Search Results

You are looking at 51 - 60 of 1,488 items for :

  • "programming" x
  • Refine by access: All content x
Clear All
PJ Morgan
Search for other papers by PJ Morgan in
Google Scholar
PubMed
Close
,
AW Ross
Search for other papers by AW Ross in
Google Scholar
PubMed
Close
,
JG Mercer
Search for other papers by JG Mercer in
Google Scholar
PubMed
Close
, and
P Barrett
Search for other papers by P Barrett in
Google Scholar
PubMed
Close

The photoperiodic mammal undergoes quite remarkable changes in physiology as part of its natural adaptations to seasonal fluctuations in the environment. Changes in energy balance and body weight are among these adaptations. In some seasonal mammals, such as the Siberian hamster (Phodopus sungorus), these changes in body weight have been explored in detail, and there is evidence for tightly controlled systems of energy balance that are coordinated by photoperiod acting via the temporal pattern of melatonin secretion from the pineal gland. The pathways and systems involved appear to be quite distinct from the hypothalamic pathways identified to regulate energy balance in studies of both mice and rats thus far. Instead it appears that in the Siberian hamster a tightly regulated system under the control of photoperiod is able to reset the tone of the systems involved in energy balance regulation. Understanding how photoperiod and melatonin act within the hypothalamus to regulate energy balance offers potentially fundamental and important new insights into the control of energy balance. This review describes the current state of our knowledge.

Free access
Aijun Zhang Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA

Search for other papers by Aijun Zhang in
Google Scholar
PubMed
Close
,
Douglas H Sieglaff Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA

Search for other papers by Douglas H Sieglaff in
Google Scholar
PubMed
Close
,
Jean Philippe York Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA

Search for other papers by Jean Philippe York in
Google Scholar
PubMed
Close
,
Ji Ho Suh Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA

Search for other papers by Ji Ho Suh in
Google Scholar
PubMed
Close
,
Stephen D Ayers Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA

Search for other papers by Stephen D Ayers in
Google Scholar
PubMed
Close
,
Glenn E Winnier Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA

Search for other papers by Glenn E Winnier in
Google Scholar
PubMed
Close
,
Alexei Kharitonenkov Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA

Search for other papers by Alexei Kharitonenkov in
Google Scholar
PubMed
Close
,
Christopher Pin Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA
Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA

Search for other papers by Christopher Pin in
Google Scholar
PubMed
Close
,
Pumin Zhang Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA

Search for other papers by Pumin Zhang in
Google Scholar
PubMed
Close
,
Paul Webb Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA

Search for other papers by Paul Webb in
Google Scholar
PubMed
Close
, and
Xuefeng Xia Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA
Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA

Search for other papers by Xuefeng Xia in
Google Scholar
PubMed
Close

general. As FGF21 acts in an autocrine/paracrine fashion to regulate hepatic target genes involved in metabolic responses ( Inagaki et al . 2007 ), we also tested the hypothesis that T 3 -dependent regulation of hepatic gene expression programs would

Free access
Márta Szaszák
Search for other papers by Márta Szaszák in
Google Scholar
PubMed
Close
,
Hung-Dar Chen
Search for other papers by Hung-Dar Chen in
Google Scholar
PubMed
Close
,
Hao-Chia Chen
Search for other papers by Hao-Chia Chen in
Google Scholar
PubMed
Close
,
Albert Baukal
Search for other papers by Albert Baukal in
Google Scholar
PubMed
Close
,
László Hunyady Section on Hormonal Regulation, Department of Physiology, Endocrinology and Reproduction Research Branch, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892-4510, USA

Search for other papers by László Hunyady in
Google Scholar
PubMed
Close
, and
Kevin J Catt
Search for other papers by Kevin J Catt in
Google Scholar
PubMed
Close

Intramural Research Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development. Acknowledgements We thank Tamas Balla and Balazs Mihalik for their valuable discussions. Microscopy imaging was performed at the Microscopy

Free access
Leila Arbabi Neuroscience Program, Monash Biomedicine Discovery Institute and Department of Physiology, Monash University, Melbourne, Victoria, Australia

Search for other papers by Leila Arbabi in
Google Scholar
PubMed
Close
,
Qun Li Neuroscience Program, Monash Biomedicine Discovery Institute and Department of Physiology, Monash University, Melbourne, Victoria, Australia

Search for other papers by Qun Li in
Google Scholar
PubMed
Close
,
Belinda A Henry Metabolism, Diabetes and Obesity Program, Monash Biomedicine Discovery Institute and Department of Physiology, Monash University, Melbourne, Victoria, Australia

