Search Results

You are looking at 51 - 60 of 4,484 items for :

  • Refine by access: All content x
Clear All
Laura D Brown Department of Pediatrics (Neonatology), Perinatal Research Center, University of Colorado School of Medicine, Anschutz Medical Campus F441, 13243 East 23rd Avenue, Aurora, Colorado 80045, USA

Search for other papers by Laura D Brown in
Google Scholar
PubMed
Close

of birth, defined arbitrarily as birth weight <10% on standard pediatric growth curves ( Battaglia & Lubchenco 1967 ), can result from many causes, one of which is placental insufficiency ( Platz & Newman 2008 ). Placental insufficiency is defined as

Free access
V E MacRae Bone Biology Group, Division of Gene Function and Development, Roslin Institute, Roslin, Midlothian EH25 9PS, UK
Bone and Endocrine Research Group, Royal Hospital for Sick Children, Glasgow, UK

Search for other papers by V E MacRae in
Google Scholar
PubMed
Close
,
T Burdon Bone Biology Group, Division of Gene Function and Development, Roslin Institute, Roslin, Midlothian EH25 9PS, UK
Bone and Endocrine Research Group, Royal Hospital for Sick Children, Glasgow, UK

Search for other papers by T Burdon in
Google Scholar
PubMed
Close
,
S F Ahmed Bone Biology Group, Division of Gene Function and Development, Roslin Institute, Roslin, Midlothian EH25 9PS, UK
Bone and Endocrine Research Group, Royal Hospital for Sick Children, Glasgow, UK

Search for other papers by S F Ahmed in
Google Scholar
PubMed
Close
, and
C Farquharson Bone Biology Group, Division of Gene Function and Development, Roslin Institute, Roslin, Midlothian EH25 9PS, UK
Bone and Endocrine Research Group, Royal Hospital for Sick Children, Glasgow, UK

Search for other papers by C Farquharson in
Google Scholar
PubMed
Close

Introduction Chronic inflammatory diseases such as juvenile idiopathic arthritis and inflammatory bowel disease often lead to childhood growth retardation through a number of proposed mechanisms that includes nutritional deficiency

Free access
Motoi Sohmiya Department of Endocrinology, Metabolism and Hematological Oncology, Shimane University School of Medicine, Izumo 693-8501, Japan

Search for other papers by Motoi Sohmiya in
Google Scholar
PubMed
Close
and
Yuzuru Kato Department of Endocrinology, Metabolism and Hematological Oncology, Shimane University School of Medicine, Izumo 693-8501, Japan

Search for other papers by Yuzuru Kato in
Google Scholar
PubMed
Close

). Hypopituitarism is often accompanied by normochromic and normocytic anemia. Androgen and thyroid hormones are known to stimulate erythropoiesis ( Alexanian 1969 ). Growth hormone (GH) has a stimulatory effect on erythropoiesis ( Fisher et al. 1964 , Meineke

Free access
Pongpan Tanajak Cardiac Electrophysiology Research and Training Center, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine
Cardiac Electrophysiology Research and Training Center, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine

Search for other papers by Pongpan Tanajak in
Google Scholar
PubMed
Close
,
Siriporn C Chattipakorn Cardiac Electrophysiology Research and Training Center, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine
Cardiac Electrophysiology Research and Training Center, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine
Cardiac Electrophysiology Research and Training Center, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine

Search for other papers by Siriporn C Chattipakorn in
Google Scholar
PubMed
Close
, and
Nipon Chattipakorn Cardiac Electrophysiology Research and Training Center, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine
Cardiac Electrophysiology Research and Training Center, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine
Cardiac Electrophysiology Research and Training Center, Cardiac Electrophysiology Unit, Center of Excellence in Cardiac Electrophysiology Research, Department of Oral Biology and Diagnostic Sciences, Faculty of Medicine

Search for other papers by Nipon Chattipakorn in
Google Scholar
PubMed
Close

Introduction Fibroblast growth factors (FGFs) are polypeptide chains that have paracrine, autocrine or endocrine functions. The paracrine FGFs are further divided into five subfamilies, whereas the autocrine and endocrine FGFs are composed of one

Free access
Neele S Dellschaft Early Life Research Unit, INRA and University of Nantes, School of Veterinary Medicine and Science, Institute of Health Sciences, Oniris, Department of Animal Science, Academic Division of Child Health, Obstetrics and Gynaecology, School of Medicine, Queen's Medical Centre, The University of Nottingham, Nottingham NG7 2UH, UK
Early Life Research Unit, INRA and University of Nantes, School of Veterinary Medicine and Science, Institute of Health Sciences, Oniris, Department of Animal Science, Academic Division of Child Health, Obstetrics and Gynaecology, School of Medicine, Queen's Medical Centre, The University of Nottingham, Nottingham NG7 2UH, UK

