Filter

Refine by date

—

Refine by collections

Refine by access

  • Print
  • Save

Search Results

You are looking at 41 - 50 of 714 items for :

  • Refine by access: All content x
Clear All
Katherine N Balantekin Department of Exercise and Nutrition Sciences, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York, USA
Center for Ingestive Behavior Research, University at Buffalo, Buffalo, New York, USA

Search for other papers by Katherine N Balantekin in
Google Scholar
PubMed Close
,
Martin J Kretz Department of Exercise and Nutrition Sciences, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York, USA

Search for other papers by Martin J Kretz in
Google Scholar
PubMed Close
, and
Elizabeth G Mietlicki-Baase Department of Exercise and Nutrition Sciences, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York, USA
Center for Ingestive Behavior Research, University at Buffalo, Buffalo, New York, USA

Search for other papers by Elizabeth G Mietlicki-Baase in
Google Scholar
PubMed Close

options that cause fewer side effects, to decrease the act of binge eating. The glucagon-like peptide 1 (GLP-1) system has become an area of intense research focus due to its ability to reduce food intake and body weight in humans and non-human animals

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-23-0405
Volume/Issue:
Volume 262: Issue 1
Restricted access
Shou-Si Lu
Search for other papers by Shou-Si Lu in
Google Scholar
PubMed Close
,
Yun-Li Yu
Search for other papers by Yun-Li Yu in
Google Scholar
PubMed Close
,
Hao-Jie Zhu Key Lab of Drug Metabolism and Pharmacokinetics, Department of Pharmaceutical and Biomedical Science, China Pharmaceutical University, Nanjing 210009, People's Republic of China

Search for other papers by Hao-Jie Zhu in
Google Scholar
PubMed Close
,
Xiao-Dong Liu
Search for other papers by Xiao-Dong Liu in
Google Scholar
PubMed Close
,
Li Liu
Search for other papers by Li Liu in
Google Scholar
PubMed Close
,
Yao-Wu Liu
Search for other papers by Yao-Wu Liu in
Google Scholar
PubMed Close
,
Ping Wang
Search for other papers by Ping Wang in
Google Scholar
PubMed Close
,
Lin Xie
Search for other papers by Lin Xie in
Google Scholar
PubMed Close
, and
Guang-Ji Wang
Search for other papers by Guang-Ji Wang in
Google Scholar
PubMed Close

play is an important role in the regulation of endocrine pancreatic secretion. The intestinal products of the proglucagon gene, glucagon-like peptide-1 (GLP-1), has been shown to contribute significantly to the overall insulin response to oral glucose

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0419
Volume/Issue:
Volume 200: Issue 2
Free access
Antonella Amato
Search for other papers by Antonella Amato in
Google Scholar
PubMed Close
,
Sara Baldassano
Search for other papers by Sara Baldassano in
Google Scholar
PubMed Close
,
Rosa Liotta Laboratorio di Fisiologia Generale, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT), Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), Università di Palermo, Viale delle Scienze, 90128 Palermo, Italy

Search for other papers by Rosa Liotta in
Google Scholar
PubMed Close
,
Rosa Serio
Search for other papers by Rosa Serio in
Google Scholar
PubMed Close
, and
Flavia Mulè
Search for other papers by Flavia Mulè in
Google Scholar
PubMed Close

Introduction Glucagon-like peptide 1 (GLP1), produced by intestinal enteroendocrine L-cells in response to the ingestion of nutrients ( Schirra et al . 1996 ), is highly insulinotropic and an inhibitor of gastrointestinal motility, effects that

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0525
Volume/Issue:
Volume 221: Issue 1
Free access
Sara Baldassano Laboratorio di Fisiologia Generale, Dipartimento di Scienze e Tecnologie Molecolari e Biomolecolari (STEMBIO), Università di Palermo, Viale delle Scienze, 90128 Palermo, Italy

Search for other papers by Sara Baldassano in
Google Scholar
PubMed Close
,
Anna Lisa Bellanca Laboratorio di Fisiologia Generale, Dipartimento di Scienze e Tecnologie Molecolari e Biomolecolari (STEMBIO), Università di Palermo, Viale delle Scienze, 90128 Palermo, Italy

