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Andre Sarmento-Cabral Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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Mercedes del Rio-Moreno Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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Mari C Vazquez-Borrego Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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Mariyah Mahmood Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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Elena Gutierrez-Casado Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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Natalie Pelke Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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Grace Guzman Department of Pathology, University of Illinois at Chicago, College of Medicine, Chicago, Illinois, USA

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Papasani V Subbaiah Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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Jose Cordoba-Chacon Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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Shoshana Yakar Department of Molecular Pathobiology, New York University College of Dentistry, New York, New York, USA

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Rhonda D Kineman Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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. 2009 , Nordstrom et al. 2013 , List et al. 2014 , Liu et al. 2016 , Corbit et al. 2018 ). These changes in systemic metabolic function are thought to shift the flux of glucose and non-esterified fatty acids (NEFA) to the liver, thus

Article Type:
Research Article
Collections:
Top-cited articles of 2023
DOI:
https://doi.org/10.1530/JOE-20-0326
Volume/Issue:
Volume 248: Issue 1
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Daiana Fornes Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Laboratory of Reproduction and Metabolism, CEFYBO, Buenos Aires, Argentina

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Florencia Heinecke Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Laboratory of Programming of Metabolic Anomalies, CEFYBO, Buenos Aires, Argentina

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Cintia Romina Gatti Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Laboratory of Reproduction and Metabolism, CEFYBO, Buenos Aires, Argentina

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Sabrina Lorena Roberti Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Laboratory of Reproduction and Metabolism, CEFYBO, Buenos Aires, Argentina

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Verónica White Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Laboratory of Programming of Metabolic Anomalies, CEFYBO, Buenos Aires, Argentina

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Alicia Jawerbaum Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Laboratory of Reproduction and Metabolism, CEFYBO, Buenos Aires, Argentina

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Evangelina Capobianco Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Laboratory of Reproduction and Metabolism, CEFYBO, Buenos Aires, Argentina

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multiple factors that influence proper placental transport of nutrients include placental morphology and blood flow and abundance of transporters in the trophoblast ( Larqué et al. 2014 , Segura et al. 2017 ). Fatty acids (FAs) are lipid nutrients that

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-21-0301
Volume/Issue:
Volume 254: Issue 1
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Jenny D Y Chow Prince Henry's Institute, Anatomy and Cell Biology, Biochemistry and Molecular Biology, Bayer Pharma AG, Florey Neuroscience Institutes, Clayton, Victoria 3168, Australia Departments of
Prince Henry's Institute, Anatomy and Cell Biology, Biochemistry and Molecular Biology, Bayer Pharma AG, Florey Neuroscience Institutes, Clayton, Victoria 3168, Australia Departments of

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Margaret E E Jones Prince Henry's Institute, Anatomy and Cell Biology, Biochemistry and Molecular Biology, Bayer Pharma AG, Florey Neuroscience Institutes, Clayton, Victoria 3168, Australia Departments of
Prince Henry's Institute, Anatomy and Cell Biology, Biochemistry and Molecular Biology, Bayer Pharma AG, Florey Neuroscience Institutes, Clayton, Victoria 3168, Australia Departments of

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Katja Prelle Prince Henry's Institute, Anatomy and Cell Biology, Biochemistry and Molecular Biology, Bayer Pharma AG, Florey Neuroscience Institutes, Clayton, Victoria 3168, Australia Departments of

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Evan R Simpson Prince Henry's Institute, Anatomy and Cell Biology, Biochemistry and Molecular Biology, Bayer Pharma AG, Florey Neuroscience Institutes, Clayton, Victoria 3168, Australia Departments of
Prince Henry's Institute, Anatomy and Cell Biology, Biochemistry and Molecular Biology, Bayer Pharma AG, Florey Neuroscience Institutes, Clayton, Victoria 3168, Australia Departments of

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Wah Chin Boon Prince Henry's Institute, Anatomy and Cell Biology, Biochemistry and Molecular Biology, Bayer Pharma AG, Florey Neuroscience Institutes, Clayton, Victoria 3168, Australia Departments of
Prince Henry's Institute, Anatomy and Cell Biology, Biochemistry and Molecular Biology, Bayer Pharma AG, Florey Neuroscience Institutes, Clayton, Victoria 3168, Australia Departments of
Prince Henry's Institute, Anatomy and Cell Biology, Biochemistry and Molecular Biology, Bayer Pharma AG, Florey Neuroscience Institutes, Clayton, Victoria 3168, Australia Departments of

