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Department of Medicine (Austin Health/Northern Health), Department of Physiology, Gynecological Endocrinology Unit, Heidelberg Repatriation Hospital, The University of Melbourne, 300 Waterdale Road, Heidelberg Heights, Melbourne, Victoria 3081, Australia
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were analyzed in detail. The follicles were counted and classified as healthy or atretic ( Brawer et al . 1986 , Convery et al . 1990 ). Preantral follicles were defined as follicles without any antral cavity and with two or more layers of granulosa
Andrology Laboratory, ANZAC Research Institute, University of Sydney, Sydney, New South Wales, Australia
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cells of preantral follicles, but during antral follicular growth, AR expression progressively declines in the outer mural granulosa cells but remains intense in the cumulus cells ( Szoltys & Slomczynska 2000 , Lenie & Smitz 2009 ) ( Fig. 1
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. In addition, the signals for EP4 mRNA were localized mostly to oocytes in the preantral follicles ( Segi et al. 2003 ). It is possible that PGE2 produced via cPGES may act through EP4 in the mouse oocytes. Although the expression patterns
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implants of diethylstilbesterol (DES) was followed by implant withdrawal-induced apoptosis of granulosa cells in multilayered preantral follicles ( Billig et al. 1993 ). The mechanism for this effect of oestrogen in promoting granulosa cell viability was
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Australian Institute of Musculoskeletal Science, Victoria University, St. Albans, Victoria, Australia
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Australian Institute of Musculoskeletal Science, Victoria University, St. Albans, Victoria, Australia
Monash Centre for Health Research and Implementation, Monash University and Monash Health, Clayton, Victoria, Australia
Medicine at Western Health, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia
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, indicating distinct roles for AR-mediated actions during the various stages of follicular development. Generally, AR expression is present as follicles enter the growing pool and is expressed in the oocyte, granulosa cells and theca cells of preantral
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Centre for Neuroendocrinology, University of Otago, Dunedin, New Zealand
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Brain Health Research Centre, University of Otago, Dunedin, New Zealand
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Centre for Neuroendocrinology, University of Otago, Dunedin, New Zealand
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Woodcock SR Oorschot DE Batchelor NJ 2018 Anti-Mullerian hormone overexpression restricts preantral ovarian follicle survival . Journal of Endocrinology 237 153 – 163 . ( https://doi.org/10.1530/JOE-18-0005 ) 29540452 Percie du Sert N Ahluwalia
Laboratory for Reproductive Immunology, Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Department of Reproductive Medicine, Hospital and Institute of Obstetrics and Gynecology, Fudan University Shanghai Medical College, No. 413, Zhaozhou Road, Shanghai 200011, China
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Laboratory for Reproductive Immunology, Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Department of Reproductive Medicine, Hospital and Institute of Obstetrics and Gynecology, Fudan University Shanghai Medical College, No. 413, Zhaozhou Road, Shanghai 200011, China
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Laboratory for Reproductive Immunology, Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Department of Reproductive Medicine, Hospital and Institute of Obstetrics and Gynecology, Fudan University Shanghai Medical College, No. 413, Zhaozhou Road, Shanghai 200011, China
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Laboratory for Reproductive Immunology, Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Department of Reproductive Medicine, Hospital and Institute of Obstetrics and Gynecology, Fudan University Shanghai Medical College, No. 413, Zhaozhou Road, Shanghai 200011, China
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Laboratory for Reproductive Immunology, Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Department of Reproductive Medicine, Hospital and Institute of Obstetrics and Gynecology, Fudan University Shanghai Medical College, No. 413, Zhaozhou Road, Shanghai 200011, China
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Laboratory for Reproductive Immunology, Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Department of Reproductive Medicine, Hospital and Institute of Obstetrics and Gynecology, Fudan University Shanghai Medical College, No. 413, Zhaozhou Road, Shanghai 200011, China
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in preantral granulosa cells, but not in cumulus or mural cells of the pre-ovulatory follicles, in the mouse ovary. However, very little is known about PC expression and functions in human granulosa cells. Only one recent study ( Akiyama et al . 2012
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Helen Wills Neuroscience Institute, UC Berkeley, Berkeley, California, USA
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was performed as previously described ( Lara et al . 2000 ). All follicular structures were followed through all the slices. Briefly, preantral follicles correspond to follicles without any antral cavity, including primary and secondary follicles
Departments of, Physiology and Biophysics, Pharmacology, Cell and Development of Biology, Department of Biological Sciences, Institute of Biomedical Sciences
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found between the ovaries from female rats submitted to high-fat diet for 180 days and their controls. In the control group, the ovaries exhibited morphologically normal antral and pre-antral follicles and corpora lutea. The granulosa layer showed a
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Departments of Biochemistry and Biomedical Sciences, Pediatrics, Obstetrics and Gynecology, McMaster University, 1280 Main Street West HSC 4H30A, Hamilton, Ontario, Canada L8S 4K1
Departments of Biochemistry and Biomedical Sciences, Pediatrics, Obstetrics and Gynecology, McMaster University, 1280 Main Street West HSC 4H30A, Hamilton, Ontario, Canada L8S 4K1
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delayed onset of puberty ( Guzman et al . 2006 ). After puberty, offspring born to lactationally protein restricted dams display increased numbers of preantral and small antral follicles but reduced numbers of primordial follicles, Graafian follicles, and