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Mina Elahy
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Swati Baindur-Hudson
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Vinicius F Cruzat College of Health and Biomedicine, School of Biomedical Sciences, Biosciences Research Precinct, School of Pharmacy, Victoria University, St Albans, Victoria 3021, Australia
College of Health and Biomedicine, School of Biomedical Sciences, Biosciences Research Precinct, School of Pharmacy, Victoria University, St Albans, Victoria 3021, Australia

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Philip Newsholme College of Health and Biomedicine, School of Biomedical Sciences, Biosciences Research Precinct, School of Pharmacy, Victoria University, St Albans, Victoria 3021, Australia
College of Health and Biomedicine, School of Biomedical Sciences, Biosciences Research Precinct, School of Pharmacy, Victoria University, St Albans, Victoria 3021, Australia

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Crispin R Dass College of Health and Biomedicine, School of Biomedical Sciences, Biosciences Research Precinct, School of Pharmacy, Victoria University, St Albans, Victoria 3021, Australia
College of Health and Biomedicine, School of Biomedical Sciences, Biosciences Research Precinct, School of Pharmacy, Victoria University, St Albans, Victoria 3021, Australia

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expression of chemical mediators, such as vascular endothelial growth factor (VEGF), tumor necrosis factor alpha (TNFα), and intercellular adhesion molecule 1 (ICAM1) in retinal vascular ECs ( Zhang et al . 2008 , 2011 ). Recent advances in molecular and

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-14-0065
Volume/Issue:
Volume 222: Issue 3
Free access
Yingxin Xian Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Zonglan Chen Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Hongrong Deng Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Mengyin Cai Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Hua Liang Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Wen Xu Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Jianping Weng Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Fen Xu Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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′-GATGAGTTCTGAACGTCGAAAAGAAAAGT-3′ Hif-1a R 5′-GAAGTTTTCTCACACGTAAATAACTGATGGTG-3′ Vegf F 5′-GAGCAGAAGTCCCATGAAGTGA-3′ Vegf R 5′-CACAGGA CGGCTTGAAGATGT-3′ Vegfr2 F 5′-GCTCCGCCCCCAACTCCT-3′ Vegfr2 R 5′-CTCATAGCCCGCATCCTCCACA-3

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0639
Volume/Issue:
Volume 242: Issue 2
Free access
D S Boeldt Perinatal Research Laboratories, Department of Obstetrics and Gynecology, University of Wisconsin‐Madison, 7E Meriter Hospital/Park, 202 South Park Street, Madison, Wisconsin 53715, USA

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F X Yi Perinatal Research Laboratories, Department of Obstetrics and Gynecology, University of Wisconsin‐Madison, 7E Meriter Hospital/Park, 202 South Park Street, Madison, Wisconsin 53715, USA

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I M Bird Perinatal Research Laboratories, Department of Obstetrics and Gynecology, University of Wisconsin‐Madison, 7E Meriter Hospital/Park, 202 South Park Street, Madison, Wisconsin 53715, USA

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agonist and pregnancy sensitive interaction between IP3R2 and TRPC3, such that ATP but not vascular endothelial growth factor (VEGF-165) stimulated significant interaction in P-UAEC but not NP-UAEC. Furthermore, at 19 min post-stimulation, a time where the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-11-0053
Volume/Issue:
Volume 210: Issue 3
Free access
Yang Chen Transgenic Research Center, Northeast Normal University, Changchun, China

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Mingyue Zhao Transgenic Research Center, Northeast Normal University, Changchun, China

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Chenhao Wang Transgenic Research Center, Northeast Normal University, Changchun, China

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Huaizhen Wen Transgenic Research Center, Northeast Normal University, Changchun, China

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Yuntao Zhang Transgenic Research Center, Northeast Normal University, Changchun, China

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Mingxu Lu Transgenic Research Center, Northeast Normal University, Changchun, China

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Salah Adlat Transgenic Research Center, Northeast Normal University, Changchun, China

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Tingting Zheng Transgenic Research Center, Northeast Normal University, Changchun, China

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Mingjiao Zhang Transgenic Research Center, Northeast Normal University, Changchun, China

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Dan Li Transgenic Research Center, Northeast Normal University, Changchun, China

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Xiaodan Lu Transgenic Research Center, Northeast Normal University, Changchun, China

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Mengwei Guo Transgenic Research Center, Northeast Normal University, Changchun, China

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Hongyu Chen Transgenic Research Center, Northeast Normal University, Changchun, China

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Luqing Zhang Transgenic Research Center, Northeast Normal University, Changchun, China
Key Laboratory of Molecular Epigenetics of Ministry of Education, Northeast Normal University, Changchun, China

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Xuechao Feng Transgenic Research Center, Northeast Normal University, Changchun, China
Key Laboratory of Molecular Epigenetics of Ministry of Education, Northeast Normal University, Changchun, China

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Yaowu Zheng Transgenic Research Center, Northeast Normal University, Changchun, China
Key Laboratory of Molecular Epigenetics of Ministry of Education, Northeast Normal University, Changchun, China

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organ in form of triglycerides. At the same time, WAT is an important secretory organ and produces leptin, adiponectin, resistin and growth factors including vascular endothelial growth factors (VEGFs) ( Mick et al . 2002 , Fain et al . 2004

