Search Results
Search for other papers by Laura Fozzatti in
Google Scholar
PubMed
Search for other papers by María L Vélez in
Google Scholar
PubMed
Search for other papers by Ariel M Lucero in
Google Scholar
PubMed
Search for other papers by Juan P Nicola in
Google Scholar
PubMed
Search for other papers by Iván D Mascanfroni in
Google Scholar
PubMed
Search for other papers by Daniela R Macció in
Google Scholar
PubMed
Search for other papers by Claudia G Pellizas in
Google Scholar
PubMed
Search for other papers by Germán A Roth in
Google Scholar
PubMed
Search for other papers by Ana M Masini-Repiso in
Google Scholar
PubMed
regulated by thyrotrophin (TSH) mainly by the modulation of thyroid-specific genes, such as NIS, TG and TPO ( Dunn & Dunn 2001 ). The existence of a basal tonic level of endogenous NO generation with a possible autocrine or paracrine role in the
Search for other papers by Elaine Cristina Lima de Souza in
Google Scholar
PubMed
Search for other papers by Álvaro Souto Padrón in
Google Scholar
PubMed
Search for other papers by William Miranda Oliveira Braga in
Google Scholar
PubMed
Search for other papers by Bruno Moulin de Andrade in
Google Scholar
PubMed
Search for other papers by Mário Vaisman in
Google Scholar
PubMed
Search for other papers by Luiz Eurico Nasciutti in
Google Scholar
PubMed
Search for other papers by Andrea Claudia Freitas Ferreira in
Google Scholar
PubMed
Search for other papers by Denise Pires de Carvalho in
Google Scholar
PubMed
physiology. The ability of the thyroid gland to accumulate radioiodine is also important for the diagnosis and treatment of thyroid disorders ( Mazaferri 2000 ). TSH is the major regulator of thyroid cell proliferation, differentiation, and function
Search for other papers by Nadia Schoenmakers in
Google Scholar
PubMed
Search for other papers by Kyriaki S Alatzoglou in
Google Scholar
PubMed
Search for other papers by V Krishna Chatterjee in
Google Scholar
PubMed
Search for other papers by Mehul T Dattani in
Google Scholar
PubMed
Introduction Central congenital hypothyroidism (CCH) is a rare disorder in which inadequate thyroid hormone biosynthesis occurs due to defective stimulation of a normal thyroid gland by thyroid stimulating hormone (TSH). The underlying molecular
Search for other papers by Eleonore Fröhlich in
Google Scholar
PubMed
Search for other papers by Anja Witke in
Google Scholar
PubMed
Search for other papers by Barbara Czarnocka in
Google Scholar
PubMed
Search for other papers by Richard Wahl in
Google Scholar
PubMed
(TSH)-induced uptake of iodide and the release of organified iodine in normal human thyrocytes ( Namba et al. 1993 ). High concentrations of retinol also exert dedifferentiating effects on normal thyrocytes ( Fröhlich et al. 2001 ). These effects
Search for other papers by K J Oliveira in
Google Scholar
PubMed
Search for other papers by G S M Paula in
Google Scholar
PubMed
Search for other papers by R H Costa-e-Sousa in
Google Scholar
PubMed
Search for other papers by L L Souza in
Google Scholar
PubMed
Search for other papers by D C Moraes in
Google Scholar
PubMed
Search for other papers by F H Curty in
Google Scholar
PubMed
Search for other papers by C C Pazos-Moura in
Google Scholar
PubMed
intracerebroventricular administration of NPY to normally fed rats resulted in reduction of circulating levels of thyroid hormones with inappropriately normal or low thyrotropin (TSH), and suppression of proTRH mRNA in the hypothalamic paraventricular nucleus (PVN
Search for other papers by Andrea C F Ferreira in
Google Scholar
PubMed
Search for other papers by Lívia P Lima in
Google Scholar
PubMed
Search for other papers by Renata L Araújo in
Google Scholar
PubMed
Search for other papers by Glaucia Müller in
Google Scholar
PubMed
Search for other papers by Renata P Rocha in
Google Scholar
PubMed
Search for other papers by Doris Rosenthal in
Google Scholar
PubMed
Search for other papers by Denise P Carvalho in
Google Scholar
PubMed
underlying the control of NIS expression, and the regulation of its activity in the plasma membrane. The ability of the thyroid gland to concentrate iodine has been known for several decades and many reports have demonstrated that thyrotrophin (TSH
Search for other papers by J Fahrenkrug in
Google Scholar
PubMed
Search for other papers by B Georg in
Google Scholar
PubMed
Search for other papers by J Hannibal in
Google Scholar
PubMed
Search for other papers by H L Jørgensen in
Google Scholar
PubMed
