Filter

Refine by date

—

Refine by collections

Refine by access

  • Print
  • Save

Search Results

You are looking at 41 - 50 of 5,839 items for :

  • Refine by access: All content x
Clear All
D. J. HILL
Search for other papers by D. J. HILL in
Google Scholar
PubMed Close
,
M. J. O. FRANCIS
Search for other papers by M. J. O. FRANCIS in
Google Scholar
PubMed Close
, and
R. D. G. MILNER
Search for other papers by R. D. G. MILNER in
Google Scholar
PubMed Close

Rat prolactin at a concentration of 50 ng/ml perfusion medium stimulated the production of somatomedin-like activity (SLA) from the perfused liver of normal rats. The effect was demonstrable in perfusions performed at 11.00 h in which rat prolactin caused a mean (±s.e.m.) increase in the uptake of [35S]sulphate into rat costal cartilage in vitro of 64 ± 14% in comparison with controls, but at 15.00 h no effect was observed. No effect of rat prolactin on hypophysectomized rat liver was detectable at 11.00 h.

Hypophysectomized and sham-operated rats were given five intravenous injections of 50 μg rat prolactin or a similar volume of hormone solvent at 12 h intervals. Plasma somatomedin activity (SMA) and cartilage metabolism, measured by the uptake of radioactive sulphate and thymidine by costal cartilage in vitro, were similar in hypophysectomized animals given rat prolactin or hormone solvent. Sham-operated rats given rat prolactin showed a significant increase of plasma SMA and cartilage metabolism compared with control animals.

The production of SLA by rat liver in response to rat prolactin may be related to the density of specific hepatic lactogenic receptors, since these are absent or present only in low numbers in hypophysectomized animals.

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.0.0750137
Volume/Issue:
Volume 75: Issue 1
Restricted access
O Kosti Centre for Endocrinology, William Harvey Research Institute, Barts and The London, Queen Mary’s School of Medicine and Dentistry, QMUL, First Floor, John Vane Science Centre, Charterhouse Square, London EC1 M 6BQ, UK
Metabolic and Clinical Trials Unit, Department of Mental Health Sciences, Royal Free and University College Medical School, UCL, London, UK

Search for other papers by O Kosti in
Google Scholar
PubMed Close
,
P W Raven Centre for Endocrinology, William Harvey Research Institute, Barts and The London, Queen Mary’s School of Medicine and Dentistry, QMUL, First Floor, John Vane Science Centre, Charterhouse Square, London EC1 M 6BQ, UK
Metabolic and Clinical Trials Unit, Department of Mental Health Sciences, Royal Free and University College Medical School, UCL, London, UK

Search for other papers by P W Raven in
Google Scholar
PubMed Close
,
D Renshaw Centre for Endocrinology, William Harvey Research Institute, Barts and The London, Queen Mary’s School of Medicine and Dentistry, QMUL, First Floor, John Vane Science Centre, Charterhouse Square, London EC1 M 6BQ, UK
Metabolic and Clinical Trials Unit, Department of Mental Health Sciences, Royal Free and University College Medical School, UCL, London, UK

Search for other papers by D Renshaw in
Google Scholar
PubMed Close
, and
J P Hinson Centre for Endocrinology, William Harvey Research Institute, Barts and The London, Queen Mary’s School of Medicine and Dentistry, QMUL, First Floor, John Vane Science Centre, Charterhouse Square, London EC1 M 6BQ, UK
Metabolic and Clinical Trials Unit, Department of Mental Health Sciences, Royal Free and University College Medical School, UCL, London, UK

Search for other papers by J P Hinson in
Google Scholar
PubMed Close

Introduction The Maudsley reactive (MR) and nonreactive (MNR) rat strains were originally selected for differences in open-field defecation, an action reflecting ‘fearfulness’ ( Broadhurst 1957 ). Since MRs defecate the most, while

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06638
Volume/Issue:
Volume 189: Issue 2
Free access
Hiroki Saito
Search for other papers by Hiroki Saito in
Google Scholar
PubMed Close
,
Tomoya Nakamachi Department of Pharmacology, Department of Anatomy, Department of Clinical Pharmacy and Pharmacology, Department of Internal Medicine, Department of Molecular Pharmacology, Graduate School of Medical and Dental Science, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan

Search for other papers by Tomoya Nakamachi in
Google Scholar
PubMed Close
,
Kazuhiko Inoue
Search for other papers by Kazuhiko Inoue in
Google Scholar
PubMed Close
,
Ryuji Ikeda Department of Pharmacology, Department of Anatomy, Department of Clinical Pharmacy and Pharmacology, Department of Internal Medicine, Department of Molecular Pharmacology, Graduate School of Medical and Dental Science, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan