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-19-0341
Volume/Issue:
Volume 244: Issue 3
Restricted access
Hsiu-Chi Lee Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan

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Shaw-Jenq Tsai Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan
Department of Physiology, College of Medicine, National Cheng Kung University, Tainan, Taiwan

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-activator in the nucleus. The heterodimer of HIF binds to consensus sequence HRE at the promoter region of HIF-responsive genes, such as VEGF and EPO , and initiates the gene transcription. Besides hydroxylation at the proline residues, HIF-α also

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-16-0653
Volume/Issue:
Volume 234: Issue 1
Free access
Kai Wang
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Jing Zheng Clinical and Translational Research Center, Perinatal Research Laboratories, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 200040, China

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that the VEGF/FGF2-NO reciprocal regulation may not occur within placental endothelia, although such regulation may exist between placental vascular endothelia and smooth muscle cells. It is noteworthy that this discrepancy in such NO regulation could

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-11-0296
Volume/Issue:
Volume 212: Issue 3
Free access
Soo-Hyun Kim
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Jeremy Turnbull Division of Biomedical Sciences, Institute of Integrative Biology, St George's Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK

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Scott Guimond Division of Biomedical Sciences, Institute of Integrative Biology, St George's Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK

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developmental processes ( Kirkpatrick et al . 2004 , Kreuger et al . 2004 ). Such examples include fibroblast growth factors (FGFs) and vascular endothelial growth factors (VEGFs), both of which bind to HSPG and can be cleaved off from the glycosaminoglycan

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-10-0377
Volume/Issue:
Volume 209: Issue 2
Free access
Alison E Wallace MRC Human Reproductive Sciences Unit, The Queen's Medical Research Institute, Centre for Reproductive Biology, 47 Little France Crescent, Edinburgh EH16 4TJ, UK

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Douglas A Gibson MRC Human Reproductive Sciences Unit, The Queen's Medical Research Institute, Centre for Reproductive Biology, 47 Little France Crescent, Edinburgh EH16 4TJ, UK

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Philippa T K Saunders MRC Human Reproductive Sciences Unit, The Queen's Medical Research Institute, Centre for Reproductive Biology, 47 Little France Crescent, Edinburgh EH16 4TJ, UK

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Henry N Jabbour MRC Human Reproductive Sciences Unit, The Queen's Medical Research Institute, Centre for Reproductive Biology, 47 Little France Crescent, Edinburgh EH16 4TJ, UK

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production occurs before the re-growth of tissue mediated by growth factors such as epidermal growth factor (EGF) and platelet-derived growth factor. Angiogenesis is mediated by local mediators including vascular endothelial growth factor (VEGF) and

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-10-0072
Volume/Issue:
Volume 206: Issue 2
Free access
Kyle Caires Department of Animal Sciences, Center for Reproductive Biology, Washington State University, PO Box 646353, Pullman, Washington 99164-6353, USA

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Johnathan Broady Department of Animal Sciences, Center for Reproductive Biology, Washington State University, PO Box 646353, Pullman, Washington 99164-6353, USA

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Derek McLean Department of Animal Sciences, Center for Reproductive Biology, Washington State University, PO Box 646353, Pullman, Washington 99164-6353, USA

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activation of several signaling cascades by GDNF binding to GFRα1 and RET raises the possibility that crosstalk between signaling pathways may regulate SSCs. For example, in the developing kidney, crosstalk between vascular endothelial growth factor (VEGF

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-09-0275
Volume/Issue:
Volume 205: Issue 2
Free access
Verónica Torres-Estay Departamento de Fisiología, Urología, Center for Integrative Medicine and Innovative Sciences, Department of Urology, Pontificia Universidad Católica de Chile, Santiago de Chile, Chile

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Daniela V Carreño Departamento de Fisiología, Urología, Center for Integrative Medicine and Innovative Sciences, Department of Urology, Pontificia Universidad Católica de Chile, Santiago de Chile, Chile

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Ignacio F San Francisco Departamento de Fisiología, Urología, Center for Integrative Medicine and Innovative Sciences, Department of Urology, Pontificia Universidad Católica de Chile, Santiago de Chile, Chile

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Paula Sotomayor Departamento de Fisiología, Urología, Center for Integrative Medicine and Innovative Sciences, Department of Urology, Pontificia Universidad Católica de Chile, Santiago de Chile, Chile

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Alejandro S Godoy Departamento de Fisiología, Urología, Center for Integrative Medicine and Innovative Sciences, Department of Urology, Pontificia Universidad Católica de Chile, Santiago de Chile, Chile
Departamento de Fisiología, Urología, Center for Integrative Medicine and Innovative Sciences, Department of Urology, Pontificia Universidad Católica de Chile, Santiago de Chile, Chile

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Gary J Smith Departamento de Fisiología, Urología, Center for Integrative Medicine and Innovative Sciences, Department of Urology, Pontificia Universidad Católica de Chile, Santiago de Chile, Chile

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through upregulation of the expression of VEGF-A, cyclin A, and cyclin D1. The stimulation of EC proliferation in the cardiovascular system by activation of AR could contribute to the repair of EC injury/damage, and prevent EC dysfunction, minimizing a

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-14-0611
Volume/Issue:
Volume 224: Issue 3
Free access