Search Results
J Kwakkel
J Kwakkel
Department of Endocrinology and Metabolism, Academic Medical Center F5-165, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Search for other papers by J Kwakkel in
Google Scholar
PubMed
Search for other papers by J Kwakkel in
Google Scholar
PubMed
W M Wiersinga
W M Wiersinga
Department of Endocrinology and Metabolism, Academic Medical Center F5-165, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Search for other papers by W M Wiersinga in
Google Scholar
PubMed
Search for other papers by W M Wiersinga in
Google Scholar
PubMed
A Boelen
A Boelen
Department of Endocrinology and Metabolism, Academic Medical Center F5-165, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Search for other papers by A Boelen in
Google Scholar
PubMed
Search for other papers by A Boelen in
Google Scholar
PubMed
Introduction Increased serum levels of proinflammatory cytokines have been associated with nonthyroidal illness (NTI; Boelen et al. 1993 ), which is a state of altered thyroid hormone regulation and metabolism during illness
S Van der Geyten
S Van der Geyten
Search for other papers by S Van der Geyten in
Google Scholar
PubMed
Search for other papers by S Van der Geyten in
Google Scholar
PubMed
N Byamungu
N Byamungu
Search for other papers by N Byamungu in
Google Scholar
PubMed
Search for other papers by N Byamungu in
Google Scholar
PubMed
G E Reyns
G E Reyns
Search for other papers by G E Reyns in
Google Scholar
PubMed
Search for other papers by G E Reyns in
Google Scholar
PubMed
E R Kühn
E R Kühn
Search for other papers by E R Kühn in
Google Scholar
PubMed
Search for other papers by E R Kühn in
Google Scholar
PubMed
V M Darras
V M Darras
Search for other papers by V M Darras in
Google Scholar
PubMed
Search for other papers by V M Darras in
Google Scholar
PubMed
and exert its full biologic activity. This activation, as well a s the inactivation of thyroid hormones, occurs not in the thyroid, but in the periphery through the action of iodothyronine deiodinases ( Eales & Brown 1993 , Mol et al. 1997 , 1998
C R Liu
C R Liu
Key Laboratory of Hormones and Development, Department of Pathology, Ministry of Health China, Endocrinology Institute of Tianjin Medical University, Tianjin Medical Institute, Tianjin 300070, China
Search for other papers by C R Liu in
Google Scholar
PubMed
Search for other papers by C R Liu in
Google Scholar
PubMed
L Y Li
L Y Li
Search for other papers by L Y Li in
Google Scholar
PubMed
Search for other papers by L Y Li in
Google Scholar
PubMed
F Shi
F Shi
Search for other papers by F Shi in
Google Scholar
PubMed
Search for other papers by F Shi in
Google Scholar
PubMed
X Y Zang
X Y Zang
Search for other papers by X Y Zang in
Google Scholar
PubMed
Search for other papers by X Y Zang in
Google Scholar
PubMed
Y M Liu
Y M Liu
Key Laboratory of Hormones and Development, Department of Pathology, Ministry of Health China, Endocrinology Institute of Tianjin Medical University, Tianjin Medical Institute, Tianjin 300070, China
Search for other papers by Y M Liu in
Google Scholar
PubMed
Search for other papers by Y M Liu in
Google Scholar
PubMed
Y Sun
Y Sun
Search for other papers by Y Sun in
Google Scholar
PubMed
Search for other papers by Y Sun in
Google Scholar
PubMed
B H Kan
B H Kan
Search for other papers by B H Kan in
Google Scholar
PubMed
Search for other papers by B H Kan in
Google Scholar
PubMed
Introduction The heart is a major target organ for thyroid hormone (tri-iodothyronine, T 3 ) action. Thyroid hormone exerts its biological effects largely by influencing thyroid hormone-regulated gene expression via interactions with the high
Ana Sofia Rocha
Ana Sofia Rocha
IPATIMUP, Institute of Molecular Pathology and Immunology of the University of Porto, Rua Roberto Frias s/n, 4200-065 Porto, Portugal
Department of Pathology, Hospital São João, Porto, Portugal
Department of Pathology, Medical Faculty, University of São Paulo, São Paulo, Brazil
Department of Pathology, Medical Faculty, University of Porto, Porto, Portugal
Search for other papers by Ana Sofia Rocha in
Google Scholar
PubMed
Department of Pathology, Hospital São João, Porto, Portugal
Department of Pathology, Medical Faculty, University of São Paulo, São Paulo, Brazil
Department of Pathology, Medical Faculty, University of Porto, Porto, Portugal
Search for other papers by Ana Sofia Rocha in
Google Scholar
PubMed
Ricardo Marques
Ricardo Marques
