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Introduction The various functions of prolactin (PRL) in vertebrates include the growth and differentiation of mammary epithelium, lactation in mammals, osmoregulation and parental behavior in teleosts, amphibian development
Lactation and Mammary Gland Biology Group, Department of Animal Science, US Meat Animal Research Center, Agriculture and Agri-Food Canada, Department of Physiology, Department of Animal Science, Department of Animal Science, The University of Vermont, 570 Main Street, Burlington, Vermont 05405, USA
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Lactation and Mammary Gland Biology Group, Department of Animal Science, US Meat Animal Research Center, Agriculture and Agri-Food Canada, Department of Physiology, Department of Animal Science, Department of Animal Science, The University of Vermont, 570 Main Street, Burlington, Vermont 05405, USA
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Lactation and Mammary Gland Biology Group, Department of Animal Science, US Meat Animal Research Center, Agriculture and Agri-Food Canada, Department of Physiology, Department of Animal Science, Department of Animal Science, The University of Vermont, 570 Main Street, Burlington, Vermont 05405, USA
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Introduction The polypeptide hormone prolactin (PRL) regulates numerous physiological functions across multiple species. In pigs, PRL exerts its most significant effects on mammary gland growth ( Farmer et al . 2000 ), lactation ( Farmer et al
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Introduction During late gestation, ovine fetal prolactin (PRL) secretion is maintained by a tonic stimulatory, rather than inhibitory, drive from the hypothalamus ( Houghton et al. 1995 , McMillen et al. 2001 ). Plasma PRL
Departments of Animal Science,
Biochemistry, Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel
Department of Obstetrics and Gynecology, Kaplan Medical Center, Rehovot, Affiliated to the Hebrew University School of Medicine, Jerusalem, Israel
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Departments of Animal Science,
Biochemistry, Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel
Department of Obstetrics and Gynecology, Kaplan Medical Center, Rehovot, Affiliated to the Hebrew University School of Medicine, Jerusalem, Israel
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Departments of Animal Science,
Biochemistry, Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel
Department of Obstetrics and Gynecology, Kaplan Medical Center, Rehovot, Affiliated to the Hebrew University School of Medicine, Jerusalem, Israel
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Departments of Animal Science,
Biochemistry, Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel
Department of Obstetrics and Gynecology, Kaplan Medical Center, Rehovot, Affiliated to the Hebrew University School of Medicine, Jerusalem, Israel
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Departments of Animal Science,
Biochemistry, Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel
Department of Obstetrics and Gynecology, Kaplan Medical Center, Rehovot, Affiliated to the Hebrew University School of Medicine, Jerusalem, Israel
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-α , and prolactin regulate leptin expression at the adipose tissue ( Fruhbeck 2001 ). Prolactin, a hormone secreted from the pituitary acidophil cells, plays an important role in the morphological and biochemical differentiation of the epithelial cells
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SUMMARY
Isoelectric focusing in polyacrylamide gel followed by staining with Coomassie brilliant blue was used for the densitometric estimation of ovine prolactin standard and canine pituitary prolactin. The results were compared with those obtained by conventional polyacrylamide gel electrophoretic procedures and isoelectric focusing was found to be a valid technique for the estimation of prolactin and to offer greater technical convenience.
The mobility of ovine and canine prolactin was similar in isoelectric focusing and gel electrophoresis. The isoelectric point of ovine and canine prolactin was found to be 6·17 and 6·61 respectively.
Constant levels of prolactin were found in the pituitaries of bitches at oestrus.
Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
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Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
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University of Chemistry and Technology, Prague, Czech Republic
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antiobesity drugs. Prolactin-releasing peptide in food intake regulation The anorexigenic neuropeptide prolactin-releasing peptide (PrRP) was initially isolated from the hypothalamus as a ligand for the human orphan G-protein-coupled receptor GPR10
Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Campus UNAM-Juriquilla, 76230 Querétaro, México
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Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Campus UNAM-Juriquilla, 76230 Querétaro, México
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Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Campus UNAM-Juriquilla, 76230 Querétaro, México
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Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Campus UNAM-Juriquilla, 76230 Querétaro, México
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Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Campus UNAM-Juriquilla, 76230 Querétaro, México
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Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Campus UNAM-Juriquilla, 76230 Querétaro, México
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Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Campus UNAM-Juriquilla, 76230 Querétaro, México
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Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Campus UNAM-Juriquilla, 76230 Querétaro, México
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Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Campus UNAM-Juriquilla, 76230 Querétaro, México
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are unclear and little is known about the regulatory factors responsible for their control. Prolactin (PRL) acts both as a circulating hormone and as a cytokine in a vast array of physiological functions that range from reproduction and
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Introduction Prolactin (PRL) is a polypeptide hormone synthesized and secreted from specialized cells of the anterior pituitary gland, which is known for its multiple effects on the female mammary gland, including regulation of growth and
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Department of Pediatrics, University of Kansas Medical Center, Kansas City, Kansas, USA
Department of Obstetrics and Gynecology, University of Kansas Medical Center, Kansas City, Kansas, USA
Center for Perinatal Research, Children’s Research Institute, Children’s Mercy, Kansas City, Missouri, USA
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. 2009 , Rieck & Kaestner 2010 , Huang 2013 ). It is hypothesized that these maternal pancreatic adaptations are driven by the pregnancy hormones, prolactin (PRL) and placental lactogens (PLs), acting through the PRL receptor (PRLR) at the β cells
Laboratory of Hormones and Receptors, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilova Str., 119991, Moscow, Russian Federation
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Laboratory of Hormones and Receptors, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilova Str., 119991, Moscow, Russian Federation
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Laboratory of Hormones and Receptors, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilova Str., 119991, Moscow, Russian Federation
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Laboratory of Hormones and Receptors, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilova Str., 119991, Moscow, Russian Federation
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Laboratory of Hormones and Receptors, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilova Str., 119991, Moscow, Russian Federation
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Introduction Several prolactin receptor (PrlR) isoforms have been identified in mammals. In rat, they have been shown to be produced via alternative splicing of PrlR pre-mRNA: the formation of long and short isoforms result from