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A Makker
A Makker
Division of Endocrinology, Central Drug Research Institute, Lucknow-226 001, India
Division of Parasitology, Central Drug Research Institute, Lucknow, India
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Division of Parasitology, Central Drug Research Institute, Lucknow, India
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F W Bansode
F W Bansode
Division of Endocrinology, Central Drug Research Institute, Lucknow-226 001, India
Division of Parasitology, Central Drug Research Institute, Lucknow, India
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Division of Parasitology, Central Drug Research Institute, Lucknow, India
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V M L Srivastava
V M L Srivastava
Division of Endocrinology, Central Drug Research Institute, Lucknow-226 001, India
Division of Parasitology, Central Drug Research Institute, Lucknow, India
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Division of Parasitology, Central Drug Research Institute, Lucknow, India
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M M Singh
M M Singh
Division of Endocrinology, Central Drug Research Institute, Lucknow-226 001, India
Division of Parasitology, Central Drug Research Institute, Lucknow, India
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Division of Parasitology, Central Drug Research Institute, Lucknow, India
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antioxidant defense system (see later Materials and Methods Section I) and uterine responsiveness to deciduogenic stimulus using uterine weight, histology, histomorphometry and ornithine decarboxylase (ODC) activity (a marker of tissue growth and repair
Shoshana Yakar
Shoshana Yakar
National Institute of Diabetes, Digestive and Kidney Diseases, Bethesda, Maryland, USA
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Mary L Bouxsein
Mary L Bouxsein
National Institute of Diabetes, Digestive and Kidney Diseases, Bethesda, Maryland, USA
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Ernesto Canalis
Ernesto Canalis
National Institute of Diabetes, Digestive and Kidney Diseases, Bethesda, Maryland, USA
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Hui Sun
Hui Sun
National Institute of Diabetes, Digestive and Kidney Diseases, Bethesda, Maryland, USA
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Vaida Glatt
Vaida Glatt
National Institute of Diabetes, Digestive and Kidney Diseases, Bethesda, Maryland, USA
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Caren Gundberg
Caren Gundberg
National Institute of Diabetes, Digestive and Kidney Diseases, Bethesda, Maryland, USA
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Pinchas Cohen
Pinchas Cohen
National Institute of Diabetes, Digestive and Kidney Diseases, Bethesda, Maryland, USA
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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David Hwang
David Hwang
National Institute of Diabetes, Digestive and Kidney Diseases, Bethesda, Maryland, USA
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Yves Boisclair
Yves Boisclair
National Institute of Diabetes, Digestive and Kidney Diseases, Bethesda, Maryland, USA
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Derek LeRoith
Derek LeRoith
National Institute of Diabetes, Digestive and Kidney Diseases, Bethesda, Maryland, USA
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Clifford J Rosen
Clifford J Rosen
National Institute of Diabetes, Digestive and Kidney Diseases, Bethesda, Maryland, USA
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Yale University School of Medicine, New Haven, Connecticut, USA
Mattel Hospital for Children, Los Angeles California, USA
The Department of Animal Science, Cornell University, Ithaca, New York, USA
The Jackson Laboratory, Bar Harbor, Maine, USA
Maine Center for Osteoporosis Research and Education, St Joseph Hospital, Maine, USA
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-computed tomography (μCT) and histomorphometry. All procedures were approved by the Animal Care and Use Committee of the National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Health, Bethesda, MD, USA
A Iida-Klein
A Iida-Klein
Regional Bone and
Clinical Research Centers, Helen Hayes Hospital, West Haverstraw, New York, USA
Scanco USA Inc., Wayne, Pennsylvania, USA
Departments of Clinical Pathology and
Medicine, Columbia University, College of Physicians and Surgeons, New York, New York, USA
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Clinical Research Centers, Helen Hayes Hospital, West Haverstraw, New York, USA
Scanco USA Inc., Wayne, Pennsylvania, USA
Departments of Clinical Pathology and
Medicine, Columbia University, College of Physicians and Surgeons, New York, New York, USA
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S Shou Lu
S Shou Lu
Regional Bone and
Clinical Research Centers, Helen Hayes Hospital, West Haverstraw, New York, USA
Scanco USA Inc., Wayne, Pennsylvania, USA
Departments of Clinical Pathology and
Medicine, Columbia University, College of Physicians and Surgeons, New York, New York, USA
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Clinical Research Centers, Helen Hayes Hospital, West Haverstraw, New York, USA
Scanco USA Inc., Wayne, Pennsylvania, USA
Departments of Clinical Pathology and
Medicine, Columbia University, College of Physicians and Surgeons, New York, New York, USA
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R Kapadia
R Kapadia
Regional Bone and
Clinical Research Centers, Helen Hayes Hospital, West Haverstraw, New York, USA
Scanco USA Inc., Wayne, Pennsylvania, USA
Departments of Clinical Pathology and
Medicine, Columbia University, College of Physicians and Surgeons, New York, New York, USA
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Clinical Research Centers, Helen Hayes Hospital, West Haverstraw, New York, USA
