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Louis Potier
Louis Potier
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Ludovic Waeckel
Ludovic Waeckel
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Fréderic Fumeron
Fréderic Fumeron
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Sophie Bodin
Sophie Bodin
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Marinos Fysekidis
Marinos Fysekidis
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Catherine Chollet
Catherine Chollet
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Naima Bellili
Naima Bellili
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Fabrice Bonnet
Fabrice Bonnet
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Gaëlle Gusto
Gaëlle Gusto
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Gilberto Velho
Gilberto Velho
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Michel Marre
Michel Marre
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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François Alhenc-Gelas
François Alhenc-Gelas
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Ronan Roussel
Ronan Roussel
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Nadine Bouby
Nadine Bouby
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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the DESIR study group
the DESIR study group
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obesity-related disorders have provided encouraging but still limited results ( Satterfield et al . 2003 , Laatikainen et al . 2007 ). The pathogenesis of insulin resistance and diabetes in obesity is complex and still incompletely understood. Besides
Alex Rafacho
Alex Rafacho
Department of Physiological Sciences, Department of Clinical Science and Education, Institute of Bioengineering and the Biomedical Research Center in Diabetes and Associated Metabolic Disorders (CIBERDEM), Center of Biological Sciences, Federal University of Santa Catarina (UFSC), 88040-900, Florianópolis, SC, Brazil
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Henrik Ortsäter
Henrik Ortsäter
Department of Physiological Sciences, Department of Clinical Science and Education, Institute of Bioengineering and the Biomedical Research Center in Diabetes and Associated Metabolic Disorders (CIBERDEM), Center of Biological Sciences, Federal University of Santa Catarina (UFSC), 88040-900, Florianópolis, SC, Brazil
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Angel Nadal
Angel Nadal
Department of Physiological Sciences, Department of Clinical Science and Education, Institute of Bioengineering and the Biomedical Research Center in Diabetes and Associated Metabolic Disorders (CIBERDEM), Center of Biological Sciences, Federal University of Santa Catarina (UFSC), 88040-900, Florianópolis, SC, Brazil
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Ivan Quesada
Ivan Quesada
Department of Physiological Sciences, Department of Clinical Science and Education, Institute of Bioengineering and the Biomedical Research Center in Diabetes and Associated Metabolic Disorders (CIBERDEM), Center of Biological Sciences, Federal University of Santa Catarina (UFSC), 88040-900, Florianópolis, SC, Brazil
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effects, including peripheral insulin resistance (IR) and glucose intolerance as well as overt hyperglycaemia and diabetes. These side effects are observed particularly in susceptible individuals such as pregnant women, obese subjects, IR individuals or
Noèlia Téllez
Noèlia Téllez
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
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CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
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Eduard Montanya
Eduard Montanya
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
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CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
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Introduction β-cell mass reduction is a central event in the development of types 1 and 2 diabetes, and β-cell regeneration is a potentially curative treatment for the disease. Strategies aiming to regenerate β-cell mass include stimulation of
Lucy M Hinder
Lucy M Hinder
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Anuradha Vivekanandan-Giri
Anuradha Vivekanandan-Giri
Department of Neurology, Department of Internal Medicine, University of Michigan, AATBSRB, 109 Zina Pitcher Place, Ann Arbor, Michigan 48109-2200, USA
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Lisa L McLean
Lisa L McLean
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Subramaniam Pennathur
Subramaniam Pennathur
Department of Neurology, Department of Internal Medicine, University of Michigan, AATBSRB, 109 Zina Pitcher Place, Ann Arbor, Michigan 48109-2200, USA
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Eva L Feldman
Eva L Feldman
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Introduction According to statistics published by the Centers for Disease Control (2011) , ∼8% of the US population has diabetes mellitus, with 1.9 million new cases diagnosed in 2010. Although both type 1 diabetes and type 2 diabetes are
Xuefeng Yang
Xuefeng Yang
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Shuang Mei
Shuang Mei
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Haihua Gu
Haihua Gu
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Huailan Guo
Huailan Guo
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Longying Zha
Longying Zha
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Junwei Cai
Junwei Cai
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Xuefeng Li
Xuefeng Li
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Zhenqi Liu
Zhenqi Liu
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Wenhong Cao
Wenhong Cao
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Introduction Type 2 diabetes mellitus (T2DM) has become a major health and economic burden to industrialized societies. Its negative impact on the general health and economy is still rapidly increasing due to the continuing industrialization. It is
Kaitlyn A Colglazier
Kaitlyn A Colglazier
Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, Indiana, USA
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Noyonika Mukherjee
Noyonika Mukherjee
Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA
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Christopher J Contreras
Christopher J Contreras
Division of Endocrinology, Department of Medicine, Roudebush VA Medical Center and Indiana University School of Medicine, Indianapolis, Indiana, USA
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Andrew T Templin
Andrew T Templin
Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, Indiana, USA
Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA
Division of Endocrinology, Department of Medicine, Roudebush VA Medical Center and Indiana University School of Medicine, Indianapolis, Indiana, USA
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, Indiana, USA
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Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA
Division of Endocrinology, Department of Medicine, Roudebush VA Medical Center and Indiana University School of Medicine, Indianapolis, Indiana, USA
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, Indiana, USA
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the Templin Lab focuses on understanding the relationship between islet immune responses and β-cell dysfunction and death in the setting of both major forms of diabetes. Emphasis is placed on the concept that β-cell intrinsic properties are drivers of
