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Lovisa Lundholm
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Milica Putnik
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Michio Otsuki Department of Biosciences and Nutrition at Novum, Department of Medicine, Division of Endocrinology, Karolinska Institutet, SE-141 57 Huddinge, Sweden

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Sandra Andersson
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Claes Ohlsson Department of Biosciences and Nutrition at Novum, Department of Medicine, Division of Endocrinology, Karolinska Institutet, SE-141 57 Huddinge, Sweden

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Jan-Åke Gustafsson
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Karin Dahlman-Wright
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from effects on food intake ( Heine et al . 2000 ). Studies of changes in adipose gene expression in mice in response to estrogen administration support a direct role of the adipose tissue in control of fat mass by demonstrating estrogen regulation of

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-07-0277
Volume/Issue:
Volume 196: Issue 3
Free access
Lorraine O’Driscoll National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus Sygehus THG, DK-Aarhus C, Denmark

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Patrick Gammell National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus Sygehus THG, DK-Aarhus C, Denmark

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Eadaoin McKiernan National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus Sygehus THG, DK-Aarhus C, Denmark

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Eoin Ryan National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus Sygehus THG, DK-Aarhus C, Denmark

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Per Bendix Jeppesen National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus Sygehus THG, DK-Aarhus C, Denmark

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Sweta Rani National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus Sygehus THG, DK-Aarhus C, Denmark

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Martin Clynes National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus Sygehus THG, DK-Aarhus C, Denmark

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have investigated changes in gene expression in β cells cultured in optimum glucose concentrations compared with cells grown in much lower glucose levels. Other studies have analysed selected clones of the heterogeneous β cell population. Previous

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06894
Volume/Issue:
Volume 191: Issue 3
Free access
E A Parker Developmental Endocrinology Branch, National Institutes of Health, National Institute of Child Health and Human Development, Building 10/CRC, Rm 1-3330, MSC 1103, 10 Center drive, Bethesda, Maryland 20892, USA
Pediatric Endocrinology Unit, Department of Woman and Child Health, Karolinska Institute, Karolinska University Hospital, SE-171 76 Stockholm, Sweden

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A Hegde Developmental Endocrinology Branch, National Institutes of Health, National Institute of Child Health and Human Development, Building 10/CRC, Rm 1-3330, MSC 1103, 10 Center drive, Bethesda, Maryland 20892, USA
Pediatric Endocrinology Unit, Department of Woman and Child Health, Karolinska Institute, Karolinska University Hospital, SE-171 76 Stockholm, Sweden

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M Buckley Developmental Endocrinology Branch, National Institutes of Health, National Institute of Child Health and Human Development, Building 10/CRC, Rm 1-3330, MSC 1103, 10 Center drive, Bethesda, Maryland 20892, USA
Pediatric Endocrinology Unit, Department of Woman and Child Health, Karolinska Institute, Karolinska University Hospital, SE-171 76 Stockholm, Sweden

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K M Barnes Developmental Endocrinology Branch, National Institutes of Health, National Institute of Child Health and Human Development, Building 10/CRC, Rm 1-3330, MSC 1103, 10 Center drive, Bethesda, Maryland 20892, USA
Pediatric Endocrinology Unit, Department of Woman and Child Health, Karolinska Institute, Karolinska University Hospital, SE-171 76 Stockholm, Sweden

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J Baron Developmental Endocrinology Branch, National Institutes of Health, National Institute of Child Health and Human Development, Building 10/CRC, Rm 1-3330, MSC 1103, 10 Center drive, Bethesda, Maryland 20892, USA
Pediatric Endocrinology Unit, Department of Woman and Child Health, Karolinska Institute, Karolinska University Hospital, SE-171 76 Stockholm, Sweden

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O Nilsson Developmental Endocrinology Branch, National Institutes of Health, National Institute of Child Health and Human Development, Building 10/CRC, Rm 1-3330, MSC 1103, 10 Center drive, Bethesda, Maryland 20892, USA
Pediatric Endocrinology Unit, Department of Woman and Child Health, Karolinska Institute, Karolinska University Hospital, SE-171 76 Stockholm, Sweden

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and sensitivity. Therefore, to complement existing data based on immunohistochemistry and in situ hybridization and to try to resolve the controversies concerning GH–IGF system gene expression in the growth plate, we chose to use real-time PCR, a

