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Kazuyuki Hoshijima Department of Biological Sciences, Tokyo Institute of Technology, 4259-B-19 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan

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Shigehisa Hirose Department of Biological Sciences, Tokyo Institute of Technology, 4259-B-19 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan

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. 2005 , Tsukada & Takei 2006 ). In zebrafish, the anp gene has been isolated and the expression is confined to the atrium during embryogenesis; the regulatory function remains unclear ( Berdougo et al. 2003 ). The renin–angiotensin system

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-07-0003
Volume/Issue:
Volume 193: Issue 3
Free access
Patricia D Maningat Department of Pediatrics - Nutrition, Baylor College of Medicine, Children's Nutrition Research Center # 7062, 1100 Bates, Houston, Texas 77030, USA

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Partha Sen Department of Pediatrics - Nutrition, Baylor College of Medicine, Children's Nutrition Research Center # 7062, 1100 Bates, Houston, Texas 77030, USA

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Agneta L Sunehag Department of Pediatrics - Nutrition, Baylor College of Medicine, Children's Nutrition Research Center # 7062, 1100 Bates, Houston, Texas 77030, USA

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Darryl L Hadsell Department of Pediatrics - Nutrition, Baylor College of Medicine, Children's Nutrition Research Center # 7062, 1100 Bates, Houston, Texas 77030, USA

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Morey W Haymond Department of Pediatrics - Nutrition, Baylor College of Medicine, Children's Nutrition Research Center # 7062, 1100 Bates, Houston, Texas 77030, USA

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mammary tissue. Therefore, a non-invasive technique permitting the analysis of gene expression in mammary epithelial cells would provide insight into the complex processes of milk production in humans. Milk fat is secreted by an apocrine mechanism unique

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-07-0394
Volume/Issue:
Volume 195: Issue 3
Free access
Teresa Priego Departamento de Fisiología, Facultad de Medicina, Universidad Complutense, Madrid 28040, Spain

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Miriam Granado Departamento de Fisiología, Facultad de Medicina, Universidad Complutense, Madrid 28040, Spain

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Estibaliz Castillero Departamento de Fisiología, Facultad de Medicina, Universidad Complutense, Madrid 28040, Spain

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Ana Isabel Martín Departamento de Fisiología, Facultad de Medicina, Universidad Complutense, Madrid 28040, Spain

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M Ángeles Villanúa Departamento de Fisiología, Facultad de Medicina, Universidad Complutense, Madrid 28040, Spain

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Asunción López-Calderón Departamento de Fisiología, Facultad de Medicina, Universidad Complutense, Madrid 28040, Spain

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administration is able to decrease liver IGF-I gene expression, acting independently of pituitary GH and liver GH receptors (GHR; Priego et al. 2003 ). In the liver, the endotoxin response in vivo is mediated by complex cellular interplay between the

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06938
Volume/Issue:
Volume 190: Issue 3
Free access
E H Leder National Center for Cool and Cold Water Aquaculture, Agricultural Research Service, United States Department of Agriculture, Kearneysville, West Virginia 25430, USA

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J T Silverstein National Center for Cool and Cold Water Aquaculture, Agricultural Research Service, United States Department of Agriculture, Kearneysville, West Virginia 25430, USA

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POMC-A and POMC-B. The present study focuses on the sequence divergence and expression patterns of the POMC genes of rainbow trout, including both POMC-A and POMC-B transcripts. Materials and Methods Fish care

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06283
Volume/Issue:
Volume 188: Issue 2
Free access
Mary Corless School of Biomolecular and Biomedical Sciences, Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland
School of Biomedical Sciences, University of Ulster, Coleraine, Northern Ireland, UK

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Aoife Kiely School of Biomolecular and Biomedical Sciences, Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland
School of Biomedical Sciences, University of Ulster, Coleraine, Northern Ireland, UK

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Neville H McClenaghan School of Biomolecular and Biomedical Sciences, Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland
School of Biomedical Sciences, University of Ulster, Coleraine, Northern Ireland, UK

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Peter R Flatt School of Biomolecular and Biomedical Sciences, Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland
School of Biomedical Sciences, University of Ulster, Coleraine, Northern Ireland, UK

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Philip Newsholme School of Biomolecular and Biomedical Sciences, Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland
School of Biomedical Sciences, University of Ulster, Coleraine, Northern Ireland, UK

