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endocrine pancreatic functions, carbohydrate metabolism, the cardiovascular system, gastric secretion, stomach motility, and sleep ( Van der Lely et al . 2004 , Ghigo et al . 2005 , Kojima & Kangawa 2005 ). Recently, we have reported that the acylated
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onset of slow-wave sleep and less conspicuous secretory episodes a few hours after meals ( Ho et al . 1988 , Hartman et al . 1991 ), and is controlled by the action of two hypothalamic factors, GHRH, which stimulates GH secretion, and somatostatin
University of Groningen, University Medical Center, Groningen, The Netherlands
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changes to hippocampal neuronal spines during the sleep–wake cycle received the Society for Endocrinology’s 2015 award for the best article published in Journal of Endocrinology ( Ikeda et al . 2015 ). In humans, dexamethasone reduced slow wave sleep
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female mice, the variation of dietary arginine concentration did not significantly affect renal weight. Arginine deprivation also decreased renal ODC activity in the male mouse as well as the induction elicited by exogenous testosterone in the kidney of
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intake, energy expenditure ( Lubkin & Stricker-Krongrad 1998 , Sakurai et al . 1998 ) as well as by controlling sleep–waking cycle ( Lin et al . 1999 ). Animal studies in mice and dogs provided evidence that orexin deficiency or genetic inactivation of
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of physiological actions throughout the body, including effects on exocrine and endocrine pancreatic functions, carbohydrate metabolism, the cardiovascular system, gastric secretion, stomach motility and sleep ( Van der Lely et al. 2004 , Ghigo et
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effects on exocrine and endocrine pancreatic functions, carbohydrate metabolism, the cardiovascular system, gastric secretion, stomach motility, and sleep ( Van der Lely et al . 2004 , Ghigo et al . 2005 , Kojima & Kangawa 2005 ). Numerous studies have
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Obal F Jr Krueger JM 2004 Rhythms of ghrelin, leptin, and sleep in rats: effects of the normal diurnal cycle, restricted feeding, and sleep deprivation . American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 287 R
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representative ketone bodies that increases under starvation ( Cahill 2006 ). 3-HBA and its related metabolites were not upregulated by melatonin treatment, suggesting that melatonin treatment did not cause excessive energy deprivation or a disordering of energy
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.bbrc.2005.02.081 ) 10.1016/j.bbrc.2005.02.081 25821984 Bodosi B Gardi J Hajdu I Szentirmai E Obal Jr F Krueger JM 2004 Rhythms of ghrelin, leptin, and sleep in rats: effects of the normal diurnal cycle, restricted feeding, and sleep deprivation