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Introduction It has become increasingly clear that pituitary hormones that have traditionally been seen as regulators of single bodily processes, including endocrine functions, have additional roles in physiology. The global deletion of these
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tumours, such as pituitary adenomas ( Spady et al . 1999 ). Most of the effects of oestrogen are mediated through its two receptors: oestrogen receptor alpha (ERα) and beta (ERβ) ( Mitchner et al . 1998 ). ERα expression has been detected in both normal
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Introduction The pituitary gland is a central regulator of growth, metabolism, reproduction and homeostasis. It consists of three lobes: the anterior and the later-involuting intermediate lobe form the adenohypophysis, while the neurohypophysis
Centro de Microscopia Electrónica, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina
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Centro de Microscopia Electrónica, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina
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Centro de Microscopia Electrónica, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina
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Centro de Microscopia Electrónica, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina
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Introduction Pituitary neuroendocrine tumours (PitNETs) are frequent neoplasms and account for 15% of all intracranial tumours ( Hauser et al. 2019 ). They exhibit a wide range of clinical behaviours, from benign to aggressive, which are
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specific affinities for the CRF 2 receptor ( Hsu & Hsueh 2001 , Reyes et al. 2001 ). An immunohistochemical study has shown that Ucn 2-like immunoreactivity is present in the posterior pituitary and atria of mice ( Hsu & Hsueh 2001 ), while
Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan
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Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan
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Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan
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Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan
Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan
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Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan
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Introduction Pituitary folliculostellate (FS) cells are stellate and S100B protein-positive cells that surround neighboring endocrine cells by their long cytoplasmic processes, which are considered to act as a sustentacular cell in the pituitary
Medical Research Council, Human Reproductive Sciences Unit, Centre for Reproductive Biology, The University of Edinburgh Chancellor’s Building, 49 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SB, UK
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Medical Research Council, Human Reproductive Sciences Unit, Centre for Reproductive Biology, The University of Edinburgh Chancellor’s Building, 49 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SB, UK
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Medical Research Council, Human Reproductive Sciences Unit, Centre for Reproductive Biology, The University of Edinburgh Chancellor’s Building, 49 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SB, UK
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Medical Research Council, Human Reproductive Sciences Unit, Centre for Reproductive Biology, The University of Edinburgh Chancellor’s Building, 49 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SB, UK
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Medical Research Council, Human Reproductive Sciences Unit, Centre for Reproductive Biology, The University of Edinburgh Chancellor’s Building, 49 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SB, UK
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Medical Research Council, Human Reproductive Sciences Unit, Centre for Reproductive Biology, The University of Edinburgh Chancellor’s Building, 49 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SB, UK
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Medical Research Council, Human Reproductive Sciences Unit, Centre for Reproductive Biology, The University of Edinburgh Chancellor’s Building, 49 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SB, UK
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Introduction In females the gonadotropins FSH and LH produced by pituitary gonadotropes are required for terminal follicular growth and regulation of ovulation number ( McNeilly et al. 1992 ). The patterns of the synthesis and
Istituto San Raffaele, Neurosurgical Department, Milano, Italy
Ludwig-Maximilians University, Neurosurgical Department, Munich, Germany
Klinikum Villingen-Schwenningen, Neurosurgical Department, Villingen-Schwenningen, Germany
