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Department of Biochemistry, Microbiology and Immunology, The University of Ottawa, Faculty of Medicine, Ottawa, Ontario, Canada
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Department of Biochemistry, Microbiology and Immunology, The University of Ottawa, Faculty of Medicine, Ottawa, Ontario, Canada
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by leading to more significant weight loss, a greater percentage of individuals attaining weight loss, further lowering lipid levels, improving T2DM management, and enhancing overall substrate metabolism compared to the use of GLP-1R agonists alone
Pinnacle Clinical Research, Live Oak, USA
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Baylor College of Medicine, Houston, USA
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of the obesity-associated diseases that can cause serious health problems ( Wilson et al. 2002 , Bhaskaran et al. 2014 ). Although disturbing physiological metabolism and exacerbating other metabolic problems, these obesity-associated diseases
Nottingham Digestive Disease Centre and Biomedical Research Centre, School of Medicine, University of Nottingham, Nottingham, UK
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Introduction Although brown adipose tissue (BAT) may be one of the smallest fat depots in the adult, it has the potential to have a substantial influence on energy balance, as well as glucose and lipid metabolism ( Cannon & Nedergaard 2012 b
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wall of the third ventricle ( Szilvasy-Szabo et al. 2017 ). Tanycytes, via a CX43-dependent mechanism, supply lactate to ARH POMC neurons, regulating feeding behavior and energy metabolism ( Lhomme et al. 2021 ). A recent study revealed that
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metabolic outcomes. Here, we hypothesized that the desynchronization of circadian rhythm could be a risk factor of the onset of cardiometabolic disorders associated with disruptions of the hypothalamic–pituitary–adrenal axis and liver metabolism. In this way
Faculty of Dentistry, McGill University, Montreal, Quebec, Canada
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Département de Mathématiques, Université du Québec à Montréal, Montréal, Québec, Canada
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Départements de Médecine et de Biochimie et Médecine Moléculaire, Université de Montréal, Montréal, Québec, Canada
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Faculty of Dentistry, McGill University, Montreal, Quebec, Canada
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undercarboxylated form ( Ferron et al . 2010 a , 2015 , Lacombe et al . 2013 ). OCN influences glucose metabolism through regulation of both insulin secretion and sensitivity ( Lee et al . 2007 , Ferron et al . 2008 ). OCN leads to decrease in adiposity and
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factors on the maternal and infant microbiota. Maternal factors significantly contribute to the initial colonization and succession of the infant gut microbiota. Alterations in this process may have long-term health consequences related to host metabolism
East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, North Carolina, USA
Human Performance Laboratory, College of Health and Human Performance, East Carolina University, Greenville, North Carolina, USA
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Human Performance Laboratory, College of Health and Human Performance, East Carolina University, Greenville, North Carolina, USA
Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA
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Human Performance Laboratory, College of Health and Human Performance, East Carolina University, Greenville, North Carolina, USA
Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA
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Human Performance Laboratory, College of Health and Human Performance, East Carolina University, Greenville, North Carolina, USA
Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA
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Human Performance Laboratory, College of Health and Human Performance, East Carolina University, Greenville, North Carolina, USA
Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA
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Human Performance Laboratory, College of Health and Human Performance, East Carolina University, Greenville, North Carolina, USA
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Human Performance Laboratory, College of Health and Human Performance, East Carolina University, Greenville, North Carolina, USA
Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA
Department of Physiology, East Carolina University, Greenville, North Carolina, USA
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Metabolic Hormone Magnetic Bead Panel – Metabolism Multiplex Assay (MMHMAG-44K, Millipore). Serum triglycerides level was measured with Triglyceride Assay Kit (ab65336, Abcam). Determination of insulin resistance by homeostasis model assessment of
Leibniz Institute for Resilience Research (LIR), Mainz, Germany
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Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
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Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
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Leibniz Institute for Resilience Research (LIR), Mainz, Germany
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Leibniz Institute for Resilience Research (LIR), Mainz, Germany
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metabolic disorders ( Scott et al. 2012 ). Thus, understanding how chronic stress affects metabolism represents an important research question in biomedical sciences that remains to be fully addressed. Chronic stress challenges homeostatic processes with
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Introduction Homoeostatic regulation of fuel metabolism in the body is a tightly controlled process and dysregulation can lead to pathological conditions such as diabetes mellitus (DM), cardiovascular disease, stroke, renal disease and other