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Caitlin S Wyrwoll School of Anatomy and Human Biology, School of Medicine and Pharmacology, The University of Western Australia, 35 Stirling Hwy, Crawley, Perth, Western Australia 6009, Australia

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Peter J Mark School of Anatomy and Human Biology, School of Medicine and Pharmacology, The University of Western Australia, 35 Stirling Hwy, Crawley, Perth, Western Australia 6009, Australia

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Trevor A Mori School of Anatomy and Human Biology, School of Medicine and Pharmacology, The University of Western Australia, 35 Stirling Hwy, Crawley, Perth, Western Australia 6009, Australia

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Brendan J Waddell School of Anatomy and Human Biology, School of Medicine and Pharmacology, The University of Western Australia, 35 Stirling Hwy, Crawley, Perth, Western Australia 6009, Australia

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& Kelly 2006 ), whereas UCP3 promotes fatty acid oxidation ( MacLellan et al . 2005 ) and glucose uptake ( Huppertz et al . 2001 ), and limits mitochondrial damage via effects on lipid peroxidation ( Brand et al . 2002 ). The interactive effects of a

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0210
Volume/Issue:
Volume 198: Issue 3
Free access
Sihan Lv Department of Endocrinology, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, China

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Xinchen Qiu Department of Endocrinology, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, China
Translational Medical Center for Stem Cell Therapy & Institute for Regenerative Medicine, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China

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Jian Li Department of Endocrinology, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, China
Translational Medical Center for Stem Cell Therapy & Institute for Regenerative Medicine, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China

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Jinye Liang Translational Medical Center for Stem Cell Therapy & Institute for Regenerative Medicine, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China

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Weida Li Translational Medical Center for Stem Cell Therapy & Institute for Regenerative Medicine, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China

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Chao Zhang Translational Medical Center for Stem Cell Therapy & Institute for Regenerative Medicine, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China

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Zhen-Ning Zhang Translational Medical Center for Stem Cell Therapy & Institute for Regenerative Medicine, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China

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Bing Luan Department of Endocrinology, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, China

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& Karin 2012 ). Disrupted lipid metabolism including fatty acid oxidation and de novo lipogenesis in liver results in the development of hepatic steatosis and contributes to the development of hepatic insulin resistance ( Marchesini et al . 2003

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-16-0649
Volume/Issue:
Volume 234: Issue 2
Free access
Lihong Fu Shanghai National Research Center for Endocrine and Metabolic Diseases, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Yixuan Qiu Shanghai National Research Center for Endocrine and Metabolic Diseases, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Linyan Shen Shanghai National Research Center for Endocrine and Metabolic Diseases, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Department of Endocrinology, East Hospital, Tongji University School of Medicine, Shanghai, China

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Canqi Cui Shanghai National Research Center for Endocrine and Metabolic Diseases, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Shuang Wang BGI Genomics, BGI-Shenzhen, Shenzhen, China

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Shujie Wang Shanghai National Research Center for Endocrine and Metabolic Diseases, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Yun Xie Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Xinjie Zhao Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China

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Xianfu Gao Key Laboratory of Systems Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China

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Guang Ning Shanghai National Research Center for Endocrine and Metabolic Diseases, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Aifang Nie Shanghai National Research Center for Endocrine and Metabolic Diseases, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Yanyun Gu Shanghai National Research Center for Endocrine and Metabolic Diseases, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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fatty acid and cholesterol synthesis and on acetate metabolism in isolated rat hepatocytes . British Journal of Nutrition 74 209 – 219 . ( https://doi.org/10.1079/BJN19950124 ) 10.1079/BJN19950124 Devkota S Wang Y Musch MW Leone V Fehlner

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-17-0709
Volume/Issue:
Volume 238: Issue 2
Free access
Prasanthi P Koganti Department of Animal Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York, USA

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Vimal Selvaraj Department of Animal Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York, USA

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genes that could influence triglyceride metabolism in mice ( Leduc et al. 2011 ). Experimentally, we provided the first evidence linking TSPO/PBR and fatty acid oxidation (FAO) by demonstrating that TSPO/PBR deletion induces a shift in substrate

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-20-0189
Volume/Issue:
Volume 247: Issue 1
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Luana Lopes Souza
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Aline Cordeiro
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Lorraine Soares Oliveira
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Gabriela Silva Monteiro de Paula
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Larissa Costa Faustino
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Tania Maria Ortiga-Carvalho
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Karen Jesus Oliveira Biophysics Institute Carlos Chagas Filho, Department of Physiology and Pharmacology, Federal University of Rio de Janeiro, Centro de Ciências da Saúde, Avenida Carlos Chagas Filho, 373, Bloco G, Cidade Universitária - Ilha do Fundão, Rio de Janeiro - RJ 21941-902, Brazil

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Carmen Cabanelas Pazos-Moura
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suggest that n-3 PUFA effects on lipid metabolism are dependent on TH signaling in specific steps and, together with the marked upregulation of PPARα in liver of hypothyroid rats, suggests an important cross-talk between fatty acids and TH pathways in

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-11-0142
Volume/Issue:
Volume 211: Issue 1
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Filipe de Vadder Institut National de la Santé et de la Recherche Médicale, U1213, Lyon, France
Université Lyon 1, Villeurbanne, France
Université de Lyon, Lyon, France