Search for other papers by Belinda A Henry in
Google Scholar
PubMed
Close
, and
Iain J Clarke Neuroscience Program, Monash Biomedicine Discovery Institute and Department of Physiology, Monash University, Melbourne, Victoria, Australia

Search for other papers by Iain J Clarke in
Google Scholar
PubMed
Close

hypothalamic neuronal cell line . Journal of Clinical Investigation 101 1334– 1341 . ( https://doi.org/10.1172/JCI610 ) Burger HG Lee VW Rennie GC 1972 A generalized computer program for the treatment of data front competitive protein

Restricted access
Norihiko Kato Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 3-10 Kanda-Surugadai 2-Chome, Chiyoda-ku Tokyo, Tokyo, Japan
Department of Cytokine Biology, The Forsyth Institute, Boston, Massachusetts, USA
Department of Cell Biology and Neuroscience, Rutgers University, Rutgers, New Jersey, USA
Department of Orthopedics, School of Medicine, Juntendo University, Tokyo, Japan
21st Century Center of Excellence (COE) Program for Frontier Research on Molecular Destruction and Reconstruction of Tooth and Bone, Tokyo, Japan
JSPS Core to Core Program, Japan
Hard Tissue Genome Research Center, Tokyo Medical and Dental University, Tokyo, Japan

Search for other papers by Norihiko Kato in
Google Scholar
PubMed
Close
,
Keiichiro Kitahara Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 3-10 Kanda-Surugadai 2-Chome, Chiyoda-ku Tokyo, Tokyo, Japan
Department of Cytokine Biology, The Forsyth Institute, Boston, Massachusetts, USA
Department of Cell Biology and Neuroscience, Rutgers University, Rutgers, New Jersey, USA
Department of Orthopedics, School of Medicine, Juntendo University, Tokyo, Japan
21st Century Center of Excellence (COE) Program for Frontier Research on Molecular Destruction and Reconstruction of Tooth and Bone, Tokyo, Japan
JSPS Core to Core Program, Japan
Hard Tissue Genome Research Center, Tokyo Medical and Dental University, Tokyo, Japan

Search for other papers by Keiichiro Kitahara in
Google Scholar
PubMed
Close
,
Susan R Rittling Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 3-10 Kanda-Surugadai 2-Chome, Chiyoda-ku Tokyo, Tokyo, Japan
Department of Cytokine Biology, The Forsyth Institute, Boston, Massachusetts, USA
Department of Cell Biology and Neuroscience, Rutgers University, Rutgers, New Jersey, USA
Department of Orthopedics, School of Medicine, Juntendo University, Tokyo, Japan
21st Century Center of Excellence (COE) Program for Frontier Research on Molecular Destruction and Reconstruction of Tooth and Bone, Tokyo, Japan
JSPS Core to Core Program, Japan
Hard Tissue Genome Research Center, Tokyo Medical and Dental University, Tokyo, Japan

Search for other papers by Susan R Rittling in
Google Scholar
PubMed
Close
,
Kazuhisa Nakashima Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 3-10 Kanda-Surugadai 2-Chome, Chiyoda-ku Tokyo, Tokyo, Japan
Department of Cytokine Biology, The Forsyth Institute, Boston, Massachusetts, USA
Department of Cell Biology and Neuroscience, Rutgers University, Rutgers, New Jersey, USA
Department of Orthopedics, School of Medicine, Juntendo University, Tokyo, Japan
21st Century Center of Excellence (COE) Program for Frontier Research on Molecular Destruction and Reconstruction of Tooth and Bone, Tokyo, Japan
JSPS Core to Core Program, Japan
Hard Tissue Genome Research Center, Tokyo Medical and Dental University, Tokyo, Japan

Search for other papers by Kazuhisa Nakashima in
Google Scholar
PubMed
Close
,
David T Denhardt Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 3-10 Kanda-Surugadai 2-Chome, Chiyoda-ku Tokyo, Tokyo, Japan
Department of Cytokine Biology, The Forsyth Institute, Boston, Massachusetts, USA
Department of Cell Biology and Neuroscience, Rutgers University, Rutgers, New Jersey, USA
Department of Orthopedics, School of Medicine, Juntendo University, Tokyo, Japan
21st Century Center of Excellence (COE) Program for Frontier Research on Molecular Destruction and Reconstruction of Tooth and Bone, Tokyo, Japan
JSPS Core to Core Program, Japan
Hard Tissue Genome Research Center, Tokyo Medical and Dental University, Tokyo, Japan

