Search Results

You are looking at 61 - 70 of 757 items for :

  • "adaptation" x
  • Refine by access: All content x
Clear All
B T Layden
Search for other papers by B T Layden in
Google Scholar
PubMed
Close
,
V Durai
Search for other papers by V Durai in
Google Scholar
PubMed
Close
,
M V Newman
Search for other papers by M V Newman in
Google Scholar
PubMed
Close
,
A M Marinelarena
Search for other papers by A M Marinelarena in
Google Scholar
PubMed
Close
,
C W Ahn
Search for other papers by C W Ahn in
Google Scholar
PubMed
Close
,
G Feng Division of Endocrinology, Northwestern University Biomedical Informatics Center, Division of Transplantation Surgery, Genomics Core, Medical Biotechnology Center, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Tarry 15, Chicago, Illinois 60611, USA

Search for other papers by G Feng in
Google Scholar
PubMed
Close
,
S Lin Division of Endocrinology, Northwestern University Biomedical Informatics Center, Division of Transplantation Surgery, Genomics Core, Medical Biotechnology Center, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Tarry 15, Chicago, Illinois 60611, USA

Search for other papers by S Lin in
Google Scholar
PubMed
Close
,
X Zhang Division of Endocrinology, Northwestern University Biomedical Informatics Center, Division of Transplantation Surgery, Genomics Core, Medical Biotechnology Center, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Tarry 15, Chicago, Illinois 60611, USA

Search for other papers by X Zhang in
Google Scholar
PubMed
Close
,
D B Kaufman Division of Endocrinology, Northwestern University Biomedical Informatics Center, Division of Transplantation Surgery, Genomics Core, Medical Biotechnology Center, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Tarry 15, Chicago, Illinois 60611, USA

Search for other papers by D B Kaufman in
Google Scholar
PubMed
Close
,
N Jafari Division of Endocrinology, Northwestern University Biomedical Informatics Center, Division of Transplantation Surgery, Genomics Core, Medical Biotechnology Center, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Tarry 15, Chicago, Illinois 60611, USA

Search for other papers by N Jafari in
Google Scholar
PubMed
Close
,
G L Sørensen Division of Endocrinology, Northwestern University Biomedical Informatics Center, Division of Transplantation Surgery, Genomics Core, Medical Biotechnology Center, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Tarry 15, Chicago, Illinois 60611, USA

Search for other papers by G L Sørensen in
Google Scholar
PubMed
Close
, and
W L Lowe Jr
Search for other papers by W L Lowe Jr in
Google Scholar
PubMed
Close

resistant states of pregnancy and obesity ( Butler et al . 2007 ). Studying states in which insulin needs change can provide insight into pathways mediating β cell adaptations. In mice, β cell mass increases about twofold during pregnancy, with a maximum

Free access
Ferran Jardí Clinical and Experimental Endocrinology, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Leuven, Belgium

Search for other papers by Ferran Jardí in
Google Scholar
PubMed
Close
,
Michaël R Laurent Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
Gerontology and Geriatrics, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Leuven, Belgium

Search for other papers by Michaël R Laurent in
Google Scholar
PubMed
Close
,
Vanessa Dubois Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium

Search for other papers by Vanessa Dubois in
Google Scholar
PubMed
Close
,
Nari Kim Clinical and Experimental Endocrinology, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Leuven, Belgium

Search for other papers by Nari Kim in
Google Scholar
PubMed
Close
,
Rougin Khalil Clinical and Experimental Endocrinology, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Leuven, Belgium

Search for other papers by Rougin Khalil in
Google Scholar
PubMed
Close
,
Brigitte Decallonne Clinical and Experimental Endocrinology, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Leuven, Belgium

Search for other papers by Brigitte Decallonne in
Google Scholar
PubMed
Close
,
Dirk Vanderschueren Clinical and Experimental Endocrinology, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Leuven, Belgium

Search for other papers by Dirk Vanderschueren in
Google Scholar
PubMed
Close
, and
Frank Claessens Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium

Search for other papers by Frank Claessens in
Google Scholar
PubMed
Close

muscle and we have previously reviewed the cellular targets and molecular pathways implicated ( Dubois et al. 2012 ). Therefore, it is conceivable that testosterone increases activity in males by favoring adaptation to exercise (peripheral mechanisms

Free access
Mariana Rosolen Tavares Department of Physiology and Biophysics, Instituto de Ciencias Biomedicas, Universidade de Sao Paulo, Sao Paulo, Brazil

Search for other papers by Mariana Rosolen Tavares in
Google Scholar
PubMed
Close
,
Renata Frazao Department of Anatomy, Instituto de Ciencias Biomedicas, Universidade de Sao Paulo, Sao Paulo, Brazil

Search for other papers by Renata Frazao in
Google Scholar
PubMed
Close
, and
Jose Donato Jr Department of Physiology and Biophysics, Instituto de Ciencias Biomedicas, Universidade de Sao Paulo, Sao Paulo, Brazil

Search for other papers by Jose Donato Jr in
Google Scholar
PubMed
Close

condition that requires numerous metabolic adaptations to the increasing energy demands of the fetus(es). In the present review, we summarize the metabolic effects of GH in the context of situations of stress. Our objective is to postulate that the different

Free access
Dóra Zelena
Search for other papers by Dóra Zelena in
Google Scholar
PubMed
Close
,
Ágnes Domokos
Search for other papers by Ágnes Domokos in
Google Scholar
PubMed
Close
,
Subodh Kumar Jain Institute of Experimental Medicine, Department of Zoology and Biotechnology, Department of Pyschiatry, Pavlov Institute of Physiology, Hungarian Academy of Science, PO Box 67, H-1450 Budapest, Hungary

Search for other papers by Subodh Kumar Jain in
Google Scholar
PubMed
Close
,
Ryan Jankord Institute of Experimental Medicine, Department of Zoology and Biotechnology, Department of Pyschiatry, Pavlov Institute of Physiology, Hungarian Academy of Science, PO Box 67, H-1450 Budapest, Hungary

Search for other papers by Ryan Jankord in
Google Scholar
PubMed
Close
, and
Ludmila Filaretova Institute of Experimental Medicine, Department of Zoology and Biotechnology, Department of Pyschiatry, Pavlov Institute of Physiology, Hungarian Academy of Science, PO Box 67, H-1450 Budapest, Hungary

Search for other papers by Ludmila Filaretova in
Google Scholar
PubMed
Close

for adaptation ( Selye 1937 ). At the time of his discovery, the central regulating molecules of the HPA axis were not established. Following its identification in 1954, arginine vasopressin (AVP) was considered as the principal regulator of ACTH

Free access
Caitlin S Wyrwoll School of Human Sciences, University of Western Australia, Crawley, Western Australia, Australia
Telethon Kids Institute, Perth, Australia
Healthy Environments and Lives (HEAL) Network

Search for other papers by Caitlin S Wyrwoll in
Google Scholar
PubMed
Close

ramifications for offspring health in later life. Her recent research focuses on the environmental change (particularly heat exposure and drinking water quality) on maternal adaptations to pregnancy and child health outcomes. This work is becoming increasingly

Free access
M A Hyatt Institute of Clinical Research, Centre for Reproduction and Early Life,
Children’s Brain Tumour Research Centre,
School of Nursing, The University of Nottingham, Nottingham NG7 2UH, UK
Macaulay Institute, Craigiebuckler, Aberdeen AB15 8QH, UK
Astra Zeneca, Alderley Park, Cheshire, UK
Discipline of Physiology, University of Adelaide, Adelaide, South Australia 5005, Australia

