molecular Biology, Institute of Human–Environment Interface Biology, Department of Rehabilitation Medicine, Seoul National University College of Medicine, 103 Daehak‐ro, Jongno‐Gu, Seoul 110‐799, Korea

Search for other papers by Eui Man Jeong in
Google Scholar
PubMed Close
,
Sun Gun Chung Department of Biochemistry and Molecular Biology, Institute of Human–Environment Interface Biology, Department of Rehabilitation Medicine, Seoul National University College of Medicine, 103 Daehak‐ro, Jongno‐Gu, Seoul 110‐799, Korea

Search for other papers by Sun Gun Chung in
Google Scholar
PubMed Close
,
Sang-Chul Park Department of Biochemistry and Molecular Biology, Institute of Human–Environment Interface Biology, Department of Rehabilitation Medicine, Seoul National University College of Medicine, 103 Daehak‐ro, Jongno‐Gu, Seoul 110‐799, Korea

Search for other papers by Sang-Chul Park in
Google Scholar
PubMed Close
, and
In-Gyu Kim Department of Biochemistry and Molecular Biology, Institute of Human–Environment Interface Biology, Department of Rehabilitation Medicine, Seoul National University College of Medicine, 103 Daehak‐ro, Jongno‐Gu, Seoul 110‐799, Korea
Department of Biochemistry and Molecular Biology, Institute of Human–Environment Interface Biology, Department of Rehabilitation Medicine, Seoul National University College of Medicine, 103 Daehak‐ro, Jongno‐Gu, Seoul 110‐799, Korea

Search for other papers by In-Gyu Kim in
Google Scholar
PubMed Close

Introduction Glucocorticoids have diverse and tissue-specific effects on cellular metabolism. During metabolic stress, such as starvation, glucocorticoids promote degradation and suppress synthesis of muscle proteins in the skeletal muscle, thereby

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-14-0490
Volume/Issue:
Volume 225: Issue 1
Open access
Craig L Doig School of Clinical and Experimental Medicine, Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Birmingham B15 2TT, UK

Search for other papers by Craig L Doig in
Google Scholar
PubMed Close
,
Jamila Bashir School of Clinical and Experimental Medicine, Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Birmingham B15 2TT, UK

Search for other papers by Jamila Bashir in
Google Scholar
PubMed Close
,
Agnieszka E Zielinska School of Clinical and Experimental Medicine, Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Birmingham B15 2TT, UK

Search for other papers by Agnieszka E Zielinska in
Google Scholar
PubMed Close
,
Mark S Cooper School of Clinical and Experimental Medicine, Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Birmingham B15 2TT, UK

Search for other papers by Mark S Cooper in
Google Scholar
PubMed Close
,
Paul M Stewart School of Clinical and Experimental Medicine, Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Birmingham B15 2TT, UK

Search for other papers by Paul M Stewart in
Google Scholar
PubMed Close
, and
Gareth G Lavery School of Clinical and Experimental Medicine, Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Birmingham B15 2TT, UK

Search for other papers by Gareth G Lavery in
Google Scholar
PubMed Close

Introduction The endogenous glucocorticoid (GC) concentrations are determined by the activity of the hypothalamic–pituitary–adrenal axis, with tissue and intracellular exposure further augmented through the activity of the enzyme 11β

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0494
Volume/Issue:
Volume 220: Issue 3
Open access
Maria Tsachaki Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland

Search for other papers by Maria Tsachaki in
Google Scholar
PubMed Close
,
Arne Meyer Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland
AstraZeneca AG, Zug, Switzerland

Search for other papers by Arne Meyer in
Google Scholar
PubMed Close
,
Benjamin Weger Karlsruhe Institute of Technology (KIT), Institute of Toxicology and Genetics, Eggenstein-Leopoldshafen, Germany
Nestlé Institute of Health Sciences SA, EPFL Innovation Park, Lausanne, Switzerland

Search for other papers by Benjamin Weger in
Google Scholar
PubMed Close
,
Denise V Kratschmar Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland

Search for other papers by Denise V Kratschmar in
Google Scholar
PubMed Close
,
Janina Tokarz Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Experimental Genetics, Genome Analysis Center, Neuherberg, Germany

Search for other papers by Janina Tokarz in
Google Scholar
PubMed Close
,
Jerzy Adamski Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Experimental Genetics, Genome Analysis Center, Neuherberg, Germany