Search for other papers by Ryuji Ikeda in
Google Scholar
PubMed Close
,
Kazuo Kitamura Department of Pharmacology, Department of Anatomy, Department of Clinical Pharmacy and Pharmacology, Department of Internal Medicine, Department of Molecular Pharmacology, Graduate School of Medical and Dental Science, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan

Search for other papers by Kazuo Kitamura in
Google Scholar
PubMed Close
,
Naoto Minamino Department of Pharmacology, Department of Anatomy, Department of Clinical Pharmacy and Pharmacology, Department of Internal Medicine, Department of Molecular Pharmacology, Graduate School of Medical and Dental Science, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan

Search for other papers by Naoto Minamino in
Google Scholar
PubMed Close
,
Seiji Shioda Department of Pharmacology, Department of Anatomy, Department of Clinical Pharmacy and Pharmacology, Department of Internal Medicine, Department of Molecular Pharmacology, Graduate School of Medical and Dental Science, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan

Search for other papers by Seiji Shioda in
Google Scholar
PubMed Close
, and
Atsuro Miyata
Search for other papers by Atsuro Miyata in
Google Scholar
PubMed Close

been detected in rat gastrointestinal tissues, spinal cord, pancreas, pituitary gland, and several brain areas ( Ohki-Hamazaki 2000 ). NMB binds to its receptor (NMBR) – expressed in mouse brain, esophagus, intestine, testis, and uterus – to regulate

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0488
Volume/Issue:
Volume 217: Issue 2
Free access
Kouki Mori Division of Nephrology, Endocrinology and Vascular Medicine and
Division of Rheumatology and Hematology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan

Search for other papers by Kouki Mori in
Google Scholar
PubMed Close
,
Katsumi Yoshida Division of Nephrology, Endocrinology and Vascular Medicine and
Division of Rheumatology and Hematology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan

Search for other papers by Katsumi Yoshida in
Google Scholar
PubMed Close
,
Ayumi Komatsu Division of Nephrology, Endocrinology and Vascular Medicine and
Division of Rheumatology and Hematology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan

Search for other papers by Ayumi Komatsu in
Google Scholar
PubMed Close
,
Jun-ichi Tani Division of Nephrology, Endocrinology and Vascular Medicine and
Division of Rheumatology and Hematology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan

Search for other papers by Jun-ichi Tani in
Google Scholar
PubMed Close
,
Yoshinori Nakagawa Division of Nephrology, Endocrinology and Vascular Medicine and
Division of Rheumatology and Hematology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan

Search for other papers by Yoshinori Nakagawa in
Google Scholar
PubMed Close
,
Saeko Hoshikawa Division of Nephrology, Endocrinology and Vascular Medicine and
Division of Rheumatology and Hematology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan

Search for other papers by Saeko Hoshikawa in
Google Scholar
PubMed Close
, and
Sadayoshi Ito Division of Nephrology, Endocrinology and Vascular Medicine and
Division of Rheumatology and Hematology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan

Search for other papers by Sadayoshi Ito in
Google Scholar
PubMed Close

augments interferon-γ (IFNγ)-induced class II major histocompatibility complex (MHC) antigen expression ( Weetman & Rees 1988 , Zakarija et al. 1988 ). In FRTL-5 rat thyroid cells, TNFα induces interferon regulatory factor-1 ( Mori et al. 1999 ), which

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.05887
Volume/Issue:
Volume 187: Issue 1
Free access
J Varayoud Laboratorio de Endocrinología y Tumores Hormonodependientes, School of Biochemistry and Biological Sciences, Universidad Nacional del Litoral, C C 242, Santa Fe, Argentina

Search for other papers by J Varayoud in
Google Scholar
PubMed Close
,
J G Ramos Laboratorio de Endocrinología y Tumores Hormonodependientes, School of Biochemistry and Biological Sciences, Universidad Nacional del Litoral, C C 242, Santa Fe, Argentina

Search for other papers by J G Ramos in
Google Scholar
PubMed Close
,
L Monje Laboratorio de Endocrinología y Tumores Hormonodependientes, School of Biochemistry and Biological Sciences, Universidad Nacional del Litoral, C C 242, Santa Fe, Argentina

Search for other papers by L Monje in
Google Scholar
PubMed Close
,
V Bosquiazzo Laboratorio de Endocrinología y Tumores Hormonodependientes, School of Biochemistry and Biological Sciences, Universidad Nacional del Litoral, C C 242, Santa Fe, Argentina