Laboratorio de Fisiología y Biología Molecular, Departamento Ciencias Biológicas, FCEN-Universidad de Buenos Aires and CONICET, Buenos Aires, Argentina
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Istituto San Raffaele, Neurosurgical Department, Milano, Italy
Ludwig-Maximilians University, Neurosurgical Department, Munich, Germany
Klinikum Villingen-Schwenningen, Neurosurgical Department, Villingen-Schwenningen, Germany
Laboratorio de Fisiología y Biología Molecular, Departamento Ciencias Biológicas, FCEN-Universidad de Buenos Aires and CONICET, Buenos Aires, Argentina
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Istituto San Raffaele, Neurosurgical Department, Milano, Italy
Ludwig-Maximilians University, Neurosurgical Department, Munich, Germany
Klinikum Villingen-Schwenningen, Neurosurgical Department, Villingen-Schwenningen, Germany
Laboratorio de Fisiología y Biología Molecular, Departamento Ciencias Biológicas, FCEN-Universidad de Buenos Aires and CONICET, Buenos Aires, Argentina
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Istituto San Raffaele, Neurosurgical Department, Milano, Italy
Ludwig-Maximilians University, Neurosurgical Department, Munich, Germany
Klinikum Villingen-Schwenningen, Neurosurgical Department, Villingen-Schwenningen, Germany
Laboratorio de Fisiología y Biología Molecular, Departamento Ciencias Biológicas, FCEN-Universidad de Buenos Aires and CONICET, Buenos Aires, Argentina
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Istituto San Raffaele, Neurosurgical Department, Milano, Italy
Ludwig-Maximilians University, Neurosurgical Department, Munich, Germany
Klinikum Villingen-Schwenningen, Neurosurgical Department, Villingen-Schwenningen, Germany
Laboratorio de Fisiología y Biología Molecular, Departamento Ciencias Biológicas, FCEN-Universidad de Buenos Aires and CONICET, Buenos Aires, Argentina
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Istituto San Raffaele, Neurosurgical Department, Milano, Italy
Ludwig-Maximilians University, Neurosurgical Department, Munich, Germany
Klinikum Villingen-Schwenningen, Neurosurgical Department, Villingen-Schwenningen, Germany
Laboratorio de Fisiología y Biología Molecular, Departamento Ciencias Biológicas, FCEN-Universidad de Buenos Aires and CONICET, Buenos Aires, Argentina
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Istituto San Raffaele, Neurosurgical Department, Milano, Italy
Ludwig-Maximilians University, Neurosurgical Department, Munich, Germany
Klinikum Villingen-Schwenningen, Neurosurgical Department, Villingen-Schwenningen, Germany
Laboratorio de Fisiología y Biología Molecular, Departamento Ciencias Biológicas, FCEN-Universidad de Buenos Aires and CONICET, Buenos Aires, Argentina
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Istituto San Raffaele, Neurosurgical Department, Milano, Italy
Ludwig-Maximilians University, Neurosurgical Department, Munich, Germany
Klinikum Villingen-Schwenningen, Neurosurgical Department, Villingen-Schwenningen, Germany
Laboratorio de Fisiología y Biología Molecular, Departamento Ciencias Biológicas, FCEN-Universidad de Buenos Aires and CONICET, Buenos Aires, Argentina
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Introduction Angiogenesis, the formation of new blood vessels from pre-existing ones, is known to be a fundamental process in the expansion of solid tumours ( Carmeliet 2003 , Ferrara 2004 ) and is also essential for pituitary
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Introduction Development of in vitro systems is crucial for understanding the mechanism of regulation of pituitary hormone gene expression at the molecular level in fish. Whole pituitary gland cultures ( Yada et al . 1991 , Elango et al . 2006
Université Paris-Sud, Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, France
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Université Paris-Sud, Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, France
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Université Paris-Sud, Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, France
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Université Paris-Sud, Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, France
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Université Paris-Sud, Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, France
Assistance Publique-Hôpitaux de Paris, Service d’Endocrinologie et des Maladies de la Reproduction, Hôpital Bicêtre, Le Kremlin Bicêtre, France
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Université Paris-Sud, Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, France
Assistance Publique-Hôpitaux de Paris, Service d’Endocrinologie et des Maladies de la Reproduction, Hôpital Bicêtre, Le Kremlin Bicêtre, France
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Introduction Since 2006, mutations in the AIP (aryl hydrocarbon receptor-interacting protein) gene have been known to predispose humans to pituitary adenomas ( Vierimaa et al. 2006 ). Heterozygous mutations are found in 20% of familial