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Anne-Marie Neumann Institute of Neurobiology, University of Lübeck, Lübeck, Germany
Center of Brain, Behavior and Metabolism, University of Lübeck, Lübeck, Germany

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Cathleen Geißler Center of Brain, Behavior and Metabolism, University of Lübeck, Lübeck, Germany
Institute for Human Genetics, Epigenetics and Metabolism Lab, University of Lübeck, Lübeck, Germany

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Violetta Pilorz Institute of Neurobiology, University of Lübeck, Lübeck, Germany
Center of Brain, Behavior and Metabolism, University of Lübeck, Lübeck, Germany

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Iwona Olejniczak Institute of Neurobiology, University of Lübeck, Lübeck, Germany
Center of Brain, Behavior and Metabolism, University of Lübeck, Lübeck, Germany

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Alfor G Lewis Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA

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Randy J Seeley Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA

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Orr Shomroni Transcriptome and Genome Analysis Core Unit, University Medical Center Göttingen, Göttingen, Germany

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Gabriela Salinas-Riester Transcriptome and Genome Analysis Core Unit, University Medical Center Göttingen, Göttingen, Germany

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Henriette Kirchner Center of Brain, Behavior and Metabolism, University of Lübeck, Lübeck, Germany
Institute for Human Genetics, Epigenetics and Metabolism Lab, University of Lübeck, Lübeck, Germany
German Center for Diabetes Research (DZD), Helmholtz Zentrum München, Bayern, Germany

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Henrik Oster Institute of Neurobiology, University of Lübeck, Lübeck, Germany
Center of Brain, Behavior and Metabolism, University of Lübeck, Lübeck, Germany

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-circadian regulation in a highly specific manner suggesting that circadian network reorganization may affect the metabolic success of bariatric surgical interventions. Methods Animal experiments (short) Animal experiments were conducted in accordance with

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-20-0611
Volume/Issue:
Volume 250: Issue 2
Restricted access
C E Koch University of Lübeck, Chronophysiology Group, Medical Department 1, Lübeck, Germany

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M S Bartlang University of Würzburg, Biocenter, Theodor-Boveri-Institute, Neurobiology and Genetics, Würzburg, Germany

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J T Kiehn University of Lübeck, Chronophysiology Group, Medical Department 1, Lübeck, Germany

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L Lucke Department of Behavioral and Molecular Neurobiology, University of Regensburg, Regensburg, Germany

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N Naujokat University of Lübeck, Chronophysiology Group, Medical Department 1, Lübeck, Germany

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C Helfrich-Förster University of Würzburg, Biocenter, Theodor-Boveri-Institute, Neurobiology and Genetics, Würzburg, Germany

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S O Reber Department of Behavioral and Molecular Neurobiology, University of Regensburg, Regensburg, Germany

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H Oster University of Lübeck, Chronophysiology Group, Medical Department 1, Lübeck, Germany

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rats that mild chronic subordination leads to reduced activity, altered sleeping patterns and increased body temperature, which suggests an increased metabolic rate as response to SDL ( Ahnaou & Drinkenburg 2016 ), which is also reported in squirrels

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-16-0163
Volume/Issue:
Volume 231: Issue 3
Free access
C García-Luna Department of Neurosciences Research, Molecular Neurophysiology Laboratory, National Institute of Psychiatry Ramón de la Fuente Muñiz, Mexico City, Mexico

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P Soberanes-Chávez Department of Neurosciences Research, Molecular Neurophysiology Laboratory, National Institute of Psychiatry Ramón de la Fuente Muñiz, Mexico City, Mexico

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P de Gortari Department of Neurosciences Research, Molecular Neurophysiology Laboratory, National Institute of Psychiatry Ramón de la Fuente Muñiz, Mexico City, Mexico

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the light phase induces leptin and insulin release in an unusual circadian time, with a consequent activation of brain peptides’ synthesis that leads to an aberrant control of energy homeostasis. Prepuberal darkness-phase feeding, which had a short

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-16-0402
Volume/Issue:
Volume 232: Issue 1
Free access
Yan Zhou Laboratory of the Biology of Addictive Diseases, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA

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Jacob Bendor Laboratory of the Biology of Addictive Diseases, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA

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Lauren Hofmann Laboratory of the Biology of Addictive Diseases, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA

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Matthew Randesi Laboratory of the Biology of Addictive Diseases, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA

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Ann Ho Laboratory of the Biology of Addictive Diseases, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA

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Mary Jeanne Kreek Laboratory of the Biology of Addictive Diseases, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA

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). It has been established that the hypothalamic orexins (orexins A and B) are involved in the regulation of sleep, arousal, feeding, and stress ( Saper et al. 2005 , Winsky-Sommerer et al. 2005 ). There is a growing body of evidence suggesting a

