Search Results

You are looking at 21 - 30 of 78 items for :

  • embryo protection x
  • Refine by Access: All content x
Clear All
Free access

O A Sukocheva and D O Carpenter

-induced apoptosis (Fig. 1C ) that activated the mitochondrial death pathway independently from death receptors. Our results indicate that in hepatocytes, T 3 selectively inhibits DRL-mediated apoptosis, and the observed protection does not result from a general

Free access

Lucas Monje, Jorgelina Varayoud, Enrique H Luque, and Jorge G Ramos

observed adverse effects level (LOAEL) established by the National Toxicology Program’s report (US Environmental Protection Agency 1993) is 50 mg/kg per day, there are several reports indicating that perinatal exposure to BPA in doses below LOAEL affects

Free access

A G Kayali, A Stotland, K V Gunst, M Kritzik, G Liu, S Dabernat, Y-Q Zhang, W Wu, and N Sarvetnick

involved primarily in proliferation, migration and differentiation in the embryo ( Ornitz & Itoh 2001 ). In the adult, FGFs are associated with tissue repair and response to injury ( Floss et al. 1997 ). The expression of dominant negative forms of either

Free access

Madeleine R Di Natale, Alita Soch, Ilvana Ziko, Simone N De Luca, Sarah J Spencer, and Luba Sominsky

different conditions have been demonstrated in at least one study, whereby both exogenous ghrelin and inhibition of endogenous ghrelin by d -Lys3 exerted negative effects on fertilisation and early embryo development ( Luque et al. 2014 ). These data

Free access

R G Ahmed

substitutions ( Leijs et al . 2012 ). In the United States, PCBs are manufactured as complex mixtures under the trade name Aroclor with a designation indicating the extent of chlorination ( Karcher et al . 2004 ). The U.S. Environmental Protection Agency also

Free access

Guangcui Xu, Tingting Yan, Qiang Peng, Haibin Li, Weidong Wu, Xianwen Yi, and Yingzheng Zhao

. The elimination of Lias gene will lead to the embryo stop development, indicating that endogenous LA plays an irreplaceable role in antioxidant activity and energy regulation ( Yi & Maeda 2005 ). Previous studies have repeatedly proved that both

Free access

Timothy J Cole and Morag J Young

case in these cells allowing cortisol to regulate transcriptional responses via a nuclear receptor in addition to GR. Moreover, cortisol can have both agonist and antagonist actions at the MR depending on cell context and whether enzymatic ‘protection

Free access

Nicole M Templeman, Søs Skovsø, Melissa M Page, Gareth E Lim, and James D Johnson

restricted to the pancreas ( Mehran et al . 2012 , Thorens et al . 2015 ), and it does not contribute as much to pancreatic insulin production as Ins2 , except in the mouse embryo during the early stages of pancreatic development ( Wentworth et al . 1986

Free access

C Zermeño, J Guzmán-Morales, Y Macotela, G Nava, F López-Barrera, J B Kouri, C Lavalle, G Martínez de la Escalera, and C Clapp

hypodiploid cells induced by low-serum. The two PRL concentrations were equally effective, and their protective action was abolished by heat denaturation (Fig. 3B ). PRL protection against apoptosis was confirmed by the detection of DNA strand breaks

Open access

Dawn E W Livingstone, Emma M Di Rollo, Tracy C-S Mak, Karen Sooy, Brian R Walker, and Ruth Andrew

Embryos (C57Bl6/SvEv/129) with targeted disruption of 5αR1 (Jackson Laboratory) ( Mahendroo et al. 1996 ) were re-derived ( Livingstone et al. 2014 ) and allowed free access to double-filtered drinking water and standard chow (7.4% fat, 4% sucrose; RM1