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examined the expression of Cpt1, a rate-limiting step in fatty acid β-oxidation, and found no change in its transcript level. This is in accordance with our previous report that there were neither changes in the expression of enzymes involved in the fatty

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-10-0462
Volume/Issue:
Volume 210: Issue 3
Free access
Jung-Yoon Heo Department of Physiology, College of Medicine, Yeungnam University, Daegu, Korea
Smart-Aging Convergence Research Center, College of Medicine, Yeungnam University, Daegu, Korea

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Ji-Eun Kim Department of Physiology, College of Medicine, Yeungnam University, Daegu, Korea
Smart-Aging Convergence Research Center, College of Medicine, Yeungnam University, Daegu, Korea

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Yongwook Dan Weinberg College, Northwestern University, Evanston, Illinois, USA

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Yong-Woon Kim Department of Physiology, College of Medicine, Yeungnam University, Daegu, Korea

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Jong-Yeon Kim Department of Physiology, College of Medicine, Yeungnam University, Daegu, Korea

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Kyu Hyang Cho Department of Internal Medicine, College of Medicine, Yeungnam University, Daegu, Korea

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Young Kyung Bae Department of Pathology, College of Medicine, Yeungnam University, Daegu, Korea

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Seung-Soon Im Department of Physiology, Keimyung University School of Medicine, Daegu, Korea

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Kwang-Hyeon Liu College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, Korea

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In-Hwan Song Department of Anatomy, College of Medicine, Yeungnam University, Daegu, Korea

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Jae-Ryong Kim Smart-Aging Convergence Research Center, College of Medicine, Yeungnam University, Daegu, Korea
Department of Biochemistry and Molecular Biology, College of Medicine, Yeungnam University, Daegu, Korea

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In-Kyu Lee Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea

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So-Young Park Department of Physiology, College of Medicine, Yeungnam University, Daegu, Korea
Smart-Aging Convergence Research Center, College of Medicine, Yeungnam University, Daegu, Korea

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fibrosis ( Jiang et al. 2005 b , Ishigaki et al. 2007 ). Fatty acid oxidation is one of the important energy-producing pathways in the kidney, particularly in the proximal tubules ( Mount et al. 2015 ). Fatty acids are usually bound to albumin in

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-17-0453
Volume/Issue:
Volume 237: Issue 2
Free access
Amanda J Genders Institute for Mental and Physical Health and Clinical Translation (iMPACT) and Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Victoria, Australia
Institute for Health and Sport (iHeS), Victoria University, Melbourne, Victoria, Australia

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Timothy Connor Institute for Mental and Physical Health and Clinical Translation (iMPACT) and Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Victoria, Australia

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Shona Morrison Institute for Mental and Physical Health and Clinical Translation (iMPACT) and Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Victoria, Australia

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Simon T Bond Institute for Mental and Physical Health and Clinical Translation (iMPACT) and Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Victoria, Australia
Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia

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Brian G Drew Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia

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Peter J Meikle Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia

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Kirsten F Howlett Institute for Physical Activity and Nutrition (IPAN) and School of Exercise and Nutrition Science and Deakin University, Geelong, Victoria, Australia

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Sean L McGee Institute for Mental and Physical Health and Clinical Translation (iMPACT) and Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Victoria, Australia

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circulating LDL/VLDL and lipid availability for peripheral tissues. However, the reduced expression of Pgc-1α could also contribute, as hepatic PGC-1α also drives fatty acid oxidation ( Morris et al. 2012 ) and was consistent with the hepatic accumulation

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-19-0548
Volume/Issue:
Volume 246: Issue 3
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Jonathan M Mudry Section for Integrative Physiology, Section for Integrative Physiology, Department of Molecular Medicine and Surgery

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Julie Massart Section for Integrative Physiology, Section for Integrative Physiology, Department of Molecular Medicine and Surgery

