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Han Yan
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Matthew Mitschelen
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Georgina V Bixler Reynolds Oklahoma Center on Aging, Genome Sciences Facility, Donald W. Reynolds Department of Geriatric Medicine, University of Oklahoma Health Sciences Center, 975 NE 10th ST BRC 1305, Oklahoma City, Oklahoma 73104, USA

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Robert M Brucklacher Reynolds Oklahoma Center on Aging, Genome Sciences Facility, Donald W. Reynolds Department of Geriatric Medicine, University of Oklahoma Health Sciences Center, 975 NE 10th ST BRC 1305, Oklahoma City, Oklahoma 73104, USA

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Julie A Farley
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Song Han
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Willard M Freeman Reynolds Oklahoma Center on Aging, Genome Sciences Facility, Donald W. Reynolds Department of Geriatric Medicine, University of Oklahoma Health Sciences Center, 975 NE 10th ST BRC 1305, Oklahoma City, Oklahoma 73104, USA

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William E Sonntag
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at peak levels. We hypothesized that brain IGF1 protein expression is highly regulated by uptake of circulating IGF1 across the blood–brain barrier and/or by paracrine IGF1 gene expression in brain. To date, the effects of alterations in peripheral GH

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-11-0200
Volume/Issue:
Volume 211: Issue 1
Free access
Ling-Chu Chang Immunogenetics Laboratory, Department of Animal Science, Michigan State University, East Lansing, MI 48824, USA

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Sally A Madsen Immunogenetics Laboratory, Department of Animal Science, Michigan State University, East Lansing, MI 48824, USA

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Trine Toelboell Immunogenetics Laboratory, Department of Animal Science, Michigan State University, East Lansing, MI 48824, USA

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Patty S D Weber Immunogenetics Laboratory, Department of Animal Science, Michigan State University, East Lansing, MI 48824, USA

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Jeanne L Burton Immunogenetics Laboratory, Department of Animal Science, Michigan State University, East Lansing, MI 48824, USA

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-dependent and GR-mediated downregulation of Fas gene expression in bovine blood neutrophils, with corresponding reductions in surface Fas expression, caspase 8 activity and rate of apoptosis in vitro , and increases in circulating cell numbers in vivo

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.05822
Volume/Issue:
Volume 183: Issue 3
Free access
Joëlle Dupont PRC (UMR 6175), Station de Recherches Avicoles (UR 83), INSERM, Department of Animal and Avian Sciences, Department of Animal and Food Sciences, INRA, 37380 Nouzilly, France

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Sophie Tesseraud PRC (UMR 6175), Station de Recherches Avicoles (UR 83), INSERM, Department of Animal and Avian Sciences, Department of Animal and Food Sciences, INRA, 37380 Nouzilly, France

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Michel Derouet PRC (UMR 6175), Station de Recherches Avicoles (UR 83), INSERM, Department of Animal and Avian Sciences, Department of Animal and Food Sciences, INRA, 37380 Nouzilly, France

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Anne Collin PRC (UMR 6175), Station de Recherches Avicoles (UR 83), INSERM, Department of Animal and Avian Sciences, Department of Animal and Food Sciences, INRA, 37380 Nouzilly, France

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Nicole Rideau PRC (UMR 6175), Station de Recherches Avicoles (UR 83), INSERM, Department of Animal and Avian Sciences, Department of Animal and Food Sciences, INRA, 37380 Nouzilly, France

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Sabine Crochet PRC (UMR 6175), Station de Recherches Avicoles (UR 83), INSERM, Department of Animal and Avian Sciences, Department of Animal and Food Sciences, INRA, 37380 Nouzilly, France

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Estelle Godet PRC (UMR 6175), Station de Recherches Avicoles (UR 83), INSERM, Department of Animal and Avian Sciences, Department of Animal and Food Sciences, INRA, 37380 Nouzilly, France

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Estelle Cailleau-Audouin PRC (UMR 6175), Station de Recherches Avicoles (UR 83), INSERM, Department of Animal and Avian Sciences, Department of Animal and Food Sciences, INRA, 37380 Nouzilly, France

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Sonia Métayer-Coustard PRC (UMR 6175), Station de Recherches Avicoles (UR 83), INSERM, Department of Animal and Avian Sciences, Department of Animal and Food Sciences, INRA, 37380 Nouzilly, France

