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Michael C Velarde Institute of Biology, University of the Philippines Diliman, Quezon City, Philippines
Buck Institute for Research on Aging, Novato, California, USA

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Ramkumar Menon Department of Obstetrics and Gynecology, University of Texas Medical Branch at Galveston, Galveston, Texas, USA
Department of Clinical Medicine and Obstetrics and Gynecology, Aarhus University, Aarhus, Denmark

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( Maurer & Foote 1971 , Gosden & Fowler 1979 ). While the underlying cause for the age-dependent effect on fetal deaths is still unclear, it is hypothesized that impaired decidualization and uterine–embryo crosstalk are partly responsible for the perinatal

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-16-0018
Volume/Issue:
Volume 230: Issue 2
Free access
Pasquale Florio Chair of Obstetrics and Gynaecology, Department of Paediatrics, Obstetrics and Reproductive Medicine and
Department of Human Pathology and Oncology, University of Siena, Policlinico ‘Le Scotte’ Viale Bracci, 53100 Siena, Italy

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Giulia De Falco Chair of Obstetrics and Gynaecology, Department of Paediatrics, Obstetrics and Reproductive Medicine and
Department of Human Pathology and Oncology, University of Siena, Policlinico ‘Le Scotte’ Viale Bracci, 53100 Siena, Italy

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Eleonora Leucci Chair of Obstetrics and Gynaecology, Department of Paediatrics, Obstetrics and Reproductive Medicine and
Department of Human Pathology and Oncology, University of Siena, Policlinico ‘Le Scotte’ Viale Bracci, 53100 Siena, Italy

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Michela Torricelli Chair of Obstetrics and Gynaecology, Department of Paediatrics, Obstetrics and Reproductive Medicine and
Department of Human Pathology and Oncology, University of Siena, Policlinico ‘Le Scotte’ Viale Bracci, 53100 Siena, Italy

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Paulo B Torres Chair of Obstetrics and Gynaecology, Department of Paediatrics, Obstetrics and Reproductive Medicine and
Department of Human Pathology and Oncology, University of Siena, Policlinico ‘Le Scotte’ Viale Bracci, 53100 Siena, Italy

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Paolo Toti Chair of Obstetrics and Gynaecology, Department of Paediatrics, Obstetrics and Reproductive Medicine and
Department of Human Pathology and Oncology, University of Siena, Policlinico ‘Le Scotte’ Viale Bracci, 53100 Siena, Italy

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Arianna Dell’Anna Chair of Obstetrics and Gynaecology, Department of Paediatrics, Obstetrics and Reproductive Medicine and
Department of Human Pathology and Oncology, University of Siena, Policlinico ‘Le Scotte’ Viale Bracci, 53100 Siena, Italy

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Ennio Tiso Chair of Obstetrics and Gynaecology, Department of Paediatrics, Obstetrics and Reproductive Medicine and
Department of Human Pathology and Oncology, University of Siena, Policlinico ‘Le Scotte’ Viale Bracci, 53100 Siena, Italy

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Rosa Santopietro Chair of Obstetrics and Gynaecology, Department of Paediatrics, Obstetrics and Reproductive Medicine and
Department of Human Pathology and Oncology, University of Siena, Policlinico ‘Le Scotte’ Viale Bracci, 53100 Siena, Italy

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Lorenzo Leoncini Chair of Obstetrics and Gynaecology, Department of Paediatrics, Obstetrics and Reproductive Medicine and
Department of Human Pathology and Oncology, University of Siena, Policlinico ‘Le Scotte’ Viale Bracci, 53100 Siena, Italy

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Felice Petraglia Chair of Obstetrics and Gynaecology, Department of Paediatrics, Obstetrics and Reproductive Medicine and
Department of Human Pathology and Oncology, University of Siena, Policlinico ‘Le Scotte’ Viale Bracci, 53100 Siena, Italy

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demonstrated differentiating activity, since those cells undergo decidualization ( Ferrari et al. 1995 ). Furthermore, the activation of CRF-R1 receptor subtype, which is expressed under basal conditions by a tumor cell line derived from the human endometrium

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06726
Volume/Issue:
Volume 190: Issue 1
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C Dosiou
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A E Hamilton Division of Endocrinology and Metabolism, Department of Obstetrics, University of Texas at Austin Marine Science Institute, Department of Medicine, Stanford University, Stanford, California 94305, USA

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Y Pang Division of Endocrinology and Metabolism, Department of Obstetrics, University of Texas at Austin Marine Science Institute, Department of Medicine, Stanford University, Stanford, California 94305, USA

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M T Overgaard Division of Endocrinology and Metabolism, Department of Obstetrics, University of Texas at Austin Marine Science Institute, Department of Medicine, Stanford University, Stanford, California 94305, USA