IPATIMUP, Institute of Molecular Pathology and Immunology of the University of Porto, Rua Roberto Frias s/n, 4200-065 Porto, Portugal
Department of Pathology, Hospital São João, Porto, Portugal
Department of Pathology, Medical Faculty, University of São Paulo, São Paulo, Brazil
Department of Pathology, Medical Faculty, University of Porto, Porto, Portugal
Search for other papers by Ricardo Marques in
Google Scholar
PubMed
Department of Pathology, Hospital São João, Porto, Portugal
Department of Pathology, Medical Faculty, University of São Paulo, São Paulo, Brazil
Department of Pathology, Medical Faculty, University of Porto, Porto, Portugal
Search for other papers by Ricardo Marques in
Google Scholar
PubMed
Inês Bento
Inês Bento
IPATIMUP, Institute of Molecular Pathology and Immunology of the University of Porto, Rua Roberto Frias s/n, 4200-065 Porto, Portugal
Department of Pathology, Hospital São João, Porto, Portugal
Department of Pathology, Medical Faculty, University of São Paulo, São Paulo, Brazil
Department of Pathology, Medical Faculty, University of Porto, Porto, Portugal
Search for other papers by Inês Bento in
Google Scholar
PubMed
Department of Pathology, Hospital São João, Porto, Portugal
Department of Pathology, Medical Faculty, University of São Paulo, São Paulo, Brazil
Department of Pathology, Medical Faculty, University of Porto, Porto, Portugal
Search for other papers by Inês Bento in
Google Scholar
PubMed
Ricardo Soares
Ricardo Soares
IPATIMUP, Institute of Molecular Pathology and Immunology of the University of Porto, Rua Roberto Frias s/n, 4200-065 Porto, Portugal
Department of Pathology, Hospital São João, Porto, Portugal
Department of Pathology, Medical Faculty, University of São Paulo, São Paulo, Brazil
Department of Pathology, Medical Faculty, University of Porto, Porto, Portugal
Search for other papers by Ricardo Soares in
Google Scholar
PubMed
Department of Pathology, Hospital São João, Porto, Portugal
Department of Pathology, Medical Faculty, University of São Paulo, São Paulo, Brazil
Department of Pathology, Medical Faculty, University of Porto, Porto, Portugal
Search for other papers by Ricardo Soares in
Google Scholar
PubMed
João Magalhães
João Magalhães
IPATIMUP, Institute of Molecular Pathology and Immunology of the University of Porto, Rua Roberto Frias s/n, 4200-065 Porto, Portugal
Department of Pathology, Hospital São João, Porto, Portugal
Department of Pathology, Medical Faculty, University of São Paulo, São Paulo, Brazil
Department of Pathology, Medical Faculty, University of Porto, Porto, Portugal
Search for other papers by João Magalhães in
Google Scholar
PubMed
Department of Pathology, Hospital São João, Porto, Portugal
Department of Pathology, Medical Faculty, University of São Paulo, São Paulo, Brazil
Department of Pathology, Medical Faculty, University of Porto, Porto, Portugal
Search for other papers by João Magalhães in
Google Scholar
PubMed
Inês Vieira de Castro
Inês Vieira de Castro
IPATIMUP, Institute of Molecular Pathology and Immunology of the University of Porto, Rua Roberto Frias s/n, 4200-065 Porto, Portugal
Department of Pathology, Hospital São João, Porto, Portugal
Department of Pathology, Medical Faculty, University of São Paulo, São Paulo, Brazil
Department of Pathology, Medical Faculty, University of Porto, Porto, Portugal
Search for other papers by Inês Vieira de Castro in
Google Scholar
PubMed
Department of Pathology, Hospital São João, Porto, Portugal
Department of Pathology, Medical Faculty, University of São Paulo, São Paulo, Brazil
Department of Pathology, Medical Faculty, University of Porto, Porto, Portugal
Search for other papers by Inês Vieira de Castro in
Google Scholar
PubMed
Paula Soares
Paula Soares
IPATIMUP, Institute of Molecular Pathology and Immunology of the University of Porto, Rua Roberto Frias s/n, 4200-065 Porto, Portugal
Department of Pathology, Hospital São João, Porto, Portugal
Department of Pathology, Medical Faculty, University of São Paulo, São Paulo, Brazil
Department of Pathology, Medical Faculty, University of Porto, Porto, Portugal
Search for other papers by Paula Soares in
Google Scholar
PubMed
Department of Pathology, Hospital São João, Porto, Portugal
Department of Pathology, Medical Faculty, University of São Paulo, São Paulo, Brazil
Department of Pathology, Medical Faculty, University of Porto, Porto, Portugal
Search for other papers by Paula Soares in
