Search Results

You are looking at 31 - 40 of 1,205 items for :

  • "transcription factor" x
  • Refine by access: All content x
Clear All
Koen D Flach Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

Search for other papers by Koen D Flach in
Google Scholar
PubMed
Close
and
Wilbert Zwart Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

Search for other papers by Wilbert Zwart in
Google Scholar
PubMed
Close

this disease every year ( Ferlay et al. 2015 ). Approximately 70% of breast tumors are estrogen receptor α (ERα) positive, and tumor cell proliferation is thought to be dependent on the activity of this hormone-mediated transcription factor ( Hayashi

Free access
Abdullah Cim
Search for other papers by Abdullah Cim in
Google Scholar
PubMed
Close
,
Greta J Sawyer
Search for other papers by Greta J Sawyer in
Google Scholar
PubMed
Close
,
Xiaohong Zhang
Search for other papers by Xiaohong Zhang in
Google Scholar
PubMed
Close
,
Haibin Su
Search for other papers by Haibin Su in
Google Scholar
PubMed
Close
,
Louise Collins
Search for other papers by Louise Collins in
Google Scholar
PubMed
Close
,
Peter Jones Department of Hepatology and Transplantation, Diabetes Research Group, Department of Medical and Molecular Genetics, InvivoGen, Institut für Zellbiologie, King's College London School of Medicine, James Black Centre, 125 Coldharbour Lane, London SE5 9NU, UK

Search for other papers by Peter Jones in
Google Scholar
PubMed
Close
,
Michael Antoniou Department of Hepatology and Transplantation, Diabetes Research Group, Department of Medical and Molecular Genetics, InvivoGen, Institut für Zellbiologie, King's College London School of Medicine, James Black Centre, 125 Coldharbour Lane, London SE5 9NU, UK

Search for other papers by Michael Antoniou in
Google Scholar
PubMed
Close
,
Jean-Paul Reynes Department of Hepatology and Transplantation, Diabetes Research Group, Department of Medical and Molecular Genetics, InvivoGen, Institut für Zellbiologie, King's College London School of Medicine, James Black Centre, 125 Coldharbour Lane, London SE5 9NU, UK

Search for other papers by Jean-Paul Reynes in
Google Scholar
PubMed
Close
,
Hans-Joachim Lipps Department of Hepatology and Transplantation, Diabetes Research Group, Department of Medical and Molecular Genetics, InvivoGen, Institut für Zellbiologie, King's College London School of Medicine, James Black Centre, 125 Coldharbour Lane, London SE5 9NU, UK

Search for other papers by Hans-Joachim Lipps in
Google Scholar
PubMed
Close
, and
John W Fabre
Search for other papers by John W Fabre in
Google Scholar
PubMed
Close

factor NeuroD1 avoided exocrine transdifferentiation ( Kojima et al . 2003 ). More recently, transdifferentiation to insulin-producing cells, without exocrine differentiation, has been achieved in mice with adenovirus delivery of multiple transcription

Free access
Brad G Hoffman
Search for other papers by Brad G Hoffman in
Google Scholar
PubMed
Close
and
Steven J M Jones Department of Cancer Endocrinology, Micheal Smith Genome Sciences Centre, BC Cancer Research Center, 675 West 10th Avenue, Vancouver, BC, Canada V5Z 1L3

Search for other papers by Steven J M Jones in
Google Scholar
PubMed
Close

Introduction The transcriptional networks driving mammalian cell development and function are only beginning to be elucidated. In many tissues transcription factors critical to normal development and function have been identified but, in general

Free access
Isabella Artner Cell and Developmental Biology, Departments of

Search for other papers by Isabella Artner in
Google Scholar
PubMed
Close
,
Yan Hang Cell and Developmental Biology, Departments of

Search for other papers by Yan Hang in
Google Scholar
PubMed
Close
,
Min Guo Cell and Developmental Biology, Departments of

Search for other papers by Min Guo in
Google Scholar
PubMed
Close
,
Guoqiang Gu Cell and Developmental Biology, Departments of

Search for other papers by Guoqiang Gu in
Google Scholar
PubMed
Close
, and
Roland Stein Cell and Developmental Biology, Departments of
Cell and Developmental Biology, Departments of

Search for other papers by Roland Stein in
Google Scholar
PubMed
Close

target genes required for proper islet cell function. MafA and MafB were only recently linked to Insulin and Glucagon expression and represent the principal members of the large Maf transcription factor family expressed in the pancreas ( Olbrot et al

Free access
R C M Simmen Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA
Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA
Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA

Search for other papers by R C M Simmen in
Google Scholar
PubMed
Close
,
J M P Pabona Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA

Search for other papers by J M P Pabona in
Google Scholar
PubMed
Close
,
M C Velarde Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA

Search for other papers by M C Velarde in
Google Scholar
PubMed
Close
,
C Simmons Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA

Search for other papers by C Simmons in
Google Scholar
PubMed
Close
,
O Rahal Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA
Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA

Search for other papers by O Rahal in
Google Scholar
PubMed
Close
, and
F A Simmen Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA
Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA

Search for other papers by F A Simmen in
Google Scholar
PubMed
Close

in the pathobiology of uterine endometrial and breast cancers. Figure 1 Cladogram of the human Sp and KLF transcription factors. The 110-aa domain containing the buttonhead box (BTD)/zinc finger motifs was used for the multiple alignment with ClustalW

Free access
Kyriaki S Alatzoglou Clinical and Academic Lead in Endocrinology, Developmental Endocrinology Research Group, Clinical and Molecular Genetics Unit, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK

Search for other papers by Kyriaki S Alatzoglou in
Google Scholar
PubMed
Close
,
Daniel Kelberman Clinical and Academic Lead in Endocrinology, Developmental Endocrinology Research Group, Clinical and Molecular Genetics Unit, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK

Search for other papers by Daniel Kelberman in
Google Scholar
PubMed
Close
, and
Mehul T Dattani Clinical and Academic Lead in Endocrinology, Developmental Endocrinology Research Group, Clinical and Molecular Genetics Unit, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK

Search for other papers by Mehul T Dattani in
Google Scholar
PubMed
Close

primordium and the correct morphogenesis of the gland require the sequential temporal and spatial expression of a cascade of signalling molecules and transcription factors that will eventually dictate organ commitment, cell proliferation, patterning and

Free access
John Le Lay Department of Molecular Physiology and Biophysics, Vanderbilt University, 2001 West End Ave Nashville, Tennessee 37235, USA

Search for other papers by John Le Lay in
Google Scholar
PubMed
Close
and
Roland Stein Department of Molecular Physiology and Biophysics, Vanderbilt University, 2001 West End Ave Nashville, Tennessee 37235, USA

Search for other papers by Roland Stein in
Google Scholar
PubMed
Close

Transcription factor occupancy of the insulin gene in vivo. Evidence for direct regulation by Nkx2.2. Journal of Biological Chemistry 278 751 –756. Clark AR , Wilson ME, Leibiger I, Scott V & Docherty K 1995 A silencer and an

Free access
Ying-Ying Tsai Department of Physiology, Medical College of Georgia at Augusta University (formerly Georgia Regents University), Augusta, Georgia, USA

Search for other papers by Ying-Ying Tsai in
Google Scholar
PubMed
Close
,
William E Rainey Departments of Molecular & Integrative Physiology and Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA

Search for other papers by William E Rainey in
Google Scholar
PubMed
Close
, and
Wendy B Bollag Department of Physiology, Medical College of Georgia at Augusta University (formerly Georgia Regents University), Augusta, Georgia, USA
Charlie Norwood VA Medical Center, One Freedom Way, Augusta, Georgia, USA

Search for other papers by Wendy B Bollag in
Google Scholar
PubMed
Close

absent steroid hormone production and enlarged adrenal glands. Transcription factors, such as cAMP response element-binding protein (CREB), steroidogenic factor 1 (SF-1) and adrenal hypoplasia critical region on chromosome X gene 1 (DAX-1 or NR0B1), may

Free access
R Wang
Search for other papers by R Wang in
Google Scholar
PubMed
Close
,
J Li
Search for other papers by J Li in
Google Scholar
PubMed
Close
,
N Yashpal
Search for other papers by N Yashpal in
Google Scholar
PubMed
Close
, and
N Gao
Search for other papers by N Gao in
Google Scholar
PubMed
Close

immunofluorescent staining was performed. There were two sets of co-expression pattern studies. First co-expression of nestin with transcription factors was examined. Co-staining of nestin with PDX-1 was observed at 15±4% in the monolayers after 2 months of culture

Free access
David J Mellis Musculoskeletal Research Programme, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen AB252ZD, UK

Search for other papers by David J Mellis in
Google Scholar
PubMed
Close
,
Cecile Itzstein Musculoskeletal Research Programme, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen AB252ZD, UK

Search for other papers by Cecile Itzstein in
Google Scholar
PubMed
Close
,
Miep H Helfrich Musculoskeletal Research Programme, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen AB252ZD, UK

Search for other papers by Miep H Helfrich in
Google Scholar
PubMed
Close
, and
Julie C Crockett Musculoskeletal Research Programme, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen AB252ZD, UK

Search for other papers by Julie C Crockett in
Google Scholar
PubMed
Close

signalling pathways leading to the activation of transcription factors, with the NFκB pathway being of particular importance. The control of osteoclast differentiation and function by signalling pathways is highlighted by conditions in which key components of

Free access