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GTA CTG TGA ATA TAG CAC CAA A-3′, reverse 5′-AGC AAT ATC ATA TTT ATA TTC ACT TGA CAA ATT CAT-3′; glutathione_peroxi-dase_2 (NM_030677): forward 5′-TGC CAT CTA GAT GAG AGC TGC T-3′, reverse 5′-CAG ACT GGC TCT GGA CCC TT-3′; retinol_binding_protein_7
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arthritis ( Schultz et al . 2010 , Ogata et al . 2011 , Ye & McGuinness 2013 ). Rbp4 Rbp4 is a transport protein for retinol in systemic circulation, and is mainly produced by the liver but also expressed in white adipocytes. Rbp4 was first characterized
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Department of Physiology, Turku Center for Disease Modeling, Institute of Biomedicine, University of Turku, Kiinamyllynkatu 10, FI-20014 Turku, Finland
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Department of Physiology, Turku Center for Disease Modeling, Institute of Biomedicine, University of Turku, Kiinamyllynkatu 10, FI-20014 Turku, Finland
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Department of Physiology, Turku Center for Disease Modeling, Institute of Biomedicine, University of Turku, Kiinamyllynkatu 10, FI-20014 Turku, Finland
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analyses have indicated that HSD17B2 is a close homologue of retinoid-converting enzymes and presents with a high sequence similarity to retinol dehydrogenase type 1 ( Chai et al . 1995 a , b , Simon et al . 1995 ). In addition, studies have shown that
Department of Biomedical Science and Technology, Institute of Biomedical Science and Technology, Konkuk University, 1 Hwayang-dong, Kwangjin-gu, Seoul 143-701, Korea
Laboratory of Reproductive Biology and Infertility, Cheil General Hospital, Women’s Healthcare Center, Seoul 100-380, Korea
Department of Biochemistry and Molecular Biology, UMDNJ-New Jersey Medical School, Newark, New Jersey 07101-1709, USA
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Department of Biomedical Science and Technology, Institute of Biomedical Science and Technology, Konkuk University, 1 Hwayang-dong, Kwangjin-gu, Seoul 143-701, Korea
Laboratory of Reproductive Biology and Infertility, Cheil General Hospital, Women’s Healthcare Center, Seoul 100-380, Korea
Department of Biochemistry and Molecular Biology, UMDNJ-New Jersey Medical School, Newark, New Jersey 07101-1709, USA
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Department of Biomedical Science and Technology, Institute of Biomedical Science and Technology, Konkuk University, 1 Hwayang-dong, Kwangjin-gu, Seoul 143-701, Korea
Laboratory of Reproductive Biology and Infertility, Cheil General Hospital, Women’s Healthcare Center, Seoul 100-380, Korea
Department of Biochemistry and Molecular Biology, UMDNJ-New Jersey Medical School, Newark, New Jersey 07101-1709, USA
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Department of Biomedical Science and Technology, Institute of Biomedical Science and Technology, Konkuk University, 1 Hwayang-dong, Kwangjin-gu, Seoul 143-701, Korea
Laboratory of Reproductive Biology and Infertility, Cheil General Hospital, Women’s Healthcare Center, Seoul 100-380, Korea
Department of Biochemistry and Molecular Biology, UMDNJ-New Jersey Medical School, Newark, New Jersey 07101-1709, USA
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Department of Biomedical Science and Technology, Institute of Biomedical Science and Technology, Konkuk University, 1 Hwayang-dong, Kwangjin-gu, Seoul 143-701, Korea
Laboratory of Reproductive Biology and Infertility, Cheil General Hospital, Women’s Healthcare Center, Seoul 100-380, Korea
Department of Biochemistry and Molecular Biology, UMDNJ-New Jersey Medical School, Newark, New Jersey 07101-1709, USA
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Department of Biomedical Science and Technology, Institute of Biomedical Science and Technology, Konkuk University, 1 Hwayang-dong, Kwangjin-gu, Seoul 143-701, Korea
Laboratory of Reproductive Biology and Infertility, Cheil General Hospital, Women’s Healthcare Center, Seoul 100-380, Korea
Department of Biochemistry and Molecular Biology, UMDNJ-New Jersey Medical School, Newark, New Jersey 07101-1709, USA
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Department of Biomedical Science and Technology, Institute of Biomedical Science and Technology, Konkuk University, 1 Hwayang-dong, Kwangjin-gu, Seoul 143-701, Korea
Laboratory of Reproductive Biology and Infertility, Cheil General Hospital, Women’s Healthcare Center, Seoul 100-380, Korea
Department of Biochemistry and Molecular Biology, UMDNJ-New Jersey Medical School, Newark, New Jersey 07101-1709, USA
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, Ludwig et al. 2000 , IJpenberg et al. 2004 ). For example, DR1 and DR2 found in the promoter of cellular retinol-binding protein II (CRABPII) are shown to be activated by both RXR/RXR homodimer and RAR/RXR heterodimer ( Durand et al. 1992
