Search Results
Search for other papers by Cristina Velasco in
Google Scholar
PubMed
Search for other papers by Marta Librán-Pérez in
Google Scholar
PubMed
Search for other papers by Cristina Otero-Rodiño in
Google Scholar
PubMed
Search for other papers by Marcos A López-Patiño in
Google Scholar
PubMed
Search for other papers by Jesús M Míguez in
Google Scholar
PubMed
Search for other papers by José Miguel Cerdá-Reverter in
Google Scholar
PubMed
Search for other papers by José L Soengas in
Google Scholar
PubMed
, ultimately leading to decreased food intake ( Migrenne et al . 2007 , Blouet & Schwartz 2010 ). Our previous studies in fish have characterized the presence and function of fatty acid-sensing systems in the hypothalamus of rainbow trout ( Oncorh ynchus
Laboratory of Metabolic Disorders (LABDIME), School of Applied Sciences (FCA), University of Campinas (UNICAMP), Limeira, São Paulo, Brazil
Search for other papers by Mariana Rosolen Tavares in
Google Scholar
PubMed
Search for other papers by Simone Ferreira Lemes in
Google Scholar
PubMed
Search for other papers by Thais de Fante in
Google Scholar
PubMed
Search for other papers by Cristina Saenz de Miera in
Google Scholar
PubMed
Laboratory of Metabolic Disorders (LABDIME), School of Applied Sciences (FCA), University of Campinas (UNICAMP), Limeira, São Paulo, Brazil
Search for other papers by Isadora Carolina Betim Pavan in
Google Scholar
PubMed
Search for other papers by Rosangela Maria Neves Bezerra in
Google Scholar
PubMed
Search for other papers by Patricia Oliveira Prada in
Google Scholar
PubMed
Search for other papers by Marcio Alberto Torsoni in
Google Scholar
PubMed
Search for other papers by Carol Fuzeti Elias in
Google Scholar
PubMed
Laboratory of Metabolic Disorders (LABDIME), School of Applied Sciences (FCA), University of Campinas (UNICAMP), Limeira, São Paulo, Brazil
Search for other papers by Fernando Moreira Simabuco in
Google Scholar
PubMed
, osteoarthritis, and some types of cancer ( James et al. 2006 , Tremblay & Lachance 2017 ). Thus, there is a great demand for research involving metabolic processes related to the obesity onset. Hypothalamus is an important region of the central nervous system
Search for other papers by Anaies Nazarians-Armavil in
Google Scholar
PubMed
Search for other papers by Jennifer A Chalmers in
Google Scholar
PubMed
Search for other papers by Claire B Lee in
Google Scholar
PubMed
Search for other papers by Wenqing Ye in
Google Scholar
PubMed
Departments of Physiology, Obstetrics and Gynaecology, Medicine, Division of Cellular and Molecular Biology
Departments of Physiology, Obstetrics and Gynaecology, Medicine, Division of Cellular and Molecular Biology
Departments of Physiology, Obstetrics and Gynaecology, Medicine, Division of Cellular and Molecular Biology
Search for other papers by Denise D Belsham in
Google Scholar
PubMed
Introduction The hypothalamus is largely responsible for the integration of peripheral cues, such as hormones and nutrients, to direct appropriate physiological processes to maintain energy balance. Disruption in this equilibrium results in the
Department of Pediatrics, Department of Medicine, Department of Pediatric Endocrinology, Endocrinology and Metabolism, Developmental Biology and Cancer Programme, Department of Pharmacology and Therapeutics, Center for Reproductive Medicine, Leiden University Medical Center, Leiden, The Netherlands
Search for other papers by Sjoerd D Joustra in
Google Scholar
PubMed
Search for other papers by Onno C Meijer in
Google Scholar
PubMed
Department of Pediatrics, Department of Medicine, Department of Pediatric Endocrinology, Endocrinology and Metabolism, Developmental Biology and Cancer Programme, Department of Pharmacology and Therapeutics, Center for Reproductive Medicine, Leiden University Medical Center, Leiden, The Netherlands
Search for other papers by Charlotte A Heinen in
Google Scholar
PubMed
Search for other papers by Isabel M Mol in
Google Scholar
PubMed
Search for other papers by El Houari Laghmani in
Google Scholar
PubMed
Search for other papers by Rozemarijn M A Sengers in
Google Scholar
PubMed
Search for other papers by Gabriela Carreno in
Google Scholar
PubMed
Search for other papers by A S Paul van Trotsenburg in
Google Scholar
PubMed
Search for other papers by Nienke R Biermasz in
Google Scholar
PubMed
Search for other papers by Daniel J Bernard in
Google Scholar
PubMed
Search for other papers by Jan M Wit in
Google Scholar
PubMed
Search for other papers by Wilma Oostdijk in
Google Scholar
PubMed
Search for other papers by Ans M M van Pelt in
Google Scholar
PubMed
Search for other papers by Geert Hamer in
Google Scholar
PubMed
Search for other papers by Gerry T M Wagenaar in
Google Scholar
PubMed