Search for other papers by Jerzy Adamski in
Google Scholar
PubMed Close
,
Heinz-Georg Belting Biozentrum, University of Basel, Basel, Switzerland

Search for other papers by Heinz-Georg Belting in
Google Scholar
PubMed Close
,
Markus Affolter Biozentrum, University of Basel, Basel, Switzerland

Search for other papers by Markus Affolter in
Google Scholar
PubMed Close
,
Thomas Dickmeis Karlsruhe Institute of Technology (KIT), Institute of Toxicology and Genetics, Eggenstein-Leopoldshafen, Germany

Search for other papers by Thomas Dickmeis in
Google Scholar
PubMed Close
, and
Alex Odermatt Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland

Search for other papers by Alex Odermatt in
Google Scholar
PubMed Close

of 11-oxy glucocorticoids and androgens in zebrafish compared to human. Glucocorticoids regulate a vast number of physiological functions, ranging from metabolism and development to immune system, neuronal and cardiovascular function. Glucocorticoids

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-16-0495
Volume/Issue:
Volume 232: Issue 2
Free access
Yolanda Diz-Chaves Laboratory of Endocrinology, Center for Biomedical Research – CINBIO, University of Vigo, Vigo, Spain
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain

Search for other papers by Yolanda Diz-Chaves in
Google Scholar
PubMed Close
,
Manuel Gil-Lozano Laboratory of Endocrinology, Center for Biomedical Research – CINBIO, University of Vigo, Vigo, Spain
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain

Search for other papers by Manuel Gil-Lozano in
Google Scholar
PubMed Close
,
Laura Toba Laboratory of Endocrinology, Center for Biomedical Research – CINBIO, University of Vigo, Vigo, Spain
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain

Search for other papers by Laura Toba in
Google Scholar
PubMed Close
,
Juan Fandiño Laboratory of Endocrinology, Center for Biomedical Research – CINBIO, University of Vigo, Vigo, Spain
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain

Search for other papers by Juan Fandiño in
Google Scholar
PubMed Close
,
Hugo Ogando Laboratory of Endocrinology, Center for Biomedical Research – CINBIO, University of Vigo, Vigo, Spain
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain

Search for other papers by Hugo Ogando in
Google Scholar
PubMed Close
,
Lucas C González-Matías Laboratory of Endocrinology, Center for Biomedical Research – CINBIO, University of Vigo, Vigo, Spain
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain

Search for other papers by Lucas C González-Matías in
Google Scholar
PubMed Close
, and
Federico Mallo Laboratory of Endocrinology, Center for Biomedical Research – CINBIO, University of Vigo, Vigo, Spain
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain

Search for other papers by Federico Mallo in
Google Scholar
PubMed Close

levels of glucocorticoids (GCs) and GC receptors (GC-Rs) in fat are markedly altered in obese subjects ( Pasquali et al. 2006 ). Indeed, the enzymes involved in GC synthesis are expressed distinctly in adipose tissues of obese subjects. The isoenzyme 11

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-16-0118
Volume/Issue:
Volume 230: Issue 2
Free access
Ken K Y Ho Centres for Health Research, Princess Alexandra Hospital, The University of Queensland and The Translation Research Institute, Brisbane, Queensland, Australia

Search for other papers by Ken K Y Ho in
Google Scholar
PubMed Close

thermometry (IRT) and indirect calorimetry to investigate the extent to which thermogenesis contributes to whole body energy production using glucocorticoids as a model of perturbed energy metabolism. Glucocorticoids and post-prandial energy

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-18-0240
Volume/Issue:
Volume 238: Issue 3
Free access
Zhenguang Zhang University/BHF Centre for Cardiovascular Science, The Queen’s Medical Research Institute, The University of Edinburgh, Edinburgh, UK

Search for other papers by Zhenguang Zhang in
Google Scholar
PubMed Close
,
Agnes E Coutinho University/BHF Centre for Cardiovascular Science, The Queen’s Medical Research Institute, The University of Edinburgh, Edinburgh, UK

Search for other papers by Agnes E Coutinho in
Google Scholar
PubMed Close
,
Tak Yung Man University/BHF Centre for Cardiovascular Science, The Queen’s Medical Research Institute, The University of Edinburgh, Edinburgh, UK

