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Stephen P Ashcroft
Stephen P Ashcroft
School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK
MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, Clinical, Metabolic and Molecular Physiology, University of Nottingham, Royal Derby Hospital Centre, Derby, UK
Mitochondrial Metabolism and Ageing Laboratory, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
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MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, Clinical, Metabolic and Molecular Physiology, University of Nottingham, Royal Derby Hospital Centre, Derby, UK
Mitochondrial Metabolism and Ageing Laboratory, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
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Gareth Fletcher
Gareth Fletcher
Mitochondrial Metabolism and Ageing Laboratory, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
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Ashleigh M Philp
Ashleigh M Philp
Mitochondrial Metabolism and Ageing Laboratory, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
St Vincent’s Clinical School, UNSW Medicine, UNSW Sydney, New South Wales, Australia
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St Vincent’s Clinical School, UNSW Medicine, UNSW Sydney, New South Wales, Australia
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Carl Jenkinson
Carl Jenkinson
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
ANZAC Research Institute, University of Sydney, Sydney, New South Wales, Australia
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ANZAC Research Institute, University of Sydney, Sydney, New South Wales, Australia
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Shatarupa Das
Shatarupa Das
Centenary Institute, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
UTS Centenary Centre for Inflammation, University Technology Sydney, New South Wales, Australia
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UTS Centenary Centre for Inflammation, University Technology Sydney, New South Wales, Australia
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Philip M Hansbro
Philip M Hansbro
Centenary Institute, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
UTS Centenary Centre for Inflammation, University Technology Sydney, New South Wales, Australia
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UTS Centenary Centre for Inflammation, University Technology Sydney, New South Wales, Australia
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Philip J Atherton
Philip J Atherton
MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, Clinical, Metabolic and Molecular Physiology, University of Nottingham, Royal Derby Hospital Centre, Derby, UK
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Andrew Philp
Andrew Philp
Mitochondrial Metabolism and Ageing Laboratory, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
St Vincent’s Clinical School, UNSW Medicine, UNSW Sydney, New South Wales, Australia
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St Vincent’s Clinical School, UNSW Medicine, UNSW Sydney, New South Wales, Australia
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muscle atrophy in response to transient knockdown of the vitamin D receptor in vivo . Journal of Physiology 599 963 – 979 . ( https://doi.org/10.1113/JP280652 ) Beaudart C Buckinx F Rabenda V Gillain S Cavalier E Slomian J Petermans J
Guillermo García-Eguren
Guillermo García-Eguren
Group of Endocrine Disorders, IDIBAPS, Barcelona, Spain
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Oriol Giró
Oriol Giró
Group of Endocrine Disorders, IDIBAPS, Barcelona, Spain
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María del Mar Romero
María del Mar Romero
Department of Biochemistry and Molecular Biomedicine, Section of Nutrition, Faculty of Biology, University of Barcelona, Barcelona, Spain
Institute of Biomedicine, University of Barcelona, Barcelona, Spain
Centro de Investigación Biomédica en Red de Obesidad y Nutrición (CIBEROBN), Carlos III Health Institute, Madrid, Spain
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Institute of Biomedicine, University of Barcelona, Barcelona, Spain
Centro de Investigación Biomédica en Red de Obesidad y Nutrición (CIBEROBN), Carlos III Health Institute, Madrid, Spain
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Mar Grasa
Mar Grasa
Department of Biochemistry and Molecular Biomedicine, Section of Nutrition, Faculty of Biology, University of Barcelona, Barcelona, Spain
Institute of Biomedicine, University of Barcelona, Barcelona, Spain
Centro de Investigación Biomédica en Red de Obesidad y Nutrición (CIBEROBN), Carlos III Health Institute, Madrid, Spain
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Institute of Biomedicine, University of Barcelona, Barcelona, Spain
Centro de Investigación Biomédica en Red de Obesidad y Nutrición (CIBEROBN), Carlos III Health Institute, Madrid, Spain
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Felicia A Hanzu
Felicia A Hanzu
Group of Endocrine Disorders, IDIBAPS, Barcelona, Spain
