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RANKL. RANKL is the ligand for receptor activator of nuclear factor-kappaB (RANK) and is induced by progesterone ( Fata et al. 2000 , Brisken et al. 2002 ). Pax-2 is a proto-oncogene transcription factor characterized by a paired domain and

signaling in cardiomyocytes will help elucidate how hormonal signaling modulates myocardial function. Insulin and IGF-I could prevent skeletal muscle cell atrophy and promote myogenesis through forkhead transcription factors (FOXO; Hribal et al

production which acts by regulating stromal COUP-TFII signaling to promote decidualization. In another example, conditional deletion of the ER gene in the uterine epithelial compartment leads to loss of LIF production. Furthermore, the transcription factor

that GPR30 signaling triggers lead to the induced expression of c-fos in macrophages ( Kanda & Watanabe 2003 a ) and activation of the transcription factor CREB in keratinocytes ( Kanda & Watanabe 2003 b , 2004 ). These in turn activate the

defined in the human POMC promoter, domain IV (−376 to −417) had the distinctive property of being active in DMS-79 cells but not in AtT-20 cells ( Picon et al. 1995 ). It was reported that E2 transcription factor binding was required for the activity of

Introduction Insulin gene transcription is regulated by both the ubiquitous and the β-cell-specific transcription factors ( Melloul et al . 2002 , Brink 2003 ). In β-cells, multiple regulatory elements in the basal insulin promoter control insulin

differentiate into pancreatic, exocrine, ductal and endocrine cells in culture. A recent publication showed that suppression of nestin expression in embryonic stem cells by gene silencing reduced endodermal and pancreatic transcription factor expression ( Kim

by first binding to the GH receptor (GHR) and then triggering signal transduction cascades resulting in physiological responses ( Argetsinger & Carter-Su 1996 ). Although several transcription factors were believed to be involved in GH signaling

( Wen et al . 2013 ) and that the induction of VEGF was mediated by binding of the transcription factor AR and SP1 to the core promoter region of VEGF ( Eisermann et al . 2013 ). Androgen deprivation therapy (ADT), the standard treatment for advanced

-producing cells in vitro . To achieve this, nuclear receptor subfamily 5, group A, member 1 ( NF5A1 that was previously known as SF-1 or AD4BP ) is a key molecule. NF5A1 is the steroidogenic tissue-specific transcription factor that controls the expression