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Department of Human Metabolism, Robert Hague Centre for Diabetes and Endocrinology, Medical School, The University of Sheffield, Sheffield S10 2RX, UK
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, lipoprotein lipase; LXR, liver X receptor; MTTP, microsomal triglyceride transfer protein; PPARγ, peroxisome proliferator-activated receptor γ; RBP4, retinol-binding protein-4; Scd1, stearoyl-CoA desaturase 1; SR-1B, scavenger receptor class B member 1; SREBP
Department of Metabolic Medicine, Graduate School of Frontier Bioscience, Japan Society for the Promotion of Science Research, Institute of Clinical Research, Department of Internal Medicine, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita-shi, Osaka 565-0871, Japan
Department of Metabolic Medicine, Graduate School of Frontier Bioscience, Japan Society for the Promotion of Science Research, Institute of Clinical Research, Department of Internal Medicine, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita-shi, Osaka 565-0871, Japan
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Department of Metabolic Medicine, Graduate School of Frontier Bioscience, Japan Society for the Promotion of Science Research, Institute of Clinical Research, Department of Internal Medicine, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita-shi, Osaka 565-0871, Japan
Department of Metabolic Medicine, Graduate School of Frontier Bioscience, Japan Society for the Promotion of Science Research, Institute of Clinical Research, Department of Internal Medicine, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita-shi, Osaka 565-0871, Japan
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activator inhibitor type-I, resistin, and retinol-binding protein 4 ( Hotamisligil & Spiegelman 1994 , Zhang et al . 1994 , Maeda et al . 1996 , Shimomura et al . 1996 , Steppan et al . 2001 , Yang et al . 2005 ). Dysregulated production of
University Paris sud, bat 447, 91405 Orsay Cedex, France
Faculty of Agriculture, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot 76100, Israel
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University Paris sud, bat 447, 91405 Orsay Cedex, France
Faculty of Agriculture, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot 76100, Israel
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University Paris sud, bat 447, 91405 Orsay Cedex, France
Faculty of Agriculture, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot 76100, Israel
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University Paris sud, bat 447, 91405 Orsay Cedex, France
Faculty of Agriculture, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot 76100, Israel
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University Paris sud, bat 447, 91405 Orsay Cedex, France
Faculty of Agriculture, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot 76100, Israel
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per kilogram diet: retinol acetate, 3800 μg; cholecalciferol, 60 μg; α-tocopherol, 30 mg; menadione, 1.5 mg; thiamin, 1.5 mg; riboflavin, 4 mg; pyridoxine, 2 mg; cobalamin, 20 μg; niacin, 30 mg; biotin, 70 μg; folic acid, 1 mg; pantothenic acid, 10 mg
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clusters that separated the genes with similar actions were detected: retinol, arachidonic acid and linoleic acid metabolism; FA oxidation; metabolic pathways with anti-inflammatory actions ( Table 5 ). Table 3 Hepatic up- and downregulated genes in
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MH Sullivan LM Ingram C O’Donnell CJ Keaney JF Vasan RS 2012 Cardiometabolic correlates and heritability of fetuin-A, retinol-binding protein 4, and fatty-acid binding protein 4 in the Framingham Heart Study . Journal of
School of Medicine, Conjoint Endocrine Laboratory, Disciplines of Medicine, Royal Brisbane and Women's Hospital, The University of Queensland, Herston, Brisbane, Queensland 4029, Australia
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School of Medicine, Conjoint Endocrine Laboratory, Disciplines of Medicine, Royal Brisbane and Women's Hospital, The University of Queensland, Herston, Brisbane, Queensland 4029, Australia
School of Medicine, Conjoint Endocrine Laboratory, Disciplines of Medicine, Royal Brisbane and Women's Hospital, The University of Queensland, Herston, Brisbane, Queensland 4029, Australia
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School of Medicine, Conjoint Endocrine Laboratory, Disciplines of Medicine, Royal Brisbane and Women's Hospital, The University of Queensland, Herston, Brisbane, Queensland 4029, Australia
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recently reported that human trophoblast cells produce the T 4 and retinol-binding protein, TTR ( McKinnon et al . 2005 ). Studies on polarised choriocarcinoma JEG-3 cells maintained in bicameral chambers indicate that TTR is secreted apically and basally