Scanco USA Inc., Wayne, Pennsylvania, USA
Departments of Clinical Pathology and
Medicine, Columbia University, College of Physicians and Surgeons, New York, New York, USA
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M Burkhart
M Burkhart
Regional Bone and
Clinical Research Centers, Helen Hayes Hospital, West Haverstraw, New York, USA
Scanco USA Inc., Wayne, Pennsylvania, USA
Departments of Clinical Pathology and
Medicine, Columbia University, College of Physicians and Surgeons, New York, New York, USA
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Clinical Research Centers, Helen Hayes Hospital, West Haverstraw, New York, USA
Scanco USA Inc., Wayne, Pennsylvania, USA
Departments of Clinical Pathology and
Medicine, Columbia University, College of Physicians and Surgeons, New York, New York, USA
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A Moreno
A Moreno
Regional Bone and
Clinical Research Centers, Helen Hayes Hospital, West Haverstraw, New York, USA
Scanco USA Inc., Wayne, Pennsylvania, USA
Departments of Clinical Pathology and
Medicine, Columbia University, College of Physicians and Surgeons, New York, New York, USA
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Clinical Research Centers, Helen Hayes Hospital, West Haverstraw, New York, USA
Scanco USA Inc., Wayne, Pennsylvania, USA
Departments of Clinical Pathology and
Medicine, Columbia University, College of Physicians and Surgeons, New York, New York, USA
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D W Dempster
D W Dempster
Regional Bone and
Clinical Research Centers, Helen Hayes Hospital, West Haverstraw, New York, USA
Scanco USA Inc., Wayne, Pennsylvania, USA
Departments of Clinical Pathology and
Medicine, Columbia University, College of Physicians and Surgeons, New York, New York, USA
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Clinical Research Centers, Helen Hayes Hospital, West Haverstraw, New York, USA
Scanco USA Inc., Wayne, Pennsylvania, USA
Departments of Clinical Pathology and
Medicine, Columbia University, College of Physicians and Surgeons, New York, New York, USA
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R Lindsay
R Lindsay
Regional Bone and
Clinical Research Centers, Helen Hayes Hospital, West Haverstraw, New York, USA
Scanco USA Inc., Wayne, Pennsylvania, USA
Departments of Clinical Pathology and
Medicine, Columbia University, College of Physicians and Surgeons, New York, New York, USA
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Clinical Research Centers, Helen Hayes Hospital, West Haverstraw, New York, USA
Scanco USA Inc., Wayne, Pennsylvania, USA
Departments of Clinical Pathology and
Medicine, Columbia University, College of Physicians and Surgeons, New York, New York, USA
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dynamic histomorphometry and vitamin D status. However, the current study clearly demonstrated the feasibility of this approach, and indicated that short-term infusion with hPTH1–34 might hold significant promise as a murine model to study the cellular and
Yongmei Wang
Yongmei Wang
Department of Medicine, Endocrine Unit, Veterans Affairs Medical Center, University of California, San Francisco, California 94117-1080, USA
Department of Radiology, University of California, San Francisco, California 94117-1080, USA
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Department of Radiology, University of California, San Francisco, California 94117-1080, USA
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Takeshi Sakata
Takeshi Sakata
Department of Medicine, Endocrine Unit, Veterans Affairs Medical Center, University of California, San Francisco, California 94117-1080, USA
Department of Radiology, University of California, San Francisco, California 94117-1080, USA
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Department of Radiology, University of California, San Francisco, California 94117-1080, USA
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Hashem Z Elalieh
Hashem Z Elalieh
Department of Medicine, Endocrine Unit, Veterans Affairs Medical Center, University of California, San Francisco, California 94117-1080, USA
Department of Radiology, University of California, San Francisco, California 94117-1080, USA
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Department of Radiology, University of California, San Francisco, California 94117-1080, USA
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Scott J Munson
Scott J Munson
Department of Medicine, Endocrine Unit, Veterans Affairs Medical Center, University of California, San Francisco, California 94117-1080, USA
Department of Radiology, University of California, San Francisco, California 94117-1080, USA
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Department of Radiology, University of California, San Francisco, California 94117-1080, USA
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Andrew Burghardt
Andrew Burghardt
Department of Medicine, Endocrine Unit, Veterans Affairs Medical Center, University of California, San Francisco, California 94117-1080, USA
Department of Radiology, University of California, San Francisco, California 94117-1080, USA
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Department of Radiology, University of California, San Francisco, California 94117-1080, USA
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Sharmila Majumdar
Sharmila Majumdar
Department of Medicine, Endocrine Unit, Veterans Affairs Medical Center, University of California, San Francisco, California 94117-1080, USA
Department of Radiology, University of California, San Francisco, California 94117-1080, USA
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Department of Radiology, University of California, San Francisco, California 94117-1080, USA
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Bernard P Halloran
