Search Results
Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada
Search for other papers by Erica Yeo in
Google Scholar
PubMed
Department of Medicine, University of Toronto, Toronto, ON, Canada
Search for other papers by Patricia L Brubaker in
Google Scholar
PubMed
Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada
Department of Obstetrics, Gynecology and Pediatrics, McMaster University, Hamilton, ON, Canada
Search for other papers by Deborah M Sloboda in
Google Scholar
PubMed
Introduction To accommodate the dynamic energy demands of pregnancy, while still maintaining metabolic homeostasis, significant alterations to maternal metabolism are required ( Fig. 1 ). Impaired or inappropriate maternal adaptations can
Search for other papers by Sergio Caja in
Google Scholar
PubMed
Search for other papers by Izaskun Martínez in
Google Scholar
PubMed
Search for other papers by María Abelenda in
Google Scholar
PubMed
Search for other papers by Marisa Puerta in
Google Scholar
PubMed
et al. 2004 ). During pregnancy, maternal and foetal growth is enabled by a substantial increase in food intake and substrate re-partitioning ( Abelenda & Puerta 1987 , Herrera et al. 2000 ). To this end, maternal insulin sensitivity
Department of Cancer Biology, Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA
Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA
Search for other papers by Yan Cao in
Google Scholar
PubMed
Search for other papers by Zijie Feng in
Google Scholar
PubMed
Search for other papers by Xin He in
Google Scholar
PubMed
Search for other papers by Xuyao Zhang in
Google Scholar
PubMed
Search for other papers by Bowen Xing in
Google Scholar
PubMed
Search for other papers by Yuan Wu in
Google Scholar
PubMed
Search for other papers by Taylor Hojnacki in
Google Scholar
PubMed
Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA
Search for other papers by Bryson W Katona in
Google Scholar
PubMed
Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA
Search for other papers by Jian Ma in
Google Scholar
PubMed
Department of Endocrinology, Southern University of Science and Technology Hospital, Shenzhen, China
Search for other papers by Xiaorong Zhan in
Google Scholar
PubMed
Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA
Search for other papers by Xianxin Hua in
Google Scholar
PubMed
Introduction Gestational diabetes mellitus (GDM), which is increasing in incidence, occurs during pregnancy with impaired glucose tolerance. GDM has a deleterious impact on the life of the mother and fetus both during and after pregnancy. GDM
Search for other papers by Dawid Szczepankiewicz in
Google Scholar
PubMed
Search for other papers by Ewa Pruszynska-Oszmalek in
Google Scholar
PubMed
Search for other papers by Przemyslaw Kaczmarek in
Google Scholar
PubMed
Search for other papers by Marek Skrzypski in
Google Scholar
PubMed
Search for other papers by Karolina Andralojc in
Google Scholar
PubMed
Search for other papers by Tatiana Wojciechowicz in
Google Scholar
PubMed
Search for other papers by Maciej Sassek in
Google Scholar
PubMed
Search for other papers by Krzysztof W Nowak in
Google Scholar
PubMed
pregnancy. Moreover, we present here that AGRP is also expressed in placenta during late pregnancy, which not only may influence energy homeostasis in the mother, but also may affect fetus development. Material and Methods Animals In this experiment, female
Buck Institute for Research on Aging, Novato, California, USA
Search for other papers by Michael C Velarde in
Google Scholar
PubMed
Department of Clinical Medicine and Obstetrics and Gynecology, Aarhus University, Aarhus, Denmark
Search for other papers by Ramkumar Menon in
Google Scholar
PubMed
, senescent cells are associated with pregnancy complications, such as preterm births. However, cellular senescence is also implicated in maintaining proper homeostasis during pregnancy, human parturition ( Behnia et al. 2015 ) and fetal development ( Muñoz
Search for other papers by B T Layden in
Google Scholar
PubMed
Search for other papers by V Durai in
Google Scholar
PubMed
Search for other papers by M V Newman in
Google Scholar
PubMed
Search for other papers by A M Marinelarena in
Google Scholar
PubMed
Search for other papers by C W Ahn in
Google Scholar
PubMed
Search for other papers by G Feng in
Google Scholar
PubMed
Search for other papers by S Lin in
Google Scholar
PubMed
Search for other papers by X Zhang in
Google Scholar
PubMed
Search for other papers by D B Kaufman in
Google Scholar
PubMed
Search for other papers by N Jafari in
Google Scholar
PubMed
Search for other papers by G L Sørensen in
Google Scholar
PubMed
Search for other papers by W L Lowe Jr in
Google Scholar
PubMed
resistant states of pregnancy and obesity ( Butler et al . 2007 ). Studying states in which insulin needs change can provide insight into pathways mediating β cell adaptations. In mice, β cell mass increases about twofold during pregnancy, with a maximum
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China
Search for other papers by Yan Su in
Google Scholar
PubMed
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China
Search for other papers by Sujuan Guo in
Google Scholar
PubMed
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China
Search for other papers by Chunyan Liu in
Google Scholar