Search for other papers by Neele S Dellschaft in
Google Scholar
PubMed
Close
,
Marie-Cecile Alexandre-Gouabau Early Life Research Unit, INRA and University of Nantes, School of Veterinary Medicine and Science, Institute of Health Sciences, Oniris, Department of Animal Science, Academic Division of Child Health, Obstetrics and Gynaecology, School of Medicine, Queen's Medical Centre, The University of Nottingham, Nottingham NG7 2UH, UK

Search for other papers by Marie-Cecile Alexandre-Gouabau in
Google Scholar
PubMed
Close
,
David S Gardner Early Life Research Unit, INRA and University of Nantes, School of Veterinary Medicine and Science, Institute of Health Sciences, Oniris, Department of Animal Science, Academic Division of Child Health, Obstetrics and Gynaecology, School of Medicine, Queen's Medical Centre, The University of Nottingham, Nottingham NG7 2UH, UK

Search for other papers by David S Gardner in
Google Scholar
PubMed
Close
,
Jean-Philippe Antignac Early Life Research Unit, INRA and University of Nantes, School of Veterinary Medicine and Science, Institute of Health Sciences, Oniris, Department of Animal Science, Academic Division of Child Health, Obstetrics and Gynaecology, School of Medicine, Queen's Medical Centre, The University of Nottingham, Nottingham NG7 2UH, UK

Search for other papers by Jean-Philippe Antignac in
Google Scholar
PubMed
Close
,
Duane H Keisler Early Life Research Unit, INRA and University of Nantes, School of Veterinary Medicine and Science, Institute of Health Sciences, Oniris, Department of Animal Science, Academic Division of Child Health, Obstetrics and Gynaecology, School of Medicine, Queen's Medical Centre, The University of Nottingham, Nottingham NG7 2UH, UK

Search for other papers by Duane H Keisler in
Google Scholar
PubMed
Close
,
Helen Budge Early Life Research Unit, INRA and University of Nantes, School of Veterinary Medicine and Science, Institute of Health Sciences, Oniris, Department of Animal Science, Academic Division of Child Health, Obstetrics and Gynaecology, School of Medicine, Queen's Medical Centre, The University of Nottingham, Nottingham NG7 2UH, UK

Search for other papers by Helen Budge in
Google Scholar
PubMed
Close
,
Michael E Symonds Early Life Research Unit, INRA and University of Nantes, School of Veterinary Medicine and Science, Institute of Health Sciences, Oniris, Department of Animal Science, Academic Division of Child Health, Obstetrics and Gynaecology, School of Medicine, Queen's Medical Centre, The University of Nottingham, Nottingham NG7 2UH, UK

Search for other papers by Michael E Symonds in
Google Scholar
PubMed
Close
, and
Sylvain P Sebert Early Life Research Unit, INRA and University of Nantes, School of Veterinary Medicine and Science, Institute of Health Sciences, Oniris, Department of Animal Science, Academic Division of Child Health, Obstetrics and Gynaecology, School of Medicine, Queen's Medical Centre, The University of Nottingham, Nottingham NG7 2UH, UK
Early Life Research Unit, INRA and University of Nantes, School of Veterinary Medicine and Science, Institute of Health Sciences, Oniris, Department of Animal Science, Academic Division of Child Health, Obstetrics and Gynaecology, School of Medicine, Queen's Medical Centre, The University of Nottingham, Nottingham NG7 2UH, UK

Search for other papers by Sylvain P Sebert in
Google Scholar
PubMed
Close

, outcomes linked to mechanisms affecting the size at birth ( Barker 1997 , Roseboom et al . 2000 ). In large mammals, including sheep, pigs, and humans, chronic caloric restriction throughout late gestation results in intra-uterine growth retardation (IUGR

Free access
J T Smith School of Human Sciences, The University of Western Australia, Perth, Western Australia, Australia

Search for other papers by J T Smith in
Google Scholar
PubMed
Close
,
A Roseweir Academic Unit of Surgery, School of Medicine, University of Glasgow, Royal Infirmary, Glasgow, UK
Unit of Experimental Therapeutics, Institute of Cancer Sciences, University of Glasgow Glasgow, UK

Search for other papers by A Roseweir in
Google Scholar
PubMed
Close
,
M Millar Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK

Search for other papers by M Millar in
Google Scholar
PubMed
Close
,
I J Clarke Department of Physiology, Monash University, Clayton, Victoria, Australia

Search for other papers by I J Clarke in
Google Scholar
PubMed
Close
, and
R P Millar Centre for Neuroendocrinology, Department of Immunology and Physiology, University of Pretoria, Pretoria, South Africa
Institute for Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa

Search for other papers by R P Millar in
Google Scholar
PubMed
Close

physiological status to reproduction ( Pineda et al . 2010 a ). Growth hormone (GH) plays a role in normal reproductive function ( Hull & Harvey 2001 , 2002 ) and in metabolic regulation. A substantial number of studies have now reported effects of

Free access
Yao Wang Prince Henry's Institute of Medical Research, Department of Biochemistry, School of Paediatrics and Reproductive Health, Department of Obstetrics and Gynaecology, Department of Physiology, PO Box 5152, Clayton, Victoria 3168, Australia

Search for other papers by Yao Wang in
Google Scholar
PubMed
Close
,
Peter K Nicholls Prince Henry's Institute of Medical Research, Department of Biochemistry, School of Paediatrics and Reproductive Health, Department of Obstetrics and Gynaecology, Department of Physiology, PO Box 5152, Clayton, Victoria 3168, Australia
Prince Henry's Institute of Medical Research, Department of Biochemistry, School of Paediatrics and Reproductive Health, Department of Obstetrics and Gynaecology, Department of Physiology, PO Box 5152, Clayton, Victoria 3168, Australia

Search for other papers by Peter K Nicholls in
Google Scholar
PubMed
Close
,
Peter G Stanton Prince Henry's Institute of Medical Research, Department of Biochemistry, School of Paediatrics and Reproductive Health, Department of Obstetrics and Gynaecology, Department of Physiology, PO Box 5152, Clayton, Victoria 3168, Australia
Prince Henry's Institute of Medical Research, Department of Biochemistry, School of Paediatrics and Reproductive Health, Department of Obstetrics and Gynaecology, Department of Physiology, PO Box 5152, Clayton, Victoria 3168, Australia

Search for other papers by Peter G Stanton in
Google Scholar
PubMed
Close
,
Craig A Harrison Prince Henry's Institute of Medical Research, Department of Biochemistry, School of Paediatrics and Reproductive Health, Department of Obstetrics and Gynaecology, Department of Physiology, PO Box 5152, Clayton, Victoria 3168, Australia
Prince Henry's Institute of Medical Research, Department of Biochemistry, School of Paediatrics and Reproductive Health, Department of Obstetrics and Gynaecology, Department of Physiology, PO Box 5152, Clayton, Victoria 3168, Australia

Search for other papers by Craig A Harrison in
Google Scholar
PubMed
Close
,
Mai Sarraj Prince Henry's Institute of Medical Research, Department of Biochemistry, School of Paediatrics and Reproductive Health, Department of Obstetrics and Gynaecology, Department of Physiology, PO Box 5152, Clayton, Victoria 3168, Australia

Search for other papers by Mai Sarraj in
Google Scholar
PubMed
Close
,
Robert B Gilchrist Prince Henry's Institute of Medical Research, Department of Biochemistry, School of Paediatrics and Reproductive Health, Department of Obstetrics and Gynaecology, Department of Physiology, PO Box 5152, Clayton, Victoria 3168, Australia

Search for other papers by Robert B Gilchrist in
Google Scholar
PubMed
Close
,
Jock K Findlay Prince Henry's Institute of Medical Research, Department of Biochemistry, School of Paediatrics and Reproductive Health, Department of Obstetrics and Gynaecology, Department of Physiology, PO Box 5152, Clayton, Victoria 3168, Australia
Prince Henry's Institute of Medical Research, Department of Biochemistry, School of Paediatrics and Reproductive Health, Department of Obstetrics and Gynaecology, Department of Physiology, PO Box 5152, Clayton, Victoria 3168, Australia

Search for other papers by Jock K Findlay in
Google Scholar
PubMed
Close
, and
Paul G Farnworth Prince Henry's Institute of Medical Research, Department of Biochemistry, School of Paediatrics and Reproductive Health, Department of Obstetrics and Gynaecology, Department of Physiology, PO Box 5152, Clayton, Victoria 3168, Australia
Prince Henry's Institute of Medical Research, Department of Biochemistry, School of Paediatrics and Reproductive Health, Department of Obstetrics and Gynaecology, Department of Physiology, PO Box 5152, Clayton, Victoria 3168, Australia