Google Scholar
PubMed
( Castro et al. 2006 ). At variance with PTC, a mouse model for FTC was lacking until Kaneshige et al. (2000) described a mutant mouse with a mutation ( PV ) targeted to the thyroid hormone receptor β (THRB) locus. In a heterozygous condition
Shona Wood
Shona Wood
Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK
Search for other papers by Shona Wood in
Google Scholar
PubMed
Search for other papers by Shona Wood in
Google Scholar
PubMed
Andrew Loudon
Andrew Loudon
Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK
Search for other papers by Andrew Loudon in
Google Scholar
PubMed
Search for other papers by Andrew Loudon in
Google Scholar
PubMed
paradox. How might a pituitary target site be involved in remodelling of hypothalamic neuroendocrine circuits – the hallmark of the seasonal response? The answer to this lies in the remarkable discovery of thyroid hormones (THs) as key seasonal switches
Cássio M Villicev
Cássio M Villicev
Department of Anatomy, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof Lineu Prestes, 2415 Sao Paulo 05508-900, Brazil
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Cássio M Villicev in
Google Scholar
PubMed
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Cássio M Villicev in
Google Scholar
PubMed
Fatima R S Freitas
Fatima R S Freitas
Department of Anatomy, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof Lineu Prestes, 2415 Sao Paulo 05508-900, Brazil
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Fatima R S Freitas in
Google Scholar
PubMed
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Fatima R S Freitas in
Google Scholar
PubMed
Marcelo S Aoki
Marcelo S Aoki
Department of Anatomy, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof Lineu Prestes, 2415 Sao Paulo 05508-900, Brazil
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Marcelo S Aoki in
Google Scholar
PubMed
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Marcelo S Aoki in
Google Scholar
PubMed
Cássio Taffarel
Cássio Taffarel
Department of Anatomy, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof Lineu Prestes, 2415 Sao Paulo 05508-900, Brazil
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Cássio Taffarel in
Google Scholar
PubMed
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Cássio Taffarel in
Google Scholar
PubMed
Thomas S Scanlan
Thomas S Scanlan
Department of Anatomy, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof Lineu Prestes, 2415 Sao Paulo 05508-900, Brazil
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Thomas S Scanlan in
Google Scholar
PubMed
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Thomas S Scanlan in
Google Scholar
PubMed
Anselmo S Moriscot
Anselmo S Moriscot
Department of Anatomy, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof Lineu Prestes, 2415 Sao Paulo 05508-900, Brazil
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Anselmo S Moriscot in
Google Scholar
PubMed
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Anselmo S Moriscot in
Google Scholar
PubMed
Miriam O Ribeiro
Miriam O Ribeiro
Department of Anatomy, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof Lineu Prestes, 2415 Sao Paulo 05508-900, Brazil
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Miriam O Ribeiro in
Google Scholar
PubMed
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Miriam O Ribeiro in
Google Scholar
PubMed
Antonio C Bianco
Antonio C Bianco
Department of Anatomy, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof Lineu Prestes, 2415 Sao Paulo 05508-900, Brazil
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Antonio C Bianco in
Google Scholar
PubMed
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Antonio C Bianco in
Google Scholar
PubMed
Cecília H A Gouveia
Cecília H A Gouveia
Department of Anatomy, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof Lineu Prestes, 2415 Sao Paulo 05508-900, Brazil
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Cecília H A Gouveia in
Google Scholar
PubMed
School of Arts, Sciences & Humanities, University of Sao Paulo, Sao Paulo, Brazil
Department of Biosciences, Mackenzie Presbyterian University, Sao Paulo, Brazil
Departments of Pharmaceutical Chemistry & Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, SP, Brazil
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by Cecília H A Gouveia in
Google Scholar
PubMed
