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Saranyapin Potikanond
Saranyapin Potikanond
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Pinyada Rattanachote
Pinyada Rattanachote
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Hiranya Pintana
Hiranya Pintana
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Panan Suntornsaratoon
Panan Suntornsaratoon
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Narattaphol Charoenphandhu
Narattaphol Charoenphandhu
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Nipon Chattipakorn
Nipon Chattipakorn
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Siriporn Chattipakorn
Siriporn Chattipakorn
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Department of Pharmacology, Neurophysiology Unit, Center of Calcium and Bone Research (COCAB), Department of Physiology, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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signaling, leading to the development of obesity, insulin resistance, and type 2 diabetes mellitus ( Grossmann et al . 2009 ). Several studies have also demonstrated that a testosterone-deficient condition causes osteopenia and osteoporosis ( Dupree & Dobs
Bethany P Cummings
Bethany P Cummings
Department of Molecular Biosciences, Department of Nutrition, Department of Pediatrics, Department of Physiology, Division of Endocrinology, School of Veterinary Medicine, University of California Davis, One Shields Avenue, Davis, California 95616, USA
Department of Molecular Biosciences, Department of Nutrition, Department of Pediatrics, Department of Physiology, Division of Endocrinology, School of Veterinary Medicine, University of California Davis, One Shields Avenue, Davis, California 95616, USA
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Department of Molecular Biosciences, Department of Nutrition, Department of Pediatrics, Department of Physiology, Division of Endocrinology, School of Veterinary Medicine, University of California Davis, One Shields Avenue, Davis, California 95616, USA
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Andrew A Bremer
Andrew A Bremer
Department of Molecular Biosciences, Department of Nutrition, Department of Pediatrics, Department of Physiology, Division of Endocrinology, School of Veterinary Medicine, University of California Davis, One Shields Avenue, Davis, California 95616, USA
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Timothy J Kieffer
Timothy J Kieffer
Department of Molecular Biosciences, Department of Nutrition, Department of Pediatrics, Department of Physiology, Division of Endocrinology, School of Veterinary Medicine, University of California Davis, One Shields Avenue, Davis, California 95616, USA
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David D'Alessio
David D'Alessio
Department of Molecular Biosciences, Department of Nutrition, Department of Pediatrics, Department of Physiology, Division of Endocrinology, School of Veterinary Medicine, University of California Davis, One Shields Avenue, Davis, California 95616, USA
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Peter J Havel
Peter J Havel
Department of Molecular Biosciences, Department of Nutrition, Department of Pediatrics, Department of Physiology, Division of Endocrinology, School of Veterinary Medicine, University of California Davis, One Shields Avenue, Davis, California 95616, USA
Department of Molecular Biosciences, Department of Nutrition, Department of Pediatrics, Department of Physiology, Division of Endocrinology, School of Veterinary Medicine, University of California Davis, One Shields Avenue, Davis, California 95616, USA
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Department of Molecular Biosciences, Department of Nutrition, Department of Pediatrics, Department of Physiology, Division of Endocrinology, School of Veterinary Medicine, University of California Davis, One Shields Avenue, Davis, California 95616, USA
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levels of circulating exogenous and endogenous glucocorticoids is associated with several side effects, including insulin resistance ( Vegiopoulos & Herzig 2007 ). For example, patients with enhanced endogenous glucocorticoid production (Cushing
Brenna Osborne
Brenna Osborne
Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
Department of Pharmacology, School of Biomedical Sciences, UNSW Sydney, New South Wales, Australia
Department of Cellular and Molecular Medicine, Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Pharmacology, School of Biomedical Sciences, UNSW Sydney, New South Wales, Australia
Department of Cellular and Molecular Medicine, Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Lauren E Wright
Lauren E Wright
Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
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Amanda E Brandon
Amanda E Brandon
Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
Charles Perkins Centre, University of Sydney, New South Wales, Australia
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Charles Perkins Centre, University of Sydney, New South Wales, Australia
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Ella Stuart
Ella Stuart
Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
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Lewin Small
Lewin Small
Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
