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Edouard G A Mills Section of Endocrinology and Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK

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Waljit S Dhillo Section of Endocrinology and Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK

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Alexander N Comninos Section of Endocrinology and Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
Department of Endocrinology, Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, UK

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and number ( Rometo et al. 2007 ). Further studies demonstrate a sexual dimorphism with significantly more kisspeptin fibres in the infundibular nucleus and rostral preoptic area in women compared to men ( Hrabovszky et al. 2010 ). Extra

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-18-0269
Volume/Issue:
Volume 239: Issue 1
Free access
Shisan Xu Department of Biomedical Sciences, College of Veterinary Medicine and Life Science, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Fangjing Xie Department of Biomedical Sciences, College of Veterinary Medicine and Life Science, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Li Tian Department of Biomedical Sciences, College of Veterinary Medicine and Life Science, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Samane Fallah Department of Biomedical Sciences, College of Veterinary Medicine and Life Science, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Fatemeh Babaei Department of Chemistry, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Sinai H C Manno Department of Biomedical Sciences, College of Veterinary Medicine and Life Science, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Francis A M Manno III School of Biomedical Engineering, Faculty of Engineering, University of Sydney, Sydney, New South Wales, Australia

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Lina Zhu Department of Biomedical Sciences, College of Veterinary Medicine and Life Science, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Kin Fung Wong Department of Biomedical Engineering, Polytechnic University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Yimin Liang Department of Chemistry, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Rajkumar Ramalingam Department of Chemistry, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Lei Sun Department of Biomedical Engineering, Polytechnic University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Xin Wang Department of Biomedical Sciences, College of Veterinary Medicine and Life Science, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Robert Plumb Waters Technologies Corporation, Milford, Massachusetts, USA

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Lee Gethings Waters Technologies Corporation, Milford, Massachusetts, USA

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Yun Wah Lam Department of Chemistry, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Shuk Han Cheng Department of Biomedical Sciences, College of Veterinary Medicine and Life Science, City University of Hong Kong, Hong Kong SAR, People’s Republic of China
State Key Laboratory of Marine Pollution (SKLMP) at City University of Hong Kong, Hong Kong SAR, People’s Republic of China
Department of Materials Science and Engineering, College of Science and Engineering, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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sex (usually male) and sexual differences in regeneration have never been investigated. In the present study, we examine, for the first time, sexual dimorphism of zebrafish heart regeneration and factors that influence the rate of cardiac regeneration

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-19-0413
Volume/Issue:
Volume 245: Issue 1
Open access
A Cremades
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C Ruzafa
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F Monserrat
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A J López-Contreras
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R Peñafiel
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arginine in plasma and tissues that almost abolished the sexual dimorphism found in the levels of this amino acid. This dietary restriction also affected the activities of enzymes related to the metabolism of arginine and ornithine that are regulated by sex

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.05783
Volume/Issue:
Volume 183: Issue 2
Free access
Alan Conley Department of Population Health & Reproduction, School of Veterinary Medicine, University of California, Davis, California, USA

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Ned J Place Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA

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Erin L Legacki Department of Population Health & Reproduction, School of Veterinary Medicine, University of California, Davis, California, USA

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Geoff L Hammond Department of Cellular & Physiological Sciences, University of British Columbia, Vancouver, British Columbia, Canada

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Gerald R Cunha Department of Urology, University of California, San Francisco, California, USA

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Christine M Drea Departments of Evolutionary Anthropology and Biology, Duke University, Durham, North Carolina, USA

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Mary L Weldele Departments of Psychology and Integrative Biology, University of California, Berkeley, California, USA

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Steve E Glickman Departments of Psychology and Integrative Biology, University of California, Berkeley, California, USA

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deviance from gender norms’ ( Wilson 2003 ). Spotted hyaenas have thus fascinated biologists in the degree to which they deviate from a binary view of sexual dimorphism in mammals, exhibiting a behavioural repertoire (including pronounced aggression, social

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-20-0252
Volume/Issue:
Volume 247: Issue 1
Free access
Lydie Naulé Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224
Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224
Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224

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Marie Picot Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224
Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224
Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224

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Mariangela Martini Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224
Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224
Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224

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Caroline Parmentier Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224
Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224
Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224

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Hélène Hardin-Pouzet Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224
Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224
Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224

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Matthieu Keller Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224
Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224
Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224

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Isabelle Franceschini Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224
Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224
Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224

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Sakina Mhaouty-Kodja Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224
Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224
Sorbonne Universités, Centre National de la Recherche Scientifique (CNRS) UMR 7224, Institut National de la Recherche Agronomique (INRA) UMR85, CNRS UMR 7247, Université François Rabelais, UPMC University Paris 06, UMR 7224

