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Alessandro Pocai Diabetes and Endocrinology, Merck Research Laboratories, Merck Sharp and Dohme Corp., 126 East Lincoln Avenue, Rahway, New Jersey 07065, USA

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peptide (GIP) receptors. Peripheral administration of OXM results in increased c-Fos in the arcuate nucleus (ARC), but not in the brainstem region ( Dakin et al . 2004 ), and using manganese-enhanced magnetic resonance to follow the pattern of neuronal

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0368
Volume/Issue:
Volume 215: Issue 3
Open access
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J Bancroft The Kinsey Institute, Indiana University, Morrison Hall third floor, Bloomington, Indiana 47405, USA

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characterized by peptidergic neurotransmission, contrasting with the synaptic neuronal structure of the cortex ( Herbert 1993 ) and consistent with the more primitive phylogenetic origins of the brainstem. The specific effect of a peptide may depend on its site

Article Type:
Other
DOI:
https://doi.org/10.1677/joe.1.06233
Volume/Issue:
Volume 186: Issue 3
Free access
Masaki Kakeyama Division of Environmental Health Sciences, National Institute for Environmental Studies, Graduate School of Medicine, Center for Disease Biology and Integrative Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
Division of Environmental Health Sciences, National Institute for Environmental Studies, Graduate School of Medicine, Center for Disease Biology and Integrative Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

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Hideko Sone Division of Environmental Health Sciences, National Institute for Environmental Studies, Graduate School of Medicine, Center for Disease Biology and Integrative Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

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Chiharu Tohyama Division of Environmental Health Sciences, National Institute for Environmental Studies, Graduate School of Medicine, Center for Disease Biology and Integrative Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
Division of Environmental Health Sciences, National Institute for Environmental Studies, Graduate School of Medicine, Center for Disease Biology and Integrative Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

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arylhydrocarbon receptor nuclear translocator-2 in the rat brain and brainstem . Journal of Comparative Neurology 427 428 – 439 . Petroff BK Roby KF Gao X Son D Williams S Johnson D Rozman KK Terranova PF 2001 A review of mechanisms controlling

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0062
Volume/Issue:
Volume 197: Issue 2
Free access
Tetsuya Kouno Discovery Research Laboratory for Innovative Frontier Medicines, Discovery Research Laboratory for Core Therapeutic Areas, Department of Biological Chemistry, Shionogi and Co., Ltd, 3-1-1 Futaba-cho, Toyonaka, Osaka 561-0825, Japan
Discovery Research Laboratory for Innovative Frontier Medicines, Discovery Research Laboratory for Core Therapeutic Areas, Department of Biological Chemistry, Shionogi and Co., Ltd, 3-1-1 Futaba-cho, Toyonaka, Osaka 561-0825, Japan

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Nobuteru Akiyama Discovery Research Laboratory for Innovative Frontier Medicines, Discovery Research Laboratory for Core Therapeutic Areas, Department of Biological Chemistry, Shionogi and Co., Ltd, 3-1-1 Futaba-cho, Toyonaka, Osaka 561-0825, Japan

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Takahito Ito Discovery Research Laboratory for Innovative Frontier Medicines, Discovery Research Laboratory for Core Therapeutic Areas, Department of Biological Chemistry, Shionogi and Co., Ltd, 3-1-1 Futaba-cho, Toyonaka, Osaka 561-0825, Japan

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Tomohiko Okuda Discovery Research Laboratory for Innovative Frontier Medicines, Discovery Research Laboratory for Core Therapeutic Areas, Department of Biological Chemistry, Shionogi and Co., Ltd, 3-1-1 Futaba-cho, Toyonaka, Osaka 561-0825, Japan

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Isamu Nanchi Discovery Research Laboratory for Innovative Frontier Medicines, Discovery Research Laboratory for Core Therapeutic Areas, Department of Biological Chemistry, Shionogi and Co., Ltd, 3-1-1 Futaba-cho, Toyonaka, Osaka 561-0825, Japan

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Mitsuru Notoya Discovery Research Laboratory for Innovative Frontier Medicines, Discovery Research Laboratory for Core Therapeutic Areas, Department of Biological Chemistry, Shionogi and Co., Ltd, 3-1-1 Futaba-cho, Toyonaka, Osaka 561-0825, Japan

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Shogo Oka Discovery Research Laboratory for Innovative Frontier Medicines, Discovery Research Laboratory for Core Therapeutic Areas, Department of Biological Chemistry, Shionogi and Co., Ltd, 3-1-1 Futaba-cho, Toyonaka, Osaka 561-0825, Japan

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Hideo Yukioka Discovery Research Laboratory for Innovative Frontier Medicines, Discovery Research Laboratory for Core Therapeutic Areas, Department of Biological Chemistry, Shionogi and Co., Ltd, 3-1-1 Futaba-cho, Toyonaka, Osaka 561-0825, Japan

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‘homeostatic feeding’, such as the hypothalamus and brainstem and also in ‘hedonic feeding’ (feeding linked to a rewarding system, not necessarily accompanied by caloric need), such as the ventral tegmental area and the nucleus accumbens (NAc) ( Naleid et al

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-15-0330
Volume/Issue:
Volume 228: Issue 2
Free access
Jing Li Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China

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Pan-Pan Zhao Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China