Search for other papers by M A Hyatt in
Google Scholar
PubMed
Close
,
G S Gopalakrishnan Institute of Clinical Research, Centre for Reproduction and Early Life,
Children’s Brain Tumour Research Centre,
School of Nursing, The University of Nottingham, Nottingham NG7 2UH, UK
Macaulay Institute, Craigiebuckler, Aberdeen AB15 8QH, UK
Astra Zeneca, Alderley Park, Cheshire, UK
Discipline of Physiology, University of Adelaide, Adelaide, South Australia 5005, Australia

Search for other papers by G S Gopalakrishnan in
Google Scholar
PubMed
Close
,
J Bispham Institute of Clinical Research, Centre for Reproduction and Early Life,
Children’s Brain Tumour Research Centre,
School of Nursing, The University of Nottingham, Nottingham NG7 2UH, UK
Macaulay Institute, Craigiebuckler, Aberdeen AB15 8QH, UK
Astra Zeneca, Alderley Park, Cheshire, UK
Discipline of Physiology, University of Adelaide, Adelaide, South Australia 5005, Australia

Search for other papers by J Bispham in
Google Scholar
PubMed
Close
,
S Gentili Institute of Clinical Research, Centre for Reproduction and Early Life,
Children’s Brain Tumour Research Centre,
School of Nursing, The University of Nottingham, Nottingham NG7 2UH, UK
Macaulay Institute, Craigiebuckler, Aberdeen AB15 8QH, UK
Astra Zeneca, Alderley Park, Cheshire, UK
Discipline of Physiology, University of Adelaide, Adelaide, South Australia 5005, Australia

Search for other papers by S Gentili in
Google Scholar
PubMed
Close
,
I C McMillen Institute of Clinical Research, Centre for Reproduction and Early Life,
Children’s Brain Tumour Research Centre,
School of Nursing, The University of Nottingham, Nottingham NG7 2UH, UK
Macaulay Institute, Craigiebuckler, Aberdeen AB15 8QH, UK
Astra Zeneca, Alderley Park, Cheshire, UK
Discipline of Physiology, University of Adelaide, Adelaide, South Australia 5005, Australia

Search for other papers by I C McMillen in
Google Scholar
PubMed
Close
,
S M Rhind Institute of Clinical Research, Centre for Reproduction and Early Life,
Children’s Brain Tumour Research Centre,
School of Nursing, The University of Nottingham, Nottingham NG7 2UH, UK
Macaulay Institute, Craigiebuckler, Aberdeen AB15 8QH, UK
Astra Zeneca, Alderley Park, Cheshire, UK
Discipline of Physiology, University of Adelaide, Adelaide, South Australia 5005, Australia

Search for other papers by S M Rhind in
Google Scholar
PubMed
Close
,
M T Rae Institute of Clinical Research, Centre for Reproduction and Early Life,
Children’s Brain Tumour Research Centre,
School of Nursing, The University of Nottingham, Nottingham NG7 2UH, UK
Macaulay Institute, Craigiebuckler, Aberdeen AB15 8QH, UK
Astra Zeneca, Alderley Park, Cheshire, UK
Discipline of Physiology, University of Adelaide, Adelaide, South Australia 5005, Australia

Search for other papers by M T Rae in
Google Scholar
PubMed
Close
,
C E Kyle Institute of Clinical Research, Centre for Reproduction and Early Life,
Children’s Brain Tumour Research Centre,
School of Nursing, The University of Nottingham, Nottingham NG7 2UH, UK
Macaulay Institute, Craigiebuckler, Aberdeen AB15 8QH, UK
Astra Zeneca, Alderley Park, Cheshire, UK
Discipline of Physiology, University of Adelaide, Adelaide, South Australia 5005, Australia

Search for other papers by C E Kyle in
Google Scholar
PubMed
Close
,
A N Brooks Institute of Clinical Research, Centre for Reproduction and Early Life,
Children’s Brain Tumour Research Centre,
School of Nursing, The University of Nottingham, Nottingham NG7 2UH, UK
Macaulay Institute, Craigiebuckler, Aberdeen AB15 8QH, UK
Astra Zeneca, Alderley Park, Cheshire, UK
Discipline of Physiology, University of Adelaide, Adelaide, South Australia 5005, Australia

