, Niwa et al. 1999 ). cAMP might act upstream of caspase-3 activation to delay the activation of the apoptotic pathway as has been postulated in human neutrophils ( Parvathenani et al. 1998 , Niwa et al. 1999 ). Eventually, such an anti
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K A Slot, M de Boer-Brouwer, M Houweling, A B Vaandrager, J H Dorrington, and K J Teerds
Ángela Sánchez, Constanza Contreras-Jurado, Diego Rodríguez, Javier Regadera, Susana Alemany, and Ana Aranda
-lymphocytes (CD3 + ), monocytes (CD115 + ) and neutrophils (Lyg6G + ) was determined in Wt and KO mice. (B) Number of total TER119 and CD45 positive cells in control (Ctrl) and hypothyroid (Hypo) mice ( n = 5). Circulating number of B-lymphocytes, T
Michela Campolo, Akbar Ahmad, Rosalia Crupi, Daniela Impellizzeri, Rossana Morabito, Emanuela Esposito, and Salvatore Cuzzocrea
via a diffusion-limited reaction of superoxide and NO, which damages biomolecules by nitrotyrosine formation. The expression of iNOS has been found near the necrotic and inflammatory areas mainly in neutrophils/macrophages, where it plays a crucial
Craig S Nunemaker, H Grace Chung, Gretchen M Verrilli, Kathryn L Corbin, Aditi Upadhye, and Poonam R Sharma
hyperglycemia: C-X-C motif ligand 1 (CXCL1) and CXCL5. Both CXCL1 and CXCL5 bind with the CXCR2 receptor and are associated with processes as diverse as angiogenesis, wound healing, and tumorigenesis. CXCL1 is expressed in macrophages, neutrophils, and
Nailliw Z Preite, Bruna P P do Nascimento, Cynthia R Muller, Anna Laura V Américo, Talita S Higa, Fabiana S Evangelista, Carmen L Lancellotti, Felipe dos Santos Henriques, Miguel Luiz Batista Jr, Antonio C Bianco, and Miriam O Ribeiro
2 O 2 in methanol and blocking of free protein-binding sites with 5% normal goat serum, sections were immune stained for immune cells: macrophages with CD68 anti-mouse KP-1 monoclonal antibody (Abcam, ab955), neutrophils with CD11b (Abcam, ab75476
Maayan Vatarescu, Sapir Bechor, Yulia Haim, Tal Pecht, Tanya Tarnovscki, Noa Slutsky, Ori Nov, Hagit Shapiro, Avishai Shemesh, Angel Porgador, Nava Bashan, and Assaf Rudich
. 2010 ). In mouse models amenable to detailed time-course analyses, even short-term (3 days) high-fat feeding (HFF) induced neutrophil-dominated adipose tissue inflammation. This inflammatory response clearly occurred before the development of obesity
Daniella B R Insuela, Julio B Daleprane, Luciana P Coelho, Adriana R Silva, Patrícia M R e Silva, Marco A Martins, and Vinicius F Carvalho
determine the percentage of mononuclear cells and neutrophils. Invasive assessment of respiratory mechanics Mice were anesthetized (nembutal 60 mg/kg, i.p.) and subjected to both endotracheal and esophageal intubations for pulmonary function and airway
Andrés Quintanar-Stephano, Roberto Chavira-Ramírez, Kalman Kovacs, and Istvan Berczi
perivascular areas (perivascular cuffs) in the white matter. The typical infiltrate consists of T lymphocytes, plasma cells, macrophages, polymorphonuclear neutrophils and eosinophilic leucocytes. Tissue demyelination is almost completely absent in the acute
Sy-Ying Leu, Yi-Ling Tsang, Li-Chun Ho, Ching-Chun Yang, Ai-Ning Shao, Chia-Yu Chang, Hui-Kuan Lin, Pei-Jane Tsai, Junne-Ming Sung, and Yau-Sheng Tsai
an acute-phase serum protein produced by hepatocytes and adipose tissues. SAA induces the secretion of IL-1B from macrophages, dendritic cells, and neutrophils by activating the NLRP3 inflammasome and caspase-1 ( Niemi et al. 2011 , Shridas et al
Mark O Huising, Corine P Kruiswijk, and Gert Flik
constitute an essential component of innate immunity and respond rapidly to local pathogenic insults by local margination. The circulating neutrophil population is short lived and is continuously replenished from the bone marrow haematopoietic precursor