Search for other papers by David T Denhardt in
Google Scholar
PubMed
Close
,
Hisashi Kurosawa Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 3-10 Kanda-Surugadai 2-Chome, Chiyoda-ku Tokyo, Tokyo, Japan
Department of Cytokine Biology, The Forsyth Institute, Boston, Massachusetts, USA
Department of Cell Biology and Neuroscience, Rutgers University, Rutgers, New Jersey, USA
Department of Orthopedics, School of Medicine, Juntendo University, Tokyo, Japan
21st Century Center of Excellence (COE) Program for Frontier Research on Molecular Destruction and Reconstruction of Tooth and Bone, Tokyo, Japan
JSPS Core to Core Program, Japan
Hard Tissue Genome Research Center, Tokyo Medical and Dental University, Tokyo, Japan

Search for other papers by Hisashi Kurosawa in
Google Scholar
PubMed
Close
,
Yoichi Ezura Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 3-10 Kanda-Surugadai 2-Chome, Chiyoda-ku Tokyo, Tokyo, Japan
Department of Cytokine Biology, The Forsyth Institute, Boston, Massachusetts, USA
Department of Cell Biology and Neuroscience, Rutgers University, Rutgers, New Jersey, USA
Department of Orthopedics, School of Medicine, Juntendo University, Tokyo, Japan
21st Century Center of Excellence (COE) Program for Frontier Research on Molecular Destruction and Reconstruction of Tooth and Bone, Tokyo, Japan
JSPS Core to Core Program, Japan
Hard Tissue Genome Research Center, Tokyo Medical and Dental University, Tokyo, Japan

Search for other papers by Yoichi Ezura in
Google Scholar
PubMed
Close
, and
Masaki Noda Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 3-10 Kanda-Surugadai 2-Chome, Chiyoda-ku Tokyo, Tokyo, Japan
Department of Cytokine Biology, The Forsyth Institute, Boston, Massachusetts, USA
Department of Cell Biology and Neuroscience, Rutgers University, Rutgers, New Jersey, USA
Department of Orthopedics, School of Medicine, Juntendo University, Tokyo, Japan
21st Century Center of Excellence (COE) Program for Frontier Research on Molecular Destruction and Reconstruction of Tooth and Bone, Tokyo, Japan
JSPS Core to Core Program, Japan
Hard Tissue Genome Research Center, Tokyo Medical and Dental University, Tokyo, Japan

Search for other papers by Masaki Noda in
Google Scholar
PubMed
Close

Program, Molecular Destruction and Reconstitution of Tooth and Bone, 1701200821st Century COE Program, Molecular Destruction and Reconstitution of Tooth and Bone, 170118109011, 18659438, 18123456) and grants from the Japan Space Forum, NASDA, and the Japan

Free access
Jordan E Hamden Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada
Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada

Search for other papers by Jordan E Hamden in
Google Scholar
PubMed
Close
,
Melody Salehzadeh Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada
Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada

Search for other papers by Melody Salehzadeh in
Google Scholar
PubMed
Close
,
Katherine M Gray Department of Psychology, University of British Columbia, Vancouver, British Columbia, Canada
Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

Search for other papers by Katherine M Gray in
Google Scholar
PubMed
Close
,
Brandon J Forys Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada
Department of Psychology, University of British Columbia, Vancouver, British Columbia, Canada

Search for other papers by Brandon J Forys in
Google Scholar
PubMed
Close
, and
Kiran K Soma Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada
Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada
Department of Psychology, University of British Columbia, Vancouver, British Columbia, Canada
Graduate Program in Neuroscience, University of British Columbia, Vancouver, British Columbia, Canada

Search for other papers by Kiran K Soma in
Google Scholar
PubMed
Close

role for GCs in BCR function similar to their role in T cell receptor selection ( Cortez et al. 1996 , Cain et al. 2020 ). Endotoxin exposure and maternal separation during the SHRP have long-lasting programming effects on the immune system

Restricted access
Dipali Goyal School of Animal and Comparative Biomedical Sciences, College of Agriculture and Life Sciences, University of Arizona, Tucson, Arizona, USA

Search for other papers by Dipali Goyal in
Google Scholar
PubMed
Close
,
Sean W Limesand School of Animal and Comparative Biomedical Sciences, College of Agriculture and Life Sciences, University of Arizona, Tucson, Arizona, USA

Search for other papers by Sean W Limesand in
Google Scholar
PubMed
Close
, and
Ravi Goyal School of Animal and Comparative Biomedical Sciences, College of Agriculture and Life Sciences, University of Arizona, Tucson, Arizona, USA