Search for other papers by V Bosquiazzo in
Google Scholar
PubMed Close
,
M Muñoz-de-Toro Laboratorio de Endocrinología y Tumores Hormonodependientes, School of Biochemistry and Biological Sciences, Universidad Nacional del Litoral, C C 242, Santa Fe, Argentina

Search for other papers by M Muñoz-de-Toro in
Google Scholar
PubMed Close
, and
E H Luque Laboratorio de Endocrinología y Tumores Hormonodependientes, School of Biochemistry and Biological Sciences, Universidad Nacional del Litoral, C C 242, Santa Fe, Argentina

Search for other papers by E H Luque in
Google Scholar
PubMed Close

activating protein-1 (AP-1) sites, depending upon the structural properties of the ligand ( Paech et al. 1997 ). The rat uterus, a major target tissue for ovarian steroids, has served as an excellent model for studying hormonal regulation of ERα

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06099
Volume/Issue:
Volume 186: Issue 1
Free access
T Sakurai Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Science, Hachioji, Horinouchi, 1432-1, Tokyo, 192-0392, Japan

Search for other papers by T Sakurai in
Google Scholar
PubMed Close
,
K Tamura Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Science, Hachioji, Horinouchi, 1432-1, Tokyo, 192-0392, Japan

Search for other papers by K Tamura in
Google Scholar
PubMed Close
, and
H Kogo Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Science, Hachioji, Horinouchi, 1432-1, Tokyo, 192-0392, Japan

Search for other papers by H Kogo in
Google Scholar
PubMed Close

. 1998 ). In addition, PGE 2 reverses the inhibition of in vitro angiogenesis of rat aortic endothelial cells that is caused by the COX-II inhibitor NS-398 ( Jones et al. 1999 ). We recently found that the activity of COX-II may be related to the

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.05629
Volume/Issue:
Volume 183: Issue 3
Free access
Mehmet Uzumcu Department of Animal Sciences, School of Environmental and Biological Sciences, Rutgers, The State University of New Jersey, 84 Lipman Drive, New Brunswick, New Jersey 08901-8525, USA

Search for other papers by Mehmet Uzumcu in
Google Scholar
PubMed Close
,
Peter E Kuhn Department of Animal Sciences, School of Environmental and Biological Sciences, Rutgers, The State University of New Jersey, 84 Lipman Drive, New Brunswick, New Jersey 08901-8525, USA

Search for other papers by Peter E Kuhn in
Google Scholar
PubMed Close
,
Jason E Marano Department of Animal Sciences, School of Environmental and Biological Sciences, Rutgers, The State University of New Jersey, 84 Lipman Drive, New Brunswick, New Jersey 08901-8525, USA

Search for other papers by Jason E Marano in
Google Scholar
PubMed Close
,
AnnMarie E Armenti Department of Animal Sciences, School of Environmental and Biological Sciences, Rutgers, The State University of New Jersey, 84 Lipman Drive, New Brunswick, New Jersey 08901-8525, USA

Search for other papers by AnnMarie E Armenti in
Google Scholar
PubMed Close
, and
Lisa Passantino Department of Animal Sciences, School of Environmental and Biological Sciences, Rutgers, The State University of New Jersey, 84 Lipman Drive, New Brunswick, New Jersey 08901-8525, USA

Search for other papers by Lisa Passantino in
Google Scholar
PubMed Close

10) exposure to MXC on pre-pubertal (P20) ovarian folliculogenesis and AMH production in the ovary has not been studied. The objective of this study was to examine the effect of the estrogenic endocrine disruptor MXC on the rat ovary when

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06592
Volume/Issue:
Volume 191: Issue 3
Free access
Binbin Guan Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Department of Endocrinology and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P R China
Department of Endocrinology, FuJian Union hospital, Fuzhou, P R China

Search for other papers by Binbin Guan in
Google Scholar
PubMed Close
,
Wenyi Li Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Department of Endocrinology and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P R China

Search for other papers by Wenyi Li in
Google Scholar
PubMed Close
,
Fengying Li Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Department of Endocrinology and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P R China

Search for other papers by Fengying Li in
Google Scholar
PubMed Close
,
Yun Xie Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Department of Endocrinology and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P R China

Search for other papers by Yun Xie in
Google Scholar
PubMed Close
,
Qicheng Ni Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Department of Endocrinology and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P R China