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Joris Hoeks
Joris Hoeks
NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands
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Patrick Schrauwen
Patrick Schrauwen
NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands
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David A Sinclair
David A Sinclair
Department of Genetics, Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School, Boston, Massachusetts, USA
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Magdalene K Montgomery
Magdalene K Montgomery
Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
Department of Anatomy & Physiology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia
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Department of Anatomy & Physiology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia
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Gregory J Cooney
Gregory J Cooney
Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
Charles Perkins Centre, University of Sydney, New South Wales, Australia
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Charles Perkins Centre, University of Sydney, New South Wales, Australia
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Nigel Turner
Nigel Turner
Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
Department of Pharmacology, School of Biomedical Sciences, UNSW Sydney, New South Wales, Australia
Cellular Bioenergetics Laboratory, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia
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Department of Pharmacology, School of Biomedical Sciences, UNSW Sydney, New South Wales, Australia
Cellular Bioenergetics Laboratory, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia
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Introduction Mitochondrial dysfunction has been associated with skeletal muscle insulin resistance and type 2 diabetes in humans as well as in animal models of lipid-induced insulin resistance (reviewed in Montgomery & Turner 2015 ). SIRT3 is
Alpana Mathur
Alpana Mathur
Herbal Research Laboratory, CSIR-Indian Institute of Toxicology Research, Lucknow, India
Babu Banarasi Das University, BBD City, Lucknow, India
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Babu Banarasi Das University, BBD City, Lucknow, India
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Vivek Kumar Pandey
Vivek Kumar Pandey
Herbal Research Laboratory, CSIR-Indian Institute of Toxicology Research, Lucknow, India
Academy of Scientific and Innovative Research, CSIR-IITR, Lucknow, India
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Academy of Scientific and Innovative Research, CSIR-IITR, Lucknow, India
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Poonam Kakkar
Poonam Kakkar
Herbal Research Laboratory, CSIR-Indian Institute of Toxicology Research, Lucknow, India
Babu Banarasi Das University, BBD City, Lucknow, India
Academy of Scientific and Innovative Research, CSIR-IITR, Lucknow, India
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Babu Banarasi Das University, BBD City, Lucknow, India
Academy of Scientific and Innovative Research, CSIR-IITR, Lucknow, India
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Background Type 2 diabetes (T2D), obesity and allied disorders are posing serious health problems that are reaching epidemic proportions worldwide ( Nanditha et al . 2016 ). Insulin resistance, a key feature of T2D and obesity, subdues the
Yuehui Zhang
Yuehui Zhang
Department of Obstetrics and Gynecology, Key Laboratory and Unit of Infertility in Chinese Medicine, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, China
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Min Hu
Min Hu
Department of Physiology/Endocrinology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Department of Traditional Chinese Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
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Department of Traditional Chinese Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
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Wenyan Jia
Wenyan Jia
Department of Obstetrics and Gynecology, Key Laboratory and Unit of Infertility in Chinese Medicine, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, China
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Guoqi Liu
Guoqi Liu
Department of Obstetrics and Gynecology, Key Laboratory and Unit of Infertility in Chinese Medicine, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, China
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Jiao Zhang
Jiao Zhang
Department of Acupuncture and Moxibustion, Second Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, China
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Bing Wang
Bing Wang
Department of Obstetrics and Gynecology, Key Laboratory and Unit of Infertility in Chinese Medicine, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, China
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Juan Li
Juan Li
Department of Physiology/Endocrinology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Department of Traditional Chinese Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
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Department of Traditional Chinese Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
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Peng Cui
