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INSERM, Université Henri Poincaré, U954, Nutrition, Génétique et Exposition aux Risques Environnementaux, Faculté de Médecine, BP 184, F-54505 Vandoeuvre Cedex, France
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light period. Food was withdrawn during this 3-h period in order to ensure that all animals were in the same nutritional state. This time was also chosen in order to minimize interference with circadian hormonal rhythms as both ghrelin and leptin present
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INSERM U413, INSERM U567, Department of Endocrinology, Laboratory of Cellular and Molecular Neuroendocrinology, European Institute for Peptide Research (IFRMP 23), University of Rouen, 76821 Mont-Saint-Aignan, France
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-independent Cushing's syndrome was based on the results of hormonal investigations. Briefly, increase in 24-h urinary cortisol excretion, alteration of plasma cortisol circadian rhythm, lack of cortisol suppression under a low-dose dexamethasone test (2 mg/day for 2
Centre for Paediatrics and Child Health, Department of Paediatric Endocrinology, Department of Endocrinology, Centre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, M13 9WL, UK
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Centre for Paediatrics and Child Health, Department of Paediatric Endocrinology, Department of Endocrinology, Centre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, M13 9WL, UK
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Centre for Paediatrics and Child Health, Department of Paediatric Endocrinology, Department of Endocrinology, Centre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, M13 9WL, UK
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and females, defining ultradian rhythms of GH secretion (frequency <24 h). These studies were limited by the use of relatively insensitive GH immunoradiometric assays, in which up to 90% of the daytime GH samples were undetectable ( Plotnick et al
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and P 4 -treated rats was lower than pre-surge levels, there was no significant difference between the two groups. This decrease may represent an endogenous rhythm in TIDA neuronal activity that occurs on every day of the estrous cycle in female rats
Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Centre of Endocrinology Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Centre of Endocrinology Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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. ( https://doi.org/10.1210/jc.2014-3911 ) 25658017 Rao R Somvanshi P Klerman EB Marmar C Doyle 3rd FJ 2021 Modeling the influence of chronic sleep restriction on cortisol circadian rhythms, with implications for metabolic disorders
Pharmaceutical Sciences, New York State Center of Excellence in Bioinformatics and Life Sciences, Departments of
Pharmaceutical Sciences, New York State Center of Excellence in Bioinformatics and Life Sciences, Departments of
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Pharmaceutical Sciences, New York State Center of Excellence in Bioinformatics and Life Sciences, Departments of
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Pharmaceutical Sciences, New York State Center of Excellence in Bioinformatics and Life Sciences, Departments of
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with WKY rats. Because we only measured expression at one time within the 24-h cycle, we cannot determine whether the difference between GK and WKY reflects a disturbance in circadian rhythms in GK rats, which itself has been shown to contribute to
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Cano V 2008b Circadian rhythm drives the responsiveness of leptin-mediated hypothalamic pathway of cholecystokinin-8 . Neuroscience Letters 442 165 – 168 . ( https://doi.org/10.1016/j.neulet.2008.07.009 ) 10.1016/j.neulet.2008
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erythrocytes correlates well with the characterised rhythmicity of DHEAS and cortisol ( Goncharova et al . 2008 b ). Additionally, a similar age-related flattening of these SOD circadian rhythms has been observed, indicating a possible regulatory effect of
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supplementary materials given at the end of this article). Figure 4 Ghsr M/M rats show preserved circadian locomotor, feeding and energy balance rhythms across feeding conditions. (A) Body composition at the start of the calorimetric experiment in
Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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Department of Discovery Technologies and
Department of CNS Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
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phase induces a phase shift in the circadian rhythm ( Nakahara et al. 2004 ). We observed no difference in the intestinal transit of a charcoal-based marker between wild-type and NmU Tg mice. Although NmU stimulates ileal smooth muscle