PubMed
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China
Search for other papers by Na Li in
Google Scholar
PubMed
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China
Search for other papers by Shuang Zhang in
Google Scholar
PubMed
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China
Search for other papers by Yubin Ding in
Google Scholar
PubMed
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China
Search for other papers by Xuemei Chen in
Google Scholar
PubMed
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China
Search for other papers by Junlin He in
Google Scholar
PubMed
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China
Search for other papers by Xueqing Liu in
Google Scholar
PubMed
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China
Search for other papers by Yingxiong Wang in
Google Scholar
PubMed
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China
Search for other papers by Rufei Gao in
Google Scholar
PubMed
of pregnancy, embryo implantation and endometrial decidualization are considered as two of the most crucial steps which have a determinant impact on successful pregnancy ( Patterson et al . 2017 ). After embryo implantation, stromal cells around the
Search for other papers by Jiju Wang in
Google Scholar
PubMed
Search for other papers by Yunhui Tang in
Google Scholar
PubMed
Search for other papers by Songcun Wang in
Google Scholar
PubMed
Search for other papers by Liyuan Cui in
Google Scholar
PubMed
Search for other papers by Dajin Li in
Google Scholar
PubMed
Search for other papers by Meirong Du in
Google Scholar
PubMed
). Physiological or psychological stressors that induce the sympathetic nervous system’s ‘fight-or-flight’ response can rapidly increase the norepinephrine (NE) level ( Tank & Lee Wong 2015 ). However, the effect of NE on reproductive toxicity in early pregnancy
Department of Pharmaceutical Sciences, University of Salerno, ‘Federico II’, Naples, Italy
Department of Pathology and Animal Health, University of Naples ‘Federico II’, Naples, Italy
Search for other papers by Giuseppina Mattace Raso in
Google Scholar
PubMed
Department of Pharmaceutical Sciences, University of Salerno, ‘Federico II’, Naples, Italy
Department of Pathology and Animal Health, University of Naples ‘Federico II’, Naples, Italy
Search for other papers by Giuseppe Bianco in
Google Scholar
PubMed
Department of Pharmaceutical Sciences, University of Salerno, ‘Federico II’, Naples, Italy
Department of Pathology and Animal Health, University of Naples ‘Federico II’, Naples, Italy
Search for other papers by Anna Iacono in
Google Scholar
PubMed
Department of Pharmaceutical Sciences, University of Salerno, ‘Federico II’, Naples, Italy
Department of Pathology and Animal Health, University of Naples ‘Federico II’, Naples, Italy
Search for other papers by Emanuela Esposito in
Google Scholar
PubMed
Department of Pharmaceutical Sciences, University of Salerno, ‘Federico II’, Naples, Italy
Department of Pathology and Animal Health, University of Naples ‘Federico II’, Naples, Italy
Search for other papers by Giuseppina Autore in
Google Scholar
PubMed
Department of Pharmaceutical Sciences, University of Salerno, ‘Federico II’, Naples, Italy
Department of Pathology and Animal Health, University of Naples ‘Federico II’, Naples, Italy
Search for other papers by Maria Carmela Ferrante in
Google Scholar
PubMed
Department of Pharmaceutical Sciences, University of Salerno, ‘Federico II’, Naples, Italy
Department of Pathology and Animal Health, University of Naples ‘Federico II’, Naples, Italy
Search for other papers by Antonio Calignano in
Google Scholar
PubMed
Department of Pharmaceutical Sciences, University of Salerno, ‘Federico II’, Naples, Italy
Department of Pathology and Animal Health, University of Naples ‘Federico II’, Naples, Italy
Search for other papers by Rosaria Meli in
Google Scholar
PubMed
Introduction During pregnancy, several neuroendocrine changes and energy metabolism alterations occur. In this hypermetabolic state, a great increase in maternal body fat and weight and a positive energy balance are well recognized
Anatomy and Structural Biology, Otago School of Medical Sciences, University of Otago, PO Box 56, Dunedin 9054, New Zealand
Search for other papers by Tracy Josephs in
Google Scholar
PubMed
Anatomy and Structural Biology, Otago School of Medical Sciences, University of Otago, PO Box 56, Dunedin 9054, New Zealand
Search for other papers by Hayley Waugh in
Google Scholar
PubMed
Anatomy and Structural Biology, Otago School of Medical Sciences, University of Otago, PO Box 56, Dunedin 9054, New Zealand
Search for other papers by Ilona Kokay in
Google Scholar
PubMed
Anatomy and Structural Biology, Otago School of Medical Sciences, University of Otago, PO Box 56, Dunedin 9054, New Zealand
Search for other papers by David Grattan in
Google Scholar
PubMed
Anatomy and Structural Biology, Otago School of Medical Sciences, University of Otago, PO Box 56, Dunedin 9054, New Zealand
Search for other papers by Mary Thompson in
Google Scholar
PubMed
Introduction Pregnancy and lactation are physiological situations where major changes in energy homeostasis occur to meet the nutrient demands of fetal growth and milk production. The energy needs are met by increased food intake