Peng Cui
Department of Physiology/Endocrinology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Department of Gynecology, Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Department of Gynecology, Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Xin Li
Xin Li
Department of Physiology/Endocrinology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, China
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Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, China
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Susanne Lager
Susanne Lager
Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden
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Amanda Nancy Sferruzzi-Perri
Amanda Nancy Sferruzzi-Perri
Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK
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Yanhua Han
Yanhua Han
Department of Obstetrics and Gynecology, Key Laboratory and Unit of Infertility in Chinese Medicine, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, China
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Songjiang Liu
Songjiang Liu
Department of Obstetrics and Gynecology, Key Laboratory and Unit of Infertility in Chinese Medicine, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, China
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Xiaoke Wu
Xiaoke Wu
Department of Obstetrics and Gynecology, Key Laboratory and Unit of Infertility in Chinese Medicine, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, China
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Mats Brännström
Mats Brännström
Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Linus R Shao
Linus R Shao
Department of Physiology/Endocrinology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Håkan Billig
Håkan Billig
Department of Physiology/Endocrinology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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approximately 4–21% of all adolescent and reproductive-aged women and has a significant impact on their reproduction ( Lizneva et al. 2016 ). Women with PCOS often suffer from hyperandrogenism/androgen excess and insulin resistance (collectively termed; HAIR
Eriko Inoue
Eriko Inoue
Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
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Toshihiro Ichiki
Toshihiro Ichiki
Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
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Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
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Kotaro Takeda
Kotaro Takeda
Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
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Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
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Hirohide Matsuura
Hirohide Matsuura
Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
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Toru Hashimoto
Toru Hashimoto
Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
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Jiro Ikeda
Jiro Ikeda
Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
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Aya Kamiharaguchi
Aya Kamiharaguchi
Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
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Kenji Sunagawa
Kenji Sunagawa
Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
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Introduction Obesity plays a central role in the development of metabolic syndrome ( Wajchenberg 2000 ), a constellation of risk factors such as insulin resistance, dyslipidemia, and high blood pressure. Accumulation of visceral fat rather than
Camilla Alexanderson
Camilla Alexanderson
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Elias Eriksson
Elias Eriksson
Department of Physiology, Department of Pharmacology, Wallenberg Laboratory, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Göteborg University, Box 434, SE-405 30 Göteborg, Sweden
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Elisabet Stener-Victorin
Elisabet Stener-Victorin
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Malin Lönn
Malin Lönn
Department of Physiology, Department of Pharmacology, Wallenberg Laboratory, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Göteborg University, Box 434, SE-405 30 Göteborg, Sweden
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Agneta Holmäng
Agneta Holmäng
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, Recabarren et al . 2005 , King et al . 2007 ). In a recent study, we showed that an early postnatal injection of oestradiol, testosterone or dihydrotestosterone causes insulin resistance in adult female rats, and that testosterone and oestradiol exposed
Marina C Muñoz
Marina C Muñoz
Instituto de Química y Fisicoquímica Biológicas (UBA-CONICET), Cátedra de Farmacología, Laboratorio de Medicina Experimental, IQUIFIB
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Jorge F Giani
Jorge F Giani
Instituto de Química y Fisicoquímica Biológicas (UBA-CONICET), Cátedra de Farmacología, Laboratorio de Medicina Experimental, IQUIFIB
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Marcos A Mayer
Marcos A Mayer
Instituto de Química y Fisicoquímica Biológicas (UBA-CONICET), Cátedra de Farmacología, Laboratorio de Medicina Experimental, IQUIFIB