Search for other papers by Paul G Farnworth in
Google Scholar
PubMed
Close

Introduction The transforming growth factor-β (TGF-β or TGFB), superfamily of growth and differentiation factors are dimeric proteins that display a wide range of context-dependent local actions within diverse tissues ( Massague 1998 , Chang et al

Free access
ANNE STOCKELL HARTREE
Search for other papers by ANNE STOCKELL HARTREE in
Google Scholar
PubMed
Close
,
NADA KOVAČIĆ
Search for other papers by NADA KOVAČIĆ in
Google Scholar
PubMed
Close
, and
MARJORIE THOMAS
Search for other papers by MARJORIE THOMAS in
Google Scholar
PubMed
Close

SUMMARY

Human growth hormone prepared by Raben's (1959) method was chromatographed on various ion exchangers and the resulting fractions were assayed for growth-promoting, luteotrophic and immunological activity. A critical quantitative study of the biological activities of the fractions showed that there were significant differences between their ratios of growth-promoting to luteotrophic potency. The luteotrophic activity of some of the preparations was slightly higher than that of the 2nd International Ovine Prolactin Standard.

Restricted access
María E Díaz
Search for other papers by María E Díaz in
Google Scholar
PubMed
Close
,
Johanna G Miquet
Search for other papers by Johanna G Miquet in
Google Scholar
PubMed
Close
,
Soledad P Rossi Departamento de Química Biológica, Instituto de Biología y Medicina Experimental, Facultad de Farmacia y Bioquímica, Instituto de Química y Fisicoquímica Biológicas (UBA‐CONICET), Universidad de Buenos Aires, Junín 956, 1113 Ciudad de Buenos Aires, Argentina

Search for other papers by Soledad P Rossi in
Google Scholar
PubMed
Close
,
Pablo E Irene
Search for other papers by Pablo E Irene in
Google Scholar
PubMed
Close
,
Ana I Sotelo
Search for other papers by Ana I Sotelo in
Google Scholar
PubMed
Close
,
Mónica B Frungieri Departamento de Química Biológica, Instituto de Biología y Medicina Experimental, Facultad de Farmacia y Bioquímica, Instituto de Química y Fisicoquímica Biológicas (UBA‐CONICET), Universidad de Buenos Aires, Junín 956, 1113 Ciudad de Buenos Aires, Argentina

Search for other papers by Mónica B Frungieri in
Google Scholar
PubMed
Close
,
Daniel Turyn
Search for other papers by Daniel Turyn in
Google Scholar
PubMed
Close
, and
Lorena González
Search for other papers by Lorena González in
Google Scholar
PubMed
Close

Introduction Growth hormone (GH) is a pituitary hormone that stimulates longitudinal bone growth; it induces diverse effects on cell growth and differentiation, and on the metabolism of proteins, lipids, and carbohydrates ( Herrington & Carter

Free access
A S Chagin Pediatric Endocrinology Unit, Department of Woman and Child Health, Karolinska Institute, Karolinska University Hospital, SE-171 76 Stockholm, Sweden
Department of Biochemistry and Molecular Dentistry, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan

Search for other papers by A S Chagin in
Google Scholar
PubMed
Close
,
D Chrysis Pediatric Endocrinology Unit, Department of Woman and Child Health, Karolinska Institute, Karolinska University Hospital, SE-171 76 Stockholm, Sweden
Department of Biochemistry and Molecular Dentistry, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan

Search for other papers by D Chrysis in
Google Scholar
PubMed
Close
,
M Takigawa Pediatric Endocrinology Unit, Department of Woman and Child Health, Karolinska Institute, Karolinska University Hospital, SE-171 76 Stockholm, Sweden
Department of Biochemistry and Molecular Dentistry, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan

Search for other papers by M Takigawa in
Google Scholar
PubMed
Close
,
E M Ritzen Pediatric Endocrinology Unit, Department of Woman and Child Health, Karolinska Institute, Karolinska University Hospital, SE-171 76 Stockholm, Sweden
Department of Biochemistry and Molecular Dentistry, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan

Search for other papers by E M Ritzen in
Google Scholar
PubMed
Close
, and
L Sävendahl Pediatric Endocrinology Unit, Department of Woman and Child Health, Karolinska Institute, Karolinska University Hospital, SE-171 76 Stockholm, Sweden
Department of Biochemistry and Molecular Dentistry, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan

Search for other papers by L Sävendahl in
Google Scholar
PubMed
Close

Introduction Longitudinal bone growth occurs at the growth plate, a thin layer of chondrocytes between the epiphysis and the metaphysis of long bones, through a process called endochondral ossification, in which cartilage is first

Free access