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Gilles Mithieux Institut National de la Santé et de la Recherche Médicale, U1213, Lyon, France
Université Lyon 1, Villeurbanne, France
Université de Lyon, Lyon, France

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metabolized by the host intestinal enzymes, but are metabolized by the microbiota in the cecum and colon ( Macfarlane & Macfarlane 2003 ). The major products from the microbial fermentation are short-chain fatty acids (SCFAs), namely acetate, propionate and

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-17-0542
Volume/Issue:
Volume 236: Issue 2
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Fátima Pérez de Heredia Department of Physiology, University of Murcia, Murcia, 30100 Spain

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Elvira Larqué Department of Physiology, University of Murcia, Murcia, 30100 Spain

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Salvador Zamora Department of Physiology, University of Murcia, Murcia, 30100 Spain

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Marta Garaulet Department of Physiology, University of Murcia, Murcia, 30100 Spain

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, Sánchez et al . 2008 ). In addition, DHEA-S can modulate fatty acid (FA) metabolism, through up-regulation of hepatic enzymes involved in β-oxidation ( Waxman 1996 , Depreter et al . 2002 ). The relevance of FAs is far beyond their role as energy

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0432
Volume/Issue:
Volume 201: Issue 1
Free access
Chaoyi Zhang Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China

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Qianli Zhang Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China

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Zhihong Huang Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China

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Quan Jiang Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China

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: (A) Srebp-1c and (B) Accα , fatty acid transporter genes: (C) Cd36 and (D) Fabp4 , and fatty acid oxidation genes: (E) Pparα and (F) Cpt1α . Lipid metabolism-related genes were measured by qPCR and normalized to β-actin levels. Three

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-20-0077
Volume/Issue:
Volume 246: Issue 2
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Ricardo Rodríguez-Calvo Vascular Medicine and Metabolism Unit, Research Unit on Lipids and Atherosclerosis, ‘Sant Joan’ University Hospital, Universitat Rovira i Virgili, Institut de Investigació Sanitaria Pere Virgili (IISPV), Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Reus, Spain

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Josefa Girona Vascular Medicine and Metabolism Unit, Research Unit on Lipids and Atherosclerosis, ‘Sant Joan’ University Hospital, Universitat Rovira i Virgili, Institut de Investigació Sanitaria Pere Virgili (IISPV), Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Reus, Spain

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Josep M Alegret Department of Cardiology, Cardiovascular Research Group, ‘Sant Joan’ University Hospital, Universitat Rovira i Virgili, Institut de Investigació Sanitaria Pere Virgili (IISPV), Reus, Spain

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Alba Bosquet Vascular Medicine and Metabolism Unit, Research Unit on Lipids and Atherosclerosis, ‘Sant Joan’ University Hospital, Universitat Rovira i Virgili, Institut de Investigació Sanitaria Pere Virgili (IISPV), Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Reus, Spain

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Daiana Ibarretxe Vascular Medicine and Metabolism Unit, Research Unit on Lipids and Atherosclerosis, ‘Sant Joan’ University Hospital, Universitat Rovira i Virgili, Institut de Investigació Sanitaria Pere Virgili (IISPV), Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Reus, Spain

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Lluís Masana Vascular Medicine and Metabolism Unit, Research Unit on Lipids and Atherosclerosis, ‘Sant Joan’ University Hospital, Universitat Rovira i Virgili, Institut de Investigació Sanitaria Pere Virgili (IISPV), Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Reus, Spain

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Combined adipocyte-macrophage fatty acid-binding protein deficiency improves metabolism, atherosclerosis, and survival in apolipoprotein E-deficient mice . Circulation 110 1492 – 1498 . ( doi:10.1161/01.CIR.0000141735.13202.B6 ) Britton KA Fox

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DOI:
https://doi.org/10.1530/JOE-17-0031
Volume/Issue:
Volume 233: Issue 3
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Sabina Börner
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Michael Derno
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Sandra Hacke
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Ulrike Kautzsch
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Christine Schäff
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Sint ThanThan Research Unit Nutritional Physiology ‘Oskar Kellner’, Agriculture and Veterinary Medicine Inada-cho, Unit Genetics and Biometry, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany

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Hideto Kuwayama Research Unit Nutritional Physiology ‘Oskar Kellner’, Agriculture and Veterinary Medicine Inada-cho, Unit Genetics and Biometry, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany

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Harald M Hammon
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Monika Röntgen
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Rosemarie Weikard Research Unit Nutritional Physiology ‘Oskar Kellner’, Agriculture and Veterinary Medicine Inada-cho, Unit Genetics and Biometry, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany

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Christa Kühn Research Unit Nutritional Physiology ‘Oskar Kellner’, Agriculture and Veterinary Medicine Inada-cho, Unit Genetics and Biometry, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany

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Armin Tuchscherer Research Unit Nutritional Physiology ‘Oskar Kellner’, Agriculture and Veterinary Medicine Inada-cho, Unit Genetics and Biometry, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany

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Björn Kuhla
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characterized by high body fat mobilization. This suggests that, in addition to its role in preventing starvation, ghrelin exerts a prominent role in the regulation of fat metabolism. For example, feeding rumen-protected long-chain fatty acids increases the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0384
Volume/Issue:
Volume 216: Issue 2
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