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Michel J Duclos PRC (UMR 6175), Station de Recherches Avicoles (UR 83), INSERM, Department of Animal and Avian Sciences, Department of Animal and Food Sciences, INRA, 37380 Nouzilly, France

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Christian Gespach PRC (UMR 6175), Station de Recherches Avicoles (UR 83), INSERM, Department of Animal and Avian Sciences, Department of Animal and Food Sciences, INRA, 37380 Nouzilly, France

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Tom E Porter PRC (UMR 6175), Station de Recherches Avicoles (UR 83), INSERM, Department of Animal and Avian Sciences, Department of Animal and Food Sciences, INRA, 37380 Nouzilly, France

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Larry A Cogburn PRC (UMR 6175), Station de Recherches Avicoles (UR 83), INSERM, Department of Animal and Avian Sciences, Department of Animal and Food Sciences, INRA, 37380 Nouzilly, France

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Jean Simon PRC (UMR 6175), Station de Recherches Avicoles (UR 83), INSERM, Department of Animal and Avian Sciences, Department of Animal and Food Sciences, INRA, 37380 Nouzilly, France

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investigated the effect of insulin immuno-neutralization on insulin signaling cascade (including GSK3) and gene expression in the liver and the muscle in order to evaluate the action of insulin in fed chickens. Materials and Methods Experimental protocol One

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0055
Volume/Issue:
Volume 197: Issue 3
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Kuladip Jana Garrison Institute on Aging, Department of Cell Biology and Biochemistry, Department of Nutrition Sciences, Department of Neuropsychiatry

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Xiangling Yin Garrison Institute on Aging, Department of Cell Biology and Biochemistry, Department of Nutrition Sciences, Department of Neuropsychiatry

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Randolph B Schiffer Garrison Institute on Aging, Department of Cell Biology and Biochemistry, Department of Nutrition Sciences, Department of Neuropsychiatry

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Jau-Jiin Chen Garrison Institute on Aging, Department of Cell Biology and Biochemistry, Department of Nutrition Sciences, Department of Neuropsychiatry

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Akhilesh K Pandey Garrison Institute on Aging, Department of Cell Biology and Biochemistry, Department of Nutrition Sciences, Department of Neuropsychiatry

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Douglas M Stocco Garrison Institute on Aging, Department of Cell Biology and Biochemistry, Department of Nutrition Sciences, Department of Neuropsychiatry

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Paula Grammas Garrison Institute on Aging, Department of Cell Biology and Biochemistry, Department of Nutrition Sciences, Department of Neuropsychiatry

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XingJia Wang Garrison Institute on Aging, Department of Cell Biology and Biochemistry, Department of Nutrition Sciences, Department of Neuropsychiatry

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StAR gene expression, and the level of StAR protein in Leydig cells significantly affects testosterone production ( Stocco 2001 ). However, StAR protein level also declines during Leydig cell aging, and mitochondrial cholesterol transfer in aged rat

Article Type:
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DOI:
https://doi.org/10.1677/JOE-07-0282
Volume/Issue:
Volume 197: Issue 2
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Yong Zhang State Key Laboratory of Biocontrol, Department of Biochemistry, College of Ocean, School of Life Sciences, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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Yun Liu State Key Laboratory of Biocontrol, Department of Biochemistry, College of Ocean, School of Life Sciences, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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Xigui Huang State Key Laboratory of Biocontrol, Department of Biochemistry, College of Ocean, School of Life Sciences, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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Xiaochun Liu State Key Laboratory of Biocontrol, Department of Biochemistry, College of Ocean, School of Life Sciences, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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Baowei Jiao State Key Laboratory of Biocontrol, Department of Biochemistry, College of Ocean, School of Life Sciences, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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Zining Meng State Key Laboratory of Biocontrol, Department of Biochemistry, College of Ocean, School of Life Sciences, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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Pei Zhu State Key Laboratory of Biocontrol, Department of Biochemistry, College of Ocean, School of Life Sciences, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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Shuisheng Li State Key Laboratory of Biocontrol, Department of Biochemistry, College of Ocean, School of Life Sciences, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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Haoran Lin State Key Laboratory of Biocontrol, Department of Biochemistry, College of Ocean, School of Life Sciences, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China
State Key Laboratory of Biocontrol, Department of Biochemistry, College of Ocean, School of Life Sciences, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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Christopher H K Cheng State Key Laboratory of Biocontrol, Department of Biochemistry, College of Ocean, School of Life Sciences, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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alternative splicing of the same gene. We have also demonstrated that this phenomenon is conserved in a variety of vertebrates from teleosts to mammals. The two seabream GPR39 receptors were studied by transfection in cultured HEK293 cells and their expression