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Newsholme et al. 2003 ). It has additionally been shown directly or indirectly to influence gene expression in specific target cells ( Curi et al. 2005 ). It is readily metabolized in islets and β-cell lines, such as BRIN-BD11 ( Malaisse et al. 1982 a

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06892
Volume/Issue:
Volume 190: Issue 3
Free access
Candida N Perera Purdue Cancer Center, Department of Biological Sciences

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Hwei G Chin Purdue Cancer Center, Department of Biological Sciences

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Nadire Duru Purdue Cancer Center, Department of Biological Sciences

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Ignacio G Camarillo Purdue Cancer Center, Department of Biological Sciences
Purdue Cancer Center, Department of Biological Sciences

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customized gene microarray approach for identifying leptin-regulated genes in human breast cancer. Leptin up-regulated many genes associated with cell cycle and proliferation, DNA synthesis, and ECM in Michigan Cancer Foundation-7 (MCF-7) cells. Expression of

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0215
Volume/Issue:
Volume 199: Issue 2
Free access
Feng-ying Gong Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 1# Shuai Fu Yuan Hu Tong, Dong Dan, Beijing 100730, China

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Yi-fan Shi Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 1# Shuai Fu Yuan Hu Tong, Dong Dan, Beijing 100730, China

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Jie-ying Deng Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 1# Shuai Fu Yuan Hu Tong, Dong Dan, Beijing 100730, China

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synthesis ( Gong et al. 2003 a , 2003 b , 2005 ). Furthermore, we also found the mechanism by which IFN-γ and IL-1β promoted GH-gene expression in rat pituitary GH3 cells may be different from the classical growth hormone-releasing hormone (GHRH

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06736
Volume/Issue:
Volume 190: Issue 2
Free access
Jui-Cheng Hsieh Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, Arizona 85004-2157, USA

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Rudolf C Estess Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, Arizona 85004-2157, USA

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Ichiro Kaneko Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, Arizona 85004-2157, USA
Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, Arizona 85004-2157, USA

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G Kerr Whitfield Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, Arizona 85004-2157, USA

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Peter W Jurutka Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, Arizona 85004-2157, USA
Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, Arizona 85004-2157, USA

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Mark R Haussler Department of Basic Medical Sciences, School of Mathematical and Natural Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, Arizona 85004-2157, USA

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have emerged from mouse gene knockout experiments, including a hairless gene ablation study by Thompson and colleagues ( Beaudoin et al . 2005 ) that showed an inverse relationship between the expression of hairless and sclerostin domain

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0212
Volume/Issue:
Volume 220: Issue 2
Free access
Richard R Almon Pharmaceutical Sciences, New York State Center of Excellence in Bioinformatics and Life Sciences, Departments of
Pharmaceutical Sciences, New York State Center of Excellence in Bioinformatics and Life Sciences, Departments of
Pharmaceutical Sciences, New York State Center of Excellence in Bioinformatics and Life Sciences, Departments of

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Debra C DuBois Pharmaceutical Sciences, New York State Center of Excellence in Bioinformatics and Life Sciences, Departments of
Pharmaceutical Sciences, New York State Center of Excellence in Bioinformatics and Life Sciences, Departments of

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William Lai Pharmaceutical Sciences, New York State Center of Excellence in Bioinformatics and Life Sciences, Departments of

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Bai Xue Pharmaceutical Sciences, New York State Center of Excellence in Bioinformatics and Life Sciences, Departments of

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Jing Nie Pharmaceutical Sciences, New York State Center of Excellence in Bioinformatics and Life Sciences, Departments of

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William J Jusko Pharmaceutical Sciences, New York State Center of Excellence in Bioinformatics and Life Sciences, Departments of
Pharmaceutical Sciences, New York State Center of Excellence in Bioinformatics and Life Sciences, Departments of

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factors such as fetal programming may contribute, major aspects of the development of type 2 diabetes appear to result from interactions between the expression and/or structure of multiple genes with environmental lifestyle factors. The hallmark of type 2

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0404
Volume/Issue:
Volume 200: Issue 3
Free access
Ola Nilsson Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA

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Elizabeth A Parker Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA

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Anita Hegde Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA

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Michael Chau Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA

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Kevin M Barnes Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA

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Jeffrey Baron Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA

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-quality RNA from the resting (RZ), proliferative (PZ), proliferative–hypertrophic transition zone, and hypertrophic zone (HZ) of 7-day-old male rats. Expression of approximately 29 000 genes was analyzed in each zone by microarray. This analysis

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.07099
Volume/Issue:
Volume 193: Issue 1
Free access