Department of Endocrinology and Nutrition, Hospital Clinic of Barcelona, Barcelona, Spain
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Carlos III Health Institute, Madrid, Spain
Department of Medicine, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain
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Department of Endocrinology and Nutrition, Hospital Clinic of Barcelona, Barcelona, Spain
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Carlos III Health Institute, Madrid, Spain
Department of Medicine, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain
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.1530/eje.0.1490561 ) Schakman O Kalista S Barbé C Loumaye A Thissen JP 2013 Glucocorticoid-induced skeletal muscle atrophy . International Journal of Biochemistry and Cell Biology 45 . ( https://doi.org/10.1016/j.biocel.2013
Ioannis Simitsidellis
Ioannis Simitsidellis
Centre for Inflammation Research, The University of Edinburgh, Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK
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Arantza Esnal-Zuffiaure
Arantza Esnal-Zuffiaure
Centre for Inflammation Research, The University of Edinburgh, Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK
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Olympia Kelepouri
Olympia Kelepouri
Centre for Inflammation Research, The University of Edinburgh, Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK
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Elisabeth O’Flaherty
Elisabeth O’Flaherty
Centre for Inflammation Research, The University of Edinburgh, Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK
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Douglas A Gibson
Douglas A Gibson
Centre for Inflammation Research, The University of Edinburgh, Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK
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Philippa T K Saunders
Philippa T K Saunders
Centre for Inflammation Research, The University of Edinburgh, Queen’s Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK
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. ( https://doi.org/10.1055/s-0034-1376354 ) 24959816 Timmer LT Hoogaars WMH Jaspers RT 2018 The role of IGF-1 signaling in skeletal muscle atrophy . Advances in Experimental Medicine and Biology 1088 . ( https://doi.org/10
Baiyang You
Baiyang You
Cardiac Rehabilitation Center, Department of Rehabilitation, Xiangya Hospital of Central South University, Changsha, Hunan, China
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Yaoshan Dun
Yaoshan Dun
Cardiac Rehabilitation Center, Department of Rehabilitation, Xiangya Hospital of Central South University, Changsha, Hunan, China
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Wenliang Zhang
Wenliang Zhang
Cardiac Rehabilitation Center, Department of Rehabilitation, Xiangya Hospital of Central South University, Changsha, Hunan, China
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Lingjun Jiang
Lingjun Jiang
Cardiac Rehabilitation Center, Department of Rehabilitation, Xiangya Hospital of Central South University, Changsha, Hunan, China
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Hui Li
Hui Li
Cardiac Rehabilitation Center, Department of Rehabilitation, Xiangya Hospital of Central South University, Changsha, Hunan, China
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Murong Xie
Murong Xie
Cardiac Rehabilitation Center, Department of Rehabilitation, Xiangya Hospital of Central South University, Changsha, Hunan, China
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Yuan Liu
Yuan Liu
Cardiac Rehabilitation Center, Department of Rehabilitation, Xiangya Hospital of Central South University, Changsha, Hunan, China
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Suixin Liu
Suixin Liu
Cardiac Rehabilitation Center, Department of Rehabilitation, Xiangya Hospital of Central South University, Changsha, Hunan, China
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cells . Cellular Signalling 1099 – 1104 . ( https://doi.org/10.1016/j.cellsig.2016.05.007 ) Wang D Sun H Song G Yang Y Zou X Han P Li S 2018 Resveratrol improves muscle atrophy by modulating mitochondrial quality control in STZ
Liselotte Fransson
Liselotte Fransson
Department of Clinical Science and Education, Division of Drug Research, Center of Medical Image Science and Visualization, Department of Biochemistry and Molecular Biology, Södersjukhuset, Karolinska Institutet, SE-118 83 Stockholm, Sweden
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Stephanie Franzén
Stephanie Franzén
Department of Clinical Science and Education, Division of Drug Research, Center of Medical Image Science and Visualization, Department of Biochemistry and Molecular Biology, Södersjukhuset, Karolinska Institutet, SE-118 83 Stockholm, Sweden
Department of Clinical Science and Education, Division of Drug Research, Center of Medical Image Science and Visualization, Department of Biochemistry and Molecular Biology, Södersjukhuset, Karolinska Institutet, SE-118 83 Stockholm, Sweden