Search for other papers by Anna Lisa Bellanca in
Google Scholar
PubMed Close
,
Rosa Serio Laboratorio di Fisiologia Generale, Dipartimento di Scienze e Tecnologie Molecolari e Biomolecolari (STEMBIO), Università di Palermo, Viale delle Scienze, 90128 Palermo, Italy

Search for other papers by Rosa Serio in
Google Scholar
PubMed Close
, and
Flavia Mulè Laboratorio di Fisiologia Generale, Dipartimento di Scienze e Tecnologie Molecolari e Biomolecolari (STEMBIO), Università di Palermo, Viale delle Scienze, 90128 Palermo, Italy

Search for other papers by Flavia Mulè in
Google Scholar
PubMed Close

Introduction Glucagon-like peptide 2 (GLP2) is a 33-amino acid peptide, produced by the processing of the proglucagon gene within the mucosal L-cells of the intestine and specific neurons located in the brainstem. The actions of GLP2 are transduced

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0092
Volume/Issue:
Volume 213: Issue 3
Free access
Sara Baldassano Laboratorio di Fisiologia generale, Dipartimento di Scienze e Tecnologie Molecolari e Biomolecolari (STEMBIO) and, Dipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche, Università di Palermo, 90128 Palermo, Italy

Search for other papers by Sara Baldassano in
Google Scholar
PubMed Close
,
Antonella Amato Laboratorio di Fisiologia generale, Dipartimento di Scienze e Tecnologie Molecolari e Biomolecolari (STEMBIO) and, Dipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche, Università di Palermo, 90128 Palermo, Italy

Search for other papers by Antonella Amato in
Google Scholar
PubMed Close
,
Francesco Cappello Laboratorio di Fisiologia generale, Dipartimento di Scienze e Tecnologie Molecolari e Biomolecolari (STEMBIO) and, Dipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche, Università di Palermo, 90128 Palermo, Italy

Search for other papers by Francesco Cappello in
Google Scholar
PubMed Close
,
Francesca Rappa Laboratorio di Fisiologia generale, Dipartimento di Scienze e Tecnologie Molecolari e Biomolecolari (STEMBIO) and, Dipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche, Università di Palermo, 90128 Palermo, Italy

Search for other papers by Francesca Rappa in
Google Scholar
PubMed Close
, and
Flavia Mulè Laboratorio di Fisiologia generale, Dipartimento di Scienze e Tecnologie Molecolari e Biomolecolari (STEMBIO) and, Dipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche, Università di Palermo, 90128 Palermo, Italy

Search for other papers by Flavia Mulè in
Google Scholar
PubMed Close

, including the proglucagon-derived peptides, glucagon-like peptide-1 (GLP1), and GLP2, and there is evidence for a link among GLP2, intestinal growth, and increased energy intake ( Xiao et al . 1999 , Shin et al . 2005 , Nelson et al . 2008 ). GLP2 is a

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0500
Volume/Issue:
Volume 217: Issue 1
Free access
Guillaume Mabilleau GEROM Groupe Etudes Remodelage Osseux et biomatériaux, IRIS-IBS Institut de Biologie en Santé, CHU d’Angers, Université d’Angers, Angers, France

Search for other papers by Guillaume Mabilleau in
Google Scholar
PubMed Close
,
Marie Pereira Centre for Complement and Inflammation Research (CCIR), Department of Medicine, Imperial College London, London, UK

Search for other papers by Marie Pereira in
Google Scholar
PubMed Close
, and
Chantal Chenu Department of Comparative Biomedical Sciences, Royal Veterinary College, London, UK

Search for other papers by Chantal Chenu in
Google Scholar
PubMed Close

needed, to reach an HbA 1C level of 7% or less. Among the most prescribed drugs, the glucagon-like peptide-1 receptor agonists (GLP-1RAs) have recently attracted attention as Glp-1r -knockout animals, and GLP-1-supplemented animals exhibited

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-17-0278
Volume/Issue:
Volume 236: Issue 1
Free access
Jennifer A Crookshank Chronic Disease Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada

Search for other papers by Jennifer A Crookshank in
Google Scholar
PubMed Close
,
Daniel Serrano Chronic Disease Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada

Search for other papers by Daniel Serrano in
Google Scholar
PubMed Close
,
Gen-Sheng Wang Chronic Disease Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada

Search for other papers by Gen-Sheng Wang in
Google Scholar
PubMed Close
,
Christopher Patrick Chronic Disease Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada

Search for other papers by Christopher Patrick in
Google Scholar
PubMed Close
,
Baylie S Morgan Chronic Disease Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
Department of Biomedical Sciences, University of Ottawa, Ottawa, Ontario, Canada

Search for other papers by Baylie S Morgan in
Google Scholar
PubMed Close
,
Marie-France Paré Chronic Disease Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada

Search for other papers by Marie-France Paré in
Google Scholar
PubMed Close
, and
Fraser W Scott Chronic Disease Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada
Department of Medicine, The Ottawa Hospital, Ottawa, Ontario, Canada

Search for other papers by Fraser W Scott in
Google Scholar
PubMed Close

proteins were used: insulin (Agilent Technologies Canada Inc., Mississauga, Canada), proinsulin (Bio-Techne, Minneapolis, USA), glucagon (MilliporeSigma), BIP (Abcam Inc.). ImageJ (National Institute of Health) was used to quantify the insulin + and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0328
Volume/Issue:
Volume 239: Issue 2
Free access
Guillaume Mabilleau Groupe d'Etudes sur le Remodelage Osseux et les bioMatériaux (GEROM) – LHEA, Service Commun d'Imageries
et d'Analyses Microscopiques (SCIAM), School of Biomedical Sciences
Groupe d'Etudes sur le Remodelage Osseux et les bioMatériaux (GEROM) – LHEA, Service Commun d'Imageries
et d'Analyses Microscopiques (SCIAM), School of Biomedical Sciences

Search for other papers by Guillaume Mabilleau in
Google Scholar
PubMed Close
,
Aleksandra Mieczkowska Groupe d'Etudes sur le Remodelage Osseux et les bioMatériaux (GEROM) – LHEA, Service Commun d'Imageries
et d'Analyses Microscopiques (SCIAM), School of Biomedical Sciences

Search for other papers by Aleksandra Mieczkowska in
Google Scholar
PubMed Close
,
Nigel Irwin Groupe d'Etudes sur le Remodelage Osseux et les bioMatériaux (GEROM) – LHEA, Service Commun d'Imageries
et d'Analyses Microscopiques (SCIAM), School of Biomedical Sciences

Search for other papers by Nigel Irwin in
Google Scholar
PubMed Close
,
Peter R Flatt Groupe d'Etudes sur le Remodelage Osseux et les bioMatériaux (GEROM) – LHEA, Service Commun d'Imageries
et d'Analyses Microscopiques (SCIAM), School of Biomedical Sciences

Search for other papers by Peter R Flatt in
Google Scholar
PubMed Close
, and
Daniel Chappard Groupe d'Etudes sur le Remodelage Osseux et les bioMatériaux (GEROM) – LHEA, Service Commun d'Imageries
et d'Analyses Microscopiques (SCIAM), School of Biomedical Sciences
Groupe d'Etudes sur le Remodelage Osseux et les bioMatériaux (GEROM) – LHEA, Service Commun d'Imageries
et d'Analyses Microscopiques (SCIAM), School of Biomedical Sciences

Search for other papers by Daniel Chappard in
Google Scholar
PubMed Close

al . 2010 ). Glucagon-like peptide-1 (GLP1) is a gut hormone synthesized and secreted into the blood stream by intestinal endocrine L cells in response to a variety of stimuli ( Wu et al . 2010 ). Biologically active GLP1 is secreted as a 7–37 or 7

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0146
Volume/Issue:
Volume 219: Issue 1
Free access
Jun-ichi Eiki Tsukuba Research Institute, Division of Integrative Physiology, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan
Tsukuba Research Institute, Division of Integrative Physiology, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan

Search for other papers by Jun-ichi Eiki in
Google Scholar
PubMed Close
,
Kaori Saeki Tsukuba Research Institute, Division of Integrative Physiology, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan

Search for other papers by Kaori Saeki in
Google Scholar
PubMed Close
,
Norihiro Nagano Tsukuba Research Institute, Division of Integrative Physiology, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan

Search for other papers by Norihiro Nagano in
Google Scholar
PubMed Close
,
Tomoharu Iino Tsukuba Research Institute, Division of Integrative Physiology, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan

Search for other papers by Tomoharu Iino in
Google Scholar
PubMed Close
,
Mari Yonemoto Tsukuba Research Institute, Division of Integrative Physiology, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan

Search for other papers by Mari Yonemoto in
Google Scholar
PubMed Close
,
Yoko Takayenoki-Iino Tsukuba Research Institute, Division of Integrative Physiology, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan

Search for other papers by Yoko Takayenoki-Iino in
Google Scholar
PubMed Close
,
Satoru Ito Tsukuba Research Institute, Division of Integrative Physiology, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan

Search for other papers by Satoru Ito in
Google Scholar
PubMed Close
,
Teruyuki Nishimura Tsukuba Research Institute, Division of Integrative Physiology, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan

Search for other papers by Teruyuki Nishimura in
Google Scholar
PubMed Close
,
Yoshiyuki Sato Tsukuba Research Institute, Division of Integrative Physiology, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan

Search for other papers by Yoshiyuki Sato in
Google Scholar
PubMed Close
,
Makoto Bamba Tsukuba Research Institute, Division of Integrative Physiology, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan

Search for other papers by Makoto Bamba in
Google Scholar
PubMed Close
,
Hitomi Watanabe Tsukuba Research Institute, Division of Integrative Physiology, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan

Search for other papers by Hitomi Watanabe in
Google Scholar
PubMed Close
,
Kaori Sasaki Tsukuba Research Institute, Division of Integrative Physiology, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan

Search for other papers by Kaori Sasaki in
Google Scholar
PubMed Close
,
Sumika Ohyama Tsukuba Research Institute, Division of Integrative Physiology, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan

Search for other papers by Sumika Ohyama in
Google Scholar
PubMed Close
,
Akio Kanatani Tsukuba Research Institute, Division of Integrative Physiology, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan

Search for other papers by Akio Kanatani in
Google Scholar
PubMed Close
,
Toshio Nagase Tsukuba Research Institute, Division of Integrative Physiology, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan

Search for other papers by Toshio Nagase in
Google Scholar
PubMed Close
, and
Toshihiko Yada Tsukuba Research Institute, Division of Integrative Physiology, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan

Search for other papers by Toshihiko Yada in
Google Scholar
PubMed Close

Introduction Glucagon-like peptide-1 (GLP-1) is a hormone secreted from enteroendocrine L-cells, and is well recognized as an incretin that induces insulin secretion in a glucose-dependent manner ( Drucker 2006 ). The functions of GLP-1 have been

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0528
Volume/Issue:
Volume 201: Issue 3
Free access
Leila Arbabi Neuroscience Program, Monash Biomedicine Discovery Institute and Department of Physiology, Monash University, Melbourne, Victoria, Australia

Search for other papers by Leila Arbabi in
Google Scholar
PubMed Close
,
Qun Li Neuroscience Program, Monash Biomedicine Discovery Institute and Department of Physiology, Monash University, Melbourne, Victoria, Australia

Search for other papers by Qun Li in
Google Scholar
PubMed Close
,
Belinda A Henry Metabolism, Diabetes and Obesity Program, Monash Biomedicine Discovery Institute and Department of Physiology, Monash University, Melbourne, Victoria, Australia

Search for other papers by Belinda A Henry in
Google Scholar
PubMed Close
, and
Iain J Clarke Neuroscience Program, Monash Biomedicine Discovery Institute and Department of Physiology, Monash University, Melbourne, Victoria, Australia

Search for other papers by Iain J Clarke in
Google Scholar
PubMed Close

on GnRH secretion. Amongst other hormones, that regulate GnRH secretion, glucagon-like peptide-1 (GLP-1) from the gut and/or the brain has been shown to stimulate GnRH secretion, although the pathway for such an effect has not been elucidated. This

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-20-0335
Volume/Issue:
Volume 248: Issue 3
Restricted access