Bernard P Halloran
Department of Medicine, Endocrine Unit, Veterans Affairs Medical Center, University of California, San Francisco, California 94117-1080, USA
Department of Radiology, University of California, San Francisco, California 94117-1080, USA
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Department of Radiology, University of California, San Francisco, California 94117-1080, USA
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Daniel D Bikle
Daniel D Bikle
Department of Medicine, Endocrine Unit, Veterans Affairs Medical Center, University of California, San Francisco, California 94117-1080, USA
Department of Radiology, University of California, San Francisco, California 94117-1080, USA
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Department of Radiology, University of California, San Francisco, California 94117-1080, USA
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by assessing fat free weight (FFW), structure by micro computed tomography (μCT), bone histomorphometry, colony forming units in bone marrow stromal cell (BMSC) cultures, and mRNA levels of resorption and formation markers using quantitative real
Therese Standal
Therese Standal
St.Vincent's Institute of Medical Research, Department of Medicine at St. Vincent's Hospital Melbourne, Department of Cancer Research and Molecular Medicine, 9 Princes St, Fitzroy, Victoria 3065, Australia
St.Vincent's Institute of Medical Research, Department of Medicine at St. Vincent's Hospital Melbourne, Department of Cancer Research and Molecular Medicine, 9 Princes St, Fitzroy, Victoria 3065, Australia
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St.Vincent's Institute of Medical Research, Department of Medicine at St. Vincent's Hospital Melbourne, Department of Cancer Research and Molecular Medicine, 9 Princes St, Fitzroy, Victoria 3065, Australia
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Rachelle W Johnson
Rachelle W Johnson
St.Vincent's Institute of Medical Research, Department of Medicine at St. Vincent's Hospital Melbourne, Department of Cancer Research and Molecular Medicine, 9 Princes St, Fitzroy, Victoria 3065, Australia
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Narelle E McGregor
Narelle E McGregor
St.Vincent's Institute of Medical Research, Department of Medicine at St. Vincent's Hospital Melbourne, Department of Cancer Research and Molecular Medicine, 9 Princes St, Fitzroy, Victoria 3065, Australia
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Ingrid J Poulton
Ingrid J Poulton
St.Vincent's Institute of Medical Research, Department of Medicine at St. Vincent's Hospital Melbourne, Department of Cancer Research and Molecular Medicine, 9 Princes St, Fitzroy, Victoria 3065, Australia
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Patricia W M Ho
Patricia W M Ho
St.Vincent's Institute of Medical Research, Department of Medicine at St. Vincent's Hospital Melbourne, Department of Cancer Research and Molecular Medicine, 9 Princes St, Fitzroy, Victoria 3065, Australia
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T John Martin
T John Martin
St.Vincent's Institute of Medical Research, Department of Medicine at St. Vincent's Hospital Melbourne, Department of Cancer Research and Molecular Medicine, 9 Princes St, Fitzroy, Victoria 3065, Australia
St.Vincent's Institute of Medical Research, Department of Medicine at St. Vincent's Hospital Melbourne, Department of Cancer Research and Molecular Medicine, 9 Princes St, Fitzroy, Victoria 3065, Australia
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St.Vincent's Institute of Medical Research, Department of Medicine at St. Vincent's Hospital Melbourne, Department of Cancer Research and Molecular Medicine, 9 Princes St, Fitzroy, Victoria 3065, Australia
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Natalie A Sims
Natalie A Sims
St.Vincent's Institute of Medical Research, Department of Medicine at St. Vincent's Hospital Melbourne, Department of Cancer Research and Molecular Medicine, 9 Princes St, Fitzroy, Victoria 3065, Australia
St.Vincent's Institute of Medical Research, Department of Medicine at St. Vincent's Hospital Melbourne, Department of Cancer Research and Molecular Medicine, 9 Princes St, Fitzroy, Victoria 3065, Australia
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St.Vincent's Institute of Medical Research, Department of Medicine at St. Vincent's Hospital Melbourne, Department of Cancer Research and Molecular Medicine, 9 Princes St, Fitzroy, Victoria 3065, Australia
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( Sims et al . 2006 ). Briefly, trabecular histomorphometry was carried out on undecalcified sections in the secondary spongiosa of the proximal tibia, in a region 370 μm below the proximal edge of the hypertrophic zone of the growth plate, extending 1
Richard Eastell
Richard Eastell
Academic Unit of Bone Metabolism, Division of Clinical Sciences (North), School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield, UK
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in the rate of clearance from the circulation. The alternative methods for studying bone turnover include bone histomorphometry, calcium balance with kinetics, and radioisotope tracer methods. Bone histomorphometry is based on a bone biopsy
Kenneth A Philbrick
Kenneth A Philbrick
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Stephen A Martin
Stephen A Martin
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Amy R Colagiovanni
Amy R Colagiovanni
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Adam J Branscum
Adam J Branscum
Biostatistics Program, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Russell T Turner
Russell T Turner
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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Urszula T Iwaniec
Urszula T Iwaniec