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Department of Clinical Science and Education, Division of Drug Research, Center of Medical Image Science and Visualization, Department of Biochemistry and Molecular Biology, Södersjukhuset, Karolinska Institutet, SE-118 83 Stockholm, Sweden
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Victoria Rosengren
Victoria Rosengren
Department of Clinical Science and Education, Division of Drug Research, Center of Medical Image Science and Visualization, Department of Biochemistry and Molecular Biology, Södersjukhuset, Karolinska Institutet, SE-118 83 Stockholm, Sweden
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Petra Wolbert
Petra Wolbert
Department of Clinical Science and Education, Division of Drug Research, Center of Medical Image Science and Visualization, Department of Biochemistry and Molecular Biology, Södersjukhuset, Karolinska Institutet, SE-118 83 Stockholm, Sweden
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Åke Sjöholm
Åke Sjöholm
Department of Clinical Science and Education, Division of Drug Research, Center of Medical Image Science and Visualization, Department of Biochemistry and Molecular Biology, Södersjukhuset, Karolinska Institutet, SE-118 83 Stockholm, Sweden
Department of Clinical Science and Education, Division of Drug Research, Center of Medical Image Science and Visualization, Department of Biochemistry and Molecular Biology, Södersjukhuset, Karolinska Institutet, SE-118 83 Stockholm, Sweden
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Department of Clinical Science and Education, Division of Drug Research, Center of Medical Image Science and Visualization, Department of Biochemistry and Molecular Biology, Södersjukhuset, Karolinska Institutet, SE-118 83 Stockholm, Sweden
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Henrik Ortsäter
Henrik Ortsäter
Department of Clinical Science and Education, Division of Drug Research, Center of Medical Image Science and Visualization, Department of Biochemistry and Molecular Biology, Södersjukhuset, Karolinska Institutet, SE-118 83 Stockholm, Sweden
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Hypertension Reports 6 493 – 499 . ( doi:10.1007/s11906-004-0046-0 ) Barel M Perez OA Giozzet VA Rafacho A Bosqueiro JR do Amaral SL 2010 Exercise training prevents hyperinsulinemia, muscular glycogen loss and muscle atrophy induced by
Lucía Pronsato
Lucía Pronsato
Departamento de Biología, Bioquímica y Farmacia, Universidad Nacional del Sur, San Juan 670, Bahía Blanca 8000, Argentina
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Ricardo Boland
Ricardo Boland
Departamento de Biología, Bioquímica y Farmacia, Universidad Nacional del Sur, San Juan 670, Bahía Blanca 8000, Argentina
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Lorena Milanesi
Lorena Milanesi
Departamento de Biología, Bioquímica y Farmacia, Universidad Nacional del Sur, San Juan 670, Bahía Blanca 8000, Argentina
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.1152/ajpregu.00458.2001 . Dupont-Versteegden EE 2005 Apoptosis in muscle atrophy: relevance to sarcopenia . Experimental Gerontology 40 473 – 481 . doi:10.1016/j.exger.2005.04.003 . Erkkilä K Henriksén K Hirvonen V Rannikko S Salo J
Edward T Wargent
Edward T Wargent
Clore Laboratory, Obesity Biology Unit, University of Buckingham, Hunter Street, Buckingham MK18 1EG, UK
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Jacqueline F O'Dowd
Jacqueline F O'Dowd
Clore Laboratory, Obesity Biology Unit, University of Buckingham, Hunter Street, Buckingham MK18 1EG, UK
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Mohamed S Zaibi
Mohamed S Zaibi
Clore Laboratory, Obesity Biology Unit, University of Buckingham, Hunter Street, Buckingham MK18 1EG, UK
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Dan Gao
Dan Gao
Clore Laboratory, Obesity Biology Unit, University of Buckingham, Hunter Street, Buckingham MK18 1EG, UK
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Chen Bing
Chen Bing
Clore Laboratory, Obesity Biology Unit, University of Buckingham, Hunter Street, Buckingham MK18 1EG, UK
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Paul Trayhurn
Paul Trayhurn
Clore Laboratory, Obesity Biology Unit, University of Buckingham, Hunter Street, Buckingham MK18 1EG, UK
Clore Laboratory, Obesity Biology Unit, University of Buckingham, Hunter Street, Buckingham MK18 1EG, UK
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Clore Laboratory, Obesity Biology Unit, University of Buckingham, Hunter Street, Buckingham MK18 1EG, UK
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Michael A Cawthorne
Michael A Cawthorne
Clore Laboratory, Obesity Biology Unit, University of Buckingham, Hunter Street, Buckingham MK18 1EG, UK
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Jonathan R S Arch
Jonathan R S Arch
Clore Laboratory, Obesity Biology Unit, University of Buckingham, Hunter Street, Buckingham MK18 1EG, UK
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Claire J Stocker
Claire J Stocker
Clore Laboratory, Obesity Biology Unit, University of Buckingham, Hunter Street, Buckingham MK18 1EG, UK