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J Herbison AE 2006 Postnatal development of kisspeptin neurons in mouse hypothalamus; sexual dimorphism and projections to gonadotropin-releasing hormone neurons . Endocrinology 147 5817 – 5825 . ( doi:10.1210/en.2006-0787 ) Clarkson J

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0607
Volume/Issue:
Volume 220: Issue 3
Free access
Rajat K Das
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Sarmistha Banerjee
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Bernard H Shapiro Department of Biomedical Sciences, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, Pennsylvania, USA

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permanently alter some functional aspect normally responsive to the hormone and often establishing a sexual dimorphism ( Csaba 2008 ). Moreover, the tissue is programmable for only a brief developmental period, after which time the tissue becomes permanently

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-16-0471
Volume/Issue:
Volume 232: Issue 3
Free access
Rebecca J Ainslie Institute for Regeneration and Repair, the University of Edinburgh, Edinburgh BioQuarter, Edinburgh, United Kingdom

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Ioannis Simitsidellis Institute for Regeneration and Repair, the University of Edinburgh, Edinburgh BioQuarter, Edinburgh, United Kingdom

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Phoebe M Kirkwood Institute for Regeneration and Repair, the University of Edinburgh, Edinburgh BioQuarter, Edinburgh, United Kingdom

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Douglas A Gibson Institute for Regeneration and Repair, the University of Edinburgh, Edinburgh BioQuarter, Edinburgh, United Kingdom

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assessment of isolated populations or deduced from cohort differences due to sex or suppression of endogenous hormones. It is well known that sexual dimorphism in immune responses affects the prevalence and severity of a range of inflammatory conditions, but

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-23-0398
Volume/Issue:
Volume 261: Issue 3
Open access
Gerard Karsenty Department of Genetics and Development, Columbia University, HHSC 701 West 168th Street, HHSC1602, New York, New York 10032, USA

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sexual dimorphism in bone growth becomes apparent during puberty, at which time men reach higher peak bone mass ( Clarke & Khosla 2010 ). This skeletal sexual dimorphism is mainly due to a stimulatory androgen action on periosteal bone formation in men

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-11-0452
Volume/Issue:
Volume 213: Issue 2
Free access
Caroline Alfaia PRC, INRA, CNRS, IFCE, Tours University, Nouzilly, France

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Vincent Robert PRC, INRA, CNRS, IFCE, Tours University, Nouzilly, France

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Kevin Poissenot PRC, INRA, CNRS, IFCE, Tours University, Nouzilly, France

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Yves Levern ISP, INRA, Tours University, Nouzilly, France

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Daniel Guillaume PRC, INRA, CNRS, IFCE, Tours University, Nouzilly, France

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Shel-Hwa Yeo Reproductive Physiology Group, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK

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William H Colledge Reproductive Physiology Group, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK

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Isabelle Franceschini PRC, INRA, CNRS, IFCE, Tours University, Nouzilly, France

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study, we hypothesized that the sexual dimorphism of Kiss1 neurons in the ARC starts to develop before birth. It was recently shown that Kiss1 expression in the ARC is turned on very early in the fetal brain ( Desroziers et al. 2012 , Knoll et al

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0142
Volume/Issue:
Volume 244: Issue 2
Restricted access
Iris Boraschi-Diaz Shriners Hospital for Children-Canada, Montreal, Quebec, Canada
Faculty of Dentistry, McGill University, Montreal, Quebec, Canada

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Josephine T Tauer Shriners Hospital for Children-Canada, Montreal, Quebec, Canada

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Omar El-Rifai Unité de Recherche en Physiologie Intégrative et Moléculaire, Institut de Recherches Cliniques de Montréal, Montréal, Québec, Canada

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Delphine Guillemette Shriners Hospital for Children-Canada, Montreal, Quebec, Canada
Département de Mathématiques, Université du Québec à Montréal, Montréal, Québec, Canada

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Geneviève Lefebvre Département de Mathématiques, Université du Québec à Montréal, Montréal, Québec, Canada

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Frank Rauch Shriners Hospital for Children-Canada, Montreal, Quebec, Canada

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Mathieu Ferron Unité de Recherche en Physiologie Intégrative et Moléculaire, Institut de Recherches Cliniques de Montréal, Montréal, Québec, Canada
Départements de Médecine et de Biochimie et Médecine Moléculaire, Université de Montréal, Montréal, Québec, Canada

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Svetlana V Komarova Shriners Hospital for Children-Canada, Montreal, Quebec, Canada
Faculty of Dentistry, McGill University, Montreal, Quebec, Canada

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the effect of genotype over time. Student t -test was used to compare between two groups at a single time point. Three-way ANOVA was used to examine sexual dimorphism. Statistical analyses were performed using MATLAB (The MathWorks Inc

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-17-0335
Volume/Issue:
Volume 234: Issue 3
Free access