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-07-0608
Volume/Issue:
Volume 199: Issue 3
Free access
Rohit Singhal Physiology and Biophysics, Arkansas Children's Nutrition Center, Departments of

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Kartik Shankar Physiology and Biophysics, Arkansas Children's Nutrition Center, Departments of
Physiology and Biophysics, Arkansas Children's Nutrition Center, Departments of

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Thomas M Badger Physiology and Biophysics, Arkansas Children's Nutrition Center, Departments of
Physiology and Biophysics, Arkansas Children's Nutrition Center, Departments of

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Martin J Ronis Physiology and Biophysics, Arkansas Children's Nutrition Center, Departments of
Physiology and Biophysics, Arkansas Children's Nutrition Center, Departments of

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E 2 using uterine wet weight and hepatic gene expression profile. Materials and Methods Animal care and experiment design The experiment received prior approval from the Institutional Animal Care and Use Committee at UAMS. Adult female Sprague

Article Type:
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DOI:
https://doi.org/10.1677/JOE-09-0059
Volume/Issue:
Volume 202: Issue 1
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Smithamol Sithara Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Australia

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Tamsyn M Crowley School of Medicine, MMR, Bioinformatics Core Research Facility, Deakin University, Geelong, Australia

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Ken Walder Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Australia

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Kathryn Aston-Mourney Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Australia

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effective. Therefore, a novel approach is necessary for the identification of new antidiabetic drugs that does not focus on a single specific target, but instead integrates the overall complexity of the disease. Gene expression signature (GES): a

Article Type:
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DOI:
https://doi.org/10.1530/JOE-16-0515
Volume/Issue:
Volume 232: Issue 2
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Dario R Lemos Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of

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Jodi L Downs Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of
Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of
Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of

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Martin N Raitiere Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of

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Henryk F Urbanski Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of
Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of
Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of

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al . 2008 ). Furthermore, light itself exerts a remarkable effect on adrenal physiology; in mice, light exposure at night induces both gene expression and the secretion of corticosterone, through a pathway that involves the SCN and the sympathetic

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0437
Volume/Issue:
Volume 201: Issue 2
Free access
Ingrid Segers Follicle Biology Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Jette, Belgium

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Tom Adriaenssens Follicle Biology Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Jette, Belgium

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Sandra Wathlet Follicle Biology Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Jette, Belgium

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Johan Smitz Follicle Biology Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Jette, Belgium

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-hMG) is mainly represented by hCG stimulation ( Wolfenson et al . 2005 ). More recently, recombinant LH (rLH) became available to complement recombinant FSH (rFSH) during stimulation ( Mochtar et al . 2007 ). Differences in gene expression in human

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0150
Volume/Issue:
Volume 215: Issue 2
Free access
Xigui Huang Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Science, Southwest University, Chongqing 400715, China
Department of Biochemistry and
The Environmental Science Programme, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China
State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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Baowei Jiao Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Science, Southwest University, Chongqing 400715, China
Department of Biochemistry and
The Environmental Science Programme, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China
State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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Chun Kit Fung Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Science, Southwest University, Chongqing 400715, China
Department of Biochemistry and
The Environmental Science Programme, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China
State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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Yong Zhang Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Science, Southwest University, Chongqing 400715, China
Department of Biochemistry and
The Environmental Science Programme, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China
State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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Walter K K Ho Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Science, Southwest University, Chongqing 400715, China
Department of Biochemistry and
The Environmental Science Programme, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China
State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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Chi Bun Chan Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Science, Southwest University, Chongqing 400715, China
Department of Biochemistry and
The Environmental Science Programme, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China
State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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Haoran Lin Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Science, Southwest University, Chongqing 400715, China
Department of Biochemistry and
The Environmental Science Programme, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China
State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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Deshou Wang Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Science, Southwest University, Chongqing 400715, China
Department of Biochemistry and
The Environmental Science Programme, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China
State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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Christopher H K Cheng Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Science, Southwest University, Chongqing 400715, China
Department of Biochemistry and
The Environmental Science Programme, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China
State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou 510275, China

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signal transduction mechanisms of the two PRLRs, as well as their in vivo regulation of gene expression by steroid hormones. We have also cloned the promoters of these two genes in black seabream and studied their responsiveness to steroid hormone

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-07-0076
Volume/Issue:
Volume 194: Issue 2
Free access