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S Tulac Division of Endocrinology and Metabolism, Department of Obstetrics, University of Texas at Austin Marine Science Institute, Department of Medicine, Stanford University, Stanford, California 94305, USA

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J Dong Division of Endocrinology and Metabolism, Department of Obstetrics, University of Texas at Austin Marine Science Institute, Department of Medicine, Stanford University, Stanford, California 94305, USA

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P Thomas Division of Endocrinology and Metabolism, Department of Obstetrics, University of Texas at Austin Marine Science Institute, Department of Medicine, Stanford University, Stanford, California 94305, USA

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L C Giudice Division of Endocrinology and Metabolism, Department of Obstetrics, University of Texas at Austin Marine Science Institute, Department of Medicine, Stanford University, Stanford, California 94305, USA

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, mPRα, mPRβ, and mPRγ expression were amplified cDNAs synthesized from RNA from decidualized human endometrial stromal cells (NIH SCCPRR Tissue Bank at the Stanford University), human testes (BD Biosciences Clontech), human brain (BD Biosciences Clontech

Article Type:
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DOI:
https://doi.org/10.1677/JOE-07-0317
Volume/Issue:
Volume 196: Issue 1
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Junny Chan
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Elizabeth H Rabbitt
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Barbara A Innes
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Judith N Bulmer
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Paul M Stewart
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Mark D Kilby
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Martin Hewison
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decidualized stromal cells, leucocytes (Fig. 4A ), and extravillous trophoblast. In third trimester superficial decidua basal is attached to the placenta and there was immunopositivity for active caspase-3 in decidualized stromal cells and extravillous

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-07-0289
Volume/Issue:
Volume 195: Issue 1
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Jin-Wen Xu Section of Pathophysiology, Department of Health and Bio-pharmaceutical Sciences, Department of Biotics, Department of Surgery, Hanabusa Women's Clinic, Departments of Obstetrics and Gynecology, Institute for World Health Development, Department of Pharmacy

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Naomi Yasui Section of Pathophysiology, Department of Health and Bio-pharmaceutical Sciences, Department of Biotics, Department of Surgery, Hanabusa Women's Clinic, Departments of Obstetrics and Gynecology, Institute for World Health Development, Department of Pharmacy

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Katsumi Ikeda Section of Pathophysiology, Department of Health and Bio-pharmaceutical Sciences, Department of Biotics, Department of Surgery, Hanabusa Women's Clinic, Departments of Obstetrics and Gynecology, Institute for World Health Development, Department of Pharmacy

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Wei-Jun Pan Section of Pathophysiology, Department of Health and Bio-pharmaceutical Sciences, Department of Biotics, Department of Surgery, Hanabusa Women's Clinic, Departments of Obstetrics and Gynecology, Institute for World Health Development, Department of Pharmacy
Section of Pathophysiology, Department of Health and Bio-pharmaceutical Sciences, Department of Biotics, Department of Surgery, Hanabusa Women's Clinic, Departments of Obstetrics and Gynecology, Institute for World Health Development, Department of Pharmacy

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June Watanabe Section of Pathophysiology, Department of Health and Bio-pharmaceutical Sciences, Department of Biotics, Department of Surgery, Hanabusa Women's Clinic, Departments of Obstetrics and Gynecology, Institute for World Health Development, Department of Pharmacy

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Masahide Shiotani Section of Pathophysiology, Department of Health and Bio-pharmaceutical Sciences, Department of Biotics, Department of Surgery, Hanabusa Women's Clinic, Departments of Obstetrics and Gynecology, Institute for World Health Development, Department of Pharmacy

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Atsushi Yanaihara Section of Pathophysiology, Department of Health and Bio-pharmaceutical Sciences, Department of Biotics, Department of Surgery, Hanabusa Women's Clinic, Departments of Obstetrics and Gynecology, Institute for World Health Development, Department of Pharmacy

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Tomohiro Miki Section of Pathophysiology, Department of Health and Bio-pharmaceutical Sciences, Department of Biotics, Department of Surgery, Hanabusa Women's Clinic, Departments of Obstetrics and Gynecology, Institute for World Health Development, Department of Pharmacy

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Yukio Yamori Section of Pathophysiology, Department of Health and Bio-pharmaceutical Sciences, Department of Biotics, Department of Surgery, Hanabusa Women's Clinic, Departments of Obstetrics and Gynecology, Institute for World Health Development, Department of Pharmacy

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( Kimber 2005 ). Transforming growth factor β (TGF-β) promotes the decidualization of endometrial stroma and is important in the maternal support of embryo development in the human endometrium ( Tamada et al . 1990 , Das et al . 1992 ). Glycodelin is a