Neil Tanday
Neil Tanday
SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, UK
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Peter R Flatt
Peter R Flatt
SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, UK
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Nigel Irwin
Nigel Irwin
SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, UK
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R Charlotte Moffett
R Charlotte Moffett
SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, UK
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Introduction The pathogenesis of diabetes is complex, involving many processes that ultimately results in pancreatic beta-cell dysfunction and/or development of peripheral insulin resistance ( Weir & Bonner-Weir 2004 ). The deficit of beta
Ziping Jiang
Ziping Jiang
Department of Hand and Foot Surgery, The First Hospital of Jilin University, Changchun, Jilin, China
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Junduo Wu
Junduo Wu
Department of Cardiology, The Second Hospital of Jilin University
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Fuzhe Ma
Fuzhe Ma
Department of Nephrology, The First Hospital of Jilin University, Changchun, Jilin, China
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Jun Jiang
Jun Jiang
Department of Neurosurgery, The Second Hospital of Shandong University, Jinan, Shandong, China
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Linlin Xu
Linlin Xu
Department of Neurology, The Second Hospital of Shandong University, Jinan, Shandong, China
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Lei Du
Lei Du
Department of Nutrition and Food Hygiene, School of Public Health, Shandong University, Jinan, Shandong, China
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Wenlin Huang
Wenlin Huang
School of Science and Technology, Georgia Gwinnett College, Lawrenceville, Georgia, USA
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Zhaohui Wang
Zhaohui Wang
Department of Acupuncture and Tuina, Changchun University of Chinese Medicine, Changchun, Jilin, China
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Ye Jia
Ye Jia
Department of Diabetes Complications and Metabolism, Diabetes Metabolism Research Institute, Beckman Research Institute of City of Hope, Duarte, California, USA
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Laijin Lu
Laijin Lu
Department of Hand and Foot Surgery, The First Hospital of Jilin University, Changchun, Jilin, China
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Hao Wu
Hao Wu
Department of Nutrition and Food Hygiene, School of Public Health, Shandong University, Jinan, Shandong, China
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oxygenase 1 ( Ho1 ) ( Ruiz et al . 2013 ), the protein products of which function as antioxidants that scavenge upon excessive diabetes mellitus (DM)-generated free radicals. In the cytoplasm, NRF2 is sequestered by kelch-like ECH-associated protein 1 (KEAP
Kok Lim Kua
Kok Lim Kua
Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
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Shanming Hu
Shanming Hu
Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
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Chunlin Wang
Chunlin Wang
Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
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Jianrong Yao
Jianrong Yao
Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
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Diana Dang
Diana Dang
Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
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Alexander B Sawatzke
Alexander B Sawatzke
Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
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Jeffrey L Segar
Jeffrey L Segar
Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
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Kai Wang
Kai Wang
Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa, USA
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Andrew W Norris
Andrew W Norris
Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa, USA
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Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa, USA
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Introduction Offspring born from pregnancy complicated by diabetes have a lifelong increased risk of insulin resistance. In humans, such offspring have a 4- to 8-fold higher risk, beyond genetic risk, to develop type 2 diabetes, metabolic
Christine A Beamish
Christine A Beamish
Department of Surgery, Houston Methodist Research Institute, Houston, Texas, USA
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Yoon K Lee
Yoon K Lee
Department of Surgery, Houston Methodist Research Institute, Houston, Texas, USA
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A Osama Gaber
A Osama Gaber
Department of Surgery, Houston Methodist Research Institute, Houston, Texas, USA
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Priyanka Chanana
Priyanka Chanana
Department of Surgery, Houston Methodist Research Institute, Houston, Texas, USA
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Edward A Graviss
Edward A Graviss
Department of Surgery, Houston Methodist Research Institute, Houston, Texas, USA
Department of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, Texas, USA
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Department of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, Texas, USA
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Malgorzata Kloc
Malgorzata Kloc
Department of Surgery, Houston Methodist Research Institute, Houston, Texas, USA
Department of Cell and Microbiology, Weill Cornell Medical College, New York, New York, USA
Department of Genetics, The University of Texas Anderson Cancer Center, Houston, Texas, USA
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Department of Cell and Microbiology, Weill Cornell Medical College, New York, New York, USA
Department of Genetics, The University of Texas Anderson Cancer Center, Houston, Texas, USA
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M Waleed Gaber
M Waleed Gaber
Department of Pediatrics, Hematology-Oncology Section, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA
Department of Molecular Physiology & Biophysics, Baylor College of Medicine, Houston, Texas, USA
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Department of Molecular Physiology & Biophysics, Baylor College of Medicine, Houston, Texas, USA
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Willa A Hsueh
Willa A Hsueh
Department of Internal Medicine, The Ohio State University Diabetes and Metabolism Research Center, Columbus, Ohio, USA
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Omaima M Sabek
Omaima M Sabek
Department of Surgery, Houston Methodist Research Institute, Houston, Texas, USA
Department of Cell and Microbiology, Weill Cornell Medical College, New York, New York, USA
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Department of Cell and Microbiology, Weill Cornell Medical College, New York, New York, USA
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liver disease ( Chitturi et al. 2002 ), and type 2 diabetes mellitus (T2D) ( Wilson et al. 2005 , Morrison et al. 2008 ). β-cell failure has been proposed to be a central feature of T2D pathogenesis and may include changes in oxidative or