Introduction Thyroid hormone controls gene expression by interacting with nuclear receptors (TRs), which are hormone-inducible transcriptional factors ( Lazar 1993 ). Two genes encode TRs, TRα and TRβ ( Freedman 1992 ). At least two
E M de Vries
E M de Vries
Department of Endocrinology and Metabolism, Hypothalamic Integration Mechanisms, Laboratory of Endocrinology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Search for other papers by E M de Vries in
Google Scholar
PubMed
Search for other papers by E M de Vries in
Google Scholar
PubMed
H C van Beeren
H C van Beeren
Department of Endocrinology and Metabolism, Hypothalamic Integration Mechanisms, Laboratory of Endocrinology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Search for other papers by H C van Beeren in
Google Scholar
PubMed
Search for other papers by H C van Beeren in
Google Scholar
PubMed
M T Ackermans
M T Ackermans
Department of Endocrinology and Metabolism, Hypothalamic Integration Mechanisms, Laboratory of Endocrinology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Search for other papers by M T Ackermans in
Google Scholar
PubMed
Search for other papers by M T Ackermans in
Google Scholar
PubMed
A Kalsbeek
A Kalsbeek
Department of Endocrinology and Metabolism, Hypothalamic Integration Mechanisms, Laboratory of Endocrinology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Department of Endocrinology and Metabolism, Hypothalamic Integration Mechanisms, Laboratory of Endocrinology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Search for other papers by A Kalsbeek in
Google Scholar
PubMed
Department of Endocrinology and Metabolism, Hypothalamic Integration Mechanisms, Laboratory of Endocrinology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Search for other papers by A Kalsbeek in
Google Scholar
PubMed
E Fliers
E Fliers
Department of Endocrinology and Metabolism, Hypothalamic Integration Mechanisms, Laboratory of Endocrinology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Search for other papers by E Fliers in
Google Scholar
PubMed
Search for other papers by E Fliers in
Google Scholar
PubMed
A Boelen
A Boelen
Department of Endocrinology and Metabolism, Hypothalamic Integration Mechanisms, Laboratory of Endocrinology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Search for other papers by A Boelen in
Google Scholar
PubMed
Search for other papers by A Boelen in
Google Scholar
PubMed
). Spontaneous diminished food intake is known to be a part of a variety of illnesses, but has received only little attention as a potential mediator of the illness-induced changes in thyroid hormone (TH) homeostasis, despite its sometimes profound impact. For
Francisco J Arjona
Francisco J Arjona
Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands
Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands
Search for other papers by Francisco J Arjona in
Google Scholar
PubMed
Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands
Search for other papers by Francisco J Arjona in
Google Scholar
PubMed
Luis Vargas-Chacoff
Luis Vargas-Chacoff
Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands
Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands
Search for other papers by Luis Vargas-Chacoff in
Google Scholar
PubMed
Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands
Search for other papers by Luis Vargas-Chacoff in
Google Scholar
PubMed
María P Martín del Río
María P Martín del Río
Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands
Search for other papers by María P Martín del Río in
Google Scholar
PubMed
Search for other papers by María P Martín del Río in
Google Scholar
PubMed
Gert Flik
Gert Flik
Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands
Search for other papers by Gert Flik in
Google Scholar
PubMed
Search for other papers by Gert Flik in
Google Scholar
PubMed
Juan M Mancera
Juan M Mancera
Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands
Search for other papers by Juan M Mancera in
Google Scholar
PubMed
Search for other papers by Juan M Mancera in
Google Scholar
PubMed
Peter H M Klaren
Peter H M Klaren
Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands
Search for other papers by Peter H M Klaren in
Google Scholar
PubMed
Search for other papers by Peter H M Klaren in
Google Scholar
PubMed
Introduction Thyroid hormone regulates many important functions such as growth, salinity preference, oxygen consumption, nutrient metabolism, and metamorphosis in fish (reviewed by Eales (2006) and Blanton & Specker (2007) ). Under normal
