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Hershel Raff Endocrine Research Laboratory, Aurora St Luke’s Medical Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53215, USA
Center for Neuropharmacology and Neurosciences, Albany Medical College, Albany, New York 12208, USA

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Lauren Jacobson Endocrine Research Laboratory, Aurora St Luke’s Medical Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53215, USA
Center for Neuropharmacology and Neurosciences, Albany Medical College, Albany, New York 12208, USA

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adenohypophysis following exposure to high altitude. Neuroscience Letters 318 125 –128. Kent C & Parker KG 1993 Effects of ACTH and aminoglutethimide on the catecholamine content and chromaffin cell morphology of the adrenal

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Christoffer Clemmensen
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Sanela Smajilovic
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Andreas N Madsen Department of Drug Design and Pharmacology, Department of Neuroscience and Pharmacology, Center for Integrated Molecular Brain Imaging, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark

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Anders B Klein Department of Drug Design and Pharmacology, Department of Neuroscience and Pharmacology, Center for Integrated Molecular Brain Imaging, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark

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Birgitte Holst Department of Drug Design and Pharmacology, Department of Neuroscience and Pharmacology, Center for Integrated Molecular Brain Imaging, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark

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Hans Bräuner-Osborne
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Coolen LM Strauss R Jackman A Clegg DJ Seeley RJ Woods SC 2002 The catabolic action of insulin in the brain is mediated by melanocortins . Journal of Neuroscience 22 9048 – 9052 . Bjorbaek C Elmquist JK Frantz JD Shoelson SE

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Mark O Huising Department of Animal Physiology, Institute for Neuroscience, Radboud University, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands
Department of Cell Biology and Immunology, Wageningen University, Wageningen, The Netherlands

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Corine P Kruiswijk Department of Animal Physiology, Institute for Neuroscience, Radboud University, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands
Department of Cell Biology and Immunology, Wageningen University, Wageningen, The Netherlands

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Gert Flik Department of Animal Physiology, Institute for Neuroscience, Radboud University, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands
Department of Cell Biology and Immunology, Wageningen University, Wageningen, The Netherlands

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heteromeric ligand for the CNTF receptor complex. Nature Neuroscience 3 867 –872. Ernst M & Jenkins BJ 2004 Acquiring signalling specificity from the cytokine receptor gp130. Trends in Genetics 20 23 –32

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Iain R Thompson Endocrine Signalling Group, Barts and the London School of Medicine and Dentistry, Department of Medicine, Cardiovascular and Inflammation Group, Laboratory for Integrated Neurosciences and Endocrinology, Veterinary Basic Sciences, Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK

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Annisa N Chand Endocrine Signalling Group, Barts and the London School of Medicine and Dentistry, Department of Medicine, Cardiovascular and Inflammation Group, Laboratory for Integrated Neurosciences and Endocrinology, Veterinary Basic Sciences, Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK

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Kim C Jonas Endocrine Signalling Group, Barts and the London School of Medicine and Dentistry, Department of Medicine, Cardiovascular and Inflammation Group, Laboratory for Integrated Neurosciences and Endocrinology, Veterinary Basic Sciences, Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK

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Jacky M Burrin Endocrine Signalling Group, Barts and the London School of Medicine and Dentistry, Department of Medicine, Cardiovascular and Inflammation Group, Laboratory for Integrated Neurosciences and Endocrinology, Veterinary Basic Sciences, Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK

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Mark E Steinhelper Endocrine Signalling Group, Barts and the London School of Medicine and Dentistry, Department of Medicine, Cardiovascular and Inflammation Group, Laboratory for Integrated Neurosciences and Endocrinology, Veterinary Basic Sciences, Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK

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Caroline P Wheeler-Jones Endocrine Signalling Group, Barts and the London School of Medicine and Dentistry, Department of Medicine, Cardiovascular and Inflammation Group, Laboratory for Integrated Neurosciences and Endocrinology, Veterinary Basic Sciences, Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK

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Craig A McArdle Endocrine Signalling Group, Barts and the London School of Medicine and Dentistry, Department of Medicine, Cardiovascular and Inflammation Group, Laboratory for Integrated Neurosciences and Endocrinology, Veterinary Basic Sciences, Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK

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Robert C Fowkes Endocrine Signalling Group, Barts and the London School of Medicine and Dentistry, Department of Medicine, Cardiovascular and Inflammation Group, Laboratory for Integrated Neurosciences and Endocrinology, Veterinary Basic Sciences, Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK
Endocrine Signalling Group, Barts and the London School of Medicine and Dentistry, Department of Medicine, Cardiovascular and Inflammation Group, Laboratory for Integrated Neurosciences and Endocrinology, Veterinary Basic Sciences, Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK
Endocrine Signalling Group, Barts and the London School of Medicine and Dentistry, Department of Medicine, Cardiovascular and Inflammation Group, Laboratory for Integrated Neurosciences and Endocrinology, Veterinary Basic Sciences, Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK

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2002 Atrial natriuretic peptide type C induces a cell-cycle switch from proliferation to differentiation in brain-derived neurotrophic factor- or nerve growth factor-primed olfactory receptor neurons . Journal of Neuroscience 22 5536 – 5551

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J Svensson Research Centre for Endocrinology and Metabolism, Department of Internal Medicine, Gröna Stråket 8, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden
Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden

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M Diez Research Centre for Endocrinology and Metabolism, Department of Internal Medicine, Gröna Stråket 8, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden
Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden

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J Engel Research Centre for Endocrinology and Metabolism, Department of Internal Medicine, Gröna Stråket 8, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden
Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden

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C Wass Research Centre for Endocrinology and Metabolism, Department of Internal Medicine, Gröna Stråket 8, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden
Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden

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Å Tivesten Research Centre for Endocrinology and Metabolism, Department of Internal Medicine, Gröna Stråket 8, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden
Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden

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J-O Jansson Research Centre for Endocrinology and Metabolism, Department of Internal Medicine, Gröna Stråket 8, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden
Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden

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O Isaksson Research Centre for Endocrinology and Metabolism, Department of Internal Medicine, Gröna Stråket 8, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden
Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden

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T Archer Research Centre for Endocrinology and Metabolism, Department of Internal Medicine, Gröna Stråket 8, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden
Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden

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T Hökfelt Research Centre for Endocrinology and Metabolism, Department of Internal Medicine, Gröna Stråket 8, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden
Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden

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C Ohlsson Research Centre for Endocrinology and Metabolism, Department of Internal Medicine, Gröna Stråket 8, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden
Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden

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Unrestricted Bristol-Myers Squibb Neuroscience Grant. The authors are grateful to Professor Sven Ove Ögren and Eugenia Kuteeva for valuable advice concerning experiments with the Morris swim maze. They are also grateful to Maud Petersson, Anna-Lena Jirestedt

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Chunxiao Qi Department of Neurobiology, Hebei Medical University, Shijiazhuang, People’s Republic of China
Department of Human Anatomy, Hebei Medical University, Shijiazhuang, People’s Republic of China

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Xiaoming Ji Department of Neurobiology, Hebei Medical University, Shijiazhuang, People’s Republic of China

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Guoliang Zhang Department of Human Anatomy, Hebei Medical University, Shijiazhuang, People’s Republic of China

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Yunxiao Kang Department of Neurobiology, Hebei Medical University, Shijiazhuang, People’s Republic of China

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Yuanxiang Huang Grade 2015 Eight-year Clinical Medicine Program, School of Basic Medical Sciences, Hebei Medical University, Shijiazhuang, People’s Republic of China

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Rui Cui Department of Human Anatomy, Hebei Medical University, Shijiazhuang, People’s Republic of China

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Shuangcheng Li Department of Human Anatomy, Hebei Medical University, Shijiazhuang, People’s Republic of China

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Huixian Cui Department of Human Anatomy, Hebei Medical University, Shijiazhuang, People’s Republic of China
Neuroscience Research Center, Hebei Medical University, Shijiazhuang, People’s Republic of China

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Geming Shi Department of Neurobiology, Hebei Medical University, Shijiazhuang, People’s Republic of China
Department of Human Anatomy, Hebei Medical University, Shijiazhuang, People’s Republic of China
Neuroscience Research Center, Hebei Medical University, Shijiazhuang, People’s Republic of China