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-07-0416
Volume/Issue:
Volume 196: Issue 2
Free access
M S Fernandes Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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V Pierron Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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D Michalovich Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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S Astle Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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S Thornton Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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H Peltoketo Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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E W-F Lam Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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B Gellersen Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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I Huhtaniemi Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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J Allen Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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J J Brosens Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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the endometrium that initially define a limited period of uterine receptivity (implantation window) and subsequently control differentiation of the stromal compartment (decidualization) ( Brosens et al. 1999 , Gellersen & Brosens 2003 ). This

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06242
Volume/Issue:
Volume 187: Issue 1
Free access
Ioannis Simitsidellis Centre for Inflammation Research, The University of Edinburgh, Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK

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Arantza Esnal-Zuffiaure Centre for Inflammation Research, The University of Edinburgh, Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK

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Olympia Kelepouri Centre for Inflammation Research, The University of Edinburgh, Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK

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Elisabeth O’Flaherty Centre for Inflammation Research, The University of Edinburgh, Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK

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Douglas A Gibson Centre for Inflammation Research, The University of Edinburgh, Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK

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Philippa T K Saunders Centre for Inflammation Research, The University of Edinburgh, Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK

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Endometrial glands are essential for blastocyst implantation and decidualization in the mouse uterus . Biology of Reproduction 88 93 . ( https://doi.org/10.1095/biolreprod.113.107631 ) 23407384 Franco HL Dai D Lee KY Rubel CA Roop D Boerboom

Article Type:
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DOI:
https://doi.org/10.1530/JOE-19-0153
Volume/Issue:
Volume 242: Issue 3
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Sourav Kundu
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Kousik Pramanick
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Sudipta Paul
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Arun Bandyopadhyay Endocrinology Laboratory, Indian Institute of Chemical Biology, Department of Zoology, University of Kalyani, Kalyani 741235, West Bengal, India

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Dilip Mukherjee
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directly affect in vitro decidualization of human endometrial stromal cells ( Kasahara et al . 2001 ). It has also been shown that although LH and FSH evoke a growth response in different endometrial cell lines, their stimulation does not appear to be

Article Type:
Research Article
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https://doi.org/10.1530/JOE-11-0486
Volume/Issue:
Volume 215: Issue 1
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Eric W-F Lam Cancer Research-UK Laboratories, Institute of Reproductive and Developmental Biology, Division of Cancer and

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Kunal Shah Cancer Research-UK Laboratories, Institute of Reproductive and Developmental Biology, Division of Cancer and

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Jan J Brosens Cancer Research-UK Laboratories, Institute of Reproductive and Developmental Biology, Division of Cancer and

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.1147535 . Christian M Mak I White JO Brosens JJ 2002a Mechanisms of decidualization . Reproductive BioMedicine Online 4 ( Supplement 3 ) 24 – 30 . Christian M Pohnke Y Kempf R Gellersen B Brosens JJ 2002b Functional

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https://doi.org/10.1530/JOE-10-0480
Volume/Issue:
Volume 212: Issue 1
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Yaxiong Huang Department of Reproductive Medicine center, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, PR China
Hubei Clinical Research Center for Prenatal Diagnosis and Birth Health, Wuhan Hubei Province, PR China
Wuhan Clinical Research Center for Reproductive Science and Birth Health, Wuhan Hubei Province, PR China
Department of Gynaecology and Obstetrics, Sinopharm Dongfeng Hospital, Hubei University of Medicine, Shiyan, Hubei Province, PR China

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Zihan Wang Department of Reproductive Medicine center, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, PR China
Hubei Clinical Research Center for Prenatal Diagnosis and Birth Health, Wuhan Hubei Province, PR China
Wuhan Clinical Research Center for Reproductive Science and Birth Health, Wuhan Hubei Province, PR China

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Bin Li Department of Gynaecology and Obstetrics, Sinopharm Dongfeng Hospital, Hubei University of Medicine, Shiyan, Hubei Province, PR China

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Lina Ke Department of Gynaecology and Obstetrics, Sinopharm Dongfeng Hospital, Hubei University of Medicine, Shiyan, Hubei Province, PR China

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Yao Xiong Department of Reproductive Medicine center, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, PR China
Hubei Clinical Research Center for Prenatal Diagnosis and Birth Health, Wuhan Hubei Province, PR China
Wuhan Clinical Research Center for Reproductive Science and Birth Health, Wuhan Hubei Province, PR China

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Yuanzhen Zhang Department of Reproductive Medicine center, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, PR China
Hubei Clinical Research Center for Prenatal Diagnosis and Birth Health, Wuhan Hubei Province, PR China
Wuhan Clinical Research Center for Reproductive Science and Birth Health, Wuhan Hubei Province, PR China

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orchestrating endometrial receptivity during embryo implantation. Studies reveal that specific KLF family members, including KLF12, exert a negative regulatory influence on human endometrial receptivity. Notably, KLF12 inhibits the decidualization of human

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-23-0319
Volume/Issue:
Volume 261: Issue 2
Open access