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Anne R O'Connell, Kenneth P McNatty, Peter R Hurst, Thomas E Spencer, Fuller W Bazer, Karen L Reader, Peter D Johnstone, George H Davis, and Jennifer L Juengel

failure of multiple ovulation (PFMO). In cases of PFMO, infertility of the male is excluded because at least one embryo is healthy. It is known that survival of an individual ovum is related to the number of ova ovulated, with ewes ovulating two ova that

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Antonia Hufnagel, Laura Dearden, Denise S Fernandez-Twinn, and Susan E Ozanne

placenta at term ( Nelson et al. 1978 ). The glycocalyx, a network of glycoproteins, is present on the maternal microvillous membrane and has been proposed to play a role in the regulation of transport across the syncytiotrophoblast ( Fabre-Gray et al

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Yan-Guang Wu, David H Barad, Vitaly A Kushnir, Emanuela Lazzaroni, Qi Wang, David F Albertini, and Norbert Gleicher

, however, related to the poor reproductive performance in women above age 43. Accordingly, we hypothesized that fast decreasing IVF pregnancy rates in older patients reflect poor ovarian environments, which adversely impacts oocyte/embryo quality and IVF

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Yusuke Kumai, Nicholas J Bernier, and Steve F Perry

expression and/or activities of all major transporters involved with Na + and acid transport in the various segments of the nephron, including Na + /H + exchanger 3 (NHE3; Geibel et al . 1990 , Cano et al . 1994 ), H + -ATPase ( Rothenberger et al

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Sara Della Torre, Gianpaolo Rando, Clara Meda, Paolo Ciana, Luisa Ottobrini, and Adriana Maggi

active in most reproductive and non-reproductive tissue cells ( Ciocca & Roig 1995 , Maggi et al. 2004 , Bookout et al. 2006 ). Their expression and transcriptional activity in the course of embryo development is less studied ( Brandenberger et al

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Mitra Arianmanesh, Rebecca H McIntosh, Richard G Lea, Paul A Fowler, and Kaïs H Al-Gubory

for uterine receptivity and are required for the implantation, survival and development of pre-implantation embryos, eventually leading to successful pregnancy outcomes ( Schlafke & Enders 1975 , Niswender et al . 2000 ). Many locally produced

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Sophie E Leney and Jeremy M Tavaré

-responsive glucose transporter isoform GLUT4 The effect of insulin on glucose transport into muscle and adipose first became apparent in the 1950s when several groups demonstrated that insulin was able to accelerate the rate of glucose uptake into these tissues

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M F Machado, V M Portela, C A Price, I B Costa, P Ripamonte, R L Amorim, and J Buratini Jr

epithelial cells ( Polnaszek et al . 2004 ), human placenta, and in mouse oocytes and embryos ( Zhong et al . 2006 ). The objective of the present work was to test the hypothesis that FGF17 is a candidate for paracrine signaling within the follicle

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Yanwen Jiang, Lu Chen, Robert N Taylor, Chunjin Li, and Xu Zhou

-privileged matrix for embryo implantation ( Gellersen & Brosens 2014 ) and prevents the malignant transformation of endometrial epithelium under unopposed estrogenic action ( Cheng et al . 2008 ). Though progesterone is critical for the initiation and maintenance

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Jacqueline M Wallace

short first breeding season, low ovulation rate, failure to be mated, fertilisation failure and high embryo loss ( Beck et al. 1996 , Kenyon et al. 2014 , Edwards et al. 2016 ). The approach developed at the Rowett Institute bypasses many of