Search for other papers by A N Brooks in
Google Scholar
PubMed
Close
,
C Jones Institute of Clinical Research, Centre for Reproduction and Early Life,
Children’s Brain Tumour Research Centre,
School of Nursing, The University of Nottingham, Nottingham NG7 2UH, UK
Macaulay Institute, Craigiebuckler, Aberdeen AB15 8QH, UK
Astra Zeneca, Alderley Park, Cheshire, UK
Discipline of Physiology, University of Adelaide, Adelaide, South Australia 5005, Australia

Search for other papers by C Jones in
Google Scholar
PubMed
Close
,
H Budge Institute of Clinical Research, Centre for Reproduction and Early Life,
Children’s Brain Tumour Research Centre,
School of Nursing, The University of Nottingham, Nottingham NG7 2UH, UK
Macaulay Institute, Craigiebuckler, Aberdeen AB15 8QH, UK
Astra Zeneca, Alderley Park, Cheshire, UK
Discipline of Physiology, University of Adelaide, Adelaide, South Australia 5005, Australia

Search for other papers by H Budge in
Google Scholar
PubMed
Close
,
D Walker Institute of Clinical Research, Centre for Reproduction and Early Life,
Children’s Brain Tumour Research Centre,
School of Nursing, The University of Nottingham, Nottingham NG7 2UH, UK
Macaulay Institute, Craigiebuckler, Aberdeen AB15 8QH, UK
Astra Zeneca, Alderley Park, Cheshire, UK
Discipline of Physiology, University of Adelaide, Adelaide, South Australia 5005, Australia

Search for other papers by D Walker in
Google Scholar
PubMed
Close
,
T Stephenson Institute of Clinical Research, Centre for Reproduction and Early Life,
Children’s Brain Tumour Research Centre,
School of Nursing, The University of Nottingham, Nottingham NG7 2UH, UK
Macaulay Institute, Craigiebuckler, Aberdeen AB15 8QH, UK
Astra Zeneca, Alderley Park, Cheshire, UK
Discipline of Physiology, University of Adelaide, Adelaide, South Australia 5005, Australia

Search for other papers by T Stephenson in
Google Scholar
PubMed
Close
, and
M E Symonds Institute of Clinical Research, Centre for Reproduction and Early Life,
Children’s Brain Tumour Research Centre,
School of Nursing, The University of Nottingham, Nottingham NG7 2UH, UK
Macaulay Institute, Craigiebuckler, Aberdeen AB15 8QH, UK
Astra Zeneca, Alderley Park, Cheshire, UK
Discipline of Physiology, University of Adelaide, Adelaide, South Australia 5005, Australia

Search for other papers by M E Symonds in
Google Scholar
PubMed
Close

fetal configuration is accompanied by a range of endocrine adaptations including a decrease in plasma insulin-like growth factor (IGF)-I and IGF-II and increased growth hormone (GH) concentration ( Bauer et al. 1995 ). In contrast, maternal nutrient

Free access
Antonia Hufnagel University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Wellcome Trust-MRC Institute of Metabolic Science, Level 4, Addenbrooke’s Hospital, Cambridge, Cambridgeshire, UK

Search for other papers by Antonia Hufnagel in
Google Scholar
PubMed
Close
,
Laura Dearden University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Wellcome Trust-MRC Institute of Metabolic Science, Level 4, Addenbrooke’s Hospital, Cambridge, Cambridgeshire, UK

Search for other papers by Laura Dearden in
Google Scholar
PubMed
Close
,
Denise S Fernandez-Twinn University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Wellcome Trust-MRC Institute of Metabolic Science, Level 4, Addenbrooke’s Hospital, Cambridge, Cambridgeshire, UK

Search for other papers by Denise S Fernandez-Twinn in
Google Scholar
PubMed
Close
, and
Susan E Ozanne University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Wellcome Trust-MRC Institute of Metabolic Science, Level 4, Addenbrooke’s Hospital, Cambridge, Cambridgeshire, UK