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Ting Hao Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China

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Dan Wang Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China

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Yu Wang Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China

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Yang-Zi Zhu Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China

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Yu-Qing Wu Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China
Department of Anesthetic Pharmacology, Xuzhou Medical University, Xuzhou, China

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Cheng-Hua Zhou Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China
Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, China

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. ( doi:10.1016/S0014-5793(99)01003-0 ) Dun SL Brailoiu GC Yang J Chang JK Dun NJ 2001 Urotensin II-immunoreactivity in the brainstem and spinal cord of the rat . Neuroscience Letters 305 9 – 12 . ( doi:10.1016/S0304

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-16-0255
Volume/Issue:
Volume 232: Issue 2
Free access
Z A Archer
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S M Rhind
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P A Findlay
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C E Kyle
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M C Barber
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C L Adam
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Physiology 269 R1099 –R1106. Mercer JG , Moar KM, Findlay PA, Hoggard N & Adam CL 1998 Association of leptin receptor (OB-Rb), NPY and GLP-1 in the ovine and murine brainstem. Regulatory Peptides 75 271 –278

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06013
Volume/Issue:
Volume 184: Issue 3
Free access
Joan Villarroya Departament de Bioquímica i Biomedicina Molecular and Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Catalonia, Spain
CIBER Fisiopatología de la Obesidad y Nutrición, Barcelona, Catalonia, Spain

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Rubén Cereijo Departament de Bioquímica i Biomedicina Molecular and Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Catalonia, Spain
CIBER Fisiopatología de la Obesidad y Nutrición, Barcelona, Catalonia, Spain

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Aleix Gavaldà-Navarro Departament de Bioquímica i Biomedicina Molecular and Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Catalonia, Spain
CIBER Fisiopatología de la Obesidad y Nutrición, Barcelona, Catalonia, Spain

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Marion Peyrou Departament de Bioquímica i Biomedicina Molecular and Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Catalonia, Spain
CIBER Fisiopatología de la Obesidad y Nutrición, Barcelona, Catalonia, Spain

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Marta Giralt Departament de Bioquímica i Biomedicina Molecular and Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Catalonia, Spain
CIBER Fisiopatología de la Obesidad y Nutrición, Barcelona, Catalonia, Spain

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Francesc Villarroya Departament de Bioquímica i Biomedicina Molecular and Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Catalonia, Spain
CIBER Fisiopatología de la Obesidad y Nutrición, Barcelona, Catalonia, Spain

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TGFβ family that is widely recognised as a systemic marker of multiple pathologies, from cardiovascular disease to cancer. Recently, GDF15 has been reported to exert anorexigenic effects through its action at the brainstem and to contribute towards

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-19-0295
Volume/Issue:
Volume 243: Issue 2
Free access
Samira Fargali Departments of, Neuroscience, Medicine, Geriatrics, Box 1065, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, New York 10029, USA

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Thomas Scherer Departments of, Neuroscience, Medicine, Geriatrics, Box 1065, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, New York 10029, USA

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Andrew C Shin Departments of, Neuroscience, Medicine, Geriatrics, Box 1065, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, New York 10029, USA

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Masato Sadahiro Departments of, Neuroscience, Medicine, Geriatrics, Box 1065, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, New York 10029, USA

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Christoph Buettner Departments of, Neuroscience, Medicine, Geriatrics, Box 1065, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, New York 10029, USA
Departments of, Neuroscience, Medicine, Geriatrics, Box 1065, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, New York 10029, USA

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Stephen R Salton Departments of, Neuroscience, Medicine, Geriatrics, Box 1065, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, New York 10029, USA
Departments of, Neuroscience, Medicine, Geriatrics, Box 1065, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, New York 10029, USA

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paraventricular nucleus, innervating parasympathetic and sympathetic preganglionic cells in the brainstem and spinal cord, to form sympathetic circuits that innervate brown adipose tissue (BAT), white adipose tissue (WAT), liver, and pancreas ( Giordano et al

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0172
Volume/Issue:
Volume 215: Issue 2
Free access
Blerina Kola Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Centre for Endocrinology, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK

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Márta Korbonits Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Centre for Endocrinology, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK

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U Chen D Dickson SL 2008 Hypothalamic gene expression following ghrelin therapy to gastrectomized rodents . Regulatory Peptides 146 176 – 182 . Faulconbridge LF Grill HJ Kaplan JM Daniels D 2008 Caudal brainstem delivery of

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-09-0056
Volume/Issue:
Volume 202: Issue 2
Free access
Shin-ya Ueda Department of Sports Medicine, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka 545-8585, Japan

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Takahiro Yoshikawa Department of Sports Medicine, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka 545-8585, Japan

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Yoshihiro Katsura Department of Sports Medicine, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka 545-8585, Japan

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Tatsuya Usui Department of Sports Medicine, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka 545-8585, Japan

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Hayato Nakao Department of Sports Medicine, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka 545-8585, Japan

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Shigeo Fujimoto Department of Sports Medicine, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka 545-8585, Japan

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peripheral signals that change in response to starvation or food intake and act in the hypothalamus and brainstem to alter feelings of hunger or fullness so as to determine meal initiation (hunger) or meal termination (satiety; Bray 2000 , De Graaf et al

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0500
Volume/Issue:
Volume 201: Issue 1
Free access