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Jorge E Toblli
Jorge E Toblli
Instituto de Química y Fisicoquímica Biológicas (UBA-CONICET), Cátedra de Farmacología, Laboratorio de Medicina Experimental, IQUIFIB
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Daniel Turyn
Daniel Turyn
Instituto de Química y Fisicoquímica Biológicas (UBA-CONICET), Cátedra de Farmacología, Laboratorio de Medicina Experimental, IQUIFIB
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Fernando P Dominici
Fernando P Dominici
Instituto de Química y Fisicoquímica Biológicas (UBA-CONICET), Cátedra de Farmacología, Laboratorio de Medicina Experimental, IQUIFIB
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resistance as well as in certain types of insulin-resistant states in humans ( Li et al . 2002 , Johnston et al . 2003 , Taniguchi et al . 2006 , Youngren 2007 ). IR Ser994 is one of the potential inhibitory sites of the IR kinase as determined by site
Louis Potier
Louis Potier
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Ludovic Waeckel
Ludovic Waeckel
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Fréderic Fumeron
Fréderic Fumeron
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Sophie Bodin
Sophie Bodin
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Marinos Fysekidis
Marinos Fysekidis
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Catherine Chollet
Catherine Chollet
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Naima Bellili
Naima Bellili
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Fabrice Bonnet
Fabrice Bonnet
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Gaëlle Gusto
Gaëlle Gusto
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Gilberto Velho
Gilberto Velho
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Michel Marre
Michel Marre
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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François Alhenc-Gelas
François Alhenc-Gelas
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Ronan Roussel
Ronan Roussel
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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Nadine Bouby
Nadine Bouby
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
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the DESIR study group
the DESIR study group
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Introduction The prevalence of obesity is increasing worldwide, together with the metabolic and cardiovascular complications of the condition, related in part to insulin resistance ( Ogden et al . 2012 ). Intervention trials aimed at preventing
Cho-Rong Bae
Cho-Rong Bae
Frontier Science Research Center, Department of Food Science and Human Nutrition, Faculty of Food Science and Nutrition, University of Miyazaki, Miyazaki 889-1692, Japan
Frontier Science Research Center, Department of Food Science and Human Nutrition, Faculty of Food Science and Nutrition, University of Miyazaki, Miyazaki 889-1692, Japan
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Frontier Science Research Center, Department of Food Science and Human Nutrition, Faculty of Food Science and Nutrition, University of Miyazaki, Miyazaki 889-1692, Japan
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Kazuya Hasegawa
Kazuya Hasegawa
Frontier Science Research Center, Department of Food Science and Human Nutrition, Faculty of Food Science and Nutrition, University of Miyazaki, Miyazaki 889-1692, Japan
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Sayaka Akieda-Asai
Sayaka Akieda-Asai
Frontier Science Research Center, Department of Food Science and Human Nutrition, Faculty of Food Science and Nutrition, University of Miyazaki, Miyazaki 889-1692, Japan
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Yurie Kawasaki
Yurie Kawasaki
Frontier Science Research Center, Department of Food Science and Human Nutrition, Faculty of Food Science and Nutrition, University of Miyazaki, Miyazaki 889-1692, Japan
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Kazuyo Senba
Kazuyo Senba
Frontier Science Research Center, Department of Food Science and Human Nutrition, Faculty of Food Science and Nutrition, University of Miyazaki, Miyazaki 889-1692, Japan
Frontier Science Research Center, Department of Food Science and Human Nutrition, Faculty of Food Science and Nutrition, University of Miyazaki, Miyazaki 889-1692, Japan
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Frontier Science Research Center, Department of Food Science and Human Nutrition, Faculty of Food Science and Nutrition, University of Miyazaki, Miyazaki 889-1692, Japan
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Youn-Soo Cha
Youn-Soo Cha
Frontier Science Research Center, Department of Food Science and Human Nutrition, Faculty of Food Science and Nutrition, University of Miyazaki, Miyazaki 889-1692, Japan
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Yukari Date
Yukari Date
Frontier Science Research Center, Department of Food Science and Human Nutrition, Faculty of Food Science and Nutrition, University of Miyazaki, Miyazaki 889-1692, Japan
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Introduction Insulin resistance is a major factor in the pathogenesis of type 2 diabetes arising from a prediabetic condition and an important complication of obesity ( Shepherd & Kahn 1999 ). Although obesity is defined as extreme body fat and is