the cytoplasm, CRY and PER proteins translocate into the nucleus and form inhibitory complexes feeding negatively back on their own transcription. A daily rhythmicity of circulating thyroid-stimulating hormone (TSH) peaking at daytime in rats is well
Search for other papers by D C Ferguson in
Google Scholar
PubMed
Search for other papers by Z Caffall in
Google Scholar
PubMed
Search for other papers by M Hoenig in
Google Scholar
PubMed
et al. 1991 , Silva 1995 ). However, studies of thyroid function in obese people have produced inconsistent results. Obesity has resulted in either no changes in thyroid-stimulating hormone (TSH) or TH concentrations in the hands of some
Search for other papers by Thierry Métayé in
Google Scholar
PubMed
Search for other papers by Pierre Levillain in
Google Scholar
PubMed
Search for other papers by Jean-Louis Kraimps in
Google Scholar
PubMed
Search for other papers by Rémy Perdrisot in
Google Scholar
PubMed
) the β-adrenergic receptor kinases (GRK2 and GRK3), and 3) the GRK4, GRK5, and GRK6 subfamily ( Ribas et al . 2007 ). The thyrotropin (TSH) receptor belongs to the GPCR family and is a major determinant of thyroid function ( Vassart & Dumont 1992
Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, Shandong, China
Institute of Endocrinology and Metabolism, Shandong Academy of Clinical Medicine, Jinan, Shandong, China
Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Search for other papers by Sisi Luan in
Google Scholar
PubMed
Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, Shandong, China
Institute of Endocrinology and Metabolism, Shandong Academy of Clinical Medicine, Jinan, Shandong, China
Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Search for other papers by Wenkai Bi in
Google Scholar
PubMed
Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, Shandong, China
Institute of Endocrinology and Metabolism, Shandong Academy of Clinical Medicine, Jinan, Shandong, China
Search for other papers by Shulong Shi in
Google Scholar
PubMed
Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, Shandong, China
Institute of Endocrinology and Metabolism, Shandong Academy of Clinical Medicine, Jinan, Shandong, China
Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Search for other papers by Li Peng in
Google Scholar
PubMed
Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, Shandong, China
Institute of Endocrinology and Metabolism, Shandong Academy of Clinical Medicine, Jinan, Shandong, China
Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Search for other papers by Zhanbin Li in
Google Scholar
PubMed
Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, Shandong, China
Institute of Endocrinology and Metabolism, Shandong Academy of Clinical Medicine, Jinan, Shandong, China
Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Search for other papers by Jie Jiang in
Google Scholar
PubMed
Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, Shandong, China
Institute of Endocrinology and Metabolism, Shandong Academy of Clinical Medicine, Jinan, Shandong, China
Search for other papers by Ling Gao in
Google Scholar
PubMed
Search for other papers by Yifeng Du in
Google Scholar
PubMed
Department of Endocrinology, Shandong Provincial Hospital affiliated to Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China
Stem Cell Research Center, Shandong Provincial Hospital affiliated to First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China
Search for other papers by Xu Hou in
Google Scholar
PubMed
Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, Shandong, China
Institute of Endocrinology and Metabolism, Shandong Academy of Clinical Medicine, Jinan, Shandong, China
Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Department of Endocrinology, Shandong Provincial Hospital affiliated to Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China
Search for other papers by Zhao He in
Google Scholar
PubMed
Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, Shandong, China
Institute of Endocrinology and Metabolism, Shandong Academy of Clinical Medicine, Jinan, Shandong, China
Department of Endocrinology, Shandong Provincial Hospital affiliated to Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China
Search for other papers by Jiajun Zhao in
Google Scholar
PubMed
Introduction Thyroid hormones are produced and released by the thyroid gland, which regulate the metabolism of the body. The endocrine function of the thyroid gland is mediated by TSH, a glycoprotein hormone produced by the anterior pituitary