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06960
Volume/Issue:
Volume 191: Issue 1
Free access
Junie Hurette Chansi Kengni Groupe de Recherche en Biopathologies Cellulaires et Moléculaires, Département de Chimie-Biologie, Université du Québec à Trois-Rivières, CP 500, Trois-Rivières, Québec, G9A 5H7 Canada

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Isabelle St-Louis Groupe de Recherche en Biopathologies Cellulaires et Moléculaires, Département de Chimie-Biologie, Université du Québec à Trois-Rivières, CP 500, Trois-Rivières, Québec, G9A 5H7 Canada

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Sophie Parent Groupe de Recherche en Biopathologies Cellulaires et Moléculaires, Département de Chimie-Biologie, Université du Québec à Trois-Rivières, CP 500, Trois-Rivières, Québec, G9A 5H7 Canada

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Valérie Leblanc Groupe de Recherche en Biopathologies Cellulaires et Moléculaires, Département de Chimie-Biologie, Université du Québec à Trois-Rivières, CP 500, Trois-Rivières, Québec, G9A 5H7 Canada

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Carl Shooner Groupe de Recherche en Biopathologies Cellulaires et Moléculaires, Département de Chimie-Biologie, Université du Québec à Trois-Rivières, CP 500, Trois-Rivières, Québec, G9A 5H7 Canada

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Eric Asselin Groupe de Recherche en Biopathologies Cellulaires et Moléculaires, Département de Chimie-Biologie, Université du Québec à Trois-Rivières, CP 500, Trois-Rivières, Québec, G9A 5H7 Canada

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). Decidualization can be initiated only when the endometrium is receptive, and this only occurs during a short period in pregnancy. Several decades of investigations have showed that PGs are needed to trigger the events of blastocyst implantation. Implantation

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-07-0353
Volume/Issue:
Volume 195: Issue 2
Free access
J E Digby Warwick Medical School, Clinical Sciences Research Institute, University of Warwick, Gibbett Hill Road, Coventry CV4 7AL, UK
Department of Biological Sciences, Biomedical Research Institute, University of Warwick, Gibbett Hill Road, Coventry CV4 7AL, UK
Warwickshire Nuffield Hospital, Leamington Spa, Warwickshire, CV32 6RW, UK

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J Chen Warwick Medical School, Clinical Sciences Research Institute, University of Warwick, Gibbett Hill Road, Coventry CV4 7AL, UK
Department of Biological Sciences, Biomedical Research Institute, University of Warwick, Gibbett Hill Road, Coventry CV4 7AL, UK
Warwickshire Nuffield Hospital, Leamington Spa, Warwickshire, CV32 6RW, UK

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J Y Tang Warwick Medical School, Clinical Sciences Research Institute, University of Warwick, Gibbett Hill Road, Coventry CV4 7AL, UK
Department of Biological Sciences, Biomedical Research Institute, University of Warwick, Gibbett Hill Road, Coventry CV4 7AL, UK
Warwickshire Nuffield Hospital, Leamington Spa, Warwickshire, CV32 6RW, UK

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H Lehnert Warwick Medical School, Clinical Sciences Research Institute, University of Warwick, Gibbett Hill Road, Coventry CV4 7AL, UK
Department of Biological Sciences, Biomedical Research Institute, University of Warwick, Gibbett Hill Road, Coventry CV4 7AL, UK
Warwickshire Nuffield Hospital, Leamington Spa, Warwickshire, CV32 6RW, UK

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R N Matthews Warwick Medical School, Clinical Sciences Research Institute, University of Warwick, Gibbett Hill Road, Coventry CV4 7AL, UK
Department of Biological Sciences, Biomedical Research Institute, University of Warwick, Gibbett Hill Road, Coventry CV4 7AL, UK
Warwickshire Nuffield Hospital, Leamington Spa, Warwickshire, CV32 6RW, UK

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H S Randeva Warwick Medical School, Clinical Sciences Research Institute, University of Warwick, Gibbett Hill Road, Coventry CV4 7AL, UK
Department of Biological Sciences, Biomedical Research Institute, University of Warwick, Gibbett Hill Road, Coventry CV4 7AL, UK
Warwickshire Nuffield Hospital, Leamington Spa, Warwickshire, CV32 6RW, UK

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into the central nervous system, resulting in multiple physiological functions, including the control of arousal and sleep–wake cycle, regulation of cardiovascular and autonomic function, and the neuroendocrine system ( Ida et al. 1999 , Samson et

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06886
Volume/Issue:
Volume 191: Issue 1
Free access
Harleen Kaur Robinson Research Institute, University of Adelaide, Adelaide, Australia
Adelaide Medical School, University of Adelaide, Adelaide, Australia