Search for other papers by Tak Yung Man in
Google Scholar
PubMed Close
,
Tiina M J Kipari Centre for Genomic and Experimental Medicine, MRC Institute of Genetic and Molecular Medicine, The University of Edinburgh, Western General Hospital, Edinburgh, UK

Search for other papers by Tiina M J Kipari in
Google Scholar
PubMed Close
,
Patrick W F Hadoke University/BHF Centre for Cardiovascular Science, The Queen’s Medical Research Institute, The University of Edinburgh, Edinburgh, UK

Search for other papers by Patrick W F Hadoke in
Google Scholar
PubMed Close
,
Donald M Salter Centre for Genomic and Experimental Medicine, MRC Institute of Genetic and Molecular Medicine, The University of Edinburgh, Western General Hospital, Edinburgh, UK

Search for other papers by Donald M Salter in
Google Scholar
PubMed Close
,
Jonathan R Seckl University/BHF Centre for Cardiovascular Science, The Queen’s Medical Research Institute, The University of Edinburgh, Edinburgh, UK

Search for other papers by Jonathan R Seckl in
Google Scholar
PubMed Close
, and
Karen E Chapman University/BHF Centre for Cardiovascular Science, The Queen’s Medical Research Institute, The University of Edinburgh, Edinburgh, UK

Search for other papers by Karen E Chapman in
Google Scholar
PubMed Close

Introduction Glucocorticoids exert anti-inflammatory effects both in vivo and in vitro . Whilst the potent effects of synthetic glucocorticoids have been widely exploited clinically to treat inflammatory disease, including rheumatoid

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-17-0223
Volume/Issue:
Volume 234: Issue 3
Open access
Anthony H Tsang Medical Department I, University of Lübeck, Lübeck, Germany

Search for other papers by Anthony H Tsang in
Google Scholar
PubMed Close
,
Mariana Astiz Medical Department I, University of Lübeck, Lübeck, Germany

Search for other papers by Mariana Astiz in
Google Scholar
PubMed Close
,
Maureen Friedrichs Medical Department I, University of Lübeck, Lübeck, Germany

Search for other papers by Maureen Friedrichs in
Google Scholar
PubMed Close
, and
Henrik Oster Medical Department I, University of Lübeck, Lübeck, Germany

Search for other papers by Henrik Oster in
Google Scholar
PubMed Close

circadian behaviors. SCN, suprachiasmatic nucleus; HPA, hypothalamic adrenocortical axis; MEL, melatonin; ACTH, adrenocorticotropic hormone; GC, glucocorticoid, FGF21, fibroblast growth factor. Molecular and anatomical makeup of the mammalian

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-16-0051
Volume/Issue:
Volume 230: Issue 1
Free access
Nan Li Department of Oncology & Metabolism, Medicine, School of
The Bateson Centre, Firth Court, Western Bank, Sheffield, UK

Search for other papers by Nan Li in
Google Scholar
PubMed Close
,
James A Oakes Department of Oncology & Metabolism, Medicine, School of
The Bateson Centre, Firth Court, Western Bank, Sheffield, UK

Search for other papers by James A Oakes in
Google Scholar
PubMed Close
,
Karl-Heinz Storbeck Department of Biochemistry, Stellenbosch University, Stellenbosch, Matieland, South Africa

Search for other papers by Karl-Heinz Storbeck in
Google Scholar
PubMed Close
,
Vincent T Cunliffe The Bateson Centre, Firth Court, Western Bank, Sheffield, UK
Department of Biomedical Science, Firth Court, Western Bank, Sheffield, UK

Search for other papers by Vincent T Cunliffe in
Google Scholar
PubMed Close
, and
Nils P Krone Department of Oncology & Metabolism, Medicine, School of
The Bateson Centre, Firth Court, Western Bank, Sheffield, UK
Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany

Search for other papers by Nils P Krone in
Google Scholar
PubMed Close

levels. In particular, molecular pathways controlling steroidogenesis and steroid signaling are highly conserved ( Lohr & Hammerschmidt 2011 , Tokarz et al. 2013 , 2015 ). Similar to humans, cortisol is the main glucocorticoid in zebrafish and is

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-19-0384
Volume/Issue:
Volume 244: Issue 2
Restricted access