Search for other papers by Qicheng Ni in
Google Scholar
PubMed Close
,
Yanyun Gu Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Department of Endocrinology and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P R China

Search for other papers by Yanyun Gu in
Google Scholar
PubMed Close
,
Xiaoying Li Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Department of Endocrinology and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P R China

Search for other papers by Xiaoying Li in
Google Scholar
PubMed Close
,
Qidi Wang Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Department of Endocrinology and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P R China

Search for other papers by Qidi Wang in
Google Scholar
PubMed Close
,
Hongli Zhang Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Department of Endocrinology and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P R China

Search for other papers by Hongli Zhang in
Google Scholar
PubMed Close
, and
Guang Ning Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Department of Endocrinology and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P R China

Search for other papers by Guang Ning in
Google Scholar
PubMed Close

, Metukuri et al . 2012 , Zhang et al . 2012 ). In rat and mouse models, glucose infusion in vivo also results in an approximately 50% increase in β-cell proliferation ( Bonner-Weir et al . 1989 , Alonso et al . 2007 , Zhang et al . 2012 ). Glucose

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-15-0535
Volume/Issue:
Volume 229: Issue 2
Free access
Jia Fang Wang Lawson Health Research Institute, Medicine, Paediatrics, St Joseph's Health Care, 268 Grosvenor Street, Room H404, London, Ontario, Canada N6A 4V2 Departments of

Search for other papers by Jia Fang Wang in
Google Scholar
PubMed Close
and
David J Hill Lawson Health Research Institute, Medicine, Paediatrics, St Joseph's Health Care, 268 Grosvenor Street, Room H404, London, Ontario, Canada N6A 4V2 Departments of
Lawson Health Research Institute, Medicine, Paediatrics, St Joseph's Health Care, 268 Grosvenor Street, Room H404, London, Ontario, Canada N6A 4V2 Departments of
Lawson Health Research Institute, Medicine, Paediatrics, St Joseph's Health Care, 268 Grosvenor Street, Room H404, London, Ontario, Canada N6A 4V2 Departments of
Lawson Health Research Institute, Medicine, Paediatrics, St Joseph's Health Care, 268 Grosvenor Street, Room H404, London, Ontario, Canada N6A 4V2 Departments of

Search for other papers by David J Hill in
Google Scholar
PubMed Close

Introduction Both islet endocrine cells and acinar tissue develop from pancreatic epithelium cells during the fetal and neonatal development of the rat, and in the human fetus ( Cerf 2006 , Murtaugh 2007 ). The initial development of both lineages

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0296
Volume/Issue:
Volume 201: Issue 1
Free access
S Peña Center for Neurobiochemical studies in Endocrine Diseases, Laboratory of Neurobiochemistry, Department of Biochemistry and Molecular Biology, Faculty of Chemistry and Pharmaceutical Sciences, Universidad de Chile, Santiago, Chile

Search for other papers by S Peña in
Google Scholar
PubMed Close
,
M Rubio Center for Neurobiochemical studies in Endocrine Diseases, Laboratory of Neurobiochemistry, Department of Biochemistry and Molecular Biology, Faculty of Chemistry and Pharmaceutical Sciences, Universidad de Chile, Santiago, Chile

Search for other papers by M Rubio in
Google Scholar
PubMed Close
,
C Vargas Center for Neurobiochemical studies in Endocrine Diseases, Laboratory of Neurobiochemistry, Department of Biochemistry and Molecular Biology, Faculty of Chemistry and Pharmaceutical Sciences, Universidad de Chile, Santiago, Chile

Search for other papers by C Vargas in
Google Scholar
PubMed Close
,
C Alanis Center for Neurobiochemical studies in Endocrine Diseases, Laboratory of Neurobiochemistry, Department of Biochemistry and Molecular Biology, Faculty of Chemistry and Pharmaceutical Sciences, Universidad de Chile, Santiago, Chile

Search for other papers by C Alanis in
Google Scholar
PubMed Close
, and
AH Paredes Center for Neurobiochemical studies in Endocrine Diseases, Laboratory of Neurobiochemistry, Department of Biochemistry and Molecular Biology, Faculty of Chemistry and Pharmaceutical Sciences, Universidad de Chile, Santiago, Chile

Search for other papers by AH Paredes in
Google Scholar
PubMed Close

cumulus–oocyte complexes, indicating that it directly influences oocyte development ( Mo et al. 2014 ). Moreover, LIF stimulates the transition from primordial to primary follicle and supports primordial follicle viability in rat, murine and goat ovary

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-22-0255
Volume/Issue:
Volume 258: Issue 1
Restricted access