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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(osteoblast perimeter/bone perimeter, %) were also determined in the epiphysis. Measurements were performed at either 20 or 40× using the Osteomeasure Histomorphometry System (Osteometrics, Atlanta, GA, USA). Histomorphometric data are reported using standard
Saranyapin Potikanond
Saranyapin Potikanond
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Pinyada Rattanachote
Pinyada Rattanachote
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Hiranya Pintana
Hiranya Pintana
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Panan Suntornsaratoon
Panan Suntornsaratoon
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Narattaphol Charoenphandhu
Narattaphol Charoenphandhu
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Nipon Chattipakorn
Nipon Chattipakorn
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Siriporn Chattipakorn
Siriporn Chattipakorn
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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experiment, animals were deeply anesthetized and sacrificed. The tibiae were removed, cleaned, and kept with in normal saline at −80 °C before micro-computed tomography (micro-CT) and histomorphometry analysis. Also, total visceral fat, including peritoneal
Kenneth A Philbrick
Kenneth A Philbrick
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Carmen P Wong
Carmen P Wong
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Adam J Branscum
Adam J Branscum
Biostatistics Program, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Russell T Turner
Russell T Turner
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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Urszula T Iwaniec
Urszula T Iwaniec
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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femur metaphysis. Direct cancellous bone measurements included cancellous bone volume fraction (bone volume/tissue volume, %), trabecular number (mm −1 ) and trabecular thickness (µm). Histomorphometry The methods used to measure longitudinal
Helen E MacLean
Helen E MacLean
Department of Medicine, Hanson Institute, Department of Endocrinology, ANZAC Research Institute, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia
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Alison J Moore
Alison J Moore
Department of Medicine, Hanson Institute, Department of Endocrinology, ANZAC Research Institute, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia
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Stephen A Sastra
Stephen A Sastra
Department of Medicine, Hanson Institute, Department of Endocrinology, ANZAC Research Institute, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia
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Howard A Morris
Howard A Morris
Department of Medicine, Hanson Institute, Department of Endocrinology, ANZAC Research Institute, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia
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Ali Ghasem-Zadeh
Ali Ghasem-Zadeh
Department of Medicine, Hanson Institute, Department of Endocrinology, ANZAC Research Institute, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia
Department of Medicine, Hanson Institute, Department of Endocrinology, ANZAC Research Institute, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia
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Department of Medicine, Hanson Institute, Department of Endocrinology, ANZAC Research Institute, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia
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Kesha Rana
Kesha Rana
Department of Medicine, Hanson Institute, Department of Endocrinology, ANZAC Research Institute, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia
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Anna-Maree Axell
Anna-Maree Axell
Department of Medicine, Hanson Institute, Department of Endocrinology, ANZAC Research Institute, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia
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Amanda J Notini
Amanda J Notini
Department of Medicine, Hanson Institute, Department of Endocrinology, ANZAC Research Institute, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia
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David J Handelsman
David J Handelsman
Department of Medicine, Hanson Institute, Department of Endocrinology, ANZAC Research Institute, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia
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Ego Seeman
Ego Seeman
Department of Medicine, Hanson Institute, Department of Endocrinology, ANZAC Research Institute, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia
Department of Medicine, Hanson Institute, Department of Endocrinology, ANZAC Research Institute, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia
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Department of Medicine, Hanson Institute, Department of Endocrinology, ANZAC Research Institute, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia
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Jeffrey D Zajac
Jeffrey D Zajac
Department of Medicine, Hanson Institute, Department of Endocrinology, ANZAC Research Institute, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia
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Rachel A Davey
Rachel A Davey
Department of Medicine, Hanson Institute, Department of Endocrinology, ANZAC Research Institute, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia
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accepted standards of humane animal care, and performed with the approval of the Austin Health Animal Ethics Committee. Tissue collection and serum analysis Adult mice were studied at 9 weeks of age. For dynamic bone histomorphometry experiments, mice