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Tisdale MJ 2010a Antidiabetic properties of zinc-α 2 -glycoprotein in ob/ob mice . Endocrinology 151 948 – 957 . ( doi:10.1210/en.2009-0827 ) Russell ST Tisdale MJ 2010b Mechanism of attenuation of skeletal muscle atrophy by zinc-α 2
Melissa F Jackson
Melissa F Jackson
School of Molecular Biosciences, Veterinary Microbiology and Pathology, Animal Sciences, Departments of
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Dung Luong
Dung Luong
School of Molecular Biosciences, Veterinary Microbiology and Pathology, Animal Sciences, Departments of
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Dor Dor Vang
Dor Dor Vang
School of Molecular Biosciences, Veterinary Microbiology and Pathology, Animal Sciences, Departments of
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Dilip K Garikipati
Dilip K Garikipati
School of Molecular Biosciences, Veterinary Microbiology and Pathology, Animal Sciences, Departments of
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James B Stanton
James B Stanton
School of Molecular Biosciences, Veterinary Microbiology and Pathology, Animal Sciences, Departments of
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O Lynne Nelson
O Lynne Nelson
School of Molecular Biosciences, Veterinary Microbiology and Pathology, Animal Sciences, Departments of
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Buel D Rodgers
Buel D Rodgers
School of Molecular Biosciences, Veterinary Microbiology and Pathology, Animal Sciences, Departments of
School of Molecular Biosciences, Veterinary Microbiology and Pathology, Animal Sciences, Departments of
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School of Molecular Biosciences, Veterinary Microbiology and Pathology, Animal Sciences, Departments of
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0736-0266(03)00105-0 . Heineke J Auger-Messier M Xu J Sargent M York A Welle S Molkentin JD 2010 Genetic deletion of myostatin from the heart prevents skeletal muscle atrophy in heart failure . Circulation 121 419 – 425 . doi:10
Wenjun Deng
Wenjun Deng
Key Laboratory of Bio-resources and Eco-environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, PR China
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Mingyu Xu
Mingyu Xu
Key Laboratory of Bio-resources and Eco-environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, PR China
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Rui Dong
Rui Dong
Key Laboratory of Bio-resources and Eco-environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, PR China
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Yisha Yan
Yisha Yan
Key Laboratory of Bio-resources and Eco-environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, PR China
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Quan Jiang
Quan Jiang
Key Laboratory of Bio-resources and Eco-environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, PR China
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. However, this contrasts with studies in mice showing that irisin promotes hypertrophy and counteracts muscle atrophy ( Reza et al. 2017 ), which may be attributed to species-specific physiological differences. It is important to note that irisin has been
Ferran Jardí
Ferran Jardí
Clinical and Experimental Endocrinology, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Leuven, Belgium
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Michaël R Laurent
Michaël R Laurent
Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
Gerontology and Geriatrics, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Leuven, Belgium
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Gerontology and Geriatrics, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Leuven, Belgium
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Vanessa Dubois
Vanessa Dubois
Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
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Nari Kim
Nari Kim
Clinical and Experimental Endocrinology, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Leuven, Belgium
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Rougin Khalil
Rougin Khalil
Clinical and Experimental Endocrinology, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Leuven, Belgium
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Brigitte Decallonne
Brigitte Decallonne
Clinical and Experimental Endocrinology, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Leuven, Belgium
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Dirk Vanderschueren
Dirk Vanderschueren
Clinical and Experimental Endocrinology, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Leuven, Belgium
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Frank Claessens
Frank Claessens
Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
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skeletal muscle atrophy and enhances resistance to fatigue in orchidectomized male mice . American Journal of Physiology: Endocrinology and Metabolism 291 E506 – E516 . ( https://doi.org/10.1152/ajpendo.00058.2006 ) 10.1152/ajpendo.00058.2006) Ayaz O
