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Hyunju Chung Department of Pharmacology and Medical Research Center for Bioreaction to ROS and Biomedical Science Institute, Kyunghee University School of Medicine, Seoul 130-701, South Korea

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Sanghee Seo Department of Pharmacology and Medical Research Center for Bioreaction to ROS and Biomedical Science Institute, Kyunghee University School of Medicine, Seoul 130-701, South Korea

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Minho Moon Department of Pharmacology and Medical Research Center for Bioreaction to ROS and Biomedical Science Institute, Kyunghee University School of Medicine, Seoul 130-701, South Korea

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Seungjoon Park Department of Pharmacology and Medical Research Center for Bioreaction to ROS and Biomedical Science Institute, Kyunghee University School of Medicine, Seoul 130-701, South Korea

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endocrine pancreatic functions, carbohydrate metabolism, the cardiovascular system, gastric secretion, stomach motility, and sleep ( Van der Lely et al . 2004 , Ghigo et al . 2005 , Kojima & Kangawa 2005 ). Recently, we have reported that the acylated

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Sebastio Perrini Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Emergency and Organ Transplantation, University of Bari School of Medicine, Piazza Giulio Cesare, 11, I-70124 Bari, Italy

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Luigi Laviola Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Emergency and Organ Transplantation, University of Bari School of Medicine, Piazza Giulio Cesare, 11, I-70124 Bari, Italy

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Marcos C Carreira Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Emergency and Organ Transplantation, University of Bari School of Medicine, Piazza Giulio Cesare, 11, I-70124 Bari, Italy

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Angelo Cignarelli Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Emergency and Organ Transplantation, University of Bari School of Medicine, Piazza Giulio Cesare, 11, I-70124 Bari, Italy

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Annalisa Natalicchio Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Emergency and Organ Transplantation, University of Bari School of Medicine, Piazza Giulio Cesare, 11, I-70124 Bari, Italy

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Francesco Giorgino Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Emergency and Organ Transplantation, University of Bari School of Medicine, Piazza Giulio Cesare, 11, I-70124 Bari, Italy

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onset of slow-wave sleep and less conspicuous secretory episodes a few hours after meals ( Ho et al . 1988 , Hartman et al . 1991 ), and is controlled by the action of two hypothalamic factors, GHRH, which stimulates GH secretion, and somatostatin

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Marian Joëls Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center, Utrecht, The Netherlands
University of Groningen, University Medical Center, Groningen, The Netherlands

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E Ronald de Kloet Division of Endocrinology, Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands

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changes to hippocampal neuronal spines during the sleep–wake cycle received the Society for Endocrinology’s 2015 award for the best article published in Journal of Endocrinology ( Ikeda et al . 2015 ). In humans, dexamethasone reduced slow wave sleep

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A Cremades
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C Ruzafa
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F Monserrat
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A J López-Contreras
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R Peñafiel
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female mice, the variation of dietary arginine concentration did not significantly affect renal weight. Arginine deprivation also decreased renal ODC activity in the male mouse as well as the induction elicited by exogenous testosterone in the kidney of

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M Skrzypski Department of Animal Physiology and Biochemistry, Poznań University of Life Sciences, Poznań

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M Billert Department of Animal Physiology and Biochemistry, Poznań University of Life Sciences, Poznań

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K W Nowak Department of Animal Physiology and Biochemistry, Poznań University of Life Sciences, Poznań

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M Z Strowski Department of Hepatology and Gastroenterology & The Interdisciplinary Centre of Metabolism: Endocrinology, Diabetes and Metabolism, Charité-University Medicine Berlin, Berlin, Germany
Park-Klinik Weissensee, Internal Medicine – Gastroenterology, Berlin, Germany

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intake, energy expenditure ( Lubkin & Stricker-Krongrad 1998 , Sakurai et al . 1998 ) as well as by controlling sleep–waking cycle ( Lin et al . 1999 ). Animal studies in mice and dogs provided evidence that orexin deficiency or genetic inactivation of

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Hyunju Chung Department of Core Research Laboratory, Clinical Research Institute, Kyung Hee University Hospital at Gangdong, Seoul, Korea

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Seungjoon Park Department of Pharmacology and Medical Research Center for Bioreaction to ROS and Biomedical Science Institute, School of Medicine, Kyung Hee University, Seoul, Korea

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of physiological actions throughout the body, including effects on exocrine and endocrine pancreatic functions, carbohydrate metabolism, the cardiovascular system, gastric secretion, stomach motility and sleep ( Van der Lely et al. 2004 , Ghigo et