Search for other papers by Ravi Goyal in
Google Scholar
PubMed
Close

, Jang et al. 2015 , Agarwal et al. 2018 , Ducsay et al. 2018 , Lecoutre et al. 2018 ). A factor that has received increasing attention, in this regard, is the idea of ‘developmental programming’ during fetal life, as a consequence of maternal

Free access
Hye-Jin Lee BK21 Graduate Program, Department of Biomedical Sciences, Korea University College of Medicine, Seoul, Republic of Korea
Department of Pharmacology, Korea University College of Medicine, Seoul, Republic of Korea

Search for other papers by Hye-Jin Lee in
Google Scholar
PubMed
Close
,
Haifei Shi Department of Biology, Miami University, Oxford, Ohio, USA

Search for other papers by Haifei Shi in
Google Scholar
PubMed
Close
,
Hella S Brönneke Max Planck Institute for Metabolism Research, Köln, Germany

Search for other papers by Hella S Brönneke in
Google Scholar
PubMed
Close
,
Bo-Yeong Jin BK21 Graduate Program, Department of Biomedical Sciences, Korea University College of Medicine, Seoul, Republic of Korea
Department of Pharmacology, Korea University College of Medicine, Seoul, Republic of Korea

Search for other papers by Bo-Yeong Jin in
Google Scholar
PubMed
Close
,
Sang-Hyun Choi Department of Pharmacology, Korea University College of Medicine, Seoul, Republic of Korea

Search for other papers by Sang-Hyun Choi in
Google Scholar
PubMed
Close
,
Randy J Seeley Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA

Search for other papers by Randy J Seeley in
Google Scholar
PubMed
Close
, and
Dong-Hoon Kim BK21 Graduate Program, Department of Biomedical Sciences, Korea University College of Medicine, Seoul, Republic of Korea
Department of Pharmacology, Korea University College of Medicine, Seoul, Republic of Korea

Search for other papers by Dong-Hoon Kim in
Google Scholar
PubMed
Close

was performed via customized injectors using the Pump 11 Harvard Apparatus. The analog signals were digitized using a data processing program. The average rate of tissue perfusion (arbitrary units) was recorded using LabScribe2 software (iWorx Systems

Restricted access
Patricia Cristine Borck Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, São Paulo, Brazil

Search for other papers by Patricia Cristine Borck in
Google Scholar
PubMed
Close
,
Sarah Rickli Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, São Paulo, Brazil

Search for other papers by Sarah Rickli in
Google Scholar
PubMed
Close
,
Jean Franciesco Vettorazzi Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, São Paulo, Brazil
Union Education of Cascavel, UNIVEL, Cascavel, Paraná, Brazil

Search for other papers by Jean Franciesco Vettorazzi in
Google Scholar
PubMed
Close
,
Thiago Martins Batista Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, São Paulo, Brazil

Search for other papers by Thiago Martins Batista in
Google Scholar
PubMed
Close
,
Antonio Carlos Boschero Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, São Paulo, Brazil

Search for other papers by Antonio Carlos Boschero in
Google Scholar
PubMed
Close
,
Elaine Vieira Postgraduate Program on Physical Education, Universidade Católica de Brasília-UCB, Distrito Federal, Brazil

Search for other papers by Elaine Vieira in
Google Scholar
PubMed
Close
, and
Everardo Magalhães Carneiro Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, São Paulo, Brazil

Search for other papers by Everardo Magalhães Carneiro in
Google Scholar
PubMed
Close

, corroborating with previous studies. Besides, the expression of Pck1, a key component of the gluconeogenesis program, was also increased at the beginning of the dark period. However, we observed lower glucose tolerance at night in mice fed to NP diet and

Restricted access
Leke Wiering Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Hepatology and Gastroenterology, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany
Berlin Institute of Health at Charité – Universitätsmedizin Berlin, BIH Biomedical Innovation Academy, BIH Charité Junior Clinician Scientist Program, Berlin, Germany

Search for other papers by Leke Wiering in
Google Scholar
PubMed
Close
and
Frank Tacke Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Hepatology and Gastroenterology, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany

Search for other papers by Frank Tacke in
Google Scholar
PubMed
Close

). FT’s lab received research grants from Gilead, Allergan, Bristol-Myers Squibb and Inventiva. Acknowledgements Dr Wiering is participant in the BIH Charité Junior Clinician Scientist Program funded by the Charité – Universitätsmedizin Berlin

Free access