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not used in the study. All of the experimental procedures followed the rules in the ‘Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research’ and approved by the Committee of Ethics on Animal Experiments at Hebei Medical

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Jordan E Hamden Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada
Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada

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Katherine M Gray Department of Psychology, University of British Columbia, Vancouver, British Columbia, Canada
Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

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Melody Salehzadeh Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada
Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada

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Kiran K Soma Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada
Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada
Department of Psychology, University of British Columbia, Vancouver, British Columbia, Canada
Graduate Program in Neuroscience, University of British Columbia, Vancouver, British Columbia, Canada

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Charting of type II glucocorticoid receptor-like immunoreactivity in the rat central nervous system . Neuroscience 39 579 – 604 . ( https://doi.org/10.1016/0306-4522(9090244-x ) 1711170 10.1016/0306-4522(90)90244-X Bath KG 2020 Synthesizing views to

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Marta Lantero Rodriguez Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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Maaike Schilperoort Department of Medicine, Division of Endocrinology and Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands

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Inger Johansson Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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Elin Svedlund Eriksson Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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Vilborg Palsdottir Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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Jan Kroon Department of Medicine, Division of Endocrinology and Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands

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Marcus Henricsson Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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Sander Kooijman Department of Medicine, Division of Endocrinology and Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands

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Mia Ericson Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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Jan Borén Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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Claes Ohlsson Center for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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John-Olov Jansson Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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Malin C Levin Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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Patrick C N Rensen Department of Medicine, Division of Endocrinology and Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands

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Åsa Tivesten Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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– 154 . ( https://doi.org/10.1111/cen.12620 ) Ermis N Deniz F Kepez A Kara B Azal O Kutlu M 2010 Heart rate variability of young men with idiopathic hypogonadotropic hypogonadism . Autonomic Neuroscience: Basic and Clinical 152 84

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Candice Marion Université de Paris, INSERM UMR S-1124, CNRS ERL3649, Paris, France

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Philippe Zizzari Université de Bordeaux, Neurocentre Magendie, INSERM U1215, Bordeaux, France

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Raphael G P Denis Université de Paris, BFA, UMR 8251, CNRS, Paris, France

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Rim Hassouna Université de Paris, BFA, UMR 8251, CNRS, Paris, France

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Yacine Chebani Université de Paris, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, Laboratoire de Physiopathologie des Maladies Psychiatriques, Paris, France

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Thierry Leste-Lasserre Université de Bordeaux, Neurocentre Magendie, INSERM U1215, Bordeaux, France

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Hélène Doat Université de Bordeaux, Neurocentre Magendie, INSERM U1215, Bordeaux, France

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Gwenaëlle Le Pen Université de Paris, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, Laboratoire de Physiopathologie des Maladies Psychiatriques, Paris, France

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Daniela Cota Université de Bordeaux, Neurocentre Magendie, INSERM U1215, Bordeaux, France

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Florence Noble Université de Paris, INSERM UMR S-1124, CNRS ERL3649, Paris, France

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Serge Luquet Université de Paris, BFA, UMR 8251, CNRS, Paris, France

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Jacques Pantel Université de Paris, INSERM UMR S-1124, CNRS ERL3649, Paris, France

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, Medical College of Wisconsin), to the animal core and PhenoBrain facilities of the Institute of Psychiatry and Neuroscience of Paris (INSERM UMR S-1266 | Université de Paris), the animal core facility of BioMedTech (INSERM US36 | CNRS UMS2009 | Université

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Rui Gao Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK

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Samuel Acreman Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK
Department of Physiology, Institute of Neuroscience and Physiology, Metabolic Research Unit, University of Gothenburg, Göteborg, Sweden

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Jinfang Ma Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK

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Fernando Abdulkader Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil

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Anna Wendt Department of Clinical Sciences Malmö, Islet Cell Exocytosis, Lund University Diabetes Centre, Lund University, Malmö, Sweden

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Quan Zhang Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK
CNC - Center for Neuroscience and Cell Biology, CIBB - Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra, Portugal

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Amperometric detection of single vesicle acetylcholine release events from an artificial cell . ACS Chemical Neuroscience 6 181 – 188 . ( https://doi.org/10.1021/cn5002667 ) Kimball CP & Murlin JR 1923 Aqueous extracts of pancreas: III . Journal of

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