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Hyunju Chung
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Endan Li Department of Core Research Laboratory, Department of Pharmacology and Medical Research Center for Bioreaction to ROS and Biomedical Science Institute, Clinical Research Institute, Kyung Hee University Hospital at Gangdong, Seoul, Korea

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Yumi Kim Department of Core Research Laboratory, Department of Pharmacology and Medical Research Center for Bioreaction to ROS and Biomedical Science Institute, Clinical Research Institute, Kyung Hee University Hospital at Gangdong, Seoul, Korea

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Sehee Kim Department of Core Research Laboratory, Department of Pharmacology and Medical Research Center for Bioreaction to ROS and Biomedical Science Institute, Clinical Research Institute, Kyung Hee University Hospital at Gangdong, Seoul, Korea

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Seungjoon Park Department of Core Research Laboratory, Department of Pharmacology and Medical Research Center for Bioreaction to ROS and Biomedical Science Institute, Clinical Research Institute, Kyung Hee University Hospital at Gangdong, Seoul, Korea

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effects on exocrine and endocrine pancreatic functions, carbohydrate metabolism, the cardiovascular system, gastric secretion, stomach motility, and sleep ( Van der Lely et al . 2004 , Ghigo et al . 2005 , Kojima & Kangawa 2005 ). Numerous studies have

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Anneleen Segers Translational Research Center for Gastrointestinal Disorders, KU Leuven, Leuven, Belgium

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Louis Desmet Translational Research Center for Gastrointestinal Disorders, KU Leuven, Leuven, Belgium

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Shu Sun Translational Research Center for Gastrointestinal Disorders, KU Leuven, Leuven, Belgium

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Kristin Verbeke Translational Research Center for Gastrointestinal Disorders, KU Leuven, Leuven, Belgium

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Jan Tack Translational Research Center for Gastrointestinal Disorders, KU Leuven, Leuven, Belgium

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Inge Depoortere Translational Research Center for Gastrointestinal Disorders, KU Leuven, Leuven, Belgium

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Obal F Jr Krueger JM 2004 Rhythms of ghrelin, leptin, and sleep in rats: effects of the normal diurnal cycle, restricted feeding, and sleep deprivation . American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 287 R

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Isao Tamura Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Ube, Japan

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Hiroshi Tamura Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Ube, Japan

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Mai Kawamoto-Jozaki Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Ube, Japan

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Yumiko Doi-Tanaka Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Ube, Japan

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Haruka Takagi Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Ube, Japan

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Yuichiro Shirafuta Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Ube, Japan

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Yumiko Mihara Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Ube, Japan

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Ryo Maekawa Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Ube, Japan

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Toshiaki Taketani Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Ube, Japan

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Shun Sato Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Ube, Japan

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Norihiro Sugino Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Ube, Japan

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representative ketone bodies that increases under starvation ( Cahill 2006 ). 3-HBA and its related metabolites were not upregulated by melatonin treatment, suggesting that melatonin treatment did not cause excessive energy deprivation or a disordering of energy

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Taira Wada Laboratory of Health Science, School of Pharmacy, Nihon University, Funabshi, Chiba, Japan

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Yukiko Yamamoto Laboratory of Health Science, School of Pharmacy, Nihon University, Funabshi, Chiba, Japan

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Yukiko Takasugi Laboratory of Health Science, School of Pharmacy, Nihon University, Funabshi, Chiba, Japan

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Hirotake Ishii Laboratory of Health Science, School of Pharmacy, Nihon University, Funabshi, Chiba, Japan

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Taketo Uchiyama Laboratory of Organic Chemistry, School of Pharmacy, Nihon University, Funabshi, Chiba, Japan

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Kaori Saitoh Department of Psychiatry, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan

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Masahiro Suzuki Department of Psychiatry, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan

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Makoto Uchiyama Department of Psychiatry, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan
Tokyo Adachi Hospital, Adachi, Tokyo, Japan

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Hikari Yoshitane Department of Biological Sciences, School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

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Yoshitaka Fukada Department of Biological Sciences, School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

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Shigeki Shimba Laboratory of Health Science, School of Pharmacy, Nihon University, Funabshi, Chiba, Japan

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.bbrc.2005.02.081 ) 10.1016/j.bbrc.2005.02.081 25821984 Bodosi B Gardi J Hajdu I Szentirmai E Obal Jr F Krueger JM 2004 Rhythms of ghrelin, leptin, and sleep in rats: effects of the normal diurnal cycle, restricted feeding, and sleep deprivation

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