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-07-0012
Volume/Issue:
Volume 194: Issue 1
Free access
Dilip K Garikipati School of Molecular Biosciences and
Department of Animal Sciences, Washington State University, 124 ASLB, Pullman, Washington 99164-6351, USA
United States Department of Agriculture, National Center for Cool and Cold Water Aquaculture, Kearneysville, West Virginia 25430, USA

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Scott A Gahr School of Molecular Biosciences and
Department of Animal Sciences, Washington State University, 124 ASLB, Pullman, Washington 99164-6351, USA
United States Department of Agriculture, National Center for Cool and Cold Water Aquaculture, Kearneysville, West Virginia 25430, USA

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Buel D Rodgers School of Molecular Biosciences and
Department of Animal Sciences, Washington State University, 124 ASLB, Pullman, Washington 99164-6351, USA
United States Department of Agriculture, National Center for Cool and Cold Water Aquaculture, Kearneysville, West Virginia 25430, USA

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organization of different fish myostatin genes, as well as species-specific expression patterns will significantly interest comparative and agricultural biologists alike. This information will be particularly important in the identification and cloning of MSTN

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06866
Volume/Issue:
Volume 190: Issue 3
Free access
Akira Takeshita Endocrine Center, Toranomon Hospital and Okinaka Memorial Institute for Medical Research, 2-2-2 Toranomon, Minato, Tokyo 105-8470, Japan
Department of Anatomy and Cell Biology, St Marianna University School of Medicine, Kawasaki, Kanagawa 216-8511, Japan
Department of Integrative Physiology, Gunma University School of Medicine, Maebashi, Gunma 371-8511, Japan

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Keiji Inagaki Endocrine Center, Toranomon Hospital and Okinaka Memorial Institute for Medical Research, 2-2-2 Toranomon, Minato, Tokyo 105-8470, Japan
Department of Anatomy and Cell Biology, St Marianna University School of Medicine, Kawasaki, Kanagawa 216-8511, Japan
Department of Integrative Physiology, Gunma University School of Medicine, Maebashi, Gunma 371-8511, Japan

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Junko Igarashi-Migitaka Endocrine Center, Toranomon Hospital and Okinaka Memorial Institute for Medical Research, 2-2-2 Toranomon, Minato, Tokyo 105-8470, Japan
Department of Anatomy and Cell Biology, St Marianna University School of Medicine, Kawasaki, Kanagawa 216-8511, Japan
Department of Integrative Physiology, Gunma University School of Medicine, Maebashi, Gunma 371-8511, Japan

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Yasunori Ozawa Endocrine Center, Toranomon Hospital and Okinaka Memorial Institute for Medical Research, 2-2-2 Toranomon, Minato, Tokyo 105-8470, Japan
Department of Anatomy and Cell Biology, St Marianna University School of Medicine, Kawasaki, Kanagawa 216-8511, Japan
Department of Integrative Physiology, Gunma University School of Medicine, Maebashi, Gunma 371-8511, Japan

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Noriyuki Koibuchi Endocrine Center, Toranomon Hospital and Okinaka Memorial Institute for Medical Research, 2-2-2 Toranomon, Minato, Tokyo 105-8470, Japan
Department of Anatomy and Cell Biology, St Marianna University School of Medicine, Kawasaki, Kanagawa 216-8511, Japan
Department of Integrative Physiology, Gunma University School of Medicine, Maebashi, Gunma 371-8511, Japan

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et al. 1998 , Lehmann et al. 1998 , Goodwin et al. 1999 ). A recent study revealed that SXR also regulates MDR1 gene expression ( Geick et al. 2001 , Synold et al. 2001 ). Diethylhexyl phthalate (DEHP) is widely used as a

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06664
Volume/Issue:
Volume 190: Issue 3
Free access
H Nishimoto Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
Animal Biotechnology Center, Livestock Improvement Association of Japan Inc, Tokyo, Japan
Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan

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R Matsutani Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
Animal Biotechnology Center, Livestock Improvement Association of Japan Inc, Tokyo, Japan
Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan

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S Yamamoto Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
Animal Biotechnology Center, Livestock Improvement Association of Japan Inc, Tokyo, Japan
Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan

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T Takahashi Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
Animal Biotechnology Center, Livestock Improvement Association of Japan Inc, Tokyo, Japan
Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan

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K-G Hayashi Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
Animal Biotechnology Center, Livestock Improvement Association of Japan Inc, Tokyo, Japan
Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan

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A Miyamoto Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
Animal Biotechnology Center, Livestock Improvement Association of Japan Inc, Tokyo, Japan
Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan

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S Hamano Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
Animal Biotechnology Center, Livestock Improvement Association of Japan Inc, Tokyo, Japan
Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan

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M Tetsuka Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
Animal Biotechnology Center, Livestock Improvement Association of Japan Inc, Tokyo, Japan
Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan

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lower than that in POF and EAD. Gene expression of GLUT1, 3 and 4 in tissues The mRNA encoding GLUT1, 3 and 4 were detected in various tissues (Table 4 ). The gene expression pattern of these GLUT was consistent with

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06210
Volume/Issue:
Volume 188: Issue 1
Free access
Regina Nostramo
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Andrej Tillinger
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Juan M Saavedra Department of Biochemistry and Molecular Biology, Section of Pharmacology, Department of Pathology, Institute of Experimental Endocrinology, New York Medical College, Valhalla, New York 10595, USA

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Ashok Kumar Department of Biochemistry and Molecular Biology, Section of Pharmacology, Department of Pathology, Institute of Experimental Endocrinology, New York Medical College, Valhalla, New York 10595, USA

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Varunkumar Pandey Department of Biochemistry and Molecular Biology, Section of Pharmacology, Department of Pathology, Institute of Experimental Endocrinology, New York Medical College, Valhalla, New York 10595, USA

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Lidia Serova
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Richard Kvetnansky Department of Biochemistry and Molecular Biology, Section of Pharmacology, Department of Pathology, Institute of Experimental Endocrinology, New York Medical College, Valhalla, New York 10595, USA

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Esther L Sabban
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response to the stress of insulin-induced hypoglycemia ( Bumpus et al . 1980 ). Ang II also induces catecholamine biosynthesis by elevating gene expression of the catecholamine biosynthetic enzymes, tyrosine hydroxylase (TH), and phenylethanolamine N

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0181
Volume/Issue:
Volume 215: Issue 2
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Tusty-Jiuan Hsieh
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Pierre Fustier
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Chih-Chang Wei
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Shao-Ling Zhang
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Janos G Filep
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Shiow-Shiu Tang
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Julie R Ingelfinger
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I George Fantus
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Pavel Hamet
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John S D Chan
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induction of IRPTC hypertrophy ( Zhang et al. 2001 , 2002 c ). More recently, we demonstrated that the stimulatory effect of high concentrations of glucose on the expression of ANG gene and IRPTC hypertrophy is mediated, at least in part, via generation

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.05871
Volume/Issue:
Volume 183: Issue 3
Free access
Bettina A Ikenasio-Thorpe Liggins Institute and the National Research Centre for Growth and Development, University of Auckland, Auckland, New Zealand

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Bernhard H Breier Liggins Institute and the National Research Centre for Growth and Development, University of Auckland, Auckland, New Zealand

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Mark H Vickers Liggins Institute and the National Research Centre for Growth and Development, University of Auckland, Auckland, New Zealand

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Mhoyra Fraser Liggins Institute and the National Research Centre for Growth and Development, University of Auckland, Auckland, New Zealand

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status of the pregnant mother can alter the offspring’s neuroendocrine system. However, the long-term consequences of maternal undernutrition during pregnancy on neuroendocrine gene expression in adult offspring are currently unknown, particularly when a

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.07017
Volume/Issue:
Volume 193: Issue 1
Free access
K Hamano National Research Institute of Fisheries Science, Yokohama, Kanagawa 236-8648, Japan
National Research Institute of Fisheries and Environment of Inland Sea, Ohno, Hiroshima 739-0452, Japan

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M Awaji National Research Institute of Fisheries Science, Yokohama, Kanagawa 236-8648, Japan
National Research Institute of Fisheries and Environment of Inland Sea, Ohno, Hiroshima 739-0452, Japan

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H Usuki National Research Institute of Fisheries Science, Yokohama, Kanagawa 236-8648, Japan
National Research Institute of Fisheries and Environment of Inland Sea, Ohno, Hiroshima 739-0452, Japan

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spite of these studies, direct evidence for the presence of the insulin-related peptide in bivalves has not been obtained. Therefore, we have conducted cDNA cloning and expression analysis of the oyster insulin-related peptide (oIRP) gene in C. gigas

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06284
Volume/Issue:
Volume 187: Issue 1
Free access