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Department of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, Texas, USA
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Department of Cell and Microbiology, Weill Cornell Medical College, New York, New York, USA
Department of Genetics, The University of Texas Anderson Cancer Center, Houston, Texas, USA
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Department of Molecular Physiology & Biophysics, Baylor College of Medicine, Houston, Texas, USA
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Department of Cell and Microbiology, Weill Cornell Medical College, New York, New York, USA
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Introduction The confluence of factors that characterize metabolic syndrome (MetS) are prevalent in the Western world and includes hypertension, abdominal obesity, elevated fasting glucose, insulin resistance (IR), elevated blood triglycerides
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resistance and an altered lipid profile) are similar to those of metabolic syndrome ( Moura et al . 2009 ). More recently, we obtained a similar profile in adult animals with a non-pharmacological model where a maternal bandage was used to cover the teats of
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School of Population Health, Curtin University, Perth, Australia
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dysfunction. One increasingly important example of metabolic dysfunction is metabolic syndrome, a cluster of conditions (high blood pressure, high blood glucose, abdominal adiposity and hyperlipidaemia) that increase the risk of heart disease, stroke and
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Introduction Obesity and insulin resistance are at the centre of the metabolic syndrome which is a major risk factor for the development of cardiovascular disease. There is growing evidence for an implication of adipose dysfunction critically
Key Laboratory for Atherosclerology of Hunan Province, Department of Nutrition and Metabolism, Clinical Research Center for Diabetes, Institute of Cardiovascular Research, Life Science Research Center, University of South China, Hengyang, Hunan 421001, People's Republic of China
Key Laboratory for Atherosclerology of Hunan Province, Department of Nutrition and Metabolism, Clinical Research Center for Diabetes, Institute of Cardiovascular Research, Life Science Research Center, University of South China, Hengyang, Hunan 421001, People's Republic of China
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Introduction The metabolic syndrome (syndrome X) refers to the aggregation of a cluster of risk factors, including insulin resistance/hyperinsulinemia and dyslipidemia (increased low-density lipoprotein cholesterol (LDL-C), and depressed high
Division of Pulmonary, Medicine, Pathology, Pathology, CVGI Discovery, Diabetes Drug Discovery, Allergy, and Critical Care Medicine, Vascular Medicine Institute, Departments of
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Division of Pulmonary, Medicine, Pathology, Pathology, CVGI Discovery, Diabetes Drug Discovery, Allergy, and Critical Care Medicine, Vascular Medicine Institute, Departments of
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Division of Pulmonary, Medicine, Pathology, Pathology, CVGI Discovery, Diabetes Drug Discovery, Allergy, and Critical Care Medicine, Vascular Medicine Institute, Departments of
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pathways of DN to be identified, it does not share primary features of metabolic syndrome: insulin resistance/hyperinsulinemia, obesity, and hypertension. Furthermore, STZ rats develop mild hyperlipidemia and are resistant to development of nephropathy
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with the Tukey’s honestly significant difference correction. Data are reported as mean±1 s.e.m. Results TMEM18 appears to regulate metabolic syndrome via effects on insulin To find clues for TMEM18 ’s relationship with obesity, we
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current knowledge of the metabolic and vascular actions of testosterone in these disorders – specifically, how testosterone deficiency contributes to insulin resistance, metabolic syndrome, type 2 diabetes ( Kelly & Jones 2013 a ), and cardiovascular
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nutrition) have been shown to interact (including through metabolic syndrome, MetS) and contribute to CVD. White adipose tissue (WAT) has been identified as a metabolically active endocrine organ that affects a plethora of body functions including energy and
Department of Medicine Austin Health, Department of Endocrinology, University of Melbourne, 145 Studley Road, Heidelberg, Victoria 3084, Australia
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for the large proportion of men with metabolic disorders, defined here as type 2 diabetes and or the metabolic syndrome, but without clear-cut classical hypogonadism, is not known. This is because we have insufficient evidence to conclusively answer