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Beverly S Muhlhausler CSIRO Nutrition and Health, Adelaide, Australia

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Claire T Roberts Robinson Research Institute, University of Adelaide, Adelaide, Australia
Adelaide Medical School, University of Adelaide, Adelaide, Australia
College of Medicine and Public Health, Flinders University, Bedford Park, South Australia, Australia
College of Medicine and Public Health, Flinders University, Bedford Park, South Australia, Australia

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Kathryn L Gatford Robinson Research Institute, University of Adelaide, Adelaide, Australia
Adelaide Medical School, University of Adelaide, Adelaide, Australia

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concentrations of sex steroids (puberty, sex), age, sleep, exercise, stress, insulin, glucose, amino acids and fatty acid concentrations, visceral fat mass and pregnancy, the latter discussed in detail later in this review ( Veldhuis et al. 2006 ). Figure 1

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-21-0087
Volume/Issue:
Volume 251: Issue 3
Free access
S R Davis Department of Medicine (CECS), Monash University, Victoria, Australia
The Jean Hailes Foundation, 173 Carinish Road, Clayton, Victoria, Australia
Department of Biochemistry, Monash University, Clayton, Victoria, Australia

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I Dinatale Department of Medicine (CECS), Monash University, Victoria, Australia
The Jean Hailes Foundation, 173 Carinish Road, Clayton, Victoria, Australia
Department of Biochemistry, Monash University, Clayton, Victoria, Australia

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L Rivera-Woll Department of Medicine (CECS), Monash University, Victoria, Australia
The Jean Hailes Foundation, 173 Carinish Road, Clayton, Victoria, Australia
Department of Biochemistry, Monash University, Clayton, Victoria, Australia

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S Davison Department of Medicine (CECS), Monash University, Victoria, Australia
The Jean Hailes Foundation, 173 Carinish Road, Clayton, Victoria, Australia
Department of Biochemistry, Monash University, Clayton, Victoria, Australia

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Introduction Life expectancy has increased dramatically over the course of history, such that in contrast to earlier times, when the average life span was quite short, we are now in an era where we expect to grow old. In 1000 bc

Article Type:
Other
DOI:
https://doi.org/10.1677/joe.1.05847
Volume/Issue:
Volume 185: Issue 2
Free access
Bernard Khoo Endocrinology, Division of Medicine, University College London, Royal Free Campus, London, UK

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Tricia Mei-Mei Tan Department of Digestion, Metabolism and Reproduction, Imperial College London, Hammersmith Campus, London, UK

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, type 2 diabetes (T2D), hypertension, hyperlipidaemia, obstructive sleep apnoea, subfertility, cancers (breast, ovary, prostate, liver, endometrium and colon) and fatty liver disease/steatohepatitis leading to cirrhosis and liver failure. Key drivers of

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-20-0119
Volume/Issue:
Volume 246: Issue 3
Free access
Rita Sharma Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA
The Diabetes Institute, Ohio University, Athens, Ohio, USA

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Quyen Luong Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA
The Diabetes Institute, Ohio University, Athens, Ohio, USA

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Vishva M Sharma Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA
The Diabetes Institute, Ohio University, Athens, Ohio, USA

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Mitchell Harberson Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA
The Diabetes Institute, Ohio University, Athens, Ohio, USA

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Brian Harper Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA
The Diabetes Institute, Ohio University, Athens, Ohio, USA

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Andrew Colborn Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA
The Diabetes Institute, Ohio University, Athens, Ohio, USA

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Darlene E Berryman Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA
The Diabetes Institute, Ohio University, Athens, Ohio, USA

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Niels Jessen Research Laboratory for Biochemical Pathology, Aarhus University Hospital, Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Biomedicine, Aarhus University, Aarhus, Denmark

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Jens Otto Lunde Jørgensen Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Medical Research Laboratory, Aarhus University, Aarhus, Denmark

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John J Kopchick Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA
The Diabetes Institute, Ohio University, Athens, Ohio, USA
Edison Biotechnology Institute, Ohio University, Athens, Ohio, USA

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Vishwajeet Puri Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA
The Diabetes Institute, Ohio University, Athens, Ohio, USA

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Kevin Y Lee Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA
The Diabetes Institute, Ohio University, Athens, Ohio, USA

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expression of FSP27 is reduced 2 h after GH treatment ( Fig. 1B and C ). Since FSP27 protein is very unstable and has a short half-life of ~15 min ( Nian et al. 2010 , Yang et al. 2011 ), our data indicate that the reduced PPARγ-dependent transcription

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0282
Volume/Issue:
Volume 239: Issue 3
Restricted access