dehydration in a graded alcohol series and xylenes. Real-time qPCR Relative Igsf1 mRNA expression was assessed in various organs (four to six animals, both sexes), as well as punches from choroid plexus (lateral ventricle of the brain), hypothalamus
Department of Molecules and Circuits, CNRS UMR 9197, Molecular Neuroendocrinology of Food Intake, Paris-Saclay Institute of Neuroscience, Orsay, France
Department of Geriatrics, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China
Search for other papers by Jie Miao in
Google Scholar
PubMed
Department of Molecules and Circuits, CNRS UMR 9197, Molecular Neuroendocrinology of Food Intake, Paris-Saclay Institute of Neuroscience, Orsay, France
Search for other papers by Yacir Benomar in
Google Scholar
PubMed
Search for other papers by Sarah Al Rifai in
Google Scholar
PubMed
Department of Molecules and Circuits, CNRS UMR 9197, Molecular Neuroendocrinology of Food Intake, Paris-Saclay Institute of Neuroscience, Orsay, France
Search for other papers by Ghislaine Poizat in
Google Scholar
PubMed
Department of Molecules and Circuits, CNRS UMR 9197, Molecular Neuroendocrinology of Food Intake, Paris-Saclay Institute of Neuroscience, Orsay, France
Search for other papers by Laure Riffault in
Google Scholar
PubMed
Department of Molecules and Circuits, CNRS UMR 9197, Molecular Neuroendocrinology of Food Intake, Paris-Saclay Institute of Neuroscience, Orsay, France
Search for other papers by Delphine Crépin in
Google Scholar
PubMed
Department of Molecules and Circuits, CNRS UMR 9197, Molecular Neuroendocrinology of Food Intake, Paris-Saclay Institute of Neuroscience, Orsay, France
Search for other papers by Mohammed Taouis in
Google Scholar
PubMed
manually dissected and immediately frozen into liquid nitrogen and conserved at −80°C. The quality of the dissection was verified by the measurement of POMC and NPY expression known to be specific to the hypothalamus. All procedures were conducted according
Search for other papers by Gisela Helfer in
Google Scholar
PubMed
Search for other papers by Qing-Feng Wu in
Google Scholar
PubMed
of the hippocampus as well as ependymal cells and tanycytes lining the third ventricle of the hypothalamus ( Guo et al . 2012 , Helfer et al . 2016 ). CMKLR1 is a G i/o -protein-coupled receptor that signals through mitogen-activated protein kinase
Search for other papers by Leila Arbabi in
Google Scholar
PubMed
Search for other papers by Qun Li in
Google Scholar
PubMed
Search for other papers by Belinda A Henry in
Google Scholar
PubMed
Search for other papers by Iain J Clarke in
Google Scholar
PubMed
-4 reduced expression of the kisspeptin (Kiss1) ( KISS1 ) and Kiss1 receptor ( GPR54 ) genes in the hypothalamus, with little effect of GLP-1; GLP-1 had a transient stimulatory effect on KISS1 expression only ( Outeiriño-Iglesias et al. 2015
Centre for Paediatrics and Child Health, Department of Paediatric Endocrinology, Department of Endocrinology, Centre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, M13 9WL, UK
Search for other papers by P G Murray in
Google Scholar
PubMed
Centre for Paediatrics and Child Health, Department of Paediatric Endocrinology, Department of Endocrinology, Centre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, M13 9WL, UK
Search for other papers by C E Higham in
Google Scholar
PubMed
Centre for Paediatrics and Child Health, Department of Paediatric Endocrinology, Department of Endocrinology, Centre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, M13 9WL, UK
Search for other papers by P E Clayton in
Google Scholar
PubMed
‘releasing’ factors originated from neurones in the hypothalamus and entered into the portal blood. With regard to the growth hormone (GH) axis, work in the 1960s showed that intra-carotid injection of stalk-median eminence extracts into rats and guinea pigs
Search for other papers by Margaret B Allison in
Google Scholar
PubMed
Search for other papers by Martin G Myers Jr in
Google Scholar
PubMed
the brain, especially the hypothalamus, where its action is integrated with that of other adipokines, gastrokines, and other signals to coordinate energy homeostasis ( Friedman & Halaas 1998 , Bates & Myers 2003 , Myers et al . 2009 , Ring
Search for other papers by J T Smith in
Google Scholar
PubMed
Unit of Experimental Therapeutics, Institute of Cancer Sciences, University of Glasgow Glasgow, UK
Search for other papers by A Roseweir in
Google Scholar
PubMed
Search for other papers by M Millar in
Google Scholar
PubMed
Search for other papers by I J Clarke in
Google Scholar
PubMed
Institute for Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
Search for other papers by R P Millar in
Google Scholar
PubMed
1995 The role of neuropeptide Y (NPY) in the control of LH secretion in the ewe with respect to season, NPY receptor subtype and the site of action in the hypothalamus . European Journal of Endocrinology 147 565 – 579 . ( https://doi.org/10