Search for other papers by Susan E Ozanne in
Google Scholar
PubMed
Close

gathered current evidence for the effects of maternal and fetal hyperinsulinaemia on developmental programming and describe the direct effects of insulin on the placenta and the maternal metabolic and cardiovascular adaptation to pregnancy. We also discuss

Open access
Swagat Ray Biomedical Sciences Section, School of Biological Sciences, University of Reading, Hopkins Building, Whiteknights, Reading RG6 6UB, UK

Search for other papers by Swagat Ray in
Google Scholar
PubMed
Close
,
Michael J Fry Biomedical Sciences Section, School of Biological Sciences, University of Reading, Hopkins Building, Whiteknights, Reading RG6 6UB, UK

Search for other papers by Michael J Fry in
Google Scholar
PubMed
Close
, and
Philippa D Darbre Biomedical Sciences Section, School of Biological Sciences, University of Reading, Hopkins Building, Whiteknights, Reading RG6 6UB, UK

Search for other papers by Philippa D Darbre in
Google Scholar
PubMed
Close

1987 , Daly & Darbre 1990 a , Jeng et al . 1998 , Shaw et al . 2006 ). The molecular basis for this growth adaptation in MCF-7 cells has been suggested to result from the increased ER levels causing the cells to become hypersensitive to low levels

Free access
Alex Rafacho Department of Physiological Sciences, Department of Clinical Science and Education, Institute of Bioengineering and the Biomedical Research Center in Diabetes and Associated Metabolic Disorders (CIBERDEM), Center of Biological Sciences, Federal University of Santa Catarina (UFSC), 88040-900, Florianópolis, SC, Brazil

Search for other papers by Alex Rafacho in
Google Scholar
PubMed
Close
,
Henrik Ortsäter Department of Physiological Sciences, Department of Clinical Science and Education, Institute of Bioengineering and the Biomedical Research Center in Diabetes and Associated Metabolic Disorders (CIBERDEM), Center of Biological Sciences, Federal University of Santa Catarina (UFSC), 88040-900, Florianópolis, SC, Brazil

Search for other papers by Henrik Ortsäter in
Google Scholar
PubMed
Close
,
Angel Nadal Department of Physiological Sciences, Department of Clinical Science and Education, Institute of Bioengineering and the Biomedical Research Center in Diabetes and Associated Metabolic Disorders (CIBERDEM), Center of Biological Sciences, Federal University of Santa Catarina (UFSC), 88040-900, Florianópolis, SC, Brazil

Search for other papers by Angel Nadal in
Google Scholar
PubMed
Close
, and
Ivan Quesada Department of Physiological Sciences, Department of Clinical Science and Education, Institute of Bioengineering and the Biomedical Research Center in Diabetes and Associated Metabolic Disorders (CIBERDEM), Center of Biological Sciences, Federal University of Santa Catarina (UFSC), 88040-900, Florianópolis, SC, Brazil

Search for other papers by Ivan Quesada in
Google Scholar
PubMed
Close

effects observed in both acute and long-term GC incubation, chronic in vivo administration of these steroids leads to up-regulation of β-cell function as a result of the compensatory adaptation to GC-induced IR. Administration of high doses of

Free access
Dario R Lemos Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of

Search for other papers by Dario R Lemos in
Google Scholar
PubMed
Close
,
Jodi L Downs Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of
Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of
Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of

Search for other papers by Jodi L Downs in
Google Scholar
PubMed
Close
,
Martin N Raitiere Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of

Search for other papers by Martin N Raitiere in
Google Scholar
PubMed
Close
, and
Henryk F Urbanski Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of
Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of
Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of

Search for other papers by Henryk F Urbanski in
Google Scholar
PubMed
Close

adaptation to the seasonal variations that occur in a natural environment throughout the year. It is well established that circadian rhythms are intrinsic to a wide range of body functions, including the sleep–wake cycle, metabolism, immune response, and

Free access