analyzer (Abbott). Serum folate was quantified by time-resolved fluoroimmunoassay using an AutoDelfia automated analyzer (PerkinElmer Life and Analytical Sciences, Wallac Oy, Turku, Finland). Plasma insulin, leptin, and adiponectin were quantified by ELISA
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Elisa Keating, Ana Correia-Branco, João R Araújo, Manuela Meireles, Rita Fernandes, Luísa Guardão, João T Guimarães, Fátima Martel, and Conceição Calhau
Min Liu, Shuo Xie, Weiwei Liu, Jingjin Li, Chao Li, Wei Huang, Hexin Li, Jinghai Song, and Hong Zhang
, thus contributing to obesity ( Fasshauer & Bluher 2015 ). Adiponectin and leptin are two major adipokines involved in regulating body fat homeostasis and insulin sensitivity ( Kadowaki et al . 2006 , Rosenbaum & Leibel 2014 ). Two decades of
Cid Pitombo, Eliana P Araújo, Cláudio T De Souza, José C Pareja, Bruno Geloneze, and Lício A Velloso
visceral production of glycerol ( Williamson et al. 1966 ), and abnormal production of adipose tissue-derived hormones and cyto-kines, such as tumour necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6, leptin, adiponectin, and resistin ( Hotamisligil et
M A Hyatt, D H Keisler, H Budge, and M E Symonds
to be established in early life and is associated with a state of chronic low-grade inflammation where pro-inflammatory cytokines such as interleukin 6 (IL6) are raised, whilst anti-inflammatory markers including adiponectin are decreased in
Patricia K Russell, Salvatore Mangiafico, Barbara C Fam, Michele V Clarke, Evelyn S Marin, Sofianos Andrikopoulos, Kristine M Wiren, Jeffrey D Zajac, and Rachel A Davey
visceral and subcutaneous fat pad mass in Global-ARKOs is characterised by an increase in the number of large adipocytes, as well as increased serum leptin and adiponectin levels and decreased voluntary activity in the absence of insulin resistance ( Rana
K Alexander H Iwen, Oezge Senyaman, Arne Schwartz, Maren Drenckhan, Britta Meier, Dirk Hadaschik, and Johannes Klein
% after 4 h of ACTH stimulation ( P <0.01). This effect lasted for another 4 h ( Fig. 4 A). Adiponectin mRNA concentrations displayed a similar pattern, ACTH significantly decreased adiponectin mRNA levels by 22% after treatment for 2 h ( P <0.05). This
A P Santos-Silva, E Oliveira, C R Pinheiro, A C Santana, C C Nascimento-Saba, Y Abreu-Villaça, E G Moura, and P C Lisboa
Pharmaceuticals, Inc, Burlingame, CA, USA) Adiponectin 0.155 ng/ml 2 EIA kit (Millipore, Billerica, MA, USA) Adrenal catecholamine content measurement For this, left adrenal gland was homogenized in 500 μl 10% acetic acid and centrifuged at 1120 g for 5 min. To
Nava Chapnik, Yoni Genzer, Avraham Ben-Shimon, Masha Y Niv, and Oren Froy
). In peripheral tissues, AMPK is phosphorylated and activated under elevated AMP levels by liver kinase B1 (LKB1; Sanders et al . 2007 ) following hormonal signals, such as adiponectin ( Yoon et al . 2006 ). Consequently, activated AMPK
Qinghua Wang, Jing Tang, Shujun Jiang, Zan Huang, Anying Song, Siyuan Hou, Xiang Gao, and Hai-Bin Ruan
in KO adipose tissue ( Fig. 4 ), levels of serum LEPTIN ( Fig. 5E and F ) and ADIPONECTIN ( Fig. 5G and H ) in KO mice were higher than WT mice, even before obesity was apparent. However, we did not observe any changes in serum levels of
Bethany P Cummings, Andrew A Bremer, Timothy J Kieffer, David D'Alessio, and Peter J Havel
), proinsulin (B), glucagon (C), and leptin (D). +++ P <0.001, + P <0.05 by one-factor ANOVA, *** P <0.001, * P <0.05 by Bonferroni's posttest compared with baseline. Changes of circulating leptin and adiponectin levels were also assessed. Similar to what has
