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Hannah J Welters
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Alina Oknianska
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Kai S Erdmann Institute of Biomedical and Clinical Science, Department of Biochemistry II, Institut fuer Zellbiologie (Tumorforschung), Peninsula Medical School, Universities of Exeter and Plymouth, John Bull Building, Research Way, Plymouth PL6 8BU, UK

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Gerhart U Ryffel Institute of Biomedical and Clinical Science, Department of Biochemistry II, Institut fuer Zellbiologie (Tumorforschung), Peninsula Medical School, Universities of Exeter and Plymouth, John Bull Building, Research Way, Plymouth PL6 8BU, UK

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Noel G Morgan
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revealed that a range of components of the Wnt pathway are expressed at the mRNA level in INS-1 cells, including several frizzled receptors, a number of Wnt ligands and various members of the Wnt-regulated ‘destruction complex’, notably β-catenin, APC, axin

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-07-0262
Volume/Issue:
Volume 197: Issue 3
Free access
Spyridon Champeris Tsaniras Diabetes Research Group, Division of Reproduction and Endocrinology, King's College London, Hodgkin Building (2.10N), Guy's Campus, London SE1 1UL, UK

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Peter M Jones Diabetes Research Group, Division of Reproduction and Endocrinology, King's College London, Hodgkin Building (2.10N), Guy's Campus, London SE1 1UL, UK

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endoderm, inhibition of the Wnt pathway has not yet been employed in in vitro differentiation protocols designed to generate endocrine pancreas. There is a long list of compounds that can inhibit this pathway at different levels. Some are endogenous

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-10-0073
Volume/Issue:
Volume 206: Issue 1
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Débora Cristina de Moraes
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Mario Vaisman Laboratório de Endocrinologia Molecular, Hospital Universitário Clementino Fraga Filho, Instituto de Biofísica Carlos Chagas Filho, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho, s/n, Rio de Janeiro CEP 21949-900, Brasil

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Flavia Lucia Conceição Laboratório de Endocrinologia Molecular, Hospital Universitário Clementino Fraga Filho, Instituto de Biofísica Carlos Chagas Filho, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho, s/n, Rio de Janeiro CEP 21949-900, Brasil

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Tânia Maria Ortiga-Carvalho
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(FGF; Ericson et al . 1998 ) and wingless (WNT) pathways ( Rizzoti & Lovell-Badge 2005 ). Figure 1 Early pituitary development. The most anterior portion of the neural plate gives rise to the anterior pituitary and the adjacent midline region forms

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0229
Volume/Issue:
Volume 215: Issue 2
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Shiyun Tong Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Shumin Yang Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Ting Li Department of Endocrinology, The First Affiliated Hospital of Chengdu Medical College, Chengdu, China

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Rufei Gao School of Public Health and Management, Chongqing Medical University, Chongqing, China

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Jinbo Hu Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Ting Luo Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Hua Qing Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Qianna Zhen Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Renzhi Hu Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Xuan Li Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Yi Yang Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Chuan Peng The Chongqing Key Laboratory of Translational Medicine in Major Metabolic Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Qifu Li Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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-015-0801-5 ) 26321107 10.1007/s00592-015-0801-5 Hui L Li H Lu G Chen Z Sun W Shi Y Fu Z Huang B Zhu X Lu W , 2018 Low dose of bisphenol A modulates ovarian cancer gene expression profile and promotes epithelial to mesenchymal transition via canonical Wnt pathway

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DOI:
https://doi.org/10.1530/JOE-18-0608
Volume/Issue:
Volume 241: Issue 2
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Jui-Cheng Hsieh Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, Arizona 85004-2157, USA

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Rudolf C Estess Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, Arizona 85004-2157, USA

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Ichiro Kaneko Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, Arizona 85004-2157, USA
Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, Arizona 85004-2157, USA

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G Kerr Whitfield Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, Arizona 85004-2157, USA

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Peter W Jurutka Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, Arizona 85004-2157, USA
Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, Arizona 85004-2157, USA

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Mark R Haussler Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, Arizona 85004-2157, USA

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member of the Dickkopf family of secreted proteins, several of which regulate signaling by the canonical Wnt pathway ( Niehrs 2006 ). Thompson et al . (2006) have shown that DkkL1 expression is measurable in hair follicles of mice and peaks during

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0212
Volume/Issue:
Volume 220: Issue 2
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Tianru Jin Departments of Medicine, Division of Cell and Molecular Biology, Physiology, and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
Departments of Medicine, Division of Cell and Molecular Biology, Physiology, and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada

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be determined signaling pathway ( Yi et al . 2008 ). Finally, hormones and growth factors that use GPCR as their receptors may crosstalk with the Wnt pathway via two potential mechanisms. First, a GPCR may stabilize β-cat via PI3K activation

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0085
Volume/Issue:
Volume 198: Issue 1
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Ichiro Kaneko Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 N. Fifth Street, Phoenix, Arizona 85004, USA
Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 N. Fifth Street, Phoenix, Arizona 85004, USA

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Rimpi K Saini Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 N. Fifth Street, Phoenix, Arizona 85004, USA

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Kristin P Griffin Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 N. Fifth Street, Phoenix, Arizona 85004, USA

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G Kerr Whitfield Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 N. Fifth Street, Phoenix, Arizona 85004, USA

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Mark R Haussler Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 N. Fifth Street, Phoenix, Arizona 85004, USA

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Peter W Jurutka Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 N. Fifth Street, Phoenix, Arizona 85004, USA
Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 N. Fifth Street, Phoenix, Arizona 85004, USA

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) target; this action of PTH was abrogated by added sclerostin. Therefore, PTH increases FGF23 through the PKA and Wnt pathways ( Lavi-Moshayoff et al . 2010 ). Thus, by analogy with PTH action on FGF23 expression, we suspect that the response of FGF23

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-15-0225
Volume/Issue:
Volume 226: Issue 3
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Virginia Rider Department of Biology, Pittsburg State University, Pittsburg, Kansas, USA

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Alex Talbott Department of Biology, Pittsburg State University, Pittsburg, Kansas, USA

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Anuradha Bhusri Department of Biology, Pittsburg State University, Pittsburg, Kansas, USA

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Zach Krumsick Department of Biology, Pittsburg State University, Pittsburg, Kansas, USA

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Sierra Foster Department of Biology, Pittsburg State University, Pittsburg, Kansas, USA

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Joshua Wormington Department of Biology, Pittsburg State University, Pittsburg, Kansas, USA

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Bruce F Kimler Department of Radiation Oncology, The University of Kansas Medical Center, Kansas City, Kansas, USA

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preimplantation uterus . Molecular Endocrinology 17 610 – 627 . ( doi:10.1210/me.2002-0290 ) Zimmerman ZF Moon RT Chien AJ 2012 Targeting Wnt pathways in disease . Cold Spring Harbor Perspectives in Biology 4 1 – 24 . ( doi:10

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https://doi.org/10.1530/JOE-15-0523
Volume/Issue:
Volume 229: Issue 2
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Amrutha Bagivalu Lakshminarasimha Institute of Zoology, University of Cologne, Cologne, Germany

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Madhuri Puvvada Institute of Zoology, University of Cologne, Cologne, Germany

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Matthias Hammerschmidt Institute of Zoology, University of Cologne, Cologne, Germany

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Maximilian Michel Institute of Zoology, University of Cologne, Cologne, Germany

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-0437 ) 33705349 Kamstra K Rizwan MZ Grattan DR Horsfield JA Tups A 2022 Leptin regulates glucose homeostasis via the canonical Wnt pathway in the zebrafish . FASEB Journal 36 e22207. ( https://doi.org/10.1096/fj.202101764R ) 35188286 Kang J Hu

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-22-0026
Volume/Issue:
Volume 254: Issue 1
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Michela Rossi Bone Physiopathology Unit, Genetics and Rare Diseases Research Area, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

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Giulia Battafarano Bone Physiopathology Unit, Genetics and Rare Diseases Research Area, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

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Viviana De Martino Department of Clinical, Internal, Anaesthesiology and Cardiovascular Sciences, Sapienza University, Rome, Italy

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Alfredo Scillitani Endocrinology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Casa Sollievo della Sofferenza, Foggia, Italy

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Salvatore Minisola Department of Clinical, Internal, Anaesthesiology and Cardiovascular Sciences, Sapienza University, Rome, Italy

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Andrea Del Fattore Bone Physiopathology Unit, Genetics and Rare Diseases Research Area, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

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figure was produced using Servier Medical Art. A full colour version of this figure is available at https://doi.org/10.1530/JOE-20-0285 . In spite of that, LRP4 overexpression enhances the efficacy of sclerostin in the WNT pathway while its

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-20-0285
Volume/Issue:
Volume 248: Issue 2
Free access