Sean C Lema
Sean C Lema
Search for other papers by Sean C Lema in
Google Scholar
PubMed
Search for other papers by Sean C Lema in
Google Scholar
PubMed
Jon T Dickey
Jon T Dickey
Physiology Program, School of Aquatic and Fishery Sciences, Pacific Northwest Division, Northwest Fisheries Science Center, NOAA Fisheries, Seattle, Washington 98112, USA
Search for other papers by Jon T Dickey in
Google Scholar
PubMed
Search for other papers by Jon T Dickey in
Google Scholar
PubMed
Irvin R Schultz
Irvin R Schultz
Physiology Program, School of Aquatic and Fishery Sciences, Pacific Northwest Division, Northwest Fisheries Science Center, NOAA Fisheries, Seattle, Washington 98112, USA
Search for other papers by Irvin R Schultz in
Google Scholar
PubMed
Search for other papers by Irvin R Schultz in
Google Scholar
PubMed
Penny Swanson
Penny Swanson
Search for other papers by Penny Swanson in
Google Scholar
PubMed
Search for other papers by Penny Swanson in
Google Scholar
PubMed
Introduction The hypothalamic–pituitary–thyroid (HPT) axis regulates metabolism and growth, reproduction, and brain development in vertebrates. Similarly, in fish, thyroid hormones (THs) have been demonstrated to regulate growth ( Huang et al
Aijun Zhang
Aijun Zhang
Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA
Search for other papers by Aijun Zhang in
Google Scholar
PubMed
Search for other papers by Aijun Zhang in
Google Scholar
PubMed
Douglas H Sieglaff
Douglas H Sieglaff
Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA
Search for other papers by Douglas H Sieglaff in
Google Scholar
PubMed
Search for other papers by Douglas H Sieglaff in
Google Scholar
PubMed
Jean Philippe York
Jean Philippe York
Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA
Search for other papers by Jean Philippe York in
Google Scholar
PubMed
Search for other papers by Jean Philippe York in
Google Scholar
PubMed
Ji Ho Suh
Ji Ho Suh
Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA
Search for other papers by Ji Ho Suh in
Google Scholar
PubMed
Search for other papers by Ji Ho Suh in
Google Scholar
PubMed
Stephen D Ayers
Stephen D Ayers
Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA
Search for other papers by Stephen D Ayers in
Google Scholar
PubMed
Search for other papers by Stephen D Ayers in
Google Scholar
PubMed
Glenn E Winnier
Glenn E Winnier
Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA
Search for other papers by Glenn E Winnier in
Google Scholar
PubMed
Search for other papers by Glenn E Winnier in
Google Scholar
PubMed
Alexei Kharitonenkov
Alexei Kharitonenkov
Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA
Search for other papers by Alexei Kharitonenkov in
Google Scholar
PubMed
Search for other papers by Alexei Kharitonenkov in
Google Scholar
PubMed
Christopher Pin
Christopher Pin
Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA
Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA
Search for other papers by Christopher Pin in
Google Scholar
PubMed
Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA
Search for other papers by Christopher Pin in
Google Scholar
PubMed
Pumin Zhang
Pumin Zhang
Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA
Search for other papers by Pumin Zhang in
Google Scholar
PubMed
Search for other papers by Pumin Zhang in
Google Scholar
PubMed
Paul Webb
Paul Webb
Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA
Search for other papers by Paul Webb in
Google Scholar
PubMed
Search for other papers by Paul Webb in
Google Scholar
PubMed
Xuefeng Xia
Xuefeng Xia
Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA
Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA
Search for other papers by Xuefeng Xia in
Google Scholar
PubMed
Houston Methodist Research Institute, College of Arts and Sciences, Departments of Paediatrics, Children's Health Research Institute, Department of Molecular Physiology and Biophysics, The Third Affiliated Hospital of Guangzhou Medical University, Genomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USA
Search for other papers by Xuefeng Xia in
Google Scholar
PubMed
these concerns, it is important to understand how to manage local production of FGF21 in desired target tissues and the consequences of changes in FGF21 concentrations. Thyroid hormones (THs) act as master regulators of metabolism and there is evidence