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Ferenc L M Szekeres Section for Integrative Physiology, Section for Integrative Physiology, Department of Molecular Medicine and Surgery

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Anna Krook Section for Integrative Physiology, Section for Integrative Physiology, Department of Molecular Medicine and Surgery
Section for Integrative Physiology, Section for Integrative Physiology, Department of Molecular Medicine and Surgery

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of the phosphorylated form of ACC was unchanged, leading to a larger ratio of inactivated ACC. In cultured C2C12 cells overexpressing TWIST1 or TWIST2, fatty acid oxidation in vitro was unchanged. Thus if glucose utilization is increased while fatty

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-14-0474
Volume/Issue:
Volume 224: Issue 3
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Li Zhao Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Chunfang Zhu Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Meng Lu Research Center for Clinical Medicine, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Chi Chen Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Xiaomin Nie Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Buatikamu Abudukerimu Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Kun Zhang Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Zhiyuan Ning Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Yi Chen Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Jing Cheng Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Fangzhen Xia Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Ningjian Wang Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Michael D Jensen Endocrine Research Unit, Mayo Clinic, Rochester, Minnesota, USA

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Yingli Lu Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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et al . 2007 ). Fatty acid β-oxidation ratios were deduced by measuring the specific activity of 3 H 2 O. All the relative formulas are shown as follows ( Vella & Rizza 2009 ): Deposition rate of TG (dpm/g) =  3 H-TG radioactivity (dpm

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0374
Volume/Issue:
Volume 240: Issue 2
Free access
A Santillo Dipartimento di Scienze e Tecnologie Ambientali, Biologiche e Farmaceutiche, Seconda Università degli Studi di Napoli, via Vivaldi, 43, 81100 Caserta, Italy

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L Burrone Dipartimento di Scienze e Tecnologie Ambientali, Biologiche e Farmaceutiche, Seconda Università degli Studi di Napoli, via Vivaldi, 43, 81100 Caserta, Italy

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S Falvo Dipartimento di Scienze e Tecnologie Ambientali, Biologiche e Farmaceutiche, Seconda Università degli Studi di Napoli, via Vivaldi, 43, 81100 Caserta, Italy

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R Senese Dipartimento di Scienze e Tecnologie Ambientali, Biologiche e Farmaceutiche, Seconda Università degli Studi di Napoli, via Vivaldi, 43, 81100 Caserta, Italy

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A Lanni Dipartimento di Scienze e Tecnologie Ambientali, Biologiche e Farmaceutiche, Seconda Università degli Studi di Napoli, via Vivaldi, 43, 81100 Caserta, Italy

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G Chieffi Baccari Dipartimento di Scienze e Tecnologie Ambientali, Biologiche e Farmaceutiche, Seconda Università degli Studi di Napoli, via Vivaldi, 43, 81100 Caserta, Italy

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peroxisomal fatty acid oxidation respectively. Next, because T 3 stimulates fat oxidation by acting at the mitochondrial and peroxisomal levels, we studied the effect of an animal's thyroid state on the mitochondria, correlating mitochondrial activity and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0127
Volume/Issue:
Volume 219: Issue 1
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Samrin Kagdi Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

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Sulayman A Lyons Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

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Jacqueline L Beaudry Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

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in humans increased supraclavicular temperature after 6 days of GIP infusion and NEFAs during the initial 3 h of treatment while acutely lowering fatty acid oxidation ( Boer et al. 2021 ). GIPR BAT knock-out mice show an increase in mRNA UCP1 levels

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-23-0361
Volume/Issue:
Volume 261: Issue 3
Open access
G. G. MURTHY
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R. R. MODESTO
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SUMMARY

The effects of luteinizing hormone releasing hormone (LH-RH) and thyrotrophin releasing hormone (TRH) on rabbit adipose tissue were studied. LH-RH increased [14C]glucose oxidation and incorporation into fatty acids and had lipolytic activity, at the same time decreasing [14C]glucose incorporation in glyceride—glycerol fractions. TRH had no significant effect on glucose oxidation or lipolysis but decreased [14C]fatty acid synthesis and [14C]glucose incorporation into glyceride—glycerol fractions.

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.0.0620639
Volume